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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Apxenta Tablet is used to treat Plaque psoriasis (scaly, itchy, and red patches on the skin), psoriasis arthritis (inflammation in the joints in people with psoriasis), and oral ulcers. It contains Apremilast, which blocks the action of some chemical messengers that are responsible for inflammation related to psoriatic arthritis and psoriasis and thus, lowers the signs and symptoms of these conditions.
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Composition :

APREMILAST-30MG

Manufacturer/Marketer :

Ajanta Pharma Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Apxenta Tablet

Apxenta Tablet is used to treat Plaque psoriasis (scaly, itchy, and red patches on the skin), psoriasis arthritis (inflammation in the joints in people with psoriasis), and oral ulcers. Psoriasis is a chronic, painful, nontransmissible, deactivating and damaging disease. It can happen at any age and is most common in the age group 50 to 69. Psoriatic arthritis is a type of arthritis that some people with psoriasis experience.

Apxenta Tablet contains Apremilast, a phosphodiesterase 4 (PDE4) inhibitor. Apxenta Tablet works by blocking the action of some chemical messengers that are responsible for inflammation related to psoriatic arthritis (inflammation in the joints in people with psoriasis) and psoriasis (scaly, itchy, and red patches on the skin) and, thus, lower the signs and symptoms of these conditions.

Take Apxenta Tablet as prescribed by your doctor. You are advised to take Apxenta Tablet for as long as your doctor has prescribed it for you, depending on your medical conditions. You may experience diarrhoea, vomiting, nausea, weight loss, and back pain. Most of these side effects of Apxenta Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Apxenta Tablet should not be taken in conditions like depression as it is getting worse with thoughts of suicide. Before starting Apxenta Tablet , please inform your doctor if you have any allergy to Apxenta Tablet and its parts. Apxenta Tablet not recommended for use in children and adolescents aged below 17 years. If you are pregnant or breastfeeding, ask your doctor for advice before taking this Apxenta Tablet . Apxenta Tablet does not affect the ability to drive and use machines.

Uses of Apxenta Tablet

Treatment of Plaque psoriasis, psoriasis arthritis, and oral ulcers caused by Behcet's disease.

Directions for Use

Take Apxenta Tablet as prescribed by your doctor. Your doctor determines the dose of the medicine based on your condition. Take Apxenta Tablet with or without food. Swallow the Apxenta Tablet as a whole with a glass of water. Do not crush, chew, or break it.

Medicinal Benefits

Apxenta Tablet is used in treating psoriatic arthritis; it decreases pain and swelling and may help improve flexibility in the affected joints. It is also used to treat moderate to severe plaque psoriasis (skin disease causes red, scaly patches to form on some areas of the body) in people who may benefit from medications). It is used to treat ulcers in the mouth in persons with Behcet's syndrome (a disease that results from blood vessel swelling in the body). Apxenta Tablet works by blocking the action of some chemical messengers responsible for inflammation related to psoriatic arthritis and psoriasis, thus lowering the signs and symptoms of these conditions.

How Apxenta Tablet Works

Apxenta Tablet contains Apremilast, a phosphodiesterase 4 (PDE4) inhibitor. Apxenta Tablet works by blocking the action of some chemical messengers that are responsible for inflammation related to psoriatic arthritis (inflammation in the joints in people with psoriasis) and psoriasis (scaly, itchy, and red patches on the skin) and, thus, lower the signs and symptoms of these conditions.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Apxenta Tablet

  • Diarrhea
  • Vomiting
  • Nausea
  • Weight loss
  • Back pain

What if I have taken an overdose of Apxenta Tablet

Do not take more than the prescribed dose of Apxenta Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Inform your doctor before using Apxenta Tablet , if you have previously had an allergic reaction (hypersensitivity). Before starting Apxenta Tablet , please inform your doctor if you have depression and suicidal thoughts. Inform your doctor before taking Apxenta Tablet if you have severe kidney problems. Inform your doctor while taking Apxenta Tablet if you lose weight without meaning to. Apxenta Tablet should not be taken in conditions like severe diarrhoea, nausea, and vomiting. Apxenta Tablet not recommended for use in children and adolescents aged below 17 years. If you are pregnant or breastfeeding, ask your doctor for advice before taking this Apxenta Tablet . Patients with rare hereditary galactose intolerance problems, total lactase deficiency or glucose-galactose malabsorption should not take Apxenta Tablet .

 

Drug-Drug Interactions

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ApremilastMitotane
Severe
ApremilastCarbamazepine
Severe

Drug-Drug Interactions

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ApremilastMitotane
Severe
How does the drug interact with Apxenta Tablet 10's:
Coadministration of Mitotane with Apxenta Tablet 10's may reduce the effectiveness of treatment.

How to manage the interaction:
Although taking Apxenta Tablet 10's and Mitotane together can cause an interaction, it can be taken if a doctor has suggested it. Do not discontinue any medications without consulting a doctor.
ApremilastCarbamazepine
Severe
How does the drug interact with Apxenta Tablet 10's:
Taking Apxenta Tablet 10's with carbamazepine can significantly reduce the blood levels of Apxenta Tablet 10's, which may make the medication less effective.

How to manage the interaction:
Taking Apxenta Tablet 10's with Carbamazepine together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
ApremilastRifapentine
Severe
How does the drug interact with Apxenta Tablet 10's:
Rifapentine may decrease the blood levels of Apxenta Tablet 10's, which may make Apxenta Tablet 10's less effective in treating the condition.

How to manage the interaction:
Although taking Apxenta Tablet 10's and Rifapentine together can cause an interaction, it can be taken if a doctor has suggested it. Do not stop using any medications without a doctor's advice.
ApremilastFosphenytoin
Severe
How does the drug interact with Apxenta Tablet 10's:
Coadministration of Fosphenytoin with Apxenta Tablet 10's may reduce the effectiveness of treatment.

How to manage the interaction:
Although taking Fosphenytoin and Apxenta Tablet 10's together can cause an interaction, it can be taken if a doctor has suggested it. Do not stop using any medications without talking to a doctor.
ApremilastRifabutin
Severe
How does the drug interact with Apxenta Tablet 10's:
Coadministration of Apxenta Tablet 10's and Rifabutin may reduce the blood levels of Apxenta Tablet 10's.

How to manage the interaction:
Although there is a possible interaction between Apxenta Tablet 10's and Rifabutin, you can take these medicines together if prescribed by a doctor. In case you experience any symptoms, consult a doctor. Do not discontinue any medications without consulting a doctor.
ApremilastEnzalutamide
Severe
How does the drug interact with Apxenta Tablet 10's:
Coadministration of Enzalutamide with Apxenta Tablet 10's may reduce the efficacy of treatment.

How to manage the interaction:
Although taking Apxenta Tablet 10's and Enzalutamide together can cause an interaction, it can be taken if a doctor has suggested it. Do not discontinue any medications without consulting a doctor.
ApremilastPrimidone
Severe
How does the drug interact with Apxenta Tablet 10's:
Coadministration of Apxenta Tablet 10's with primidone may decrease the blood levels of Apxenta Tablet 10's, which may make Apxenta Tablet 10's less effective in treating.

How to manage the interaction:
Although there is an interaction between Primidone and Apxenta Tablet 10's, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ApremilastNevirapine
Severe
How does the drug interact with Apxenta Tablet 10's:
Coadministration of Nevirapine with Apxenta Tablet 10's may decrease the blood levels of Apxenta Tablet 10's, which may make the medication less effective.

How to manage the interaction:
Although there is a possible interaction between Apxenta Tablet 10's and Nevirapine, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
ApremilastPhenobarbital
Severe
How does the drug interact with Apxenta Tablet 10's:
Coadministration of phenobarbital with Apxenta Tablet 10's can drastically lower Apxenta Tablet 10's levels in the blood, making the medicine less effective in treating.

How to manage the interaction:
Although taking phenobarbital with Apxenta Tablet 10's can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.
ApremilastRifampicin
Severe
How does the drug interact with Apxenta Tablet 10's:
Taking Apxenta Tablet 10's with rifampicin can decrease the blood levels of Apxenta Tablet 10's, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Apxenta Tablet 10's and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps strengthen muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep, as resting the muscles can help in reducing inflammation and swelling.
  • Follow heat or cold therapy, and apply a cold or hot compress on the joints for 15-20minutes regularly.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANTIPSORIATICS

Apxenta Tablet Substitute

Substitutes safety advice
  • Aprezo 30 mg Tablet 10's

    by AYUR

    29.25per tablet
  • Apraize-30 Tablet 10's

    by AYUR

    32.13per tablet
  • Mprila Tablet 10's

    by AYUR

    24.57per tablet
  • Atlast 30 Tablet 10's

    20.70per tablet
  • Aprenext 30 mg Tablet 10's

    by AYUR

    27.19per tablet
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Alcohol

Caution

Limit intake of alcohol, as this may increase the risk of serious side effects.

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Pregnancy

Caution

If you are pregnant, inform your doctor before taking Apxenta Tablet . Consult your doctor if you become pregnant while taking Apxenta Tablet .

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Breast Feeding

Caution

It is not known whether Apxenta Tablet may pass into breast milk or not. If you are breastfeeding, inform your doctor before taking Apxenta Tablet .

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Driving

Safe if prescribed

Apxenta Tablet has no or negligible influence on the ability to drive and use machines.

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Liver

Caution

Apxenta Tablet to be taken with caution, especially if you have a history of liver problems. Your doctor may adjust the dose of this medicine based on your condition.

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Kidney

Caution

Apxenta Tablet to be taken with caution, especially if you have a history of kidney diseases. Your doctor may adjust the dose of this medicine based on your condition.

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Children

Unsafe

Apxenta Tablet is not recommended for use in children and adolescents below 17 years.

FAQs

Apxenta Tablet is used to treat plaque psoriasis (scaly, itchy, and red patches on the skin), psoriatic arthritis (inflammation in the joints in people with psoriasis), and oral ulcers caused by Behcet's disease.
Apxenta Tablet works by blocking the action of some chemical messengers that are responsible for inflammation.
Yes, Apxenta Tablet may cause depression as a side effect. The patient may also have suicidal thoughts. Apxenta Tablet should be avoided in people with a history of depression. In case you develop any of these symptoms, Inform your doctor immediately.
Apxenta Tablet is used to treat plaque psoriasis (red, scaly, thick, itchy, painful patches on the skin) and psoriatic arthritis (a condition that causes joint pain and swelling). It is a long-period treatment and may take about 16 weeks to show an improvement.
Yes, Apxenta Tablet may cause a reduction in appetite, which may further lead to weight loss. You should monitor your weight frequently while on treatment with Apxenta Tablet . In case of big weight loss, inform your doctor. Your doctor may consider stopping Apxenta Tablet .
Rifampicin is an antibiotic. You should not take rifampicin if you are taking Apxenta Tablet . Rifampicin interferes with the working of Apxenta Tablet by reducing its levels, making it less effective. As a result, you may not see any recovery after taking Apxenta Tablet .
As soon as you recall, take the missed dose. If the next dose is approaching, skip the missing dose and resume your regular dosing regimen. Do not duplicate the dose to make up for a missing one.
No, Apxenta Tablet is not an immunosuppressant. It belongs to a class of drugs called phosphodiesterase 4 (PDE4) inhibitors which work by blocking the action of PDE4 that is found in inflammatory cells.
Take Apxenta Tablet as advised by the doctor. Swallow it as whole with a glass of water. Do not break, crush or chew it.
If you get pregnant during treatment with Apxenta Tablet , inform your doctor immediately. You are recommended to avoid pregnancy during treatment with Apxenta Tablet as it may harm unborn baby.
Apxenta Tablet may cause side effects such as nausea, vomiting, diarrhoea, back pain or weight loss. If these side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Ajanta House, Charkop, Kandivli West, Mumbai 400 067, India
Other Info - APX0003

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