Amphonex 50 mg Injection belongs to a class of medication called 'antifungal' used to treat severe fungal infections like leishmaniasis. A fungal infection is a disease in which fungi attack the tissue and cause infection. Fungi are commonly present in nature but do not cause infections normally. However, if the person has a weak immune system, certain types of fungi may infect them. 

Amphonex 50 mg Injection contains Amphotericin B, which kills fungi by destroying the fungal outer cell membrane. The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents.

Amphonex 50 mg Injection is given by a doctor or nurse. In some cases, you may experience fever, chills, irregular heartbeat, high or low blood pressure, breathing problems, nausea, vomiting, headache, shaking, muscle cramps or pain. Most of these side effects of Amphonex 50 mg Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Amphonex 50 mg Injection or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Amphonex 50 mg Injection. Amphonex 50 mg Injection is not recommended for children below one month as the safety and effectiveness were not established. Avoid driving after taking Amphonex 50 mg Injection as it may affect your ability to drive. If you experience severe adverse effects such as chest pain or difficulty in breathing, or encephalopathy (a brain disease which may cause you to behave strangely, be confused or feel drowsy), seek immediate medical help.

Amphonex 50 mg Injection contains Amphotericin B, an antifungal used to treat severe fungal infections. The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Amphonex 50 mg Injection damages fungal cell membranes and kills fungi. Amphonex 50 mg Injection is used to treat infections such as blood infection with candida, cryptococcus, fusarium, zygomycetes, aspergillus, coccidiodes or blastomycetes, or cryptococcal meningitis (inflammation of the brain).

• Fever

• Chills
• Irregular heartbeat
• High or low blood pressure
• Breathing problems
• Nausea
• Vomiting
• Headache
• Shaking
• Muscle cramps or pain

If you are allergic to Amphotericin B or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Amphonex 50 mg Injection. Amphonex 50 mg Injection is not recommended for children below one month as the safety and effectiveness were not established. Avoid driving after taking Amphonex 50 mg Injection as it may affect your ability to drive. If you experience severe adverse effects such as chest pain, difficulty breathing, or encephalopathy (a brain disease that may cause you to behave strangely, be confused or feel drowsy), seek immediate medical help. If you have diabetes, electrolyte imbalance (low magnesium or potassium levels in the blood), kidney, liver or heart problems, inform your doctor before taking Amphonex 50 mg Injection.

Drug-Drug Interaction: Amphonex 50 mg Injection may interact with an anti-HIV drug (zidovudine), immunosuppressant (ciclosporin), antifungal (flucytosine), water pills (furosemide), anticancer drug (methotrexate).

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: If you have diabetes, electrolyte imbalance (low magnesium or potassium levels in the blood), kidney, liver or heart problems, inform your doctor before taking Amphonex 50 mg Injection.

• ZIDOVUDINE
• CICLOSPORIN
• FLUCYTOSINE
• FUROSEMIDE
• METHOTREXATE

• Wash your hands regularly and keep your hands clean to prevent the spread of germs.

• Avoid dusty activities and digging in the soil.
• Wear shoes, a long-sleeved t-shirt and long pants while doing outdoor activities such as yard work, gardening or visiting wooded areas to protect from fungus commonly present in the environment.
• Maintain a diet that is low in sugar, refined carbohydrates, mould-containing foods and yeast.

• Regular blood tests are recommended while taking Amphonex 50 mg Injection to monitor blood, liver or kidney functioning and potassium levels.

Fungal infection is a disease in which fungi attack the tissue and cause infection. Fungi are commonly present in nature but do not cause infections normally. However, if the person has a weak immune system, certain types of fungi may infect them. Cryptococcal meningitis is a fungal infection of tissues covering the spinal cord (meninges) and brain. The symptoms include headache, hallucinations, fever, stiff neck, sensitivity to light, nausea and vomiting. Fungal infections in the lungs may be more serious and life-threatening and often cause symptoms similar to tuberculosis or bacterial pneumonia.