Epnone-T20 Combikit Tablet belongs to a class of medicine called 'diuretics' (water pills) primarily used to remove excess water from the body. It also maintains the bloodstream's potassium level and prevents hypertension (high blood pressure) due to oedema (fluid retention). Oedema or fluid overload is associated with pulmonary hypertension (high blood pressure in the lung) or heart failure (irregular heart pumping). Leg swelling is the main characteristic of oedema, accompanied by shortness of breath, chest pain (angina), abnormal heart rhythms (arrhythmia) and swelling in other hands or abdomen areas.

Epnone-T20 Combikit Tablet is a combination of medications containing Eplerenone and Torsemide, which are prescribed for the treatment of resistant oedema (fluid overload) associated with pulmonary hypertension (high blood pressure in the lungs), heart failure and hepatic cirrhosis (chronic liver damage). Epnone-T20 Combikit Tablet works by increasing the amount of urine that is passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it also helps lower high blood pressure, reducing the chances of any future heart attack, stroke or angina (chest pain) in the future.

Take Epnone-T20 Combikit Tablet as prescribed by your doctor. Depending upon your medical condition, you are advised to take Epnone-T20 Combikit Tablet for as long as your doctor has prescribed it for you. In some cases, you may experience dehydration, electrolyte disturbances (calcium, magnesium, and sodium), constipation, itching, and increased uric acid. Most of these side effects of Epnone-T20 Combikit Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking a Epnone-T20 Combikit Tablet of your own, as doing so may raise your blood pressure, thereby increasing the risk of heart disease and stroke. Inform your doctor if you are suffering from kidney, liver or heart disease. If you are pregnant or breastfeeding, please tell your doctor so that the dosage of Epnone-T20 Combikit Tablet can be prescribed accordingly. Please tell your doctor if you are taking any other medicines or are allergic to the Epnone-T20 Combikit Tablet . Reducing the amount of table salt (sodium chloride) in your food often relieves the body's swelling.

Epnone-T20 Combikit Tablet is primarily used to remove excess water from the body. It also maintains the bloodstream's potassium level and prevents hypertension (high blood pressure) due to oedema (fluid retention). Epnone-T20 Combikit Tablet is a combination of medications containing Eplerenone and Torsemide. Both Eplerenone and Torsemide are diuretics and are prescribed for the treatment of resistant oedema (fluid overload) associated with pulmonary hypertension (high blood pressure in the lungs), heart failure and hepatic cirrhosis (chronic liver damage). Epnone-T20 Combikit Tablet works by increasing the amount of urine that is passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it also helps lower high blood pressure, reducing the chances of any future heart attack, stroke or angina (chest pain) in the future.

• Dehydration
• Electrolyte disturbances (calcium, magnesium, and sodium)
• Constipation
• Itching
• Increased uric acid

Epnone-T20 Combikit Tablet should not be given to the people allergic to Epnone-T20 Combikit Tablet , have low blood pressure (less than 90 mm of Hg), have had a heart attack, kidney disease (with creatinine clearance less than 30 mL/min), liver disease, pregnant women, or planning to get pregnant and breastfeeding women. Besides this, it is contraindicated in low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart), and aortic stenosis (heart valve problem). Epnone-T20 Combikit Tablet can pass into breast milk, but its effect on the baby is unknown, so it is better to tell your doctor if you are taking Epnone-T20 Combikit Tablet and breastfeeding. Dehydration with electrolyte and acid-base disturbances must be corrected before using Epnone-T20 Combikit Tablet . Do not take any extra potassium supplements or potassium-rich foods such as bananas and broccoli with Epnone-T20 Combikit Tablet . It may lead to an excessive increase in blood potassium levels (hyperkalemia). Please take Epnone-T20 Combikit Tablet at least 4 hours before sleeping to avoid frequent urination at night.

Drug-Drug Interactions: Epnone-T20 Combikit Tablet may interact with other high blood pressure-lowering pills (metoprolol, ramipril, hydrochlorothiazide, rosuvastatin, atorvastatin), and it can lower your blood pressure leading to severe condition. Besides this, it also interacts with medicine to treat blood thinners (aspirin, warfarin), anti-epilepsy medications (carbamazepine, phenobarbital), immune-suppressing drugs (cyclosporine), painkillers (ibuprofen), azole antifungals (ketaconazole, itraconazole),  HIV protease inhibitors  (nelfinavir, ritonavir).

Drug-Food Interactions: You are recommended not to consume alcohol with a Epnone-T20 Combikit Tablet to avoid unpleasant side effects.

Drug-Disease Interactions: Epnone-T20 Combikit Tablet may interact with disease conditions, including cardiogenic shock (when the heart fails to pump required blood to the body), heart valve problem (stenosis), low blood pressure (hypotension), coronary heart disease, liver disease, or heart failure, low serum potassium (hypokalemia) and patients with nil urine output (anuria).

• METOPROLOL
• RAMIPRIL
• HYDROCHLOROTHIAZIDE
• ROSUVASTATIN
• ATORVASTATIN
• ASPIRIN
• WARFARIN
• CARBAMAZEPINE
• PHENOBARBITAL
• CYCLOSPORINE
• IBUPROFEN

• Consume antioxidant-rich food. Blueberries, cherries, tomatoes, squash, and bell peppers are high in antioxidants.
• Eat natural diuretic foods. Asparagus, beets, green beans, grapes, onion, leafy greens, pineapple, leeks, pumpkin, and garlic are all-natural diuretic foods.
• Use healthy cooking oils like soybean, olive, canola, and coconut oil.
• You should avoid refined foods such as white bread, spaghetti, sugar, and red meat.
• Reduce or eliminate Trans fatty acids, which are found in commercially baked items such as cookies, cakes, crackers, French fries, onion rings, doughnuts, and processed foods.
• Avoid the consumption of too much salt or salty food.
• Keep your weight under control with a BMI of 19.5-24.9.
• Regular physical activity or exercise like walking improves your blood flow.
• When possible, elevate your legs or the swollen area on a chair or pillows.
• Avoid standing or sitting for extended periods of time.
• Avoid chronic stress, as it can raise your blood pressure.
• Spend time with your loved ones to cope with stress and practice mindfulness techniques.
• Quitting smoking and alcohol consumption is the best strategy to lower the risk of many health complications.

• Treatment with Epnone-T20 Combikit Tablet requires regular monitoring of serum potassium, sodium and creatinine levels.
• Monitor your blood pressure daily, and if there is too much fluctuation, immediately contact your doctor.
• Regular monitoring of uric acid in patients with gouty arthritis.

Oedema: Oedema or fluid overload is associated with pulmonary hypertension (high blood pressure in the lung) or heart failure (irregular pumping of the heart). The main characteristics of oedema are leg swelling,  shortness of breath, chest pain (angina), abnormal heart rhythms (arrhythmia) and swelling in other hands or abdomen areas.