Epialfa 50mg Injection
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MRP ₹1500
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MRP ₹1500
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Epialfa 50mg Injection is an anti-cancer medicine that is used in conjunction with other drugs to treat breast cancer in people who have had tumor removal surgery. Epialfa 50mg Injection is used as adjuvant chemotherapy in women with axillary lymph nodes with involvement resection of breast cancer (abnormal growth in the cells of the breast).
Epialfa 50mg Injection contains Epirubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis.
Epialfa 50mg Injection may cause certain side effects such as nausea, headache, abdominal pain, loss of appetite, vomiting, dizziness, mouth sores, tiredness, back pain, diarrhoea, and pain at the site of injection. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor. A trained healthcare doctor will administer Epialfa 50mg Injection. So, do not self-administer. Your doctor will decide the dose of the medicine based on your health condition.
Epialfa 50mg Injection should be avoided if you are allergic to it. It is contraindicated in patients having a recent history of myocardial infarction (MI) or heart attack, patients with baseline neutrophil count < 1500 cells/mm3, severe arrhythmias, previous treatment with anthracyclines, and severe hepatic dysfunction. Hence avoid using this medicine under such conditions. Inform your doctor if you have any cardiovascular conditions, liver/kidney disease, or taking any medicines such as cardiotoxic drugs (eg, Thalidomide, doxorubicin, Abiraterone, tamoxifen, letrozole), and cimetidine, as it can cause serious adverse effects. Epialfa 50mg Injection is known to cause embryo-fetal toxicity. Hence it is contraindicated in pregnant or breastfeeding women. Epialfa 50mg Injection is not recommended for children as it is known to cause anthracycline-induced acute manifestations of cardiotoxicity and chronic CHF.
Epialfa 50mg Injection contains Epirubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis. It is used as adjuvant chemotherapy in women with axillary lymph nodes with involvement resection of breast cancer.
Epialfa 50mg Injection should be avoided if you are allergic to it. It is contraindicated in patients having a recent history of myocardial infarction (MI) or heart attack, patients with baseline neutrophil count < 1500 cells/mm3, severe arrhythmias, previous treatment with anthracyclines and severe hepatic dysfunction. Hence avoid using this medicine under such conditions. Inform your doctor if you have any cardiovascular conditions, liver/kidney disease, or taking any medicines such as cardiotoxic drugs (e.g., Thalidomide, doxorubicin, Abiraterone, tamoxifen, letrozole), and cimetidine, as it can cause serious adverse effects. Epialfa 50mg Injection is known to cause embryo-fetal toxicity. Hence it is contraindicated in pregnant or breastfeeding women. Epialfa 50mg Injection is not recommended for children as it is known to cause anthracycline-induced acute manifestations of cardiotoxicity and chronic CHF. Do not stop receiving Epialfa 50mg Injection without a doctor’s advice, as it can cause serious health conditions. Epialfa 50mg Injection is known to cause severe life-threatening haematological reactions, tissue necrosis, cardiomyopathy, secondary acute myelogenous leukaemia, and severe myelosuppression in some patients. Hence careful monitoring of the patient is needed while receiving the medicine.
Drug-Drug Interactions: Epialfa 50mg Injection may interact with cardiotoxic drugs (e.g., Thalidomide, doxorubicin, Abiraterone, tamoxifen, letrozole), antimicrotubular agents ((paclitaxel, docetaxel), antihistamine (cimetidine), calcium channel blockers (cilnidipine, nifedipine).
Drug-Food Interactions: Avoid smoking and alcohol consumption.
Drug-Disease Interactions: Inform your doctor if you have cardiac problems, liver or kidney disease, heart attack, severe MI, or cardiomyopathy.
Breast Cancer: Breast cancer is a type of cancer with abnormal growth in the cells of the breast. There are different kinds of breast cancer, such as cancer occurring in lobules (glands that produce milk), ducts of the breast (the pathway that brings milk from glands to the nipple), and in the fatty tissue or the fibrous connective tissue within the breast. Symptoms of breast cancer include a lump in the breast, breast pain, redness, swelling, nipple discharge other than breast milk, bloody discharge, a lump or swelling under the arm, unexplained change in shape, size or appearance of the breast, peeling, flaking or scaling of the skin.
Alcohol
Unsafe
Alcohol intake might increase the risk of stomach or intestine bleeding. Alcohol consumption is not recommended.
Pregnancy
Unsafe
Epialfa 50mg Injection is not recommended for use in pregnancy as it may harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Epialfa 50mg Injection. Use reliable methods of birth control while on treatment with Epialfa 50mg Injection.
Breast Feeding
Unsafe
It is not recommended for use in breastfeeding as it may pass into breast milk and harm your infant. Hence, if you are breastfeeding, inform your doctor before receiving Epialfa 50mg Injection. Your doctor may suggest you stop feeding while on treatment with this medicine.
Driving
Safe
Epialfa 50mg Injection does not affect your ability to drive. However, drive only if you are alert.
Liver
Caution
Epialfa 50mg Injection should be used with caution in patients with liver impairment. However, this medicine is contraindicated in patients with severe liver disease. If you have a pre-existing or a history of liver disease, inform your doctor. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.
Kidney
Caution
If you have a pre-existing or a history of kidney disease, inform your doctor. Your doctor may adjust the dose or prescribe a suitable alternative, if necessary, based on your condition.
Children
Unsafe
Epialfa 50mg Injection is not recommended for use in children, as it is known to cause anthracycline-induced acute manifestations of cardiotoxicity and chronic CHF leading to serious side effects.
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