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Ambisome Injection 1's

Ambisome Injection 1's

Prescription drug
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Synonym

LIPOSOMAL AMPHOTERICIN B

Manufacturer/Marketer

Mylan Pharmaceuticals Pvt Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-25

for this medicine

About Ambisome Injection

Ambisome Injection belongs to a class of medication called 'antifungal' used to treat severe fungal infections like leishmaniasis. A fungal infection is a disease in which fungi attack the tissue and cause infection. Fungi are commonly present in nature but do not cause infections normally. However, if the person has a weak immune system, certain types of fungi may infect them. 

Ambisome Injection contains Amphotericin B, which kills fungi by destroying the fungal outer cell membrane. The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents.

Ambisome Injection is given by a doctor or nurse. In some cases, you may experience fever, chills, irregular heartbeat, high or low blood pressure, breathing problems, nausea, vomiting, headache, shaking, muscle cramps or pain. Most of these side effects of Ambisome Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Ambisome Injection or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Ambisome Injection. Ambisome Injection is not recommended for children below one month as the safety and effectiveness were not established. Avoid driving after taking Ambisome Injection as it may affect your ability to drive. If you experience severe adverse effects such as chest pain or difficulty in breathing, or encephalopathy (a brain disease which may cause you to behave strangely, be confused or feel drowsy), seek immediate medical help.

Uses of Ambisome Injection

Treatment of Severe fungal infections

Medicinal Benefits

Ambisome Injection contains Amphotericin B, an antifungal used to treat severe fungal infections. The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Ambisome Injection damages fungal cell membranes and kills fungi. Ambisome Injection is used to treat infections such as blood infection with candida, cryptococcus, fusarium, zygomycetes, aspergillus, coccidiodes or blastomycetes, or cryptococcal meningitis (inflammation of the brain).

Directions for Use

Ambisome Injection will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Ambisome Injection

  • Fever

  • Chills
  • Irregular heartbeat
  • High or low blood pressure
  • Breathing problems
  • Nausea
  • Vomiting
  • Headache
  • Shaking
  • Muscle cramps or pain

Drug Warnings

If you are allergic to Amphotericin B or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Ambisome Injection. Ambisome Injection is not recommended for children below one month as the safety and effectiveness were not established. Avoid driving after taking Ambisome Injection as it may affect your ability to drive. If you experience severe adverse effects such as chest pain, difficulty breathing, or encephalopathy (a brain disease that may cause you to behave strangely, be confused or feel drowsy), seek immediate medical help. If you have diabetes, electrolyte imbalance (low magnesium or potassium levels in the blood), kidney, liver or heart problems, inform your doctor before taking Ambisome Injection.

Drug Interactions

Drug-Drug Interaction: Ambisome Injection may interact with an anti-HIV drug (zidovudine), immunosuppressant (ciclosporin), antifungal (flucytosine), water pills (furosemide), anticancer drug (methotrexate).

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: If you have diabetes, electrolyte imbalance (low magnesium or potassium levels in the blood), kidney, liver or heart problems, inform your doctor before taking Ambisome Injection.

Drug-Drug Interactions Checker List

  • ZIDOVUDINE
  • CICLOSPORIN
  • FLUCYTOSINE
  • FUROSEMIDE
  • METHOTREXATE

Habit Forming

No

Diet & Lifestyle Advise

  • Wash your hands regularly and keep your hands clean to prevent the spread of germs.

  • Avoid dusty activities and digging in the soil.
  • Wear shoes, a long-sleeved t-shirt and long pants while doing outdoor activities such as yard work, gardening or visiting wooded areas to protect from fungus commonly present in the environment.
  • Maintain a diet that is low in sugar, refined carbohydrates, mould-containing foods and yeast.

Special Advise

  • Regular blood tests are recommended while taking Ambisome Injection to monitor blood, liver or kidney functioning and potassium levels.

Disease/Condition Glossary

Fungal infection is a disease in which fungi attack the tissue and cause infection. Fungi are commonly present in nature but do not cause infections normally. However, if the person has a weak immune system, certain types of fungi may infect them. Cryptococcal meningitis is a fungal infection of tissues covering the spinal cord (meninges) and brain. The symptoms include headache, hallucinations, fever, stiff neck, sensitivity to light, nausea and vomiting. Fungal infections in the lungs may be more serious and life-threatening and often cause symptoms similar to tuberculosis or bacterial pneumonia.

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Alcohol

Caution

The interaction of Ambisome Injection with alcohol is unknown. Please consult your doctor if you have any concerns regarding this.

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Pregnancy

Consult your doctor

Ambisome Injection is a Category B pregnancy drug and is given to a pregnant woman if the doctor thinks the benefits outweigh the risks. Please consult your doctor if you are pregnant or planning pregnancy.

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Breast Feeding

Consult your doctor

It is unknown whether Ambisome Injection is excreted in human milk. If you are breastfeeding, inform your doctor before receiving this injection.

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Driving

Caution

Avoid driving after taking Ambisome Injection as it may affect your ability to drive or operate machinery.

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Liver

Consult your doctor

Inform your doctor if you have a history of liver diseases/conditions before receiving Ambisome Injection.

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Kidney

Consult your doctor

Inform your doctor if you have a history of kidney diseases/conditions before receiving Ambisome Injection.

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Children

Caution

Ambisome Injection is not recommended for children below one month as the safety and effectiveness were not established.

Country of origin

INDIA

Manufacturer/Marketer address

401, LSC, C-Block, Mohan Place Saraswati Vihar Delhi DL 110034 In
Other Info - AMB0029

Author Details

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FAQs

Ambisome Injection is used to treat severe fungal infections like leishmaniasis.
Ambisome Injection contains Amphotericin B, an antifungal that works by damaging fungal cell membranes, thereby killing fungi.
You are not recommended to take Ambisome Injection with furosemide as co-administration of these medicines may increase the risk of hypokalaemia (low potassium levels in the blood), and in severe cases, it may lead to paralysis, muscle weakness, irregular heart rhythm, difficulty in breathing or swallowing. However, please consult your doctor before taking Ambisome Injection with other medicines.
Ambisome Injection may cause blue lips and skin, probably during infusion or in the initial 2 days of treatment. However, your doctor or nurse may arrange certain simple treatments to control such adverse effects.
Yes, a test dose of Ambisome Injection may be given in smaller amounts before starting the treatment to check if you are sensitive to any of the ingredients.
You are recommended to use Ambisome Injection for as long as your doctor has prescribed it. However, the usual treatment is for a minimum of 14 days. Please consult a doctor if you experience any difficulty while taking Ambisome Injection.
Ambisome Injection is not used to treat viral infections. Ambisome Injection is an antifungal that kills fungi and is used to treat severe fungal infections.

Disclaimer

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