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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Cytosar 100 mg Injection 5 ml is an anticancer medicine used to treat leukemia (blood cancer). It contains Cytarabine, which belongs to the class of antimetabolites. It works by inhibiting the DNA polymerase enzyme responsible for DNA elongation, synthesis, and repair. In general, it inhibits the production of genetic material (DNA) in cancer cells, which is essential for cell growth, repair, and multiplication. Thus, It stops the multiplication of abnormal cells, leads to the development of cells in an unbalanced way and causes the death of cells.

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Whats That

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Composition :

CYTARABINE-100MG

Manufacturer/Marketer :

Pfizer Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Cytosar 100 mg Injection 5 ml

Cytosar 100 mg Injection 5 ml is an anticancer medicine used in the treatment of leukemia. Leukemia, also known as blood cancer, is a cancer of blood cells or blood-forming tissues. It causes excessive production of immature white blood cells by the bone marrow and reduces the body’s ability to fight infections. Cytosar 100 mg Injection 5 ml is used in the treatment of different types of leukemias, such as acute non-lymphocytic leukemia, acute lymphocytic leukemia, chronic myelocytic leukemia and meningeal leukemia.

Cytosar 100 mg Injection 5 ml contains Cytarabine, which belongs to the class of antimetabolites. It works by inhibiting the DNA polymerase enzyme responsible for DNA elongation, synthesis, and repair. In general, it inhibits the production of genetic material (DNA) in the cancer cells that are essential for the growth, repair and multiplication of cells. Thus, Cytosar 100 mg Injection 5 ml stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way and causes the death of cells.

Cytosar 100 mg Injection 5 ml may cause certain side effects such as vomiting, nausea, mouth ulcers, loss of appetite, diarrhea, dark-coloured urine, stomach pain, hair loss, dizziness, weakness, and pain at the site of injection, prescribed by your doctor. Most of these side effects of Cytosar 100 mg Injection 5 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please seek medical help. A trained healthcare professional will administer Cytosar 100 mg Injection 5 ml. Hence, do not self-administer.

If you are allergic to Cytosar 100 mg Injection 5 ml, inform your doctor and avoid taking it. Inform your doctor about your complete medical and medication history before starting treatment with Cytosar 100 mg Injection 5 ml. Cytosar 100 mg Injection 5 ml is contraindicated for pregnant women and breastfeeding women due to serious embryo-fetal toxicity. Hence, inform your doctor if you are pregnant, planning to become pregnant or breastfeeding. Inform your doctor if you have/had kidney or liver disease. Avoid alcohol consumption with Cytosar 100 mg Injection 5 ml as it may increase the risk of liver damage. Avoid excessive exposure to sunlight as Cytosar 100 mg Injection 5 ml may cause sensitivity to sunlight. You are advised to use sunscreen and wear protective clothing while going out.

Uses of Cytosar 100 mg Injection 5 ml

Treatment of Chronic myeloid leukemia, Acute lymphocytic leukemia, Acute non-lymphocytic leukemia, and meningeal leukemia

Directions for Use

Your oncology doctor will administer Cytosar 100 mg Injection 5 ml. Hence, do not self-administer.

Medicinal Benefits

Cytosar 100 mg Injection 5 ml contains Cytarabine, which belongs to the class of antimetabolites. It works by inhibiting the DNA polymerase enzyme that is responsible for DNA elongation, synthesis, and repair. In general, it inhibits the production of genetic material (DNA) in the cancer cells that are essential for cell growth, repair and multiplication. Thus, Cytosar 100 mg Injection 5 ml stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way and causes the death of cells.

How Cytosar 100 mg Injection 5 ml Works

Cytosar 100 mg Injection 5 ml contains Cytarabine, which belongs to the class of antimetabolites. It works by inhibiting the DNA polymerase enzyme responsible for DNA elongation, synthesis, and repair. In general, it inhibits the production of genetic material (DNA) in the cancer cells that are essential for the growth, repair and multiplication of cells. Thus, Cytosar 100 mg Injection 5 ml stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way and causes the death of cells.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Cytosar 100 mg Injection 5 ml

  • Vomiting
  • Nausea
  • Mouth ulcers
  • Loss of appetite
  • Diarrhoea
  • Dark-coloured urine
  • Dizziness
  • Confusion
  • Stomach pain
  • Weakness
  • Injection site reactions
  • Pain at the site of injection

What if I have taken an overdose of Cytosar 100 mg Injection 5 ml

Since Cytosar 100 mg Injection 5 ml is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly. Overdose of Cytosar 100 mg Injection 5 ml may cause confusion, mental/mood changes.

Drug Warnings

Cytosar 100 mg Injection 5 ml should be avoided if you are allergic to it or any other component present in it. Inform your doctor about your complete medical and medication history before starting treatment with Cytosar 100 mg Injection 5 ml. Cytosar 100 mg Injection 5 ml is contraindicated for pregnant women and breastfeeding women due to serious embryo-fetal toxicity. Hence, inform your doctor if you are pregnant, planning to become pregnant or breastfeeding. Inform your doctor if you have/had any pre-existing liver or kidney disease. Avoid taking Cytosar 100 mg Injection 5 ml if you are pregnant, as it may harm the foetus. Avoid alcohol consumption with Cytosar 100 mg Injection 5 ml as it may increase the risk of liver damage. Avoid excessive exposure to sunlight as Cytosar 100 mg Injection 5 ml may cause sensitivity to sunlight. You are advised to use sunscreen and wear protective clothing while going out. If you are about to receive any vaccinations, inform your doctor that you are taking Cytosar 100 mg Injection 5 ml as it may cause infection.

Drug-Drug Interactions

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CytarabineClozapine
Severe
CytarabineCladribine
Severe

Drug-Drug Interactions

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CytarabineClozapine
Severe
How does the drug interact with Cytosar 100 mg Injection 5 ml:
Combining Cytosar 100 mg Injection 5 ml with Clozapine can increase the risk of infection.

How to manage the interaction:
There may be a possibility of interaction between Cytosar 100 mg Injection 5 ml and Clozapine, but it can be taken if prescribed by a doctor. If you notice any of these symptoms - such as fever, sore throat, or muscle aches - contact your doctor immediately. Do not stop using any medications without talking to a doctor.
CytarabineCladribine
Severe
How does the drug interact with Cytosar 100 mg Injection 5 ml:
The combined use of cladribine with Cytosar 100 mg Injection 5 ml can increase the risk and severity of side effects.

How to manage the interaction:
Although taking Cytosar 100 mg Injection 5 ml and Cladribine together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms, it's important to contact your doctor right away. These symptoms include complications, infection, fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you pee. Do not stop using any medications without a doctor's advice.
CytarabineThalidomide
Severe
How does the drug interact with Cytosar 100 mg Injection 5 ml:
Taking thalidomide together with Cytosar 100 mg Injection 5 ml may increase the risk of blood clots.

How to manage the interaction:
Although taking thalidomide and Cytosar 100 mg Injection 5 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
CytarabineKetoconazole
Severe
How does the drug interact with Cytosar 100 mg Injection 5 ml:
Taking Cytosar 100 mg Injection 5 ml with Ketoconazole can increase the risk of liver damage.

How to manage the interaction:
Although there is a possible interaction between Cytosar 100 mg Injection 5 ml and Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, exhaustion, nausea, vomiting, dark urine, light stools, and skin or eye yellowing, decreased hunger, consult the doctor. Do not stop using any medications without talking to the doctor.
CytarabineBaricitinib
Severe
How does the drug interact with Cytosar 100 mg Injection 5 ml:
Coadministration of Cytosar 100 mg Injection 5 ml with Baricitinib can increase the risk of developing serious infections.

How to manage the interaction:
There may be a possibility of interaction between Cytosar 100 mg Injection 5 ml and Baricitinib, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
CytarabineEtanercept
Severe
How does the drug interact with Cytosar 100 mg Injection 5 ml:
When Etanercept is used with Cytosar 100 mg Injection 5 ml, the likelihood or severity of infection may increase.

How to manage the interaction:
Taking Cytosar 100 mg Injection 5 ml with Etanercept together can result in an interaction, but it can be taken if a doctor has advised it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
CytarabineInfliximab
Severe
How does the drug interact with Cytosar 100 mg Injection 5 ml:
Combining Infliximab with Cytosar 100 mg Injection 5 ml can increase the risk or severity of developing serious infections.

How to manage the interaction:
Co-administration of Cytosar 100 mg Injection 5 ml with Infliximab can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you pee, it's important to contact a doctor right away. Do not stop using any medications without talking to a doctor.
CytarabineTofacitinib
Severe
How does the drug interact with Cytosar 100 mg Injection 5 ml:
Taking Tofacitinib with Cytosar 100 mg Injection 5 ml may increase the risk of serious infection.

How to manage the interaction:
Taking Tofacitinib with Cytosar 100 mg Injection 5 ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a balanced diet including fruits and vegetables rich in nutrients and low-fat proteins like lean meats, fish and poultry.
  • Drink plenty of water daily while taking Cytosar 100 mg Injection 5 ml as some cancer therapies may cause dehydration.
  • Exercise regularly and maintain a healthy body weight.
  • Regularly wash your hands and avoid contact with people having infections.
  • Quit smoking.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Cytosar 100 mg Injection 5 ml Substitute

Substitutes safety advice
  • Biobin Injection 1 ml

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    131.40per tablet
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    46.35per tablet
  • CYTARINE 100MG INJECTION

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    82.92per tablet
  • Cytarine 100 mg Injection 1 ml

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    188.06per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol with Cytosar 100 mg Injection 5 ml as it may increase the risk of liver damage.

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Pregnancy

Unsafe

It is not recommended for use in pregnancy as it may harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Cytosar 100 mg Injection 5 ml. You should not become pregnant while on treatment with Cytosar 100 mg Injection 5 ml.

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Breast Feeding

Unsafe

It is not recommended for use in breastfeeding as it may pass into breast milk and harm your infant. If you are breastfeeding, inform your doctor before receiving Cytosar 100 mg Injection 5 ml. Your doctor may suggest you stop feeding while on treatment with this medicine.

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Driving

Unsafe

Cytosar 100 mg Injection 5 ml causes dizziness and may alter the ability to drive or operate machines. Hence, avoid driving or operating machines after receiving Cytosar 100 mg Injection 5 ml.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Cytosar 100 mg Injection 5 ml. It may lead to CNS toxicity in high doses.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before receiving Cytosar 100 mg Injection 5 ml as it may lead to kidney failure. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Cytosar 100 mg Injection 5 ml, combined with other approved anti-cancer medications, is suggested for inducing remission in adults and children with acute non-lymphocytic leukemia. Consult your doctor for more information.

FAQs

Cytosar 100 mg Injection 5 ml is used to treat Chronic myeloid leukemia, Acute lymphocytic leukemia, Acute non-lymphocytic leukemia, and meningeal leukemia.

Cytosar 100 mg Injection 5 ml contains Cytarabine, which belongs to the class of antimetabolites. It works by inhibiting the DNA polymerase enzyme that is responsible for DNA elongation, synthesis, and repair.

If you are about to receive any vaccinations, especially live vaccines such as measles, mumps, rubella and polio vaccines, it is advised to inform your doctor that you are on treatment with Cytosar 100 mg Injection 5 ml as it may cause infections.

Cytosar 100 mg Injection 5 ml may cause embryo-fetal toxicity. Therefore, please consult a doctor before taking Cytosar 100 mg Injection 5 ml if you are planning to become pregnant.

Cytosar 100 mg Injection 5 ml contains cytarabine as its active component. It is an anticancer medicine which belongs to the class of anti-metabolites.

Country of origin

India

Manufacturer/Marketer address

Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India
Other Info - CYT0029

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