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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

CYTARINE 100MG INJECTION is an anticancer medicine used to treat leukemia (blood cancer). It contains Cytarabine, which belongs to the class of antimetabolites. It works by inhibiting the DNA polymerase enzyme responsible for DNA elongation, synthesis, and repair. In general, it inhibits the production of genetic material (DNA) in cancer cells, which is essential for cell growth, repair, and multiplication. Thus, It stops the multiplication of abnormal cells, leads to the development of cells in an unbalanced way and causes the death of cells.

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Composition :

CYTARABINE-100MG

Manufacturer/Marketer :

Fresenius Kabi India Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About CYTARINE 100MG INJECTION

CYTARINE 100MG INJECTION is an anticancer medicine used in the treatment of leukemia. Leukemia, also known as blood cancer, is a cancer of blood cells or blood-forming tissues. It causes excessive production of immature white blood cells by the bone marrow and reduces the body’s ability to fight infections. CYTARINE 100MG INJECTION is used in the treatment of different types of leukemias, such as acute non-lymphocytic leukemia, acute lymphocytic leukemia, chronic myelocytic leukemia and meningeal leukemia.

CYTARINE 100MG INJECTION contains Cytarabine, which belongs to the class of antimetabolites. It works by inhibiting the DNA polymerase enzyme responsible for DNA elongation, synthesis, and repair. In general, it inhibits the production of genetic material (DNA) in the cancer cells that are essential for the growth, repair and multiplication of cells. Thus, CYTARINE 100MG INJECTION stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way and causes the death of cells.

CYTARINE 100MG INJECTION may cause certain side effects such as vomiting, nausea, mouth ulcers, loss of appetite, diarrhea, dark-coloured urine, stomach pain, hair loss, dizziness, weakness, and pain at the site of injection, prescribed by your doctor. Most of these side effects of CYTARINE 100MG INJECTION do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please seek medical help. A trained healthcare professional will administer CYTARINE 100MG INJECTION . Hence, do not self-administer.

If you are allergic to CYTARINE 100MG INJECTION , inform your doctor and avoid taking it. Inform your doctor about your complete medical and medication history before starting treatment with CYTARINE 100MG INJECTION . CYTARINE 100MG INJECTION is contraindicated for pregnant women and breastfeeding women due to serious embryo-fetal toxicity. Hence, inform your doctor if you are pregnant, planning to become pregnant or breastfeeding. Inform your doctor if you have/had kidney or liver disease. Avoid alcohol consumption with CYTARINE 100MG INJECTION as it may increase the risk of liver damage. Avoid excessive exposure to sunlight as CYTARINE 100MG INJECTION may cause sensitivity to sunlight. You are advised to use sunscreen and wear protective clothing while going out.

Uses of CYTARINE 100MG INJECTION

Treatment of Chronic myeloid leukemia, Acute lymphocytic leukemia, Acute non-lymphocytic leukemia, and meningeal leukemia

Directions for Use

Your oncology doctor will administer CYTARINE 100MG INJECTION . Hence, do not self-administer.

Medicinal Benefits

CYTARINE 100MG INJECTION contains Cytarabine, which belongs to the class of antimetabolites. It works by inhibiting the DNA polymerase enzyme that is responsible for DNA elongation, synthesis, and repair. In general, it inhibits the production of genetic material (DNA) in the cancer cells that are essential for cell growth, repair and multiplication. Thus, CYTARINE 100MG INJECTION stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way and causes the death of cells.

How CYTARINE 100MG INJECTION Works

CYTARINE 100MG INJECTION contains Cytarabine, which belongs to the class of antimetabolites. It works by inhibiting the DNA polymerase enzyme responsible for DNA elongation, synthesis, and repair. In general, it inhibits the production of genetic material (DNA) in the cancer cells that are essential for the growth, repair and multiplication of cells. Thus, CYTARINE 100MG INJECTION stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way and causes the death of cells.

Storage

Store in a cool and dry place away from sunlight

Side Effects of CYTARINE 100MG INJECTION

  • Vomiting
  • Nausea
  • Mouth ulcers
  • Loss of appetite
  • Diarrhoea
  • Dark-coloured urine
  • Dizziness
  • Confusion
  • Stomach pain
  • Weakness
  • Injection site reactions
  • Pain at the site of injection

What if I have taken an overdose of CYTARINE 100MG INJECTION

Since CYTARINE 100MG INJECTION is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly. Overdose of CYTARINE 100MG INJECTION may cause confusion, mental/mood changes.

Drug Warnings

CYTARINE 100MG INJECTION should be avoided if you are allergic to it or any other component present in it. Inform your doctor about your complete medical and medication history before starting treatment with CYTARINE 100MG INJECTION . CYTARINE 100MG INJECTION is contraindicated for pregnant women and breastfeeding women due to serious embryo-fetal toxicity. Hence, inform your doctor if you are pregnant, planning to become pregnant or breastfeeding. Inform your doctor if you have/had any pre-existing liver or kidney disease. Avoid taking CYTARINE 100MG INJECTION if you are pregnant, as it may harm the foetus. Avoid alcohol consumption with CYTARINE 100MG INJECTION as it may increase the risk of liver damage. Avoid excessive exposure to sunlight as CYTARINE 100MG INJECTION may cause sensitivity to sunlight. You are advised to use sunscreen and wear protective clothing while going out. If you are about to receive any vaccinations, inform your doctor that you are taking CYTARINE 100MG INJECTION as it may cause infection.

Drug-Drug Interactions

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CytarabineInfliximab
Severe
CytarabineCladribine
Severe

Drug-Drug Interactions

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CytarabineInfliximab
Severe
How does the drug interact with CYTARINE 100MG INJECTION :
Combining Infliximab with CYTARINE 100MG INJECTION can increase the risk or severity of developing serious infections.

How to manage the interaction:
Co-administration of CYTARINE 100MG INJECTION with Infliximab can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you pee, it's important to contact a doctor right away. Do not stop using any medications without talking to a doctor.
CytarabineCladribine
Severe
How does the drug interact with CYTARINE 100MG INJECTION :
The combined use of cladribine with CYTARINE 100MG INJECTION can increase the risk and severity of side effects.

How to manage the interaction:
Although taking CYTARINE 100MG INJECTION and Cladribine together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms, it's important to contact your doctor right away. These symptoms include complications, infection, fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you pee. Do not stop using any medications without a doctor's advice.
CytarabineThalidomide
Severe
How does the drug interact with CYTARINE 100MG INJECTION :
Taking thalidomide together with CYTARINE 100MG INJECTION may increase the risk of blood clots.

How to manage the interaction:
Although taking thalidomide and CYTARINE 100MG INJECTION together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
CytarabineTofacitinib
Severe
How does the drug interact with CYTARINE 100MG INJECTION :
Taking Tofacitinib with CYTARINE 100MG INJECTION may increase the risk of serious infection.

How to manage the interaction:
Taking Tofacitinib with CYTARINE 100MG INJECTION together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
CytarabineBaricitinib
Severe
How does the drug interact with CYTARINE 100MG INJECTION :
Coadministration of CYTARINE 100MG INJECTION with Baricitinib can increase the risk of developing serious infections.

How to manage the interaction:
There may be a possibility of interaction between CYTARINE 100MG INJECTION and Baricitinib, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
CytarabineClozapine
Severe
How does the drug interact with CYTARINE 100MG INJECTION :
Combining CYTARINE 100MG INJECTION with Clozapine can increase the risk of infection.

How to manage the interaction:
There may be a possibility of interaction between CYTARINE 100MG INJECTION and Clozapine, but it can be taken if prescribed by a doctor. If you notice any of these symptoms - such as fever, sore throat, or muscle aches - contact your doctor immediately. Do not stop using any medications without talking to a doctor.
CytarabineEtanercept
Severe
How does the drug interact with CYTARINE 100MG INJECTION :
When Etanercept is used with CYTARINE 100MG INJECTION , the likelihood or severity of infection may increase.

How to manage the interaction:
Taking CYTARINE 100MG INJECTION with Etanercept together can result in an interaction, but it can be taken if a doctor has advised it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
CytarabineKetoconazole
Severe
How does the drug interact with CYTARINE 100MG INJECTION :
Taking CYTARINE 100MG INJECTION with Ketoconazole can increase the risk of liver damage.

How to manage the interaction:
Although there is a possible interaction between CYTARINE 100MG INJECTION and Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, exhaustion, nausea, vomiting, dark urine, light stools, and skin or eye yellowing, decreased hunger, consult the doctor. Do not stop using any medications without talking to the doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a balanced diet including fruits and vegetables rich in nutrients and low-fat proteins like lean meats, fish and poultry.
  • Drink plenty of water daily while taking CYTARINE 100MG INJECTION as some cancer therapies may cause dehydration.
  • Exercise regularly and maintain a healthy body weight.
  • Regularly wash your hands and avoid contact with people having infections.
  • Quit smoking.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

CYTARINE 100MG INJECTION Substitute

Substitutes safety advice
  • Biobin Injection 1 ml

    60.30per tablet
  • Cytalon 100 mg Injection 1 ml

    131.40per tablet
  • Cytosar 100 mg Injection 5 ml

    25.78per tablet
  • Cytarine 100 mg Injection 1 ml

    188.06per tablet
  • Cytalon 500 Injection 5 ml

    101.26per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol with CYTARINE 100MG INJECTION as it may increase the risk of liver damage.

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Pregnancy

Unsafe

It is not recommended for use in pregnancy as it may harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving CYTARINE 100MG INJECTION . You should not become pregnant while on treatment with CYTARINE 100MG INJECTION .

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Breast Feeding

Unsafe

It is not recommended for use in breastfeeding as it may pass into breast milk and harm your infant. If you are breastfeeding, inform your doctor before receiving CYTARINE 100MG INJECTION . Your doctor may suggest you stop feeding while on treatment with this medicine.

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Driving

Unsafe

CYTARINE 100MG INJECTION causes dizziness and may alter the ability to drive or operate machines. Hence, avoid driving or operating machines after receiving CYTARINE 100MG INJECTION .

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before receiving CYTARINE 100MG INJECTION . It may lead to CNS toxicity in high doses.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before receiving CYTARINE 100MG INJECTION as it may lead to kidney failure. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

CYTARINE 100MG INJECTION , combined with other approved anti-cancer medications, is suggested for inducing remission in adults and children with acute non-lymphocytic leukemia. Consult your doctor for more information.

FAQs

CYTARINE 100MG INJECTION is used to treat Chronic myeloid leukemia, Acute lymphocytic leukemia, Acute non-lymphocytic leukemia, and meningeal leukemia.
CYTARINE 100MG INJECTION contains Cytarabine, which belongs to the class of antimetabolites. It works by inhibiting the DNA polymerase enzyme that is responsible for DNA elongation, synthesis, and repair.
If you are about to receive any vaccinations, especially live vaccines such as measles, mumps, rubella and polio vaccines, it is advised to inform your doctor that you are on treatment with CYTARINE 100MG INJECTION as it may cause infections.
CYTARINE 100MG INJECTION may cause embryo-fetal toxicity. Therefore, please consult a doctor before taking CYTARINE 100MG INJECTION if you are planning to become pregnant.
CYTARINE 100MG INJECTION contains cytarabine as its active component. It is an anticancer medicine which belongs to the class of anti-metabolites.
CYTARINE 100MG INJECTION is not considered a vesicant (irritant), but it should be administered carefully to prevent any potential issues.
No, ototoxicity (hearing damage) has not been reported with CYTARINE 100MG INJECTION use. However, if you experience any related symptoms, it is important to consult your doctor.
Yes, CYTARINE 100MG INJECTION is a cytotoxic (cell-damaging).
Yes, CYTARINE 100MG INJECTION may cause hair loss as this is one of its side effects. However, please, consult a doctor if this persists for longer durations.
CYTARINE 100MG INJECTION causes side effects such as nausea, vomiting, mouth ulcers, loss of appetite, diarrhoea, dark-coloured urine, confusion, dizziness, stomach pain, weakness, and injection site reactions. These will gradually reduce over time. However, consult a doctor if any of these persists longer.

Country of origin

INDIA

Manufacturer/Marketer address

Fresenius Kabi AG? , Else-Kröner-Straße 1 ? , 61352 Bad Homburg , Germany
Other Info - CYT0006

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