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Ramipril

About Ramipril

Ramipril is used to treat high blood pressure (hypertension) and reduce the risk of having a heart attack, stroke, or heart failure. High blood pressure is a chronic condition in which the pressure in the blood vessels is high.

Ramipril contains Ramipril, which relaxes and widens the blood vessels, making it easier for the heart to pump blood to all parts of the body.

In some cases, Ramipril may cause common side effects like headache, dizziness, fatigue, and cough. Most of these side effects do not require medical attention and will resolve gradually over time. Talk to your doctor if you experience these side effects persistently.

Take Ramipril with or without food. Do not chew, crush, or break Ramipril. Swallow it as a whole with a glass of water. Take Ramipril at the same time every day as prescribed by your doctor.

Inform your doctor if you are allergic to Ramipril. Try not to stop taking it on your own, as it may cause a sudden increase in blood pressure, chest pain or heart attack. Regular monitoring of blood pressure, electrolyte levels, and kidney function is advised while taking Ramipril. Avoid taking Ramipril if you are pregnant or breastfeeding.

Uses of Ramipril

Ramipril is used in the treatment of Hypertension (high blood pressure), Prevention of heart attack, stroke, and heart failure. The detailed uses of Ramipril are as follows: • Treatment of Hypertension: Ramipril controls hypertension by relaxing blood vessels and lowering blood pressure, making it easier for the heart to pump blood. • Prevention of Cardiovascular Risk: Ramipril protects against heart attack, stroke, failure and other cardiovascular complications by lowering blood pressure and reducing heart strain. • Kidney Protection: Ramipril reduces the risk or delays the worsening of kidney problems by lowering blood pressure and slowing kidney disease progression.

Medicinal Benefits

  • Ramipril is used alone or in combination with other medicines to treat high blood pressure.
  • Ramipril relaxes and widens the blood vessels, making it easier for the heart to pump blood to all parts of the body.
  • This helps in lowering blood pressure and the risk of having a heart attack or stroke.
  • Ramipril helps reduce both standing and lying down blood pressure without any orthostatic effect (a sudden decrease in blood pressure that can occur when a person stands up quickly). However, when dehydrated Ramipril may show an orthostatic effect.
  • Continued usage of Ramipril helps in decreasing the severity of heart failure, rate of hospitalization and symptoms such as weakness and shortness of breath.

Directions for Use

  • Ramipril can be taken with or without food.
  • It is usually taken once daily at the same time each day. However, your doctor may adjust the dosage and timing based on your medical condition and response to treatment.
  • Swallow Ramipril as a whole with a glass of water.
  • Do not crush or chew this medication.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Ramipril

  • Headache
  • Nausea
  • Dizziness
  • Weakness
  • Low blood pressure
  • Inflammation of the sinus (sinusitis)
  • Shortness of breath
  • Stomach pain
  • Diarrhoea
  • Indigestion

Drug Warnings

  • Do not take Ramipril if you are allergic to any of its contents.
  • Talk to your doctor if you have heart, kidney, or liver problems.
  • Ramipril may sometimes cause a lower decrease in blood pressure than normal, especially in dehydrated people, who are taking diuretics (medicines to treat edema) and have low levels of sodium.
  • Avoid taking Ramipril if you are pregnant or breastfeeding.
  • Talk to your doctor, he/she may prescribe you alternative medicine.
  • Ramipril is not recommended for children below 18 years of age as efficacy and safety have not been established.
  • Inform your doctor about all the medicines you are taking and about your health condition to rule out any unpleasant side effects.
  • Consult your doctor if you have lost a lot of body fluids through vomiting, diarrhoea or sweating more than normal or if you are taking low water tablets to treat oedema (diuretics), or if you undergo dialysis.
  • Inform your doctor that you are taking Ramipril if you are due to undergo any surgery or dental procedure; your doctor may advise you to stop taking Ramipril one day before receiving an anaesthetic to undergo any surgery or dental procedure.

Drug Interactions

Drug-Drug Interactions: Ramipril may interact with drugs used to treat severe heart failure (sacubitril/valsartan), pain killers (aspirin, naproxen and ibuprofen), PDE5 inhibitors (sildenafil), a drug used to treat gout (allopurinol), anti-diabetic (sitagliptin, metformin, insulin glargine), diuretics (furosemide), corticosteroid (prednisolone) and anti-convulsant (pregabalin).

Drug-Food Interactions: Maintain low salt and low-fat diet while taking Ramipril. Avoid consuming food rich in potassium such as potassium-containing salt substitutes or over-the-counter potassium supplements. Avoid smoking and alcohol consumption.

Drug-Disease Interactions: Inform your doctor if you have angioedema (swelling), congestive heart failure (heart problems), hemodialysis, low blood pressure, hyperkalemia (high levels of potassium in the body),  liver diseases and kidney dysfunction.

Drug-Drug Interactions Checker List:

  • PREGABALIN
  • ASPIRIN
  • NAPROXEN
  • IBUPROFEN
  • SILDENAFIL
  • ALLOPURINOL
  • SITAGLIPTIN
  • METFORMIN
  • INSULIN
  • FUROSEMIDE
  • PREDNISOLONE
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      You are recommended to avoid alcohol consumption while taking Ramipril to avoid unpleasant side-effects. Alcohol intake might interfere with the working of Ramipril. Please consult your doctor if you have any concerns regarding this.

    • Safety Warning

      Pregnancy

      unsafe

      It is not recommended to take Ramipril while you are pregnant. Please consult your doctor if you have any concerns regarding this.

    • Safety Warning

      Breast Feeding

      unsafe

      It is not recommended to take Ramipril while you are breastfeeding. Please consult your doctor if you have any concerns regarding this, your doctor will decide whether Ramipril can be given to breast-feeding mothers or not.

    • Safety Warning

      Driving

      unsafe

      Ramipril may cause dizziness, do not drive or operate heavy machinery if you feel dizzy.

    • Safety Warning

      Liver

      caution

      Dose adjustment may be needed. Ramipril should be used with caution in patients with liver impairment/liver disease.

    • Safety Warning

      Kidney

      caution

      Dose adjustment may be needed. Ramipril should be used with caution in patients with kidney impairment/kidney disease.

    • Safety Warning

      Children

      unsafe

      Ramipril should not be used by children as the efficacy and safety has not been established.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • You are advised to consume low salt and low-fat diet while taking Ramipril.
    • Regular exercise is also recommended to complement treatment with Ramipril.
    • Eat a diet rich in whole grains, vegetables, and fruits.
    • Avoid smoking and alcohol consumption.
    • Maintain a healthy weight with proper diet and exercise.
    • Managing stress with meditation, yoga, and massage would also help treat high blood pressure.

    Special Advise

    • Get up slowly while rising from a lying or sitting position, as Ramipril may cause dizziness.
    • Avoid consuming food rich in potassium, such as bananas, broccoli, almonds, avocado, and potassium supplements.
    • Regular monitoring of blood pressure, electrolyte levels, and kidney functioning is advised while taking Ramipril.

    Patients Concern

    Disease/Condition Glossary

    High blood pressure (hypertension): It is a condition in which the blood exerts increased pressure on the walls of blood vessels, leading to hypertension. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Raised blood pressure can cause chest pain (angina) and heart attack (when the blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. Symptoms of high blood pressure include headache, dizziness, nose bleed, changes in vision, chest pain, weakness and dyspnoea (shortness of breath). However, most of the time, the signs and symptoms of hypertension are none.

    FAQs

    Ramipril is used to treat high blood pressure (hypertension) and reduce the risk of heart attack, stroke or heart failure.

    Ramipril belongs to the group of medicines called Angiotensin Converting Enzyme (ACE) Inhibitors that works by lowering the body's production of substances that could increase the blood pressure. Ramipril relaxes and widens the blood vessels making it easier for the heart to pump blood to all parts of the body. This helps in lowering the blood pressure and the risk of having a heart attack or stroke.

    If you are diabetic you should monitor your blood glucose levels often especially in the first few weeks because Ramipril can lower glucose/sugar levels in blood. However, please consult your doctor before taking Ramipril if you are diabetic.

    Please do not stop taking Ramipril without consulting your doctor on your own as it may lead to rise in blood pressure. Continue taking Ramipril for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Ramipril.

    Orthostatic hypotension could be a side effect of Ramipril, especially in people who are dehydrated. Orthostatic hypotension is a sudden lowering in blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking, instead lie down and get up slowly only when you feel better. People taking Ramipril are advised to regularly monitor their blood pressure levels to avoid such unpleasant events.

    Available Medicines for

    Ramipril

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