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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Alizap Tablet is used to treat Plaque psoriasis (scaly, itchy, and red patches on the skin), psoriasis arthritis (inflammation in the joints in people with psoriasis), and oral ulcers. It contains Apremilast, which blocks the action of some chemical messengers that are responsible for inflammation related to psoriatic arthritis and psoriasis and thus, lowers the signs and symptoms of these conditions.
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Composition :

APREMILAST-30MG

Manufacturer/Marketer :

Biocon Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Alizap Tablet

Alizap Tablet is used to treat Plaque psoriasis (scaly, itchy, and red patches on the skin), psoriasis arthritis (inflammation in the joints in people with psoriasis), and oral ulcers. Psoriasis is a chronic, painful, nontransmissible, deactivating and damaging disease. It can happen at any age and is most common in the age group 50 to 69. Psoriatic arthritis is a type of arthritis that some people with psoriasis experience.

Alizap Tablet contains Apremilast, a phosphodiesterase 4 (PDE4) inhibitor. Alizap Tablet works by blocking the action of some chemical messengers that are responsible for inflammation related to psoriatic arthritis (inflammation in the joints in people with psoriasis) and psoriasis (scaly, itchy, and red patches on the skin) and, thus, lower the signs and symptoms of these conditions.

Take Alizap Tablet as prescribed by your doctor. You are advised to take Alizap Tablet for as long as your doctor has prescribed it for you, depending on your medical conditions. You may experience diarrhoea, vomiting, nausea, weight loss, and back pain. Most of these side effects of Alizap Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Alizap Tablet should not be taken in conditions like depression as it is getting worse with thoughts of suicide. Before starting Alizap Tablet , please inform your doctor if you have any allergy to Alizap Tablet and its parts. Alizap Tablet not recommended for use in children and adolescents aged below 17 years. If you are pregnant or breastfeeding, ask your doctor for advice before taking this Alizap Tablet . Alizap Tablet does not affect the ability to drive and use machines.

Uses of Alizap Tablet

Treatment of Plaque psoriasis, psoriasis arthritis, and oral ulcers caused by Behcet's disease.

Directions for Use

Take Alizap Tablet as prescribed by your doctor. Your doctor determines the dose of the medicine based on your condition. Take Alizap Tablet with or without food. Swallow the Alizap Tablet as a whole with a glass of water. Do not crush, chew, or break it.

Medicinal Benefits

Alizap Tablet is used in treating psoriatic arthritis; it decreases pain and swelling and may help improve flexibility in the affected joints. It is also used to treat moderate to severe plaque psoriasis (skin disease causes red, scaly patches to form on some areas of the body) in people who may benefit from medications). It is used to treat ulcers in the mouth in persons with Behcet's syndrome (a disease that results from blood vessel swelling in the body). Alizap Tablet works by blocking the action of some chemical messengers responsible for inflammation related to psoriatic arthritis and psoriasis, thus lowering the signs and symptoms of these conditions.

How Alizap Tablet Works

Alizap Tablet contains Apremilast, a phosphodiesterase 4 (PDE4) inhibitor. Alizap Tablet works by blocking the action of some chemical messengers that are responsible for inflammation related to psoriatic arthritis (inflammation in the joints in people with psoriasis) and psoriasis (scaly, itchy, and red patches on the skin) and, thus, lower the signs and symptoms of these conditions.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Alizap Tablet

  • Diarrhea
  • Vomiting
  • Nausea
  • Weight loss
  • Back pain

What if I have taken an overdose of Alizap Tablet

Do not take more than the prescribed dose of Alizap Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Inform your doctor before using Alizap Tablet , if you have previously had an allergic reaction (hypersensitivity). Before starting Alizap Tablet , please inform your doctor if you have depression and suicidal thoughts. Inform your doctor before taking Alizap Tablet if you have severe kidney problems. Inform your doctor while taking Alizap Tablet if you lose weight without meaning to. Alizap Tablet should not be taken in conditions like severe diarrhoea, nausea, and vomiting. Alizap Tablet not recommended for use in children and adolescents aged below 17 years. If you are pregnant or breastfeeding, ask your doctor for advice before taking this Alizap Tablet . Patients with rare hereditary galactose intolerance problems, total lactase deficiency or glucose-galactose malabsorption should not take Alizap Tablet .

 

Drug-Drug Interactions

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ApremilastCarbamazepine
Severe
ApremilastFosphenytoin
Severe

Drug-Drug Interactions

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ApremilastCarbamazepine
Severe
How does the drug interact with Alizap Tablet 10's:
Taking Alizap Tablet 10's with carbamazepine can significantly reduce the blood levels of Alizap Tablet 10's, which may make the medication less effective.

How to manage the interaction:
Taking Alizap Tablet 10's with Carbamazepine together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
ApremilastFosphenytoin
Severe
How does the drug interact with Alizap Tablet 10's:
Coadministration of Fosphenytoin with Alizap Tablet 10's may reduce the effectiveness of treatment.

How to manage the interaction:
Although taking Fosphenytoin and Alizap Tablet 10's together can cause an interaction, it can be taken if a doctor has suggested it. Do not stop using any medications without talking to a doctor.
ApremilastRifapentine
Severe
How does the drug interact with Alizap Tablet 10's:
Rifapentine may decrease the blood levels of Alizap Tablet 10's, which may make Alizap Tablet 10's less effective in treating the condition.

How to manage the interaction:
Although taking Alizap Tablet 10's and Rifapentine together can cause an interaction, it can be taken if a doctor has suggested it. Do not stop using any medications without a doctor's advice.
ApremilastNevirapine
Severe
How does the drug interact with Alizap Tablet 10's:
Coadministration of Nevirapine with Alizap Tablet 10's may decrease the blood levels of Alizap Tablet 10's, which may make the medication less effective.

How to manage the interaction:
Although there is a possible interaction between Alizap Tablet 10's and Nevirapine, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
ApremilastPhenobarbital
Severe
How does the drug interact with Alizap Tablet 10's:
Coadministration of phenobarbital with Alizap Tablet 10's can drastically lower Alizap Tablet 10's levels in the blood, making the medicine less effective in treating.

How to manage the interaction:
Although taking phenobarbital with Alizap Tablet 10's can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.
ApremilastMitotane
Severe
How does the drug interact with Alizap Tablet 10's:
Coadministration of Mitotane with Alizap Tablet 10's may reduce the effectiveness of treatment.

How to manage the interaction:
Although taking Alizap Tablet 10's and Mitotane together can cause an interaction, it can be taken if a doctor has suggested it. Do not discontinue any medications without consulting a doctor.
ApremilastPrimidone
Severe
How does the drug interact with Alizap Tablet 10's:
Coadministration of Alizap Tablet 10's with primidone may decrease the blood levels of Alizap Tablet 10's, which may make Alizap Tablet 10's less effective in treating.

How to manage the interaction:
Although there is an interaction between Primidone and Alizap Tablet 10's, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ApremilastRifampicin
Severe
How does the drug interact with Alizap Tablet 10's:
Taking Alizap Tablet 10's with rifampicin can decrease the blood levels of Alizap Tablet 10's, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Alizap Tablet 10's and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
ApremilastPhenytoin
Severe
How does the drug interact with Alizap Tablet 10's:
Coadministration of Phenytoin with Alizap Tablet 10's may reduce the blood levels of Alizap Tablet 10's, which may reduce effectiveness in treatment.

How to manage the interaction:
Although taking Phenytoin and Alizap Tablet 10's together can result in an interaction, it can be taken if a doctor has prescribed it. Without consulting a doctor, never stop taking any drugs.
ApremilastEnzalutamide
Severe
How does the drug interact with Alizap Tablet 10's:
Coadministration of Enzalutamide with Alizap Tablet 10's may reduce the efficacy of treatment.

How to manage the interaction:
Although taking Alizap Tablet 10's and Enzalutamide together can cause an interaction, it can be taken if a doctor has suggested it. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps strengthen muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep, as resting the muscles can help in reducing inflammation and swelling.
  • Follow heat or cold therapy, and apply a cold or hot compress on the joints for 15-20minutes regularly.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANTIPSORIATICS

Alizap Tablet Substitute

Substitutes safety advice
  • Aprezo 30 mg Tablet 10's

    by AYUR

    29.25per tablet
  • Apraize-30 Tablet 10's

    by AYUR

    32.13per tablet
  • Mprila Tablet 10's

    by AYUR

    24.57per tablet
  • Atlast 30 Tablet 10's

    19.80per tablet
  • Apxenta Tablet 10's

    by AYUR

    27.72per tablet
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Alcohol

Caution

Limit intake of alcohol, as this may increase the risk of serious side effects.

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Pregnancy

Caution

If you are pregnant, inform your doctor before taking Alizap Tablet . Consult your doctor if you become pregnant while taking Alizap Tablet .

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Breast Feeding

Caution

It is not known whether Alizap Tablet may pass into breast milk or not. If you are breastfeeding, inform your doctor before taking Alizap Tablet .

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Driving

Safe if prescribed

Alizap Tablet has no or negligible influence on the ability to drive and use machines.

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Liver

Caution

Alizap Tablet to be taken with caution, especially if you have a history of liver problems. Your doctor may adjust the dose of this medicine based on your condition.

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Kidney

Caution

Alizap Tablet to be taken with caution, especially if you have a history of kidney diseases. Your doctor may adjust the dose of this medicine based on your condition.

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Children

Unsafe

Alizap Tablet is not recommended for use in children and adolescents below 17 years.

FAQs

Alizap Tablet is used to treat plaque psoriasis (scaly, itchy, and red patches on the skin), psoriatic arthritis (inflammation in the joints in people with psoriasis), and oral ulcers caused by Behcet's disease.
Alizap Tablet works by blocking the action of some chemical messengers that are responsible for inflammation.
Yes, Alizap Tablet may cause depression as a side effect. The patient may also have suicidal thoughts. Alizap Tablet should be avoided in people with a history of depression. In case you develop any of these symptoms, Inform your doctor immediately.
Alizap Tablet is used to treat plaque psoriasis (red, scaly, thick, itchy, painful patches on the skin) and psoriatic arthritis (a condition that causes joint pain and swelling). It is a long-period treatment and may take about 16 weeks to show an improvement.
Yes, Alizap Tablet may cause a reduction in appetite, which may further lead to weight loss. You should monitor your weight frequently while on treatment with Alizap Tablet . In case of big weight loss, inform your doctor. Your doctor may consider stopping Alizap Tablet .
Rifampicin is an antibiotic. You should not take rifampicin if you are taking Alizap Tablet . Rifampicin interferes with the working of Alizap Tablet by reducing its levels, making it less effective. As a result, you may not see any recovery after taking Alizap Tablet .
As soon as you recall, take the missed dose. If the next dose is approaching, skip the missing dose and resume your regular dosing regimen. Do not duplicate the dose to make up for a missing one.
No, Alizap Tablet is not an immunosuppressant. It belongs to a class of drugs called phosphodiesterase 4 (PDE4) inhibitors which work by blocking the action of PDE4 that is found in inflammatory cells.
Take Alizap Tablet as advised by the doctor. Swallow it as whole with a glass of water. Do not break, crush or chew it.
If you get pregnant during treatment with Alizap Tablet , inform your doctor immediately. You are recommended to avoid pregnancy during treatment with Alizap Tablet as it may harm unborn baby.
Alizap Tablet may cause side effects such as nausea, vomiting, diarrhoea, back pain or weight loss. If these side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

20th KM, Hosur Road, Electronic City, Bangalore, India - 560 100
Other Info - ALI0092

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