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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 23, 2024 | 4:48 PM IST
Dothinx-25 Tablet 10's is used to treat depression and anxiety. It contains Dothiepin which works by increasing the levels of chemical messengers responsible for mood. In some cases, this medicine may cause side effects such as restlessness, irritability, tiredness, difficulty concentrating, and sleep disturbances. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Prescription drug

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Composition

DOTHIEPIN-25MG

Manufacturer/Marketer

Nuvenex Labs Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Dothinx-25 Tablet 10's

Dothinx-25 Tablet 10's belongs to the class of tricyclic antidepressants used to treat depression. It is primarily used to treat depression that is unresponsive to other antidepressants or any other alternative treatment. It is also used to treat disorders related to anxiety. Depression is a mood disorder that affects day to day life of a person. A person may have symptoms such as feeling sad or feeling lost and might have mood swings. Anxiety is defined as an emotion that is characterized by feelings of tension, worried thoughts and symptoms like increased blood pressure. Anxiety disorder also includes panic disorder which is characterized by sudden feelings of terror.

Dothinx-25 Tablet 10's contains ‘Dothiepin’ that works by increasing the levels of chemical messengers responsible for stabilizing and elevating the mood levels in the brain. It also stops your brain from releasing the chemicals which cause anxiety. It provides relief from symptoms such as feelings of restlessness, irritability, tiredness, difficulty concentrating, feeling and sleep disturbances. It helps to carry out daily activities easily.

Take this medicine as prescribed by your doctor. In some cases, you may experience side effects such as increased heart rate, blurred vision, dizziness, dryness in the mouth and constipation. Most of these side effects of Dothinx-25 Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

It is not recommended to take Dothinx-25 Tablet 10's if you are allergic to any contents of it. Do not stop taking this medicine without consulting your doctor, as it may lead to withdrawal symptoms. Do not take this medicine if you have any lung disease, muscle weakness (myasthenia gravis), sleeping disorder or difficulty in sleeping (sleep apnea), severe liver disease or problem with alcohol or other prescription recreational drugs. Inform your doctor if you are planning to get pregnant, are pregnant or breastfeeding. Dothinx-25 Tablet 10's is not recommended for use in children. In elderly people, Dothinx-25 Tablet 10's may require dose adjustments. Do not take alcohol while using Dothinx-25 Tablet 10's as it increases the risk of side effects. Dothinx-25 Tablet 10's may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.

Uses of Dothinx-25 Tablet 10's

Treatment of Depression, Anxiety.

Medicinal Benefits

Dothinx-25 Tablet 10's works by increasing the levels of chemical messengers that are responsible for stabilizing and elevating mood levels in the brain. It also stops your brain from releasing the chemicals which cause anxiety. Dothinx-25 Tablet 10's relieves symptoms such as restlessness, irritability, tiredness, difficulty concentrating and disturbances in sleep. It helps to carry out daily activities easily and improves the quality of life.

Directions for Use

Take this medicine as prescribed by your doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it. The dose and duration are given by the doctor based on your health condition.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Dothinx-25 Tablet 10's

  • Increased heart rate
  • Arrhythmias
  • Blurred vision
  • Dizziness
  • Dryness in the mouth
  • Weight gain
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Weight gain
  • Difficulty in urination
  • Constipation

Drug Warnings

Dothinx-25 Tablet 10's should be given with extreme caution in patients having epilepsy (brain disorder in which brain activity becomes abnormal, causing seizures), impaired liver or kidney function, diabetes, decreased level of sodium in the blood, tendency to develop bleedings or bruises easily, patients receiving electroconvulsive treatment, having coronary heart disease, suffering or have suffered from heart problems or have recently had a heart attack, having a low resting heart-rate, having prolonged severe diarrhoea and vomiting (being sick) or using diuretics (water tablets), experiencing a fast or irregular heartbeat, fainting, collapse or dizziness on standing up, which may indicate abnormal functioning of the heart rate and having or previously had eye problems, such as certain kinds of glaucoma (increased pressure in the eye).

Drug Interactions

Drug-Drug Interactions: This medicine may interact with other anti-depressants (phenelzine, iproniazid, isocarboxazid, nialamide, imipramine, desipramine, tranylcypromine and moclobemide), medicines used to treat Parkinson's disease (selegiline). Taking the above medicines with Dothinx-25 Tablet 10's can increase the risk of side effects. It can also have an interaction with an antibiotic (linezolid), a medicine used in the treatment of the manic-depressive disorder (lithium), a medicine used to treat migraines (sumatriptan), a medicine used for severe pain such (as tramadol), medicines used for stomach ulcers (cimetidine, lansoprazole and omeprazole), a medicine used to treat fungal infections (fluconazole), a medicine used to reduce the risk of stroke (ticlopidine), a herbal remedy used for depression (Hypericum perforatum), blood-thinning medicines (warfarin, dipyridamole and phenprocoumon), antimalarials (mefloquine), medicines used for heart diseases (flecainide and propafenone). Dothinx-25 Tablet 10's may also interact with medicines that decrease blood levels of potassium or magnesium, as these increase the risk of life-threatening heart rhythm disorder.

Drug-Food Interactions: No interactions found. 

Drug-Disease Interactions: People who are overweight or obese (with a BMI greater than 25) should consult a doctor before taking Dothinx-25 Tablet 10's.

Drug-Drug Interactions Checker List

  • PHENELZINE
  • ISOCARBOXAZID
  • IMIPRAMINE
  • DESIPRAMINE
  • TRANYLCYPROMINE
  • MOCLOBEMIDE
  • SELEGILINE
  • LINEZOLID
  • LITHIUM
  • SUMATRIPTAN
  • TRAMADOL
  • CIMETIDINE
  • LANSOPRAZOLE
  • OMEPRAZOLE
  • FLUCONAZOLE
  • TICLOPIDINE
  • HYPERICUM PERFORATUM
  • WARFARIN
  • DIPYRIDAMOLE
  • PHENPROCOUMON
  • MEFLOQUINE
  • FLECAINIDE
  • PROPAFENONE
  • IPRONIAZID
  • NIALAMIDE

Habit Forming

No

Diet & Lifestyle Advise

  • Opt for healthy food, which in turn will help you to elevate your moods.
  • Exercise daily for at least 30 minutes a day. It will help you to reduce stress and improve your mood. It will also improve your quality of sleep.
  • Take deep breaths to calm your mind.
  • Follow a consistent sleep schedule (at least 8 hours a day).
  • Manage your stress levels by doing activities that make you happy such as watching your favourite show, reading a book, listening to music and doing activities of your interest.

Special Advise

Do not stop taking Dothinx-25 Tablet 10's without consulting your doctor. You may experience side effects if you stop taking it suddenly. Your doctor will most likely advise you to gradually reduce your dose over several weeks before completely discontinuing it.

Disease/Condition Glossary

Depression: It is a mood disorder that has an impact on a person's daily life. Symptoms such as melancholy or loss, as well as mood changes, may occur.

Anxiety: It is characterised by tension, anxious thoughts, and symptoms such as elevated blood pressure. Panic disorder is a type of anxiety disorder marked by unexpected feelings of terror.

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Alcohol

Unsafe

Do not consume alcohol while taking Dothinx-25 Tablet 10's as it may cause serious side effects.

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Pregnancy

Unsafe

Dothinx-25 Tablet 10's is not recommended for use in pregnancy. If you are pregnant, please inform your doctor before taking this medicine.

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Breast Feeding

Caution

Dothinx-25 Tablet 10's passes in very small amounts in breast milk. However, caution is advised while taking it. If you are breastfeeding, inform your doctor before taking this medicine.

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Driving

Unsafe

Do not drive vehicles or operate machines after taking Dothinx-25 Tablet 10's as it can make you feel drowsy.

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Liver

Caution

Limited information is available on the use of Dothinx-25 Tablet 10's in patients with liver disease. Hence, if you have liver problems, inform your doctor before taking this medicine.

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Kidney

Caution

Limited information is available on the use of Dothinx-25 Tablet 10's in patients with kidney disease. Hence, if you have kidney problems, inform your doctor before taking this medicine.

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Children

Unsafe

Dothinx-25 Tablet 10's is not recommended for use in children below 12 years.

Country of origin

India

Manufacturer/Marketer address

Nuvenex Labs Pvt Ltd
Other Info - DOT0133

Author Details

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FAQs

Dothinx-25 Tablet 10's is used to treat depression. It is also used to treat disorders related to anxiety.
No, Dothinx-25 Tablet 10's is not a muscle relaxant. It is a tricyclic antidepressant that is used for the treatment of depression and anxiety disorders.
Dothinx-25 Tablet 10's starts to show its full effect in 4 to 6 weeks. Please consult your doctor if you feel that you are not feeling better or there is no improvement in the symptoms. In case you feel that you are experiencing any kind of side-effect after taking Dothinx-25 Tablet 10's, please contact your doctor immediately.
Dothinx-25 Tablet 10's contains ‘Dothiepin’ that works by increasing the levels of chemical messengers responsible for stabilizing and elevating the mood levels in the brain. It also stops your brain from releasing the chemicals which cause anxiety. Dothinx-25 Tablet 10's helps improve your symptoms, such as elevating your mood and energy levels and improving sleep.
Based on your condition and symptoms, your doctor will advise the dose and duration of Dothinx-25 Tablet 10's. Discuss with your doctor if you have any concerns.
Dothinx-25 Tablet 10's is not recommended to treat pain. Rarely, it is advised to treat nerve pain like fibromyalgia or to prevent migraine.
No, Dothinx-25 Tablet 10's is not a habit-forming substance. However, it can cause irritability and difficulty sleeping, especially if you stop taking it abruptly.
Dothinx-25 Tablet 10's might cause weight gain as taking it makes you feel hungry. However, it varies from person to person, as some people might feel less hungry after taking it.
Always follow the instructions on the label or as directed by the physician for safe and effective use.
Both Dothinx-25 Tablet 10's and amitriptyline belong to the tricyclic antidepressant class used to treat symptoms of depression. However, do not replace the Dothinx-25 Tablet 10's with amitriptyline unless recommended by the doctor.
Dothinx-25 Tablet 10's and doxepin belong to tricyclic antidepressant class medications used to treat symptoms of depression. However, they may have different mechanisms of action. However, do not replace the Dothinx-25 Tablet 10's with doxepin unless recommended by the doctor.
You may take several weeks or longer to experience the full effect of Dothinx-25 Tablet 10's. Even if you are feeling good, continue to take Dothinx-25 Tablet 10's. Do not discontinue taking Dothinx-25 Tablet 10's without consulting your doctor. Before quitting, your doctor will most likely recommend that you gradually reduce your dose
Dothinx-25 Tablet 10's is associated with high mortality (death rate) in overdose. There is a low margin of safety between the maximum therapeutic dose and potentially fatal doses. So, you should strictly follow the dose and duration of Dothinx-25 Tablet 10's as directed by the physician. Do not overdose at any cost. If you feel you or someone overdosed or experience any severe adverse events with Dothinx-25 Tablet 10's, consult the doctor or go to the emergency room nearest hospital.
Caution should be exercised. The risk or severity of CNS depression can be increased when Diazepam is combined with Dothinx-25 Tablet 10's.
No. Dothinx-25 Tablet 10's is not intended to treat trigeminal neuralgia (sudden, severe facial pain. It's commonly described as a sudden shooting pain or as an electric shock to the jaw, teeth, or gums.).
No. $ name is not intended to treat burning mouth syndrome (a painful condition often described as a burning, scalding, or tingling feeling in the mouth that may occur every day for months).
Yes, Dothinx-25 Tablet 10's is intended to treat depression. However, it is a prescription medication and should be taken only if the doctor prescribes it to you.
No. Dothinx-25 Tablet 10's is not intended to treat IBS (irritable bowel syndrome). Dothinx-25 Tablet 10's is a tricyclic antidepressant medication used to treat depression.
It is not intended for insomnia with depression alone. However, your doctor may suggest Dothinx-25 Tablet 10's to treat insomnia with depression in some cases. Please consult your doctor for personalized guidance.
Dothinx-25 Tablet 10's can change the way your nerves receive pain signals. This can help with some kinds of nerve pain, including fibromyalgia. However, it should only be taken as prescribed by the doctor.
Dothinx-25 Tablet 10's is sometimes used to treat some types of nerve pain, such as fibromyalgia, or to prevent migraine. But it's not recommended or officially approved for pain relief.

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