Rabeprazole+itopride
About Rabeprazole+itopride
Rabeprazole+itopride is used to lower the increased level of stomach acid. It treats GERD (gastroesophageal reflux disease) and peptic ulcers. Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently flows back into the food pipe (esophagus). Peptic ulcers are sores that develop on the inner lining of the intestine and stomach.
Rabeprazole+itopride contains Rabeprazole and Itopride. Rabeprazole works by blocking the action of an enzyme called gastric proton pump, which is responsible for acid production. Itopride works on the part of the brain that is responsible for controlling vomiting.
Sometimes, you may experience common side effects such as headache, nausea, stomach pain, dizziness, and diarrhea. You are advised to talk to your doctor if you experience these side effects persistently.
Do not take Rabeprazole+itopride if you are allergic to any of its contents. Do not take Rabeprazole+itopride if you are pregnant or breastfeeding unless prescribed by the doctor. It should not be given to children, as safety has not been established.
Uses of Rabeprazole+itopride
Medicinal Benefits
- Rabeprazole+itopride is a combination of Rabeprazole and Itopride.
- Rabeprazole is a proton pump inhibitor (PPI) that works by blocking the action of an enzyme called the gastric proton pump, which is responsible for acid production.
- It minimises the release of acid from the stomach, which provides relief from heartburn and acid-related digestion.
- Itopride works on the part of the brain responsible for controlling vomiting.
- It increases gastric emptying and improves gastric sensitivity and tension by increasing the stomach's movement and intestines in the upper digestive tract. It also has antiemetic action.
Directions for Use
- Take Rabeprazole+itopride with or without food, or as advised by a doctor.
- Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
- Swallow the medicine as a whole with a glass of water.
- Do not crush, break, or chew it.
Storage
Side Effects of Rabeprazole+itopride
- Nausea
- Dizziness
- Diarrhea
- Headache
- Stomach pain
Drug Warnings
- Do not take Rabeprazole+itopride if you are allergic to any of its contents.
- Inform your doctor before taking Rabeprazole+itopride if you have a history of gastrointestinal bleeding, mechanical perforation/obstruction, or movement disorder.
- Do not take Rabeprazole+itopride if you are pregnant or breastfeeding unless prescribed by the doctor.
- Rabeprazole+itopride causes dizziness, so drive only if you are alert.
- Rabeprazole+itopride should not be given to children as safety has not been established.
- Avoid consuming alcohol along with Rabeprazole+itopride as it could lead to increased drowsiness and elevate stomach acid production.
- Keep your doctor informed about all the medicines and your health condition to rule out any side effects.
- Consult your doctor if you experience unexplained weight loss, stomach pain, indigestion, vomit food or blood, or if you pass black stools.
- On long-term treatment, Rabeprazole+itopride may cause osteoporosis and hypomagnesemia (low levels of magnesium), and may reduce the absorption of vitamin B12.
Drug Interactions
DRUG-DRUG INTERACTIONS: Rabeprazole+itopride may have interaction with pain killers (aspirin, naproxen), an antidepressant (duloxetine), hypothyroidism (levothyroxine), statins (atorvastatin), blood thinner (clopidogrel), and vitamin (vitamin b12).
FOOD-DRUG INTERACTIONS: Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
DRUG-DISEASE INTERACTION: Rabeprazole+itopride may have interactions with gastrointestinal bleeding, mechanical obstruction or perforation, Clostridium difficile-associated diarrhea (CDAD), liver disease, bone fractures, hypomagnesemia (low levels of magnesium).
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid consumption of alcohol while taking Rabeprazole+itopride. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
Pregnancy
consult your doctorConsult your doctor before taking Rabeprazole+itopride if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.
Breast Feeding
consult your doctorConsult your doctor before taking Rabeprazole+itopride; your doctor may prescribe this medicine if the benefits outweigh the risks.
Driving
cautionRabeprazole+itopride causes dizziness. Do not drive or operate machinery unless you are alert.
Liver
consult your doctorConsult your doctor before taking Rabeprazole+itopride if you have a liver impairment or any concerns.
Kidney
consult your doctorConsult your doctor before taking Rabeprazole+itopride if you have kidney impairment or any concerns.
Children
unsafeRabeprazole+itopride should not be given to children as safety and effectiveness were not established.
Habit Forming
Diet & Lifestyle Advise
- Eat smaller meals more often.
- Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
- Maintain a healthy weight through regular exercise.
- Avoid lying down after eating.
- Avoid tight-fitting clothes.
- Maintain a healthy weight through regular exercise.
- Practice relaxation techniques and avoid stress by doing yoga or meditation.
- Avoid foods such as high-fat, spicy chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea and soda.
- Avoid sitting continuously, as it may trigger acidity. Take a 5-minute break every hour by doing brisk walking or stretching.
Special Advise
- Inform your doctor before taking Rabeprazole+itopride if you are due to have a Chromogranin A test.
- Regular tests of magnesium and calcium are recommended if you are taking prescribed Rabeprazole+itopride regularly.
Patients Concern
Disease/Condition Glossary
Gastroesophageal reflux disease (GERD): GERD (Gastroesophageal Reflux Disease) is a chronic condition where stomach acid flows back into the oesophagus, causing heartburn and irritation. It often happens when the lower oesophagal sphincter doesn't close properly. Symptoms include heartburn, a sour or bitter taste, and difficulty swallowing.
Peptic ulcer: Peptic ulcers are sores that develop on the stomach and intestine lining due to erosion of the stomach's protective lining. Symptoms include nausea, changes in appetite, bloody or dark stools, unexplained weight loss, vomiting, and indigestion.
FAQs
Rabeprazole+itopride is used to treat GERD (gastro-esophageal reflux disease), and peptic ulcers.
Rabeprazole+itopride is a combination of two drugs: Rabeprazole and Itopride. Rabeprazole is a proton pump inhibitor (PPI), that works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid. It minimizes the release of acid from the stomach, which provides relief from heartburn and acid-related digestion. While Itopride works on the part of the brain responsible for controlling vomiting. It increases gastric emptying and improves gastric sensitivity and tension by increasing the movement of the stomach and intestines in the upper digestive tract. It also has antiemetic action. Together, Rabeprazole+itopride helps prevent acid reflux and provide relief from acidity.
Talk to your doctor if you do not feel better even after taking Rabeprazole+itopride for 14 days. Do not take Rabeprazole+itopride for longer durations unless prescribed by the doctor.
Diarrhea might be a side-effect of Rabeprazole+itopride. Drink enough fluids and eat fibre-rich food if you experience diarrhea. If you find blood in your stools (tarry stools) or if you experience excess diarrhea, consult your doctor. Do not take anti-diarrheal medicine on your own.
Avoid or limit the consumption of alcohol while taking Rabeprazole+itopride as it may lead to increased dizziness. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
Avoid lying down immediately after meals to prevent acid reflux. Raise the head of the bed 10-20cm by putting a pillow so that the head and chest are above the waist. This helps in preventing acid reflux.
Rabeprazole+itopride contains lactose monohydrate, so a person who is intolerant to sugar should tell their doctor before taking this medicine.
Consult your doctor before taking Rabeprazole+itopride if you are pregnant or planning for pregnancy. Your doctor will prescribe Rabeprazole+itopride only if the benefits outweigh the risks.
The common side effects of Rabeprazole+itopride include headache, nausea, stomach pain, dizziness, and diarrhea. If these side effects persist or worsen, please consult your doctor.
Take Rabeprazole+itopride at the time recommended by your doctor. It is usually best to take it 30 to 60 minutes before breakfast, as this helps the medication work effectively to reduce stomach acid.
Rabeprazole+itopride is contraindicated in people who are allergic to any of its components. Inform your doctor before taking Rabeprazole+itopride if you have a history of gastrointestinal bleeding, mechanical perforation or obstruction, or a movement disorder. Do not take Rabeprazole+itopride if you are pregnant or breastfeeding unless prescribed by a doctor.
Rabeprazole+itopride may cause dizziness as a side effect. If you feel dizzy after taking Rabeprazole+itopride, avoid driving or using machinery until you feel alert again. If the dizziness continues, please contact your doctor.
Rabeprazole+itopride contains rabeprazole (a proton pump inhibitor), which may increase the risk of fractures, particularly of the hip, wrist, and spine, when used long-term or in multiple daily doses, especially in older adults. This is primarily due to reduced calcium absorption. If you are using Rabeprazole+itopride for an extended period, monitor your bone health regularly (e.g., calcium levels, bone density) and talk to your doctor if you have any concerns.
Rabeprazole+itopride is not usually known to affect your ability to drive. However, if you experience side effects like dizziness or drowsiness after taking Rabeprazole+itopride, it is best to avoid driving.
Rabeprazole+itopride should be stored at room temperature, away from direct sunlight and moisture. Keep it out of reach of children.
