Nobeglar-Uno 100IU Prefilled Pen 3 ml is a long-acting insulin that contains insulin glargine. Nobeglar-Uno 100IU Prefilled Pen 3 ml is used to treat diabetes mellitus in adults, adolescents and children aged two years and above. Diabetes mellitus is a disease where your body does not produce enough insulin to control the level of blood sugar. Nobeglar-Uno 100IU Prefilled Pen 3 ml has a long and steady blood-sugar-lowering action. Long-acting insulin takes about 2 hours to start acting and is designed to work uniformly so that there is no peak activity as such. The duration of long-acting insulin is up to 24 hours. Treatment with Nobeglar-Uno 100IU Prefilled Pen 3 ml helps to prevent complications from your diabetes. Do not use Nobeglar-Uno 100IU Prefilled Pen 3 ml to treat diabetic ketoacidosis (too much acid in the blood).

Nobeglar-Uno 100IU Prefilled Pen 3 ml is a long-acting insulin that works by ensuring consistent sugar control. Hence, it helps lower blood sugar levels throughout the day. Based on your lifestyle, the results of your blood sugar (glucose) tests, and your previous insulin usage. Your doctor will advise you how much Nobeglar-Uno 100IU Prefilled Pen 3 ml per day you will need and when you need to take it.

Sometimes, you may experience injection site reactions such as lumps under the skin. The injection site should be rotated to prevent skin changes such as lumps under the skin. You may also experience symptoms of hypoglycaemia (low blood sugar), such as sweating, clammy skin, anxiety, and a fast heartbeat. Most of these side effects of Nobeglar-Uno 100IU Prefilled Pen 3 ml do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking Nobeglar-Uno 100IU Prefilled Pen 3 ml of your own. Let your doctor know about this, as it may cause withdrawal symptoms. Do not take Nobeglar-Uno 100IU Prefilled Pen 3 ml if you have any low blood glucose levels, kidney, liver, or heart problems, or problems with alcohol or other prescription recreational drugs. Along with Nobeglar-Uno 100IU Prefilled Pen 3 ml, you should take a healthy diet, exercise regularly, and maintain weight as your doctor advises. Nobeglar-Uno 100IU Prefilled Pen 3 ml is a cold chain medicine, so it must be stored in the refrigerator between 2-8 degrees Celsius; otherwise, its efficiency might get lost. Do not store it in the freezer of the fridge.

Nobeglar-Uno 100IU Prefilled Pen 3 ml has a long and steady blood-sugar-lowering action. Long-acting insulin takes about 2 hours to start acting and is designed to work uniformly so that there is no peak activity as such. The duration of long-acting insulin is up to 24 hours. This insulin causes body tissues to absorb glucose from the blood and decreases glucose production by the liver. Nobeglar-Uno 100IU Prefilled Pen 3 ml helps in improving glycaemic control, which in turn reduces the risk of progression of complications of diabetes like damage to the retina (retinopathy), impairment of the kidney (nephropathy), injury of nerve cells (neuropathy), delayed wound healing, diabetic foot ulcer and others. Besides this, Nobeglar-Uno 100IU Prefilled Pen 3 ml can be safely prescribed to pregnant and lactating mothers.

• Low blood sugar or hypoglycaemia

• Cold sweat

• Cool pale skin

• Nervousness

• Anxious feeling

• Unusual tiredness or weakness

• Confusion

• Difficulty in concentration

• Drowsiness

• Excessive hunger

• Temporary vision changes

• Headache

• Nausea

• Increased pulse or heartbeat (palpitation)

Nobeglar-Uno 100IU Prefilled Pen 3 ml is for subcutaneous (under the skin) use only and should never be administered intravenously (IV) or in the veins. If you are changing the brand of insulin or if you need to inject your insulin by another method, it should be done under strict medical supervision. Cases of heart failure were reported when pioglitazone was used with insulin, especially in patients at high risk of cardiac heart failure. The first symptoms of hyperglycaemia (high blood sugar level) may include symptoms like excessive thirst, dry mouth, increased frequency of urination, nausea, vomiting, drowsiness, flushed dry skin, loss of appetite and acetone odour of the breath. You should closely monitor these symptoms. Symptoms like heart failure, weight gain and oedema (fluid deposition in tissue) should not be overruled. It is advisable not to consume alcohol as it may increase or decrease your blood glucose level. Care should be taken while travelling across more than two time zones. Your doctor may adjust your insulin schedule. Nobeglar-Uno 100IU Prefilled Pen 3 ml may decrease the potassium level, leading to a state of hypokalaemia that, if left untreated, may lead to respiratory paralysis, irregular heartbeat rhythm, coma and even death. Do not take Nobeglar-Uno 100IU Prefilled Pen 3 ml if you have any low blood glucose levels, kidney, liver, or heart problems, or problems with alcohol or other prescription recreational drugs.

Drug-Drug Interactions: Nobeglar-Uno 100IU Prefilled Pen 3 ml may have an interaction with all other antidiabetic pills (sitagliptin), blood sugar enhancers (diazoxide), blood pressure-lowering pills (metoprolol, clonidine), antidepressants (lithium, fluoxetine), pain killers (aspirin, pentoxifylline, propoxyphene), anti TB drug (isoniazid), growth hormone (somatropin), thyroid hormone-related drugs (levothyroxine), antipsychotic medicines (phenothiazine, clozapine, olanzapine), anti-cholesterol drugs (fenofibrate), anti-asthmatic (epinephrine, salbutamol, terbutaline), female hormones like oestrogens and progestogens.

Drug-Food Interactions: Nobeglar-Uno 100IU Prefilled Pen 3 ml may interact with an ayurvedic, homoeopathy, Unani, herbal supplements or OTC items. Tell your doctor if you are using these products. Avoid drinking alcoholic beverages with Nobeglar-Uno 100IU Prefilled Pen 3 ml as it may raise or lower your blood sugar level.

Drug-Disease Interactions: Nobeglar-Uno 100IU Prefilled Pen 3 ml should not be given to patients with kidney disease, liver disease, low blood sugar/glucose level (hypoglycaemia), and low potassium level (hypokalaemia).

• ASPIRIN
• SITAGLIPTIN
• PREGABALIN
• METOPROLOL
• LEVOTHYROXINE SODIUM
• CLONIDINE
• LITHIUM
• FLUOXETINE
• RIFAMPICIN+ISONIAZID
• CLOZAPINE
• OLANZAPINE
• FENOFIBRATE
• EPINEPHRINE
• SALBUTAMOL
• ESTROGEN
• PROGESTERONE

• Exercise may lower your body’s need for insulin during and sometimes after physical activity.

• Exercise may also speed up the effect of an insulin dose, especially if the activity involves the area of the injection site (for example, the leg should not be used for injection just before running).

• Discuss with your doctor how to adjust your insulin regimen to accommodate exercise. 

• Avoid eating sugar food and prefer food cooked food low in calories.

• When travelling across more than two time zones, you should talk to your doctor concerning adjustments in your insulin schedule.

Change (rotate) your injection sites within the area you chose with each dose to reduce your risk of getting lipodystrophy (pitted or thickened skin) and localized cutaneous amyloidosis (skin with lumps) at the injection sites. Do not use the same spot for each injection or injection where the skin is pitted, thickened, lumpy, tender, bruised, scaly, hard, scarred or damaged.

Diabetes: Diabetes is a chronic or lifelong disease that prevents the body from utilizing insulin properly. Insulin is the hormone that controls sugar levels in the blood. Diabetes is a condition in which blood glucose levels are above normal. It is of two types: type-1 and type-2 diabetes. Type-1 diabetes is a condition in which the pancreas produces little or no insulin. Type-2 diabetes affects the way body processes the sugar. Symptoms of diabetes include lack of energy, tiredness, frequent urination, excess thirst, dry mouth, blurry vision, constant hunger, weight loss, and itchy skin.