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Farmorubicin RTU 50mg Injection

Farmorubicin RTU 50mg Injection

Prescription drug
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Synonym

EPIRUBICIN HYDROCHLORIDE

Composition

EPIRUBICIN-50MG

Manufacturer/Marketer

Pfizer Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

for this medicine

About Farmorubicin RTU 50mg Injection

Farmorubicin RTU 50mg Injection is an anti-cancer medicine that is used in conjunction with other drugs to treat breast cancer in people who have had tumor removal surgery. Farmorubicin RTU 50mg Injection is used as adjuvant chemotherapy in women with axillary lymph nodes with involvement resection of breast cancer (abnormal growth in the cells of the breast).

Farmorubicin RTU 50mg Injection contains Epirubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis.

Farmorubicin RTU 50mg Injection may cause certain side effects such as nausea, headache, abdominal pain, loss of appetite, vomiting, dizziness, mouth sores, tiredness, back pain, diarrhoea, and pain at the site of injection. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor. A trained healthcare doctor will administer Farmorubicin RTU 50mg Injection. So, do not self-administer. Your doctor will decide the dose of the medicine based on your health condition.

Farmorubicin RTU 50mg Injection should be avoided if you are allergic to it. It is contraindicated in patients having a recent history of myocardial infarction (MI) or heart attack, patients with baseline neutrophil count < 1500 cells/mm3, severe arrhythmias, previous treatment with anthracyclines, and severe hepatic dysfunction. Hence avoid using this medicine under such conditions. Inform your doctor if you have any cardiovascular conditions, liver/kidney disease, or taking any medicines such as cardiotoxic drugs (eg, Thalidomide, doxorubicin, Abiraterone, tamoxifen, letrozole), and cimetidine, as it can cause serious adverse effects. Farmorubicin RTU 50mg Injection is known to cause embryo-fetal toxicity. Hence it is contraindicated in pregnant or breastfeeding women. Farmorubicin RTU 50mg Injection is not recommended for children as it is known to cause anthracycline-induced acute manifestations of cardiotoxicity and chronic CHF.

Uses of Farmorubicin RTU 50mg Injection

Treatment of Breast Cancer

Medicinal Benefits

Farmorubicin RTU 50mg Injection contains Epirubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis. It is used as adjuvant chemotherapy in women with axillary lymph nodes with involvement resection of breast cancer.

Directions for Use

A trained healthcare professional will administer Farmorubicin RTU 50mg Injection. Hence, do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Farmorubicin RTU 50mg Injection

  • Nausea
  • Abdominal pain
  • Vomiting
  • Dizziness
  • Back pain
  • Pain at the site of injection
  • Red discoloration of urine
  • Loss of appetite
  • Mouth sores
  • Tiredness
  • Weight gain
  • Pale skin

Drug Warnings

Farmorubicin RTU 50mg Injection should be avoided if you are allergic to it. It is contraindicated in patients having a recent history of myocardial infarction (MI) or heart attack, patients with baseline neutrophil count < 1500 cells/mm3, severe arrhythmias, previous treatment with anthracyclines and severe hepatic dysfunction. Hence avoid using this medicine under such conditions. Inform your doctor if you have any cardiovascular conditions, liver/kidney disease, or taking any medicines such as cardiotoxic drugs (e.g., Thalidomide, doxorubicin, Abiraterone, tamoxifen, letrozole), and cimetidine, as it can cause serious adverse effects. Farmorubicin RTU 50mg Injection is known to cause embryo-fetal toxicity. Hence it is contraindicated in pregnant or breastfeeding women. Farmorubicin RTU 50mg Injection is not recommended for children as it is known to cause anthracycline-induced acute manifestations of cardiotoxicity and chronic CHF. Do not stop receiving Farmorubicin RTU 50mg Injection without a doctor’s advice, as it can cause serious health conditions. Farmorubicin RTU 50mg Injection is known to cause severe life-threatening haematological reactions, tissue necrosis, cardiomyopathy, secondary acute myelogenous leukaemia, and severe myelosuppression in some patients. Hence careful monitoring of the patient is needed while receiving the medicine.

Drug Interactions

Drug-Drug Interactions: Farmorubicin RTU 50mg Injection may interact with cardiotoxic drugs (e.g., Thalidomide, doxorubicin, Abiraterone, tamoxifen, letrozole), antimicrotubular agents ((paclitaxel, docetaxel), antihistamine (cimetidine), calcium channel blockers (cilnidipine, nifedipine).

Drug-Food Interactions: Avoid smoking and alcohol consumption.

Drug-Disease Interactions: Inform your doctor if you have cardiac problems, liver or kidney disease, heart attack, severe MI, or cardiomyopathy.

Drug-Drug Interactions Checker List

  • THALIDOMIDE
  • DOXORUBICIN
  • ABIRATERONE
  • TAMOXIFEN
  • LETROZOLE
  • PACLITAXEL
  • DOCETAXEL
  • CIMETIDINE
  • CILNIDIPINE
  • NIFEDIPINE

Habit Forming

No

Diet & Lifestyle Advise

  • Try to eat more healthy fats, fruits, vegetables and whole-grain foods to give you more energy. 
  • Stay hydrated by drinking plenty of water, as dehydration is often seen in cancers.
  • Taking a stroll in the garden or spending 30 minutes of your time doing some light physical activity can be very useful. However, do not over-exert yourself if you feel too tired. 
  • Avoid smoking and alcohol consumption.
  • Doing meditation and yoga for some time is very effective in helping cancer patients maintain a healthy attitude and body.

Special Advise

  • Avoid having intercourse while on treatment with Farmorubicin RTU 50mg Injection.
  • Regular monitoring of complete blood count  (CBC) and liver function (LFT) is important while receiving Farmorubicin RTU 50mg Injection.

Disease/Condition Glossary

Breast Cancer: Breast cancer is a type of cancer with abnormal growth in the cells of the breast. There are different kinds of breast cancer, such as cancer occurring in lobules (glands that produce milk), ducts of the breast (the pathway that brings milk from glands to the nipple), and in the fatty tissue or the fibrous connective tissue within the breast. Symptoms of breast cancer include a lump in the breast, breast pain, redness, swelling, nipple discharge other than breast milk, bloody discharge, a lump or swelling under the arm, unexplained change in shape, size or appearance of the breast, peeling, flaking or scaling of the skin.

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Alcohol

Unsafe

Alcohol intake might increase the risk of stomach or intestine bleeding. Alcohol consumption is not recommended.

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Pregnancy

Unsafe

Farmorubicin RTU 50mg Injection is not recommended for use in pregnancy as it may harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Farmorubicin RTU 50mg Injection. Use reliable methods of birth control while on treatment with Farmorubicin RTU 50mg Injection.

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Breast Feeding

Unsafe

It is not recommended for use in breastfeeding as it may pass into breast milk and harm your infant. Hence, if you are breastfeeding, inform your doctor before receiving Farmorubicin RTU 50mg Injection. Your doctor may suggest you stop feeding while on treatment with this medicine.

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Driving

Safe

Farmorubicin RTU 50mg Injection does not affect your ability to drive. However, drive only if you are alert.

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Liver

Caution

Farmorubicin RTU 50mg Injection should be used with caution in patients with liver impairment. However, this medicine is contraindicated in patients with severe liver disease. If you have a pre-existing or a history of liver disease, inform your doctor. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor. Your doctor may adjust the dose or prescribe a suitable alternative, if necessary, based on your condition.

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Children

Unsafe

Farmorubicin RTU 50mg Injection is not recommended for use in children, as it is known to cause anthracycline-induced acute manifestations of cardiotoxicity and chronic CHF leading to serious side effects.

Country of origin

India

Manufacturer/Marketer address

Bombay Tablet Mfg. Co. Pvt. Ltd., Off. 304, S. Gandhi Marg, Mumbai - 400 002.
Other Info - FA79073

FAQs

Farmorubicin RTU 50mg Injection is used to treat Breast Cancer.
Farmorubicin RTU 50mg Injection contains Epirubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis.
Farmorubicin RTU 50mg Injection can disrupt a woman's natural menstrual cycle (period) and inhibit sperm production in men. However, you should not presume that you cannot become pregnant or that you cannot make someone else pregnant. It may also harm your foetus. Use reliable methods of birth control while on treatment with Farmorubicin RTU 50mg Injection.

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