apollo
0
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Jan 1, 2025 | 2:46 PM IST
Apnicaf Oral Solution 3 ml belongs to the class of methylxanthine drugs used in the treatment of primary apnea of premature newborns/neonates. This medicine helps regulate the mean respiratory rate and tidal volume, and improves pulmonary blood flow, by stimulating the respiratory centre, sensitising it to hypercapnia. Some of the common side effects include fast heartbeat, irregular heartbeat and hyperglycaemia. It is a paediatric medication and helps avoid using in adult population.
Read more
Prescription drug

Whats That

tooltip
Consult Doctor

Synonym :

CAFFEINE

Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Apnicaf Oral Solution 3 ml

Apnicaf Oral Solution 3 ml belongs to a group of medicines known as methylxanthines. It is used to treat primary apnoea of premature newborns (interrupted breathing in premature babies). Apnea is a condition where breathing interrupts and causes abnormal heart rate and oxygen saturation alterations. It is a common occurrence, particularly in premature infants.

Apnicaf Oral Solution 3 ml contains 'Caffeine Citrate', which belongs to the central nervous system (CNS) stimulants class. It works in three different ways. Firstly, it is the adenosine receptor antagonist; secondly, it is a phosphodiesterase inhibitor. And thirdly, it is an active intracellular calcium mobiliser. Collectively Caffeine stimulates the respiratory centre, sensitising it to hypercapnia. Thereby Apnicaf Oral Solution 3 ml effectively regulates the mean respiratory rate and tidal volume, improves pulmonary blood flow, decreases carbon dioxide sensitivity and enhances diaphragmatic function and breathing pattern.

Apnicaf Oral Solution 3 ml should be used as prescribed by your doctor. Your doctor will determine the suitable dosage based on your infant's medical conditions. In some cases, Apnicaf Oral Solution 3 ml can cause side effects like tachycardia (fast heartbeat), arrhythmia (irregular heartbeat) and hyperglycaemia (increased sugar in blood or serum). These side effects are not prevalent and vary from person to person. Consult your doctor if these symptoms continue or worsen. They may be able to recommend strategies to avoid or minimise certain side effects.

Inform your doctor about the complete medical history of your infant. If you are nursing your infant is being treated with this medication, avoid drinking coffee or using any other caffeine-containing products since Caffeine passes into breast milk. This medication should be used with caution in infants with impaired hepatic or renal function. Before fixing the dose, your doctor may assess baseline serum caffeine levels in children born to caffeine-consuming mothers.

Uses of Apnicaf Oral Solution 3 ml

Treatment of Primary apnea of premature newborns/neonates

Medicinal Benefits

Apnicaf Oral Solution 3 ml contains 'Caffeine Citrate', which belongs to the central nervous system (CNS) stimulants class. It works in three different ways. Firstly, it is the adenosine receptor antagonist; secondly, it is a phosphodiesterase inhibitor. And thirdly, it is an active intracellular calcium mobiliser. Collectively Caffeine stimulates the respiratory centre, sensitising it to hypercapnia. Thereby Apnicaf Oral Solution 3 ml effectively regulates the mean respiratory rate and tidal volume, improves pulmonary blood flow, decreases carbon dioxide sensitivity and enhances diaphragmatic function and breathing pattern.

Side Effects of Apnicaf Oral Solution 3 ml

  • Tachycardia (fast heartbeat)
  • Hyperglycaemia (increased sugar in blood or serum)
  • Arrhythmia (irregular heartbeat)

Directions for Use

Apnicaf Oral Solution 3 ml should be used as directed by your doctor.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Inform your doctor about your infant's medical history. If you are breastfeeding and your infant is being treated with this medication, avoid drinking coffee or using any other caffeine-containing products since caffeine passes into breast milk. Apnicaf Oral Solution 3 ml should only be used in a neonatal intensive care unit where adequate patient surveillance and monitoring facilities are available. Treatment should begin under the supervision of a neonatologist with experience in neonatal intensive care. This medication should be used with caution in infants with impaired liver or kidney function.

Therapeutic Class

ALTERNATIVE MEDICINE

Habit Forming

No

How Apnicaf Oral Solution 3 ml Works

Apnicaf Oral Solution 3 ml contains 'Caffeine Citrate', which belongs to the central nervous system (CNS) stimulants class. It works in three different ways. Firstly, it is the adenosine receptor antagonist; secondly, it is a phosphodiesterase inhibitor. And thirdly, it is an active intracellular calcium mobiliser. Collectively Caffeine stimulates the respiratory centre, sensitising it to hypercapnia. Thereby Apnicaf Oral Solution 3 ml effectively regulates the mean respiratory rate and tidal volume, improves pulmonary blood flow, decreases carbon dioxide sensitivity and enhances diaphragmatic function and breathing pattern.

What if I have taken an overdose of Apnicaf Oral Solution 3 ml

Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include anxiety, stomach pain, confusion, agitation, frequent urination, irregular/fast heartbeat, ringing in the ears, muscle twitching, seizures, and trouble sleeping. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.
bannner image

Alcohol

Caution

Apnicaf Oral Solution 3 ml is intended to use in premature newborns/neonates.

bannner image

Pregnancy

Caution

Apnicaf Oral Solution 3 ml is recommended to be used only in infants.

bannner image

Breast Feeding

Caution

Apnicaf Oral Solution 3 ml is intended for use in newborns/neonates only. If your infant is being treated with this medication, avoid drinking coffee or using any other caffeine-containing products since caffeine passes into breast milk.

bannner image

Driving

Caution

Apnicaf Oral Solution 3 ml is intended to use in premature newborns/neonates.

bannner image

Liver

Caution

Apnicaf Oral Solution 3 ml should be used with caution in infants with impaired hepatic or liver function.

bannner image

Kidney

Caution

Apnicaf Oral Solution 3 ml should be used with caution in infants with impaired renal or kidney function.

bannner image

Children

Caution

Apnicaf Oral Solution 3 ml is intended to use in premature newborns/neonates.

Country of origin

India

Manufacturer/Marketer address

16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India
Other Info - APN0015

Author Details

Doctor imageWe provide you with authentic, trustworthy and relevant information

Apnicaf Oral Solution 3 ml Substitute

Substitutes safety advice
  • Capnea Solution 1ml

    247.50per tablet
  • CAFIRATE SOLUTION 1.5ML

    371.30per tablet
  • Capnea Injection 1 ml

    252.50per tablet
  • Cafirate 20mg Injection 1ml

    by AYUR

    252.50per tablet
  • CAFIRATE 20MG INJECTION 3ML

    252.47per tablet

FAQs

Apnicaf Oral Solution 3 ml belongs to a group of medicines known as methylxanthines. It is used to treat primary apnoea of premature newborns (interrupted breathing in premature babies).
Apnicaf Oral Solution 3 ml contains 'Caffeine Citrate', which belongs to the central nervous system (CNS) stimulants class. It works in three different ways. Firstly, it is the adenosine receptor antagonist; secondly, it is a phosphodiesterase inhibitor. And thirdly, it is an active intracellular calcium mobiliser. Collectively Caffeine stimulates the respiratory centre, sensitising it to hypercapnia. Thereby Apnicaf Oral Solution 3 ml effectively regulates the mean respiratory rate and tidal volume, improves pulmonary blood flow, decreases carbon dioxide sensitivity and enhances diaphragmatic function and breathing pattern.
No, it is intended to treat primary apnoea of premature newborns/neonates.
The dosage is determined by your baby's weight, medical problems, and responsiveness to therapy. Before determining the dose, it is also necessary to establish the baseline serum caffeine levels in children born to caffeine-consuming mothers.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
whatsapp Floating Button