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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 23, 2024 | 4:48 PM IST
Dostabil AD 25 Tablet is used to treat depression and anxiety. It contains Dothiepin which works by increasing the levels of chemical messengers responsible for mood. In some cases, this medicine may cause side effects such as restlessness, irritability, tiredness, difficulty concentrating, and sleep disturbances. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Prescription drug

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Composition

DOTHIEPIN-25MG

Manufacturer/Marketer

Lakarez Pharmaceuticals Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-26

for this medicine

About Dostabil AD 25 Tablet

Dostabil AD 25 Tablet belongs to the class of tricyclic antidepressants used to treat depression. It is primarily used to treat depression that is unresponsive to other antidepressants or any other alternative treatment. It is also used to treat disorders related to anxiety. Depression is a mood disorder that affects day to day life of a person. A person may have symptoms such as feeling sad or feeling lost and might have mood swings. Anxiety is defined as an emotion that is characterized by feelings of tension, worried thoughts and symptoms like increased blood pressure. Anxiety disorder also includes panic disorder which is characterized by sudden feelings of terror.

Dostabil AD 25 Tablet contains ‘Dothiepin’ that works by increasing the levels of chemical messengers responsible for stabilizing and elevating the mood levels in the brain. It also stops your brain from releasing the chemicals which cause anxiety. It provides relief from symptoms such as feelings of restlessness, irritability, tiredness, difficulty concentrating, feeling and sleep disturbances. It helps to carry out daily activities easily.

Take this medicine as prescribed by your doctor. In some cases, you may experience side effects such as increased heart rate, blurred vision, dizziness, dryness in the mouth and constipation. Most of these side effects of Dostabil AD 25 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

It is not recommended to take Dostabil AD 25 Tablet if you are allergic to any contents of it. Do not stop taking this medicine without consulting your doctor, as it may lead to withdrawal symptoms. Do not take this medicine if you have any lung disease, muscle weakness (myasthenia gravis), sleeping disorder or difficulty in sleeping (sleep apnea), severe liver disease or problem with alcohol or other prescription recreational drugs. Inform your doctor if you are planning to get pregnant, are pregnant or breastfeeding. Dostabil AD 25 Tablet is not recommended for use in children. In elderly people, Dostabil AD 25 Tablet may require dose adjustments. Do not take alcohol while using Dostabil AD 25 Tablet as it increases the risk of side effects. Dostabil AD 25 Tablet may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.

Uses of Dostabil AD 25 Tablet

Treatment of Depression, Anxiety.

Medicinal Benefits

Dostabil AD 25 Tablet works by increasing the levels of chemical messengers that are responsible for stabilizing and elevating mood levels in the brain. It also stops your brain from releasing the chemicals which cause anxiety. Dostabil AD 25 Tablet relieves symptoms such as restlessness, irritability, tiredness, difficulty concentrating and disturbances in sleep. It helps to carry out daily activities easily and improves the quality of life.

Directions for Use

Take this medicine as prescribed by your doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it. The dose and duration are given by the doctor based on your health condition.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Dostabil AD 25 Tablet

  • Increased heart rate
  • Arrhythmias
  • Blurred vision
  • Dizziness
  • Dryness in the mouth
  • Weight gain
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Weight gain
  • Difficulty in urination
  • Constipation

Drug Warnings

Dostabil AD 25 Tablet should be given with extreme caution in patients having epilepsy (brain disorder in which brain activity becomes abnormal, causing seizures), impaired liver or kidney function, diabetes, decreased level of sodium in the blood, tendency to develop bleedings or bruises easily, patients receiving electroconvulsive treatment, having coronary heart disease, suffering or have suffered from heart problems or have recently had a heart attack, having a low resting heart-rate, having prolonged severe diarrhoea and vomiting (being sick) or using diuretics (water tablets), experiencing a fast or irregular heartbeat, fainting, collapse or dizziness on standing up, which may indicate abnormal functioning of the heart rate and having or previously had eye problems, such as certain kinds of glaucoma (increased pressure in the eye).

Drug Interactions

Drug-Drug Interactions: This medicine may interact with other anti-depressants (phenelzine, iproniazid, isocarboxazid, nialamide, imipramine, desipramine, tranylcypromine and moclobemide), medicines used to treat Parkinson's disease (selegiline). Taking the above medicines with Dostabil AD 25 Tablet can increase the risk of side effects. It can also have an interaction with an antibiotic (linezolid), a medicine used in the treatment of the manic-depressive disorder (lithium), a medicine used to treat migraines (sumatriptan), a medicine used for severe pain such (as tramadol), medicines used for stomach ulcers (cimetidine, lansoprazole and omeprazole), a medicine used to treat fungal infections (fluconazole), a medicine used to reduce the risk of stroke (ticlopidine), a herbal remedy used for depression (Hypericum perforatum), blood-thinning medicines (warfarin, dipyridamole and phenprocoumon), antimalarials (mefloquine), medicines used for heart diseases (flecainide and propafenone). Dostabil AD 25 Tablet may also interact with medicines that decrease blood levels of potassium or magnesium, as these increase the risk of life-threatening heart rhythm disorder.

Drug-Food Interactions: No interactions found. 

Drug-Disease Interactions: People who are overweight or obese (with a BMI greater than 25) should consult a doctor before taking Dostabil AD 25 Tablet .

Drug-Drug Interactions Checker List

  • PHENELZINE
  • ISOCARBOXAZID
  • IMIPRAMINE
  • DESIPRAMINE
  • TRANYLCYPROMINE
  • MOCLOBEMIDE
  • SELEGILINE
  • LINEZOLID
  • LITHIUM
  • SUMATRIPTAN
  • TRAMADOL
  • CIMETIDINE
  • LANSOPRAZOLE
  • OMEPRAZOLE
  • FLUCONAZOLE
  • TICLOPIDINE
  • HYPERICUM PERFORATUM
  • WARFARIN
  • DIPYRIDAMOLE
  • PHENPROCOUMON
  • MEFLOQUINE
  • FLECAINIDE
  • PROPAFENONE
  • IPRONIAZID
  • NIALAMIDE

Habit Forming

No

Diet & Lifestyle Advise

  • Opt for healthy food, which in turn will help you to elevate your moods.
  • Exercise daily for at least 30 minutes a day. It will help you to reduce stress and improve your mood. It will also improve your quality of sleep.
  • Take deep breaths to calm your mind.
  • Follow a consistent sleep schedule (at least 8 hours a day).
  • Manage your stress levels by doing activities that make you happy such as watching your favourite show, reading a book, listening to music and doing activities of your interest.

Special Advise

Do not stop taking Dostabil AD 25 Tablet without consulting your doctor. You may experience side effects if you stop taking it suddenly. Your doctor will most likely advise you to gradually reduce your dose over several weeks before completely discontinuing it.

Disease/Condition Glossary

Depression: It is a mood disorder that has an impact on a person's daily life. Symptoms such as melancholy or loss, as well as mood changes, may occur.

Anxiety: It is characterised by tension, anxious thoughts, and symptoms such as elevated blood pressure. Panic disorder is a type of anxiety disorder marked by unexpected feelings of terror.

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Alcohol

Unsafe

Do not consume alcohol while taking Dostabil AD 25 Tablet as it may cause serious side effects.

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Pregnancy

Unsafe

Dostabil AD 25 Tablet is not recommended for use in pregnancy. If you are pregnant, please inform your doctor before taking this medicine.

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Breast Feeding

Caution

Dostabil AD 25 Tablet passes in very small amounts in breast milk. However, caution is advised while taking it. If you are breastfeeding, inform your doctor before taking this medicine.

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Driving

Unsafe

Do not drive vehicles or operate machines after taking Dostabil AD 25 Tablet as it can make you feel drowsy.

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Liver

Caution

Limited information is available on the use of Dostabil AD 25 Tablet in patients with liver disease. Hence, if you have liver problems, inform your doctor before taking this medicine.

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Kidney

Caution

Limited information is available on the use of Dostabil AD 25 Tablet in patients with kidney disease. Hence, if you have kidney problems, inform your doctor before taking this medicine.

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Children

Unsafe

Dostabil AD 25 Tablet is not recommended for use in children below 12 years.

Country of origin

INDIA
Other Info - DOS0054

Author Details

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FAQs

Dostabil AD 25 Tablet is used to treat depression. It is also used to treat disorders related to anxiety.
No, Dostabil AD 25 Tablet is not a muscle relaxant. It is a tricyclic antidepressant that is used for the treatment of depression and anxiety disorders.
Dostabil AD 25 Tablet starts to show its full effect in 4 to 6 weeks. Please consult your doctor if you feel that you are not feeling better or there is no improvement in the symptoms. In case you feel that you are experiencing any kind of side-effect after taking Dostabil AD 25 Tablet , please contact your doctor immediately.
Dostabil AD 25 Tablet contains ‘Dothiepin’ that works by increasing the levels of chemical messengers responsible for stabilizing and elevating the mood levels in the brain. It also stops your brain from releasing the chemicals which cause anxiety. Dostabil AD 25 Tablet helps improve your symptoms, such as elevating your mood and energy levels and improving sleep.
Based on your condition and symptoms, your doctor will advise the dose and duration of Dostabil AD 25 Tablet . Discuss with your doctor if you have any concerns.
Dostabil AD 25 Tablet is not recommended to treat pain. Rarely, it is advised to treat nerve pain like fibromyalgia or to prevent migraine.
No, Dostabil AD 25 Tablet is not a habit-forming substance. However, it can cause irritability and difficulty sleeping, especially if you stop taking it abruptly.
Dostabil AD 25 Tablet might cause weight gain as taking it makes you feel hungry. However, it varies from person to person, as some people might feel less hungry after taking it.
Always follow the instructions on the label or as directed by the physician for safe and effective use.
Both Dostabil AD 25 Tablet and amitriptyline belong to the tricyclic antidepressant class used to treat symptoms of depression. However, do not replace the Dostabil AD 25 Tablet with amitriptyline unless recommended by the doctor.
Dostabil AD 25 Tablet and doxepin belong to tricyclic antidepressant class medications used to treat symptoms of depression. However, they may have different mechanisms of action. However, do not replace the Dostabil AD 25 Tablet with doxepin unless recommended by the doctor.
You may take several weeks or longer to experience the full effect of Dostabil AD 25 Tablet . Even if you are feeling good, continue to take Dostabil AD 25 Tablet . Do not discontinue taking Dostabil AD 25 Tablet without consulting your doctor. Before quitting, your doctor will most likely recommend that you gradually reduce your dose
Dostabil AD 25 Tablet is associated with high mortality (death rate) in overdose. There is a low margin of safety between the maximum therapeutic dose and potentially fatal doses. So, you should strictly follow the dose and duration of Dostabil AD 25 Tablet as directed by the physician. Do not overdose at any cost. If you feel you or someone overdosed or experience any severe adverse events with Dostabil AD 25 Tablet , consult the doctor or go to the emergency room nearest hospital.
Caution should be exercised. The risk or severity of CNS depression can be increased when Diazepam is combined with Dostabil AD 25 Tablet .
No. Dostabil AD 25 Tablet is not intended to treat trigeminal neuralgia (sudden, severe facial pain. It's commonly described as a sudden shooting pain or as an electric shock to the jaw, teeth, or gums.).
No. $ name is not intended to treat burning mouth syndrome (a painful condition often described as a burning, scalding, or tingling feeling in the mouth that may occur every day for months).
Yes, Dostabil AD 25 Tablet is intended to treat depression. However, it is a prescription medication and should be taken only if the doctor prescribes it to you.
No. Dostabil AD 25 Tablet is not intended to treat IBS (irritable bowel syndrome). Dostabil AD 25 Tablet is a tricyclic antidepressant medication used to treat depression.
It is not intended for insomnia with depression alone. However, your doctor may suggest Dostabil AD 25 Tablet to treat insomnia with depression in some cases. Please consult your doctor for personalized guidance.
Dostabil AD 25 Tablet can change the way your nerves receive pain signals. This can help with some kinds of nerve pain, including fibromyalgia. However, it should only be taken as prescribed by the doctor.
Dostabil AD 25 Tablet is sometimes used to treat some types of nerve pain, such as fibromyalgia, or to prevent migraine. But it's not recommended or officially approved for pain relief.

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