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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 30, 2024 | 5:51 AM IST

Basugine 100IU Injection is used to treat diabetes mellitus in adults, adolescents and children aged two years and above. It has a long and steady blood-sugar-lowering action. It helps to prevent complications from diabetes. It contains Insulin glargine, a long-acting insulin that works by ensuring consistent sugar control. Hence, it helps lower blood sugar levels throughout the day. Sometimes, you may experience side effects such as injection site reactions such as lumps under the skin. The injection site should be rotated to prevent skin changes such as lumps under the skin. You may also experience symptoms of hypoglycaemia (low blood sugar), such as sweating, clammy skin, anxiety, and a fast heartbeat.

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Manufacturer/Marketer

Lupin Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Apr-26

for this medicine

About Basugine 100IU Injection

Basugine 100IU Injection is a long-acting insulin that contains insulin glargine. Basugine 100IU Injection is used to treat diabetes mellitus in adults, adolescents and children aged two years and above. Diabetes mellitus is a disease where your body does not produce enough insulin to control the level of blood sugar. Basugine 100IU Injection has a long and steady blood-sugar-lowering action. Long-acting insulin takes about 2 hours to start acting and is designed to work uniformly so that there is no peak activity as such. The duration of long-acting insulin is up to 24 hours. Treatment with Basugine 100IU Injection helps to prevent complications from your diabetes. Do not use Basugine 100IU Injection to treat diabetic ketoacidosis (too much acid in the blood).

Basugine 100IU Injection is a long-acting insulin that works by ensuring consistent sugar control. Hence, it helps lower blood sugar levels throughout the day. Based on your lifestyle, the results of your blood sugar (glucose) tests, and your previous insulin usage. Your doctor will advise you how much Basugine 100IU Injection per day you will need and when you need to take it.

Sometimes, you may experience injection site reactions such as lumps under the skin. The injection site should be rotated to prevent skin changes such as lumps under the skin. You may also experience symptoms of hypoglycaemia (low blood sugar), such as sweating, clammy skin, anxiety, and a fast heartbeat. Most of these side effects of Basugine 100IU Injection do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking Basugine 100IU Injection of your own. Let your doctor know about this, as it may cause withdrawal symptoms. Do not take Basugine 100IU Injection if you have any low blood glucose levels, kidney, liver, or heart problems, or problems with alcohol or other prescription recreational drugs. Along with Basugine 100IU Injection, you should take a healthy diet, exercise regularly, and maintain weight as your doctor advises. Basugine 100IU Injection is a cold chain medicine, so it must be stored in the refrigerator between 2-8 degrees Celsius; otherwise, its efficiency might get lost. Do not store it in the freezer of the fridge.

Uses of Basugine 100IU Injection

Treatment of Diabetes (Type 1 diabetes mellitus, Type 2 diabetes mellitus)

Medicinal Benefits

Basugine 100IU Injection has a long and steady blood-sugar-lowering action. Long-acting insulin takes about 2 hours to start acting and is designed to work uniformly so that there is no peak activity as such. The duration of long-acting insulin is up to 24 hours. This insulin causes body tissues to absorb glucose from the blood and decreases glucose production by the liver. Basugine 100IU Injection helps in improving glycaemic control, which in turn reduces the risk of progression of complications of diabetes like damage to the retina (retinopathy), impairment of the kidney (nephropathy), injury of nerve cells (neuropathy), delayed wound healing, diabetic foot ulcer and others. Besides this, Basugine 100IU Injection can be safely prescribed to pregnant and lactating mothers.

Directions for Use

Basugine 100IU Injection is injected under the skin (subcutaneously). Do NOT inject Basugine 100IU Injection in a vein. You need one injection of Basugine 100IU Injection every day, at the same time of the day. If you are not well trained to self-administer Basugine 100IU Injection, ask healthcare professional to administer it.Procedure for self-injecting insulin:•You should wash your hands first before injecting insulin.•Then roll the insulin bottle and wipe the bottle top.•Now pull the plunger of the syringe down to an appropriate number of units your doctor has prescribed.•Push the needle into the bottle and push the syringe plunger down.•Now, once again, pull the plunger down to an appropriate number of units as prescribed by the doctor.•Pick the injection site and wipe it with an alcohol swab. Now, pinch up the skin, push the needle into the skin and then push the plunger in.•The needle should be kept under the skin for at least 6 seconds to make sure the entire dose is injected.•After injecting the insulin, pull out the needle and dispose of the syringe safely. And then you can have a meal or snack.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Basugine 100IU Injection

  • Low blood sugar or hypoglycaemia

  • Cold sweat

  • Cool pale skin

  • Nervousness

  • Anxious feeling

  • Unusual tiredness or weakness

  • Confusion

  • Difficulty in concentration

  • Drowsiness

  • Excessive hunger

  • Temporary vision changes

  • Headache

  • Nausea

  • Increased pulse or heartbeat (palpitation)

Drug Warnings

Basugine 100IU Injection is for subcutaneous (under the skin) use only and should never be administered intravenously (IV) or in the veins. If you are changing the brand of insulin or if you need to inject your insulin by another method, it should be done under strict medical supervision. Cases of heart failure were reported when pioglitazone was used with insulin, especially in patients at high risk of cardiac heart failure. The first symptoms of hyperglycaemia (high blood sugar level) may include symptoms like excessive thirst, dry mouth, increased frequency of urination, nausea, vomiting, drowsiness, flushed dry skin, loss of appetite and acetone odour of the breath. You should closely monitor these symptoms. Symptoms like heart failure, weight gain and oedema (fluid deposition in tissue) should not be overruled. It is advisable not to consume alcohol as it may increase or decrease your blood glucose level. Care should be taken while travelling across more than two time zones. Your doctor may adjust your insulin schedule. Basugine 100IU Injection may decrease the potassium level, leading to a state of hypokalaemia that, if left untreated, may lead to respiratory paralysis, irregular heartbeat rhythm, coma and even death. Do not take Basugine 100IU Injection if you have any low blood glucose levels, kidney, liver, or heart problems, or problems with alcohol or other prescription recreational drugs.

Drug Interactions

Drug-Drug Interactions: Basugine 100IU Injection may have an interaction with all other antidiabetic pills (sitagliptin), blood sugar enhancers (diazoxide), blood pressure-lowering pills (metoprolol, clonidine), antidepressants (lithium, fluoxetine), pain killers (aspirin, pentoxifylline, propoxyphene), anti TB drug (isoniazid), growth hormone (somatropin), thyroid hormone-related drugs (levothyroxine), antipsychotic medicines (phenothiazine, clozapine, olanzapine), anti-cholesterol drugs (fenofibrate), anti-asthmatic (epinephrine, salbutamol, terbutaline), female hormones like oestrogens and progestogens.

Drug-Food Interactions: Basugine 100IU Injection may interact with an ayurvedic, homoeopathy, Unani, herbal supplements or OTC items. Tell your doctor if you are using these products. Avoid drinking alcoholic beverages with Basugine 100IU Injection as it may raise or lower your blood sugar level.

Drug-Disease Interactions: Basugine 100IU Injection should not be given to patients with kidney disease, liver disease, low blood sugar/glucose level (hypoglycaemia), and low potassium level (hypokalaemia).

Drug-Drug Interactions Checker List

  • ASPIRIN
  • SITAGLIPTIN
  • PREGABALIN
  • METOPROLOL
  • LEVOTHYROXINE SODIUM
  • CLONIDINE
  • LITHIUM
  • FLUOXETINE
  • RIFAMPICIN+ISONIAZID
  • CLOZAPINE
  • OLANZAPINE
  • FENOFIBRATE
  • EPINEPHRINE
  • SALBUTAMOL
  • ESTROGEN
  • PROGESTERONE

Habit Forming

No

Diet & Lifestyle Advise

  • Exercise may lower your body’s need for insulin during and sometimes after physical activity.

  • Exercise may also speed up the effect of an insulin dose, especially if the activity involves the area of the injection site (for example, the leg should not be used for injection just before running).

  • Discuss with your doctor how to adjust your insulin regimen to accommodate exercise. 

  • Avoid eating sugar food and prefer food cooked food low in calories.

  • When travelling across more than two time zones, you should talk to your doctor concerning adjustments in your insulin schedule.

Special Advise

Change (rotate) your injection sites within the area you chose with each dose to reduce your risk of getting lipodystrophy (pitted or thickened skin) and localized cutaneous amyloidosis (skin with lumps) at the injection sites. Do not use the same spot for each injection or injection where the skin is pitted, thickened, lumpy, tender, bruised, scaly, hard, scarred or damaged.

Disease/Condition Glossary

Diabetes: Diabetes is a chronic or lifelong disease that prevents the body from utilizing insulin properly. Insulin is the hormone that controls sugar levels in the blood. Diabetes is a condition in which blood glucose levels are above normal. It is of two types: type-1 and type-2 diabetes. Type-1 diabetes is a condition in which the pancreas produces little or no insulin. Type-2 diabetes affects the way body processes the sugar. Symptoms of diabetes include lack of energy, tiredness, frequent urination, excess thirst, dry mouth, blurry vision, constant hunger, weight loss, and itchy skin.

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Alcohol

Unsafe

You are recommended not to consume alcohol along with Basugine 100IU Injection to avoid unpleasant side-effects. Alcohol may either decrease or increase the blood sugar level which can be fatal.

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Pregnancy

Safe if prescribed

Basugine 100IU Injection can be used during pregnancy. Your insulin dose may need to be changed during pregnancy and after delivery. Please consult your doctor before taking Basugine 100IU Injection.

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Breast Feeding

Safe if prescribed

Basugine 100IU Injection can be given safely to nursing mothers but only under the supervision of a physician. Physician may adjustments in your insulin doses and your diet.

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Driving

Caution

Drive with caution, Basugine 100IU Injection usually causes drowsiness and affects driving ability. Your ability to concentrate and react may be reduced if you have hypoglycaemia (low blood sugar).

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Liver

Caution

Basugine 100IU Injection to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Basugine 100IU Injection to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Safe if prescribed

Basugine 100IU Injection can be given safely to children provided; dose has to be prescribed by a child specialist.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India
Other Info - BAS0208

Author Details

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FAQs

Basugine 100IU Injection is used to treat diabetes mellitus in adults, adolescents and children aged two years and above.
Basugine 100IU Injection works by replacing the insulin that is normally produced by the body. It helps move sugar from the blood into other body tissues where it is used for energy. Basugine 100IU Injection also prevents the liver from producing more sugar.
The active substance is insulin glargine. Each ml of the solution contains 100 units of insulin glargine (equivalent to 3.64 mg).
Basugine 100IU Injection is a cold chain medicine which has to be stored 2-8 degree Celsius only else its efficiency of reducing blood glucose level declines. Do not keep inside the freezer.
Type-2 diabetes generally does not affect healthy children and teens, but it may affect children who are obese, which is also known as Childhood Obesity.
Cut back on foods high in sodium, alcohol, fried foods, and high-carb food and drinks like sugary drinks, drinks with added sugar, white rice and starchy vegetables.
Basugine 100IU Injection should not be discontinued without a doctor's consultation as stopping Basugine 100IU Injection may cause severe hypoglycaemia (low blood sugar) and ketoacidosis (buildup of acid in the blood). Consult the doctor if you feel uncomfortable after taking Basugine 100IU Injection.
The injection site should be changed to prevent skin changes like lumps under the skin. Basugine 100IU Injection may not work well if injected into the lumpy area.
Maintain a healthy diet and exercise regularly. Limit sugar intake and avoid smoking & alcohol consumption. Manage stress by doing meditation or yoga.
Hypoglycaemia (low blood sugar) may occur because you inject too much insulin, miss or delay meals, do not eat enough, eat food containing less carbohydrate than normal, drink alcohol, lose carbohydrates due to vomiting or diarrhoea, do more exercise than usual or a different type of physical activity, are recovering from an injury, illness, operation or stress, or are taking/have stopped taking other medicines.
Basugine 100IU Injection contains insulin glargine, a modified insulin which is very similar to human insulin.
Check the label for directions and use Basugine 100IU Injection as advised by the doctor. Talk to the doctor if you have any concerns. Fill the injection with the appropriate dose. Pick the injection site and wipe it with an alcohol swab. Now, pinch up the skin, inject the needle into the skin and then push the plunger in. After injecting the insulin, pull out the needle and dispose of the syringe safely.
Basugine 100IU Injection should be used only as prescribed by the doctor. The doctor will recommend the dose and duration based on your condition.
Using more than the prescribed dose of Basugine 100IU Injection may cause hypoglycaemia (low blood sugar). Monitor blood glucose levels and consult the doctor if the blood sugar levels are low.
The dose of Basugine 100IU Injection may need to be changed based on your blood sugar levels, lifestyle conditions, if are taking certain other medicines, during pregnancy, after giving birth, and breastfeeding.
Serious side effects of Basugine 100IU Injection include severe allergic reactions (rash/itching all over the body, severe swelling of skin or mucous membrane, shortness of breath, a fall in blood pressure with rapid heartbeat and sweating) and hypoglycaemia (thirst, tiredness, increased urge to urinate, tiredness, fast heartbeat, and low blood pressure). Seek immediate medical attention if you experience these symptoms.
Basugine 100IU Injection can be given to treat both the condition of type 1 and type 2 diabetes mellitus. However, your doctor will decide whether Basugine 100IU Injection can be given to you or not depending on your present condition. Basugine 100IU Injection should be avoided in patients who are allergic to Basugine 100IU Injection or other forms of insulin. It should be avoided in patients suffering from low potassium level (hypokalemia), moderate to severe kidney disease or liver disease. Inform the doctor if you are pregnant or breastfeeding.

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Keep Refrigerated. Do not freeze.