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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 22, 2024 | 7:37 PM IST

Eptus-T 20 Tablet is used to remove excess water from the body. It also maintains the bloodstream's potassium level and prevents hypertension (high blood pressure) due to oedema (fluid retention). It works by increasing the amount of urine that is passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it also helps lower high blood pressure, reducing the chances of any future heart attack, stroke or angina (chest pain) in the future. In some cases, you may experience dehydration, electrolyte disturbances (calcium, magnesium, and sodium), constipation, itching, and increased uric acid.

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Manufacturer/Marketer

Glenmark Pharmaceuticals Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Eptus-T 20 Tablet

Eptus-T 20 Tablet belongs to a class of medicine called 'diuretics' (water pills) primarily used to remove excess water from the body. It also maintains the bloodstream's potassium level and prevents hypertension (high blood pressure) due to oedema (fluid retention). Oedema or fluid overload is associated with pulmonary hypertension (high blood pressure in the lung) or heart failure (irregular heart pumping). Leg swelling is the main characteristic of oedema, accompanied by shortness of breath, chest pain (angina), abnormal heart rhythms (arrhythmia) and swelling in other hands or abdomen areas.

Eptus-T 20 Tablet is a combination of medications containing Eplerenone and Torsemide, which are prescribed for the treatment of resistant oedema (fluid overload) associated with pulmonary hypertension (high blood pressure in the lungs), heart failure and hepatic cirrhosis (chronic liver damage). Eptus-T 20 Tablet works by increasing the amount of urine that is passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it also helps lower high blood pressure, reducing the chances of any future heart attack, stroke or angina (chest pain) in the future.

Take Eptus-T 20 Tablet as prescribed by your doctor. Depending upon your medical condition, you are advised to take Eptus-T 20 Tablet for as long as your doctor has prescribed it for you. In some cases, you may experience dehydration, electrolyte disturbances (calcium, magnesium, and sodium), constipation, itching, and increased uric acid. Most of these side effects of Eptus-T 20 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking a Eptus-T 20 Tablet of your own, as doing so may raise your blood pressure, thereby increasing the risk of heart disease and stroke. Inform your doctor if you are suffering from kidney, liver or heart disease. If you are pregnant or breastfeeding, please tell your doctor so that the dosage of Eptus-T 20 Tablet can be prescribed accordingly. Please tell your doctor if you are taking any other medicines or are allergic to the Eptus-T 20 Tablet . Reducing the amount of table salt (sodium chloride) in your food often relieves the body's swelling.

Uses of Eptus-T 20 Tablet

Treatment of Oedema (fluid overload)

Medicinal Benefits

Eptus-T 20 Tablet is primarily used to remove excess water from the body. It also maintains the bloodstream's potassium level and prevents hypertension (high blood pressure) due to oedema (fluid retention). Eptus-T 20 Tablet is a combination of medications containing Eplerenone and Torsemide. Both Eplerenone and Torsemide are diuretics and are prescribed for the treatment of resistant oedema (fluid overload) associated with pulmonary hypertension (high blood pressure in the lungs), heart failure and hepatic cirrhosis (chronic liver damage). Eptus-T 20 Tablet works by increasing the amount of urine that is passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it also helps lower high blood pressure, reducing the chances of any future heart attack, stroke or angina (chest pain) in the future.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Eptus-T 20 Tablet

  • Dehydration
  • Electrolyte disturbances (calcium, magnesium, and sodium)
  • Constipation
  • Itching
  • Increased uric acid

Drug Warnings

Eptus-T 20 Tablet should not be given to the people allergic to Eptus-T 20 Tablet , have low blood pressure (less than 90 mm of Hg), have had a heart attack, kidney disease (with creatinine clearance less than 30 mL/min), liver disease, pregnant women, or planning to get pregnant and breastfeeding women. Besides this, it is contraindicated in low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart), and aortic stenosis (heart valve problem). Eptus-T 20 Tablet can pass into breast milk, but its effect on the baby is unknown, so it is better to tell your doctor if you are taking Eptus-T 20 Tablet and breastfeeding. Dehydration with electrolyte and acid-base disturbances must be corrected before using Eptus-T 20 Tablet . Do not take any extra potassium supplements or potassium-rich foods such as bananas and broccoli with Eptus-T 20 Tablet . It may lead to an excessive increase in blood potassium levels (hyperkalemia). Please take Eptus-T 20 Tablet at least 4 hours before sleeping to avoid frequent urination at night.

Drug Interactions

Drug-Drug Interactions: Eptus-T 20 Tablet may interact with other high blood pressure-lowering pills (metoprolol, ramipril, hydrochlorothiazide, rosuvastatin, atorvastatin), and it can lower your blood pressure leading to severe condition. Besides this, it also interacts with medicine to treat blood thinners (aspirin, warfarin), anti-epilepsy medications (carbamazepine, phenobarbital), immune-suppressing drugs (cyclosporine), painkillers (ibuprofen), azole antifungals (ketaconazole, itraconazole),  HIV protease inhibitors  (nelfinavir, ritonavir).

Drug-Food Interactions: You are recommended not to consume alcohol with a Eptus-T 20 Tablet to avoid unpleasant side effects.

Drug-Disease Interactions: Eptus-T 20 Tablet may interact with disease conditions, including cardiogenic shock (when the heart fails to pump required blood to the body), heart valve problem (stenosis), low blood pressure (hypotension), coronary heart disease, liver disease, or heart failure, low serum potassium (hypokalemia) and patients with nil urine output (anuria).

Drug-Drug Interactions Checker List

  • METOPROLOL
  • RAMIPRIL
  • HYDROCHLOROTHIAZIDE
  • ROSUVASTATIN
  • ATORVASTATIN
  • ASPIRIN
  • WARFARIN
  • CARBAMAZEPINE
  • PHENOBARBITAL
  • CYCLOSPORINE
  • IBUPROFEN

Habit Forming

No

Diet & Lifestyle Advise

  • Consume antioxidant-rich food. Blueberries, cherries, tomatoes, squash, and bell peppers are high in antioxidants.
  • Eat natural diuretic foods. Asparagus, beets, green beans, grapes, onion, leafy greens, pineapple, leeks, pumpkin, and garlic are all-natural diuretic foods.
  • Use healthy cooking oils like soybean, olive, canola, and coconut oil.
  • You should avoid refined foods such as white bread, spaghetti, sugar, and red meat.
  • Reduce or eliminate Trans fatty acids, which are found in commercially baked items such as cookies, cakes, crackers, French fries, onion rings, doughnuts, and processed foods.
  • Avoid the consumption of too much salt or salty food.
  • Keep your weight under control with a BMI of 19.5-24.9.
  • Regular physical activity or exercise like walking improves your blood flow.
  • When possible, elevate your legs or the swollen area on a chair or pillows.
  • Avoid standing or sitting for extended periods of time.
  • Avoid chronic stress, as it can raise your blood pressure.
  • Spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Quitting smoking and alcohol consumption is the best strategy to lower the risk of many health complications.

Special Advise

  • Treatment with Eptus-T 20 Tablet requires regular monitoring of serum potassium, sodium and creatinine levels.
  • Monitor your blood pressure daily, and if there is too much fluctuation, immediately contact your doctor.
  • Regular monitoring of uric acid in patients with gouty arthritis.

Disease/Condition Glossary

Oedema: Oedema or fluid overload is associated with pulmonary hypertension (high blood pressure in the lung) or heart failure (irregular pumping of the heart). The main characteristics of oedema are leg swelling,  shortness of breath, chest pain (angina), abnormal heart rhythms (arrhythmia) and swelling in other hands or abdomen areas.

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Alcohol

Caution

You are recommended not to consume alcohol along with Eptus-T 20 Tablet to avoid unpleasant side effects.

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Pregnancy

Caution

Eptus-T 20 Tablet should not be used during pregnancy unless clearly necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Eptus-T 20 Tablet .

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Breast Feeding

Caution

Eptus-T 20 Tablet should not be used in nursing mothers unless clearly necessary. So, inform your doctor if you are a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Eptus-T 20 Tablet .

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Driving

Caution

It is not recommended to drive after taking Eptus-T 20 Tablet as it may occasionally cause drowsiness due to orthostatic hypotension (sudden drop in blood pressure on standing from lying position).

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Liver

Caution

Eptus-T 20 Tablet to be taken with caution, especially if you have a history of Liver diseases/conditions. Your doctor may adjust your dose depending on your current kidney conditions.

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Kidney

Caution

Eptus-T 20 Tablet to be taken with caution, especially if you have a history of Kidney diseases. Your doctor may adjust your dose depending on your current kidney conditions.

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Children

Unsafe

Eptus-T 20 Tablet is not recommended for children below 12 years of age.

Country of origin

India

Manufacturer/Marketer address

Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai – 400 026.
Other Info - EPT0038

Author Details

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FAQs

Eptus-T 20 Tablet is used to treat oedema (fluid overload).
Eptus-T 20 Tablet works by increasing the amount of urine that is passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it also helps lower high blood pressure, reducing the chances of any future heart attack, stroke or angina (chest pain) in the future.
The main side effect of Eptus-T 20 Tablet is peeing (urination) more often than normal. Most people need to pee about 30 minutes after taking Eptus-T 20 Tablet and again within a few hours. Do not take Eptus-T 20 Tablet before going to bed, or you may have to wake up at night to go for urination frequently.
Yes, the Eptus-T 20 Tablet is known to cause dehydration (excessive loss of fluids). The patient may experience dry mouth, decreased urine output, excessive thirst, and hypotension (decreased blood pressure). So, please increase the intake of fluids to avoid extreme dehydration.
Yes, Eptus-T 20 Tablet can cause increased potassium levels (hyperkalemia), especially in patients with kidney problems or if you are taking potassium supplements along with Eptus-T 20 Tablet . Please monitor your electrolyte level regularly to avoid increased blood potassium levels.
Yes, Eptus-T 20 Tablet may occasionally cause dizziness due to orthostatic hypotension (sudden drop in blood pressure when standing from a lying position) or passing out. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
Eptus-T 20 Tablet should be swallowed as a whole with water; do not crush or chew it.
Eptus-T 20 Tablet should be taken with caution and only if prescribed by the doctor if you have kidney or liver disease. Please consult the doctor if you have any concerns.
Eptus-T 20 Tablet may cause side effects like dehydration, electrolyte disturbances (calcium, magnesium, and sodium), constipation, itching, and increased uric acid. If the side effects are persistent, reach out to your doctor.
Treatment with Eptus-T 20 Tablet requires regular monitoring of serum potassium, sodium and creatinine levels. Monitor your blood pressure daily, and if there is too much fluctuation, immediately contact your doctor. Regular monitoring of uric acid in patients with gouty arthritis.
Other medications can be taken with Eptus-T 20 Tablet only if advised by the doctor. Please consult the doctor before taking other medicines with Eptus-T 20 Tablet to prevent any interactions.

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