Olmesartan Medoxomil+amlodipine
About Olmesartan Medoxomil+amlodipine
Olmesartan Medoxomil+amlodipine is primarily used to treat high blood pressure. Hypertension or high blood pressure is a chronic condition in which the force of blood against the artery wall is high. As a result, it leads to heart disease, irregular heartbeat, and other complications.
Olmesartan Medoxomil+amlodipine contains Olmesartan and Amlodipine. Olmesartan works by blocking the hormone angiotensin, thereby relaxing blood vessels. Amlodipine, reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body.
In some cases, you may experience headaches, drowsiness, ankle swelling, nausea, dizziness, and low blood pressure, which gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.
Please inform your doctor if you are taking any other medications or have an allergy to Olmesartan Medoxomil+amlodipine. If you are pregnant or breastfeeding, please tell your doctor, as it is not recommended in pregnancy. It should not be given to children less than 12 years of age.
Uses of Olmesartan Medoxomil+amlodipine
Medicinal Benefits
- Olmesartan Medoxomil+amlodipine contains Olmesartan (angiotensin receptor blocker) and Amlodipine (calcium channel blocker).
- Olmesartan works by blocking the hormone angiotensin, thereby relaxing blood vessels. This allows the blood to flow more smoothly and the heart to pump more efficiently.
- Amlodipine, on the other hand, acts by relaxing the blood vessels. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body.
- Thus, both help lower high blood pressure, reducing future heart attack or stroke chances.
- Olmesartan Medoxomil+amlodipine is used alone or in combination with other blood pressure-lowering medications.
Directions for Use
- Olmesartan Medoxomil+amlodipine can be taken with or without food as advised by your doctor.
- Follow your doctor's instructions on the dosage and timing of this medication.
- Swallow Olmesartan Medoxomil+amlodipine as a whole with a glass of water.
- Do not crush, break, or chew it.
Storage
Side Effects of Olmesartan Medoxomil+amlodipine
- Headaches
- Drowsiness
- Ankle swelling
- Nausea
- Dizziness
- Low blood pressure
Drug Warnings
- Olmesartan Medoxomil+amlodipine should not be given to the people allergic to Olmesartan Medoxomil+amlodipine or may of its ingredients.
- If you have low blood pressure (less than 90 mm of Hg), have had a heart attack, kidney disease, liver disease or diabetes or planning to get pregnant and breastfeeding women; do not take Olmesartan Medoxomil+amlodipine.
- Besides this, it is contraindicated in low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart), and aortic stenosis (heart valve problem).
- Grapefruit juice and St. John's wort plant should not be consumed when taking Olmesartan Medoxomil+amlodipine as it is contraindicated.
- Drinking alcohol while using Olmesartan Medoxomil+amlodipine can cause you to have low blood pressure, so avoid alcoholic beverages.
- Reducing the amount of table salt (sodium chloride) in your food often relieves the body's swelling.
Drug Interactions
Drug-Drug Interactions: Olmesartan Medoxomil+amlodipine may interact with high blood pressure lowering pills (metoprolol, ramipril, hydrochlorothiazide), drugs used to control lipid levels in the blood (atorvastatin, simvastatin), medicines to treat erectile dysfunction (sildenafil), antibiotics (erythromycin, rifampin), antifungal (itraconazole, ketoconazole), anti-HIV drugs (ritonavir), anti-epilepsy medicines (carbamazepine, phenytoin, phenobarbital, primidone), immune-suppressing drugs (cyclosporine, tacrolimus) and painkillers (ibuprofen, aspirin).
Drug-Food Interactions: Olmesartan Medoxomil+amlodipine may interact with grapefruit, grapefruit juices, and St. John’s wort (a plant used to treat depression). Hence it should not be taken with Olmesartan Medoxomil+amlodipine.
Drug-Disease Interactions: Olmesartan Medoxomil+amlodipine should not be given to people with cardiogenic shock (when the heart fails to pump required blood to the body), heart valve problem (stenosis), low blood pressure (hypotension), liver disease, or heart failure.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeYou are recommended not to consume alcohol along with Olmesartan Medoxomil+amlodipine to avoid unpleasant side effects.
Pregnancy
cautionOlmesartan Medoxomil+amlodipine contains category C (amlodipine) and category D (olmesartan), as category D is a high risk, so it should not be taken during pregnancy.
Breast Feeding
unsafeOlmesartan Medoxomil+amlodipine is not recommended in breastfeeding mothers. It is excreted into milk in small amounts and is cleared slowly. It can accumulate in infants, especially newborns or preterm infants. Lactation might also be suppressed due to the effect of Olmesartan Medoxomil+amlodipine.
Driving
cautionDriving after taking Olmesartan Medoxomil+amlodipine is not recommended as it may occasionally cause drowsiness or fatigue.
Liver
cautionOlmesartan Medoxomil+amlodipine to be taken with caution, especially if you have a liver disease history. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.
Kidney
cautionOlmesartan Medoxomil+amlodipine to be taken with caution, especially if you have a history of kidney diseases. The dose may have to be adjusted by your doctor.
Children
unsafeUse of Olmesartan Medoxomil+amlodipine in children less than 12 years of age is not recommended as the safety and efficacy of Olmesartan Medoxomil+amlodipine in these age groups have not yet been established.
Habit Forming
Diet & Lifestyle Advise
- Keep your weight under control with a BMI of 19.5-24.9.
- Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help you to lower your raised blood pressure by about 5 mm of Hg.
- Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
- Limit sodium chloride (table salt) intake in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.
- If you are taking alcohol, then only one serving for women and two servings for men is advisable.
- Quitting smoking is the best strategy to lower the risk of heart disease.
- Avoid chronic stress, as it can raise your blood pressure. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques.
- Monitor your blood pressure daily and if there is too much fluctuation, then immediately contact your doctor.
- Try to include heart-healthy omega-3 fatty acids-containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to help lower your elevated blood pressure.
Patients Concern
Disease/Condition Glossary
High blood pressure: It is the measurement of the force that our heart uses to pump blood to all parts of the body. Hypertension is a chronic condition characterised by blood pressure that is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Raised blood pressure can cause chest pain (angina) and a heart attack (when blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor. Systolic pressure is the pressure with which the heart pumps blood out. Diastolic pressure occurs when your heart is at rest between heartbeats. If your blood pressure is 140/90 mmHg, it means the systolic pressure is 140 mmHg, and the diastolic pressure is 90 mmHg. The ideal blood pressure range should be between 90/60 mmHg and 120/80 mmHg.
FAQs
Olmesartan Medoxomil+amlodipine is used to treat Hypertension (high blood pressure).
No, you are advised to inform your doctor and monitor your blood pressure for at least two weeks before stopping the medicine. Depending upon your current blood pressure readings, there is a possibility your doctor may lower your medicine dosage and not recommend discontinuing it.
Olmesartan Medoxomil+amlodipine can be safely taken as long as your doctor prescribes it. Conditions such as high blood pressure are life-long conditions, and one should not abruptly discontinue it without discussing it with a doctor.
Olmesartan Medoxomil+amlodipine contains Olmesartan (angiotensin receptor blocker) and Amlodipine (calcium channel blocker). Olmesartan works by blocking the hormone angiotensin, thereby relaxing blood vessels. This allows the blood to flow more smoothly and the heart to pump more efficiently. Amlodipine, on the other hand, acts by relaxing the blood vessels. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, both help lower high blood pressure, reducing the chances of heart attack or stroke.
Yes, Olmesartan Medoxomil+amlodipine is contraindicated in people with known allergies to any of this medicine's components. It should be used with caution in people with liver impairment. It should also be avoided in women who are in the second and third trimesters of their pregnancy.
Unlikely that Olmesartan Medoxomil+amlodipine affects fertility in men or women. However, there's not enough evidence to say for certain. For the best advice, consult your doctor.
Yes, Olmesartan Medoxomil+amlodipine contains amlodipine, which is known to cause ankle swelling upon long-term use. Please try to keep your feet up when sitting for long hours. If the problem persists still, consult your doctor and do as advised.
High blood pressure during pregnancy is called Pregnancy-induced hypertension (PIH). It is harmful to both the baby and the mother. In the mother, very high blood pressure can cause seizures (fits), headache, swelling of the feet, kidney damage, and a higher risk of bleeding during pregnancy and delivery. This can also affect the baby by causing abnormal fetal heart rate, risk of stillbirth, and a small baby. So, during pregnancy, you should have regular blood pressure monitoring. Visit your Obstetrician if you have any concerns related to blood pressure during pregnancy.
Before starting Olmesartan Medoxomil+amlodipine, it's crucial to have a thorough consultation with your doctor. Share your comprehensive medical history, including any existing conditions or past illnesses. Also, provide a detailed list of your medications, vitamins, and supplements. Inform your doctor about any medication allergies or sensitivities. Additionally, discuss your lifestyle habits, such as smoking, alcohol consumption, or recreational drug use. If you're pregnant, breastfeeding, or planning to become pregnant, be sure to disclose this information. This will enable your doctor to determine whether Olmesartan Medoxomil+amlodipine suits you and provide personalized care.
Take Olmesartan Medoxomil+amlodipine precisely as prescribed by your doctor. The typical dosage is once daily, but your doctor may adjust the frequency based on your needs. To ensure effective treatment, follow your doctor's instructions regarding the best time of day to take Olmesartan Medoxomil+amlodipine. This may depend on your daily routine, other medications you're taking, and your medical condition. Be sure to ask your doctor if you have any questions or concerns about when to take Olmesartan Medoxomil+amlodipine.
After starting Olmesartan Medoxomil+amlodipine, you can expect to start feeling better within 8 hours as your blood pressure begins to decrease. Within 1 week, you will start to feel the full effects of Olmesartan, with your blood pressure lowering further. As Amlodipine reaches its full effect in 3-4 weeks, your blood vessels relax, and blood flow improves. Finally, within 2-8 weeks, you'll likely experience the maximum benefit, with your blood pressure well-controlled and any related symptoms improved, helping you feel your best.
It's important to take Olmesartan Medoxomil+amlodipine at the same time every day, as prescribed by your doctor. This helps maintain consistent levels of the medication in your body and ensures it works effectively. While you can take Olmesartan Medoxomil+amlodipine at any time of day, it's best to take it at a time that fits your daily routine.
In some cases, you may experience headaches, drowsiness, ankle swelling, nausea, dizziness, and low blood pressure. Most of these side effects of Olmesartan Medoxomil+amlodipine do not require medical attention and gradually resolve over time. However, if the side effects persist, contact your doctor.
While using Olmesartan Medoxomil+amlodipine, consider making lifestyle changes to help manage your blood pressure and overall health. Maintain a healthy weight, exercise for at least 30 minutes a day, and eat a balanced diet rich in whole grains, fruits, vegetables, and low-fat dairy products. Limit your sodium intake and alcohol consumption, and quit smoking if you haven't already. Manage stress through mindfulness practices and social support, and monitor your blood pressure daily. Additionally, include omega-3-rich foods in your diet and use low-fat oils like olive, soybean, canola, and coconut oil for cooking. Remember to consult your doctor for personalized advice on making these lifestyle changes to ensure you're taking the best care of your health.
Olmesartan Medoxomil+amlodipine may cause weight gain in some individuals, although it is not a common side effect. This is because Amlodipine can lead to fluid retention, while Olmesartan can increase potassium levels, resulting in increased water retention and weight gain. However, the weight gain is usually minimal. If you're concerned, your doctor can help you monitor your weight, adjust your diet and exercise routine, and explore alternative medications if needed.
The serious side effects of Olmesartan Medoxomil+amlodipine include bloating or swelling of the face, arms, hands, lower legs, or feet and rapid weight gain, which occurs more commonly. Less common serious side effects include fast, irregular, pounding, or racing heartbeat or pulse, and unusual tiredness or weakness. If you experience any of these side effects, seek medical attention immediately.
Olmesartan Medoxomil+amlodipine is unlikely to affect fertility or sex life in men or women. Still, the current evidence is insufficient to confirm this. To get personalized advice, consult your doctor.
Take Olmesartan Medoxomil+amlodipine exactly as prescribed by your doctor to manage your high blood pressure (hypertension). This is a long-term treatment, which means you'll need to take it continuously for an extended period. Regular check-ups with your doctor are crucial to monitor your blood pressure, adjust your dosage as needed, and ensure Olmesartan Medoxomil+amlodipine works effectively and safely for you. Following your doctor's instructions and attending regular check-ups can effectively manage your high blood pressure and reduce the risk of related health issues.
Take the missed dose as soon as you remember, unless it's almost time for your next dose. In this case, skip the missed dose and take your next dose at the regular time. Never take a double dose to make up for a missed one.
Do not consume alcohol along with Olmesartan Medoxomil+amlodipine to avoid unpleasant side effects. If you have any concerns regarding this consult your doctor.
If you notice side effects while taking Olmesartan Medoxomil+amlodipine, they will usually be mild and temporary and will go away on their own as your body adjusts. However, if the side effects are severe, persistent, or worsen over time, it's important to consult your doctor for personalized advice and care.
Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding. They will help you understand the potential risks and benefits of taking Olmesartan Medoxomil+amlodipine during this time. It's essential to prioritize your and your baby's health and well-being.
Consult your doctor or pharmacist before taking any other medicines while on Olmesartan Medoxomil+amlodipine. They will help you understand potential interactions and ensure safe combined use. Some medicines may interact with Olmesartan Medoxomil+amlodipine, so it's essential to disclose all medications, supplements, and vitamins you're taking to avoid potential adverse effects.
You can take Olmesartan Medoxomil+amlodipine with or without food. However, taking it with a meal is preferred to minimize stomach upset and dizziness. Taking it with food can help your body absorb the medication better.
The side effects of Olmesartan Medoxomil+amlodipine include headaches, drowsiness, ankle swelling, nausea, dizziness, and low blood pressure. Most of these side effects do not require medical attention and typically resolve on their own over time. However, if the side effects are persistent, contact your doctor.
