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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Capnea Injection 1 ml is used to treat apnea in premature newborns/neonates. By activating the respiratory centre and making it more sensitive to hypercapnia, this medication helps control the mean respiratory rate and tidal volume and enhances pulmonary blood flow. Common side effects include a fast heartbeat, irregular heartbeat, and hyperglycemia. It is a pediatric medication. Inform your doctor if your newborn is allergic to Capnea Injection 1 ml.
 

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Whats That

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Synonym :

CAFFEINE

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Capnea Injection 1 ml

Capnea Injection 1 ml belongs to a group of medicines known as methylxanthines. It is used to treat apnea of premature newborns. Apnea is a condition in which breathing is interrupted, causing abnormal heart rate and oxygen saturation changes. It is a common occurrence, particularly in premature infants.

Capnea Injection 1 ml contains 'Caffeine Citrate', which belongs to the central nervous system (CNS) stimulants class. This medicine stimulates the respiratory centre, sensitising it to hypercapnia. Thereby, Capnea Injection 1 ml effectively regulates the mean respiratory rate and tidal volume, improves pulmonary blood flow, and enhances the breathing pattern.

A paediatrician or healthcare professional will administer Capnea Injection 1 ml in a hospital setting. Capnea Injection 1 ml can cause side effects like a fast heartbeat, irregular heartbeat, and increased blood sugar levels. These side effects are not prevalent and vary from person to person. Consult your doctor if these symptoms continue or worsen.

Inform your doctor about the complete medical history of your infant. If you are nursing your infant and are being treated with this medication, avoid drinking coffee or using any other caffeine-containing products since caffeine passes into breast milk. This medication should be used with caution in infants with impaired hepatic or renal function. Before adjusting the dose, your doctor may assess your child's baseline serum caffeine levels if they were born to a mother who consumes caffeine.

Uses of Capnea Injection 1 ml

Capnea Injection 1 ml is commonly used to
1. Treat prematurity apnea:
Caffeine citrate is most commonly used to treat premature infants, particularly those born preterm. Premature babies, particularly those born before 28 weeks of gestation, may experience pauses in breathing lasting more than 20 seconds (apnea). This is known as apnea of prematurity, and caffeine citrate is used to stimulate the respiratory centre in the brain, hence improving breathing and decreasing apnea episodes.
2. Respiratory stimulation:
Capnea Injection 1 ml works as a central respiratory stimulant, which means it can be beneficial in instances when respiratory function is limited, particularly in preterm infants with underdeveloped respiratory systems.
3. Improvement of Diuresis:
Caffeine is a moderate diuretic, but this is not the primary reason for its usage in therapeutic settings.
4. Treatment for Neonatal Respiratory Depression:
Caffeine citrate may be utilised in newborns with respiratory depression, particularly when it is associated with disorders such as hypoxia or birth asphyxia.

Directions for Use

Capnea Injection 1 ml will be administered by a healthcare professional. Hence, do not self-administer to your newborn.

Medicinal Benefits

Capnea Injection 1 ml contains Caffeine Citrate as an active ingredient, which belongs to the central nervous system (CNS) stimulants class. By activating the respiratory centre and making it more sensitive to hypercapnia, this medication helps control the mean respiratory rate and tidal volume and enhances pulmonary blood flow.

How Capnea Injection 1 ml Works

Capnea Injection 1 ml contains Caffeine Citrate, which belongs to the central nervous system (CNS) stimulants class. It works in three different ways. This medicine stimulates the respiratory centre, sensitising it to hypercapnia. Thereby, Capnea Injection 1 ml effectively regulates the mean respiratory rate and tidal volume, improves pulmonary blood flow, and enhances the breathing pattern.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Capnea Injection 1 ml

  • Fast heartbeat
  • Increased blood sugar levels
  • Irregular heartbeat
  • Pain at the site of injection

What if I have taken an overdose of Capnea Injection 1 ml

Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include anxiety, stomach pain, irregular/fast heartbeat, seizures, and trouble sleeping. If your newborn experiences these symptoms or if you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Inform your doctor about your infant's medical history. If you are breastfeeding and your infant is being treated with this medication, avoid drinking coffee or using any other caffeine-containing products since caffeine passes into breast milk. Capnea Injection 1 ml should only be used in a neonatal intensive care unit where adequate patient surveillance and monitoring facilities are available. Treatment should begin under the supervision of a neonatologist with experience in neonatal intensive care. This medication should be used with caution in infants with impaired liver or kidney function.

Drug-Drug Interactions

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CaffeinePhenelzine
Critical
CaffeineTranylcypromine
Critical

Drug-Drug Interactions

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CaffeinePhenelzine
Critical
How does the drug interact with Capnea Injection 1 ml:
Taking these two together can cause your blood pressure to rise, a condition known as a hypertensive crisis.

How to manage the interaction:
Taking Capnea Injection 1 ml with Phenelzine is not recommended, please consult your doctor before taking it. They can be taken if your doctor advises it. Do not stop taking any medication without consulting your doctor.
CaffeineTranylcypromine
Critical
How does the drug interact with Capnea Injection 1 ml:
Coadministration of tranylcypromine with Capnea Injection 1 ml can in cause severe high blood pressure.

How to manage the interaction:
Taking Capnea Injection 1 ml with Tranylcypromine is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience headache, confusion, blurred vision, problems with speech or balance, nausea, vomiting, chest pain, convulsions, and sudden numbness or weakness (especially on one side of the body). Do not discontinue any medications without consulting a doctor.
CaffeineIsocarboxazid
Critical
How does the drug interact with Capnea Injection 1 ml:
Taking these two together can cause your blood pressure to rise, a condition known as a hypertensive crisis.

How to manage the interaction:
Taking Capnea Injection 1 ml with Isocarboxazid is not recommended, please consult your doctor before taking it. It can be taken if your doctor prescribes it. Do not stop taking any medication without consulting your doctor.
CaffeineLinezolid
Critical
How does the drug interact with Capnea Injection 1 ml:
Taking these two together can cause your blood pressure to rise, a condition known as a hypertensive crisis.

How to manage the interaction:
Taking Capnea Injection 1 ml with Linezolid is not recommended, please consult your doctor before taking it. It can be taken if your doctor prescribes it. Do not stop taking any medication without consulting your doctor.
CaffeineCocaine
Severe
How does the drug interact with Capnea Injection 1 ml:
Coadministration of Capnea Injection 1 ml with cocaine can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although there is an interaction, Capnea Injection 1 ml can be taken with cocaine if prescribed by the doctor. However, contact your doctor if you experience dizziness, lightheadedness, palpitations, and shortness of breath. Do not discontinue using any medication without contacting a doctor.
CaffeineEsketamine
Severe
How does the drug interact with Capnea Injection 1 ml:
Esketamine can cause increase in blood pressure and using it with Capnea Injection 1 ml may increase the risk.

How to manage the interaction:
Although there is a possible interaction between Capnea Injection 1 ml and Esketamine, it can be taken together if prescribed by your doctor. Do not discontinue using any medications without consulting your doctor.
CaffeineBupropion
Severe
How does the drug interact with Capnea Injection 1 ml:
Bupropion and Capnea Injection 1 ml can increase blood pressure. Concomitant use may have additive effects.

How to manage the interaction:
Although there is an interaction, Capnea Injection 1 ml can be taken with bupropion if prescribed by the doctor. Regular monitoring of blood pressure is advised.
CaffeineTizanidine
Severe
How does the drug interact with Capnea Injection 1 ml:
Coadministration of Capnea Injection 1 ml with Tizanidine may increase the blood levels and effects of tizanidine. This may cause excessive blood pressure, especially when rising from a sitting or lying position.

How to manage the interaction:
Although there is an interaction, Capnea Injection 1 ml can be taken with tizanidine if prescribed by the doctor. Contact your doctor if you experience dizziness, excessive sweating, or palpitations. Do not stop using any medicine without consulting your doctor.
CaffeineDipyridamole
Severe
How does the drug interact with Capnea Injection 1 ml:
Concomitant use of Capnea Injection 1 ml with dipyridamole may decrease the effects of dipyridamole.

How to manage the interaction:
Although there is an interaction, Capnea Injection 1 ml can be taken with dipyridamole if prescribed by the doctor. Avoiding Capnea Injection 1 ml for 12 to 24 hours before dipyridamole administration is advised.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

MISCELLANEOUS

Capnea Injection 1 ml Substitute

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Alcohol

Not applicable

-

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Pregnancy

Not applicable

-

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Breast Feeding

Caution

Capnea Injection 1 ml is intended for use in newborns/neonates only. If your infant is being treated with this medication, avoid drinking coffee or using any other caffeine-containing products since caffeine passes into breast milk.

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Driving

Not applicable

-

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Liver

Caution

Capnea Injection 1 ml should be used with caution in infants with impaired liver function.

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Kidney

Caution

Capnea Injection 1 ml should be used with caution in infants with impaired kidney function.

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Children

Consult your doctor

Capnea Injection 1 ml is intended for use in premature newborns and neonates. Consult your doctor for more information.

FAQs

Capnea Injection 1 ml is used in the treatment of apnea of premature newborns.

Capnea Injection 1 ml contains 'Caffeine Citrate', which belongs to the central nervous system (CNS) stimulants class. This medicine stimulates the respiratory center, sensitizing it to hypercapnia. Thereby Capnea Injection 1 ml effectively regulates the mean respiratory rate and tidal volume, improves pulmonary blood flow, and enhances the breathing pattern.

No, it is intended to treat apnea in premature newborns and neonates.

The dosage is determined by your babys weight, medical problems, and responsiveness to therapy. Before determining the dose, it is also necessary to establish the baseline serum caffeine levels in children born to caffeine-consuming mothers.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - CAP0093

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