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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Amlosafe MT 50 Tablet belongs to the class of antihypertensive medicines used in the treatment of high blood pressure. This medicine also helps reduce the chances of heart problems such as heart attack and stroke. It is a combination medicine which suppress the contraction of blood vessels and promote smooth blood flow. It also alters the response to nerve impulses in the heart thereby making the heart pump blood easier. Common side effects include headache, nausea, dizziness, stomach upset, and weakness.
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Manufacturer/Marketer :

Aristo Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Amlosafe MT 50 Tablet

Amlosafe MT 50 Tablet is an antihypertensive agent used to treat high blood pressure/hypertension and angina pectoris. High blood pressure is a condition in which the blood exerts increased pressure on the walls of blood vessels. Angina is basically a pain in the heart and chest. 

Amlosafe MT 50 Tablet contains Metoprolol succinate and Amlodipine. Metoprolol succinate works by slowing down the heart rate, thereby making it more efficient at pumping blood throughout the body. Amlodipine relaxes the blood vessels, thereby improving blood flow. Together, Amlosafe MT 50 Tablet helps treat high blood pressure.

Take Amlosafe MT 50 Tablet as prescribed. In some cases, Amlosafe MT 50 Tablet may cause certain common side effects such as tiredness, dizziness, headache, ankle swelling and slow heart rate. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist or worsen.

It is advisable to inform the doctor if you are allergic to any of its components. Consult your doctor if you are pregnant, planning to get pregnant, or breastfeeding. Keep your doctor informed in case you are due to undergo any surgery or dental procedure. Avoid consuming alcohol with Amlosafe MT 50 Tablet as there may be an interaction. Amlosafe MT 50 Tablet  may cause dizziness; therefore, drive only if you are alert.

Uses of Amlosafe MT 50 Tablet

Treatment of Hypertension and Angina pectoris

Directions for Use

Take Amlosafe MT 50 Tablet with or without food as directed by the physician. Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Amlosafe MT 50 Tablet is a combination antihypertensive medication containing Metoprolol succinate and Amlodipine. It is used primarily to treat hypertension and to relax the blood vessels for seamless flow of blood. Metoprolol succinate is a beta-blocker that eases the symptoms of hypertension by blocking catecholamines that lead to increased pressure and heart rate. Amlodipine is a calcium channel blocker that decreases blood pressure by preventing the influx of calcium ions into cells and by enlarging and relaxing arteries. In addition, Amlosafe MT 50 Tablet also reduces the oxygen demands of the heart, relaxing the heart and blood vessels and requiring the heart to do less work.

How Amlosafe MT 50 Tablet Works

Amlosafe MT 50 Tablet contains Metoprolol succinate and Amlodipine. Metoprolol succinate works by slowing down the heart rate, thereby making it more efficient at pumping blood throughout the body. Amlodipine relaxes the blood vessels, thereby improving blood flow. Together, Amlosafe MT 50 Tablet helps treat high blood pressure.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Amlosafe MT 50 Tablet

  • Tiredness
  • Dizziness
  • Headache
  • Ankle swelling
  • Slow heart rate
  • Stomach pain
  • Shortness of breath
  • Rash or itch
  • Cold hands and feet

What if I have taken an overdose of Amlosafe MT 50 Tablet

Do not take more than the prescribed dose. Overdose of Amlosafe MT 50 Tablet may cause low blood pressure, slow pulse rate, shortness of breath, low blood sugar, dizziness, feeling sick and blue discolouration of the skin. Seek immediate medical attention if you suspect that you might have taken an overdose of this medicine.

Drug Warnings

Amlosafe MT 50 Tablet should not be used in case of any known allergy to either of the components. Amlosafe MT 50 Tablet should be used with caution in case of high risk or previous history of any arterial or thrombotic disorders, shock, cardiovascular health disorders, diabetes, heart failure, or any disease-causing psoriasis. Please inform your doctor in case of any history of an overactive thyroid, asthma, phaeochromocytoma (high BP due to a tumour in the adrenal glands), myasthenia gravis (neuromuscular disorder), COPD, heart block, liver disease or renal disease. Consult your doctor before using Amlosafe MT 50 Tablet during pregnancy or breastfeeding. Keep your doctor informed in case you are waiting to undergo any surgery or dental procedure. Amlosafe MT 50 Tablet may interact with alcohol, please consult your doctor before use. Amlosafe MT 50 Tablet may cause dizziness, so drive or operate heavy machinery only if you are alert. 

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
AmlodipineTizanidine
Severe

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
How does the drug interact with Amlosafe MT 50 Tablet 10's:
Using Amlosafe MT 50 Tablet 10's together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Amlosafe MT 50 Tablet 10's with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
AmlodipineTizanidine
Severe
How does the drug interact with Amlosafe MT 50 Tablet 10's:
Co-administration of Tizanidine and Amlosafe MT 50 Tablet 10's can increase the risk or severity of developing side effects like low blood pressure.

How to manage the interaction:
Although co-administration of Amlosafe MT 50 Tablet 10's with tizanidine can result in an interaction, it can be taken when a doctor has advised it. However, if you experience headache, dizziness, palpitations, or irregular heart rate while taking these drugs, contact the doctor immediately. Use caution while getting up from a sitting or sleeping position and avoid driving or using dangerous machinery. Do not discontinue any medications without consulting the doctor.
AmlodipinePrimidone
Severe
How does the drug interact with Amlosafe MT 50 Tablet 10's:
Using Amlosafe MT 50 Tablet 10's and primidone together may lower Amlosafe MT 50 Tablet 10's blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of Amlosafe MT 50 Tablet 10's with primidone can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineNitisinone
Severe
How does the drug interact with Amlosafe MT 50 Tablet 10's:
Coadministration of Amlosafe MT 50 Tablet 10's and Nitisinone may increase the blood levels and effects of Nitisinone.

How to manage the interaction:
Taking Nitisinone with Amlosafe MT 50 Tablet 10's together can result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms or if you feel unwell after taking your medication, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice.
AmlodipineMitotane
Severe
How does the drug interact with Amlosafe MT 50 Tablet 10's:
Using Amlosafe MT 50 Tablet 10's and mitotane together may drastically lower Amlosafe MT 50 Tablet 10's blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of Amlosafe MT 50 Tablet 10's with mitotane can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineIdelalisib
Severe
How does the drug interact with Amlosafe MT 50 Tablet 10's:
Coadministration of Amlosafe MT 50 Tablet 10's and Idelalisib may raise Amlosafe MT 50 Tablet 10's levels in the blood this may lead to serious side effects (irregular heart rhythm, fluid retention, swelling, heart failure, and abnormally low blood pressure).

How to manage the interaction:
Although taking Amlosafe MT 50 Tablet 10's with idelalisib can result in an interaction, it can be taken if a doctor has advised it. However, if you experience dizziness or fainting, sudden, unexplained weight gain, swelling of the hands, ankles, or feet, chest discomfort, or trouble breathing while taking these drugs, consult the doctor. Use caution while getting up from a sitting or sleeping position and avoid driving or using dangerous machinery. Do not stop using any medications without a doctor's advice.
AmlodipineDolasetron
Severe
How does the drug interact with Amlosafe MT 50 Tablet 10's:
Using dolasetron together with Amlosafe MT 50 Tablet 10's can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
There may be a possibility of interaction between Amlosafe MT 50 Tablet 10's and Dolasetron, but it can be taken if prescribed by a doctor. If you have any of these symptoms, like feeling dizzy, lightheaded, or your heart beating irregularly, it's important to call a doctor right away. Do not stop using any medications without a doctor's advice.
AmlodipineRifampicin
Severe
How does the drug interact with Amlosafe MT 50 Tablet 10's:
Coadministration of Amlosafe MT 50 Tablet 10's and rifampicin together may lower Amlosafe MT 50 Tablet 10's blood levels, which makes the medicine less effective.

How to manage the interaction:
Although there is an interaction between Amlosafe MT 50 Tablet 10's and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
AmlodipineRifapentine
Severe
How does the drug interact with Amlosafe MT 50 Tablet 10's:
Coadministration of Amlosafe MT 50 Tablet 10's and Rifapentine may significantly reduce the blood levels of Amlosafe MT 50 Tablet 10's, which may make the medication less effective.

How to manage the interaction:
There may be a possibility of interaction between Amlosafe MT 50 Tablet 10's and Rifapentine, but it can be taken if prescribed by a doctor. If you have any symptoms, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
AmlodipineRifabutin
Severe
How does the drug interact with Amlosafe MT 50 Tablet 10's:
Using Amlosafe MT 50 Tablet 10's and rifabutin together may lower Amlosafe MT 50 Tablet 10's blood levels, which makes the medicine less effective.

How to manage the interaction:
Although there is an interaction between Amlosafe MT 50 Tablet 10's with rifabutin, but it can be taken if a doctor has advised it. Consult the doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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AMLODIPINE-5MG+METOPROLOL SUCCINATE-50MGFruit juices, Fruits
Moderate

Drug-Food Interactions

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AMLODIPINE-5MG+METOPROLOL SUCCINATE-50MGFruit juices, Fruits
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking Amlodipine and Metoprolol with grapefruit and grapefruit juice significantly increases the metabolism of Amlodipine. Avoid taking Amlodipine and Metoprolol with grapefruit and grapefruit juice.

Diet & Lifestyle Advise

  • Limit the intake of salt in your diet.
  • Cut back on foods that are high in fat and cholesterol.
  • Eat more fruits, vegetables and whole-grain foods.
  • Avoid taking Amlosafe MT 50 Tablet with grapefruit juice as there may be an interaction.
  • Avoid tobacco use. Inform your doctor in case of marijuana use.
  • Dress warmly, as Amlosafe MT 50 Tablet may cause cold extremities.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Amlosafe MT 50 Tablet Substitute

Substitutes safety advice
  • Mprol AM 5mg/50mg Tablet 10's

    4.32per tablet
  • Amlodac M Tablet 15's

    by AYUR

    12.21per tablet
  • Mettop AM Tablet 10's

    by AYUR

    8.82per tablet
  • Metopt AM Tablet 10's

    10.44per tablet
  • Metonce-AM 50/5 Tablet 10's

    7.34per tablet
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Alcohol

Unsafe

You are advised not to take alcohol with Amlosafe MT 50 Tablet as there may be an interaction, reducing the therapeutic effects of Amlosafe MT 50 Tablet . Please consult your doctor if you have any concerns.

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Pregnancy

Caution

Amlosafe MT 50 Tablet may be used in pregnancy only if absolutely warranted. Please consult your doctor if you have any concerns.

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Breast Feeding

Caution

Amlosafe MT 50 Tablet is not recommended for use during breastfeeding. Please consult your doctor if you have any concerns.

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Driving

Caution

Amlosafe MT 50 Tablet may cause dizziness or loss of alertness, which may affect your ability to drive.

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Liver

Caution

Amlosafe MT 50 Tablet is not recommended for use in those with established liver disease. Please consult your doctor in case of any concerns.

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Kidney

Caution

Amlosafe MT 50 Tablet is probably safe on the kidney but should be used with caution in those with renal impairment. Please consult your doctor in case of any concerns.

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Children

Unsafe

Amlosafe MT 50 Tablet is not recommended for use in children below 12 years of age. Please consult your physician if you have any concerns.

FAQs

Amlosafe MT 50 Tablet is used to treat high blood pressure/hypertension and angina pectoris.Â
Amlosafe MT 50 Tablet works by reducing the workload on the heart and vessels and relaxing the vessels to ensure a fluid flow of blood, easing any hypertension and effects of the same.
Do not stop taking Amlosafe MT 50 Tablet without consulting your doctor as it may lead to a rise in blood pressure. To treat your condition effectually, continue taking Amlosafe MT 50 Tablet for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Amlosafe MT 50 Tablet .
Hyponatremia (a term for low blood sodium levels) often results in lowering blood pressure and falls. One of the not so common side-effects of Amlosafe MT 50 Tablet is dizziness and lowered BP. Hence, it is best to consult your physician before taking Amlosafe MT 50 Tablet if you suffer from this condition.
Light-headedness could be a side-effect of Amlosafe MT 50 Tablet . It occurs due to low blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking, instead lie down and get up slowly only when you feel better. People taking Amlosafe MT 50 Tablet are advised to regularly monitor their blood pressure levels to avoid unpleasant events.
Amlosafe MT 50 Tablet is not known to affect fertility. However, not enough literature and studies exist to ascertain the effect of Amlosafe MT 50 Tablet on fertility. Please consult your doctor in case of any concerns.
Amlosafe MT 50 Tablet may cause certain common side effects such as tiredness, dizziness, headache, ankle swelling and slow heart rate. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist or worsen.
Change your lifestyle in a few essential ways to control your blood pressure. Start by moving; on most days of the week, try to get in at least 30 minutes of exercise, such as swimming or brisk walking. Next, have a well-balanced diet that is rich in fruits, vegetables, lean protein, and whole foods while being low in processed foods, salt, and bad fats. Keep an eye on your weight, drink moderately, and learn stress-reduction techniques like deep breathing or meditation. Aim for 7-8 hours of sleep per night and stay hydrated throughout the day. Try to give up smoking and limit your daily caffeine consumption to one cup of coffee. Don't forget to consult your healthcare practitioner before making any significant adjustments.
Yes. It is effective. Even so, the effectiveness of Amlosafe MT 50 Tablet depends on various factors, such as the individual's medical history, dosage, and response to the medication. It's important to consult with a healthcare professional to determine if this medication is appropriate for your specific condition and to monitor its effectiveness.
Amlosafe MT 50 Tablet is not typically considered a habit-forming medication.
Take Amlosafe MT 50 Tablet as directed. Swallow the tablet whole with water, and take it at the same time each day. Don't crush or chew the tablet. Continue taking the medication even if you feel well, as it helps control your condition. If you need to stop, consult your doctor first to avoid any issues. Regularly check your blood pressure and heart rate, and follow up with your doctor to adjust your dosage as needed.
Amlosafe MT 50 Tablet should be stored in a cool,and dry place away from sunlight. Keep Amlosafe MT 50 Tablet out of the sight and reach of children.
It is not advisable to smoke when taking Amlosafe MT 50 Tablet . Smoking may lessen this medication's effectiveness and heart-healthy improvement effects. In addition to improving your general health, quitting smoking will help your medication function better.
Amlosafe MT 50 Tablet may interact with other medications. Before taking it, consult your doctor to ensure safe use, especially if you're already taking other medications. Never combine it with other medications without your doctor's guidance.
Before taking any medication, including Amlosafe MT 50 Tablet , be sure to tell your doctor if you have any allergies or health conditions or are pregnant or breastfeeding. This will help ensure your safety and avoid any potential interactions or harm.
Amlosafe MT 50 Tablet is not recommended for use in children below 12 years of age. Please consult your physician if you have any concerns.

Country of origin

India

Manufacturer/Marketer address

Mercantile Chamber, 3rd Floor, 12, J.N. Heredia Marg, Ballard Estate, Mumbai – 400 001, India.
Other Info - AML0356

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