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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Xglar Refil 100Iu/Ml Cartridge 3 ml is used to treat diabetes mellitus in adults, adolescents and children aged two years and above. It has a long and steady blood-sugar-lowering action. It helps to prevent complications from diabetes. It contains Insulin glargine, a long-acting insulin that works by ensuring consistent sugar control. Hence, it helps lower blood sugar levels throughout the day. Sometimes, you may experience side effects such as injection site reactions such as lumps under the skin. The injection site should be rotated to prevent skin changes such as lumps under the skin. You may also experience symptoms of hypoglycaemia (low blood sugar), such as sweating, clammy skin, anxiety, and a fast heartbeat.

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Prescription drug

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Manufacturer/Marketer :

Eris Life Sciences Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

Xglar Refil 100Iu/Ml Cartridge 3 ml is a long-acting insulin that contains insulin glargine. Xglar Refil 100Iu/Ml Cartridge 3 ml is used to treat diabetes mellitus in adults, adolescents and children aged two years and above. Diabetes mellitus is a disease where your body does not produce enough insulin to control the level of blood sugar. Xglar Refil 100Iu/Ml Cartridge 3 ml has a long and steady blood-sugar-lowering action. Long-acting insulin takes about 2 hours to start acting and is designed to work uniformly so that there is no peak activity as such. The duration of long-acting insulin is up to 24 hours. Treatment with Xglar Refil 100Iu/Ml Cartridge 3 ml helps to prevent complications from your diabetes. Do not use Xglar Refil 100Iu/Ml Cartridge 3 ml to treat diabetic ketoacidosis (too much acid in the blood).

Xglar Refil 100Iu/Ml Cartridge 3 ml is a long-acting insulin that works by ensuring consistent sugar control. Hence, it helps lower blood sugar levels throughout the day. Based on your lifestyle, the results of your blood sugar (glucose) tests, and your previous insulin usage. Your doctor will advise you how much Xglar Refil 100Iu/Ml Cartridge 3 ml per day you will need and when you need to take it.

Sometimes, you may experience injection site reactions such as lumps under the skin. The injection site should be rotated to prevent skin changes such as lumps under the skin. You may also experience symptoms of hypoglycaemia (low blood sugar), such as sweating, clammy skin, anxiety, and a fast heartbeat. Most of these side effects of Xglar Refil 100Iu/Ml Cartridge 3 ml do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking Xglar Refil 100Iu/Ml Cartridge 3 ml of your own. Let your doctor know about this, as it may cause withdrawal symptoms. Do not take Xglar Refil 100Iu/Ml Cartridge 3 ml if you have any low blood glucose levels, kidney, liver, or heart problems, or problems with alcohol or other prescription recreational drugs. Along with Xglar Refil 100Iu/Ml Cartridge 3 ml, you should take a healthy diet, exercise regularly, and maintain weight as your doctor advises. Xglar Refil 100Iu/Ml Cartridge 3 ml is a cold chain medicine, so it must be stored in the refrigerator between 2-8 degrees Celsius; otherwise, its efficiency might get lost. Do not store it in the freezer of the fridge.

Treatment of Diabetes (Type 1 diabetes mellitus, Type 2 diabetes mellitus)
Xglar Refil 100Iu/Ml Cartridge 3 ml is injected under the skin (subcutaneously). Do NOT inject Xglar Refil 100Iu/Ml Cartridge 3 ml in a vein. You need one injection of Xglar Refil 100Iu/Ml Cartridge 3 ml every day, at the same time of the day. If you are not well trained to self-administer Xglar Refil 100Iu/Ml Cartridge 3 ml, ask healthcare professional to administer it.Procedure for self-injecting insulin:•You should wash your hands first before injecting insulin.•Then roll the insulin bottle and wipe the bottle top.•Now pull the plunger of the syringe down to an appropriate number of units your doctor has prescribed.•Push the needle into the bottle and push the syringe plunger down.•Now, once again, pull the plunger down to an appropriate number of units as prescribed by the doctor.•Pick the injection site and wipe it with an alcohol swab. Now, pinch up the skin, push the needle into the skin and then push the plunger in.•The needle should be kept under the skin for at least 6 seconds to make sure the entire dose is injected.•After injecting the insulin, pull out the needle and dispose of the syringe safely. And then you can have a meal or snack.

Xglar Refil 100Iu/Ml Cartridge 3 ml has a long and steady blood-sugar-lowering action. Long-acting insulin takes about 2 hours to start acting and is designed to work uniformly so that there is no peak activity as such. The duration of long-acting insulin is up to 24 hours. This insulin causes body tissues to absorb glucose from the blood and decreases glucose production by the liver. Xglar Refil 100Iu/Ml Cartridge 3 ml helps in improving glycaemic control, which in turn reduces the risk of progression of complications of diabetes like damage to the retina (retinopathy), impairment of the kidney (nephropathy), injury of nerve cells (neuropathy), delayed wound healing, diabetic foot ulcer and others. Besides this, Xglar Refil 100Iu/Ml Cartridge 3 ml can be safely prescribed to pregnant and lactating mothers.

Xglar Refil 100Iu/Ml Cartridge 3 ml is a long-acting insulin that works by ensuring consistent sugar control. Hence, it helps lower blood sugar levels throughout the day. Based on your lifestyle, the results of your blood sugar (glucose) tests, and your previous insulin usage.
Store in a cool and dry place away from sunlight
  • Low blood sugar or hypoglycaemia

  • Cold sweat

  • Cool pale skin

  • Nervousness

  • Anxious feeling

  • Unusual tiredness or weakness

  • Confusion

  • Difficulty in concentration

  • Drowsiness

  • Excessive hunger

  • Temporary vision changes

  • Headache

  • Nausea

  • Increased pulse or heartbeat (palpitation)

Do not take more than the prescribed dose of Xglar Refil 100Iu/Ml Cartridge 3 ml as it may cause overdose and lead to low blood sugar. If you suspect you have taken overdose or have symptoms of low blood sugar or other symptoms such as seizures (fits) or loss of consciousness, please consult a doctor immediately.

Xglar Refil 100Iu/Ml Cartridge 3 ml is for subcutaneous (under the skin) use only and should never be administered intravenously (IV) or in the veins. If you are changing the brand of insulin or if you need to inject your insulin by another method, it should be done under strict medical supervision. Cases of heart failure were reported when pioglitazone was used with insulin, especially in patients at high risk of cardiac heart failure. The first symptoms of hyperglycaemia (high blood sugar level) may include symptoms like excessive thirst, dry mouth, increased frequency of urination, nausea, vomiting, drowsiness, flushed dry skin, loss of appetite and acetone odour of the breath. You should closely monitor these symptoms. Symptoms like heart failure, weight gain and oedema (fluid deposition in tissue) should not be overruled. It is advisable not to consume alcohol as it may increase or decrease your blood glucose level. Care should be taken while travelling across more than two time zones. Your doctor may adjust your insulin schedule. Xglar Refil 100Iu/Ml Cartridge 3 ml may decrease the potassium level, leading to a state of hypokalaemia that, if left untreated, may lead to respiratory paralysis, irregular heartbeat rhythm, coma and even death. Do not take Xglar Refil 100Iu/Ml Cartridge 3 ml if you have any low blood glucose levels, kidney, liver, or heart problems, or problems with alcohol or other prescription recreational drugs.

verifiedApollotooltip
Insulin glargineLevofloxacin
Severe
Insulin glargineGrepafloxacin
Severe

Drug-Drug Interactions

Insulin glargineLevofloxacin
Severe
How does the drug interact with Xglar Refil 100Iu/Ml Cartridge 3 ml:
Blood glucose levels can be affected by levofloxacin when taken with Xglar Refil 100Iu/Ml Cartridge 3 ml. It may cause hyperglycemia (high blood glucose) and, less commonly, hypoglycemia (low blood glucose).

How to manage the interaction:
There could be a possible interaction between Xglar Refil 100Iu/Ml Cartridge 3 ml and Levofloxacin but can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms of hypoglycemia, which include headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat, or symptoms of hyperglycemia which may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without talking to a doctor.
Insulin glargineGrepafloxacin
Severe
How does the drug interact with Xglar Refil 100Iu/Ml Cartridge 3 ml:
Taking Xglar Refil 100Iu/Ml Cartridge 3 ml with grepafloxacin affects blood glucose levels, which may cause hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar) less frequently.

How to manage the interaction:
Although taking Grepafloxacin and Xglar Refil 100Iu/Ml Cartridge 3 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, shaking, nausea, hunger, weakness, sweating, palpitation, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without talking to a doctor.
Insulin glargineGatifloxacin
Severe
How does the drug interact with Xglar Refil 100Iu/Ml Cartridge 3 ml:
Taking Xglar Refil 100Iu/Ml Cartridge 3 ml with gatifloxacin affects blood glucose levels, which may cause hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar) less frequently.

How to manage the interaction:
Although taking Gatifloxacin and Xglar Refil 100Iu/Ml Cartridge 3 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, shaking, nausea, hunger, weakness, sweating, palpitation, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without first talking to your doctor.
Insulin glargineNorfloxacin
Severe
How does the drug interact with Xglar Refil 100Iu/Ml Cartridge 3 ml:
Taking Xglar Refil 100Iu/Ml Cartridge 3 ml with Norfloxacin affects blood glucose levels, which may cause hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar) less frequently.

How to manage the interaction:
Although taking Norfloxacin and Xglar Refil 100Iu/Ml Cartridge 3 ml together can result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, tremors, nausea, loss of hunger, weakness, sweating, palpitation, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without talking to a doctor.
Insulin glargineMoxifloxacin
Severe
How does the drug interact with Xglar Refil 100Iu/Ml Cartridge 3 ml:
Taking Xglar Refil 100Iu/Ml Cartridge 3 ml with Moxifloxacin affects blood glucose levels, which may cause hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar) less frequently.

How to manage the interaction:
Although taking Moxifloxacin and Xglar Refil 100Iu/Ml Cartridge 3 ml together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience headache, dizziness, and rapid heartbeat, increased thirst, and increased urination. Do not stop using any medications without talking to a doctor.
Insulin glargineCiprofloxacin
Severe
How does the drug interact with Xglar Refil 100Iu/Ml Cartridge 3 ml:
Taking Xglar Refil 100Iu/Ml Cartridge 3 ml with ciprofloxacin can effect blood sugar levels, both hyperglycemia (high blood sugar) and, less frequently, hypoglycemia (low blood sugar).

How to manage the interaction:
Although taking ciprofloxacin and Xglar Refil 100Iu/Ml Cartridge 3 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult a doctor if you experience hypoglycemia, hyperglycemia, or a decline in blood glucose control. Hypoglycemia can cause headaches, dizziness, sleepiness, anxiety, confusion, shaking, nausea, hunger, weakness, sweating, palpitations, and a rapid heartbeat. Increased hunger, thirst, and urine are all possible signs of hyperglycemia. It is recommended to maintain blood glucose levels.
Insulin glargineGemifloxacin
Severe
How does the drug interact with Xglar Refil 100Iu/Ml Cartridge 3 ml:
Taking Xglar Refil 100Iu/Ml Cartridge 3 ml with Gemifloxacin affects blood glucose levels, which may cause hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar) less frequently.

How to manage the interaction:
Although taking Gemifloxacin and Xglar Refil 100Iu/Ml Cartridge 3 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, shaking, nausea, hunger, weakness, sweating, palpitation, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without first talking to your doctor.
Insulin glargineLomefloxacin
Severe
How does the drug interact with Xglar Refil 100Iu/Ml Cartridge 3 ml:
Taking Xglar Refil 100Iu/Ml Cartridge 3 ml with lomefloxacin affects blood glucose levels, which may cause hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar) less frequently.

How to manage the interaction:
Although taking Lomefloxacin and Xglar Refil 100Iu/Ml Cartridge 3 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, shaking, nausea, loss of hunger, weakness, sweating, palpitation, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without talking to a doctor.
Insulin glargineSparfloxacin
Severe
How does the drug interact with Xglar Refil 100Iu/Ml Cartridge 3 ml:
Taking Xglar Refil 100Iu/Ml Cartridge 3 ml with sparfloxacin affects blood glucose levels, which may cause hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar) less frequently.

How to manage the interaction:
Although taking Sparfloxacin and Xglar Refil 100Iu/Ml Cartridge 3 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, shaking, nausea, hunger, weakness, sweating, palpitations, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without first talking to your doctor.
Insulin glargineNalidixic acid
Severe
How does the drug interact with Xglar Refil 100Iu/Ml Cartridge 3 ml:
Taking Xglar Refil 100Iu/Ml Cartridge 3 ml with nalidixic acid affects blood glucose levels, which may cause hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar) less frequently.

How to manage the interaction:
Although taking nalidixic acid and Xglar Refil 100Iu/Ml Cartridge 3 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, shaking, nausea, loss of hunger, weakness, sweating, palpitation, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without first talking to your doctor.
verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

  • Exercise may lower your body’s need for insulin during and sometimes after physical activity.

  • Exercise may also speed up the effect of an insulin dose, especially if the activity involves the area of the injection site (for example, the leg should not be used for injection just before running).

  • Discuss with your doctor how to adjust your insulin regimen to accommodate exercise. 

  • Avoid eating sugar food and prefer food cooked food low in calories.

  • When travelling across more than two time zones, you should talk to your doctor concerning adjustments in your insulin schedule.

No
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Unsafe

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Safe if prescribed

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Safe if prescribed

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Caution

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Caution

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Caution

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Safe if prescribed

FAQs

Xglar Refil 100Iu/Ml Cartridge 3 ml is used to treat diabetes mellitus in adults, adolescents and children aged two years and above.
Xglar Refil 100Iu/Ml Cartridge 3 ml works by replacing the insulin that is normally produced by the body. It helps move sugar from the blood into other body tissues where it is used for energy. Xglar Refil 100Iu/Ml Cartridge 3 ml also prevents the liver from producing more sugar.
The active substance is insulin glargine. Each ml of the solution contains 100 units of insulin glargine (equivalent to 3.64 mg).
Xglar Refil 100Iu/Ml Cartridge 3 ml is a cold chain medicine which has to be stored 2-8 degree Celsius only else its efficiency of reducing blood glucose level declines. Do not keep inside the freezer.
Type-2 diabetes generally does not affect healthy children and teens, but it may affect children who are obese, which is also known as Childhood Obesity.
Cut back on foods high in sodium, alcohol, fried foods, and high-carb food and drinks like sugary drinks, drinks with added sugar, white rice and starchy vegetables.
Xglar Refil 100Iu/Ml Cartridge 3 ml should not be discontinued without a doctor's consultation as stopping Xglar Refil 100Iu/Ml Cartridge 3 ml may cause severe hypoglycaemia (low blood sugar) and ketoacidosis (buildup of acid in the blood). Consult the doctor if you feel uncomfortable after taking Xglar Refil 100Iu/Ml Cartridge 3 ml.
The injection site should be changed to prevent skin changes like lumps under the skin. Xglar Refil 100Iu/Ml Cartridge 3 ml may not work well if injected into the lumpy area.
Maintain a healthy diet and exercise regularly. Limit sugar intake and avoid smoking & alcohol consumption. Manage stress by doing meditation or yoga.
Hypoglycaemia (low blood sugar) may occur because you inject too much insulin, miss or delay meals, do not eat enough, eat food containing less carbohydrate than normal, drink alcohol, lose carbohydrates due to vomiting or diarrhoea, do more exercise than usual or a different type of physical activity, are recovering from an injury, illness, operation or stress, or are taking/have stopped taking other medicines.
Xglar Refil 100Iu/Ml Cartridge 3 ml contains insulin glargine, a modified insulin which is very similar to human insulin.
Check the label for directions and use Xglar Refil 100Iu/Ml Cartridge 3 ml as advised by the doctor. Talk to the doctor if you have any concerns. Fill the injection with the appropriate dose. Pick the injection site and wipe it with an alcohol swab. Now, pinch up the skin, inject the needle into the skin and then push the plunger in. After injecting the insulin, pull out the needle and dispose of the syringe safely.
Xglar Refil 100Iu/Ml Cartridge 3 ml should be used only as prescribed by the doctor. The doctor will recommend the dose and duration based on your condition.
Using more than the prescribed dose of Xglar Refil 100Iu/Ml Cartridge 3 ml may cause hypoglycaemia (low blood sugar). Monitor blood glucose levels and consult the doctor if the blood sugar levels are low.
The dose of Xglar Refil 100Iu/Ml Cartridge 3 ml may need to be changed based on your blood sugar levels, lifestyle conditions, if are taking certain other medicines, during pregnancy, after giving birth, and breastfeeding.
Serious side effects of Xglar Refil 100Iu/Ml Cartridge 3 ml include severe allergic reactions (rash/itching all over the body, severe swelling of skin or mucous membrane, shortness of breath, a fall in blood pressure with rapid heartbeat and sweating) and hypoglycaemia (thirst, tiredness, increased urge to urinate, tiredness, fast heartbeat, and low blood pressure). Seek immediate medical attention if you experience these symptoms.
Xglar Refil 100Iu/Ml Cartridge 3 ml can be given to treat both the condition of type 1 and type 2 diabetes mellitus. However, your doctor will decide whether Xglar Refil 100Iu/Ml Cartridge 3 ml can be given to you or not depending on your present condition. Xglar Refil 100Iu/Ml Cartridge 3 ml should be avoided in patients who are allergic to Xglar Refil 100Iu/Ml Cartridge 3 ml or other forms of insulin. It should be avoided in patients suffering from low potassium level (hypokalemia), moderate to severe kidney disease or liver disease. Inform the doctor if you are pregnant or breastfeeding.
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Other Info - XGL0007

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