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Naproxen

About Naproxen

Naproxen is primarily used to reduce pain and swelling in muscles and joints in conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, cervical spondylitis and acute gout.

Naproxen contains Naproxen, which works by blocking the action of the cyclo-oxygenase (COX) enzyme in the body that is involved in the production of certain chemical substances, such as prostaglandins, that cause pain and swelling.

In some cases, you may experience indigestion, heartburn, stomach pain, nausea, headache, dizziness, drowsiness, bruising, itching, rash, and ringing in your ears. If the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Naproxen or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, please inform your doctor before taking Naproxen. Keep your doctor informed about your medical conditions and medications to prevent any interactions/side effects.

Uses of Naproxen

Naproxen is used in the treatment of joint pains, menstrual cramp. The detailed uses of Naproxen are as follows:
• Pain Relief: Naproxen is commonly used to alleviate mild to moderate pain, including headaches, toothaches, and muscle aches, providing relief and improving daily functioning.
• Anti-inflammatory: Naproxen is effective in reducing inflammation associated with conditions such as arthritis, helping to ease symptoms related to swelling and stiffness in the joints.
• Menstrual Discomfort: Naproxen can be used to treat dysmenorrhea, offering relief from menstrual cramps and associated discomfort during the menstrual cycle.
• Gout Attacks: Naproxen is often prescribed to manage pain and inflammation during acute gout attacks, helping to reduce the severity and duration of symptoms.
• Tendinitis and Bursitis: Naproxen is useful in the treatment of tendinitis and bursitis, providing relief from the pain and inflammation in the tendons and bursae around joints.

Medicinal Benefits

  • Naproxen is used to relieve pain, inflammation, and swelling in muscles and joints.
  • It is effective in treating various joint and musculoskeletal conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, cervical spondylitis, and acute gout.
  • It helps reduce pain and stiffness associated with these conditions, improving mobility and quality of life.
  • Naproxen is also beneficial in managing fibrositis (muscle pain and stiffness), tenosynovitis (inflammation of tendons), low back pain, and injuries such as strains and sprains.
  • By reducing inflammation and easing movement, Naproxen helps restore normal joint and muscle function.

Directions for Use

  • Naproxen can be taken with or after food to avoid stomach upset.
  • It is recommended to take Naproxen twice daily or as advised by your doctor.
  • Swallow Naproxen as a whole with a glass of water.
  • Do not crush, chew, or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Naproxen

  • Indigestion
  • Heartburn
  • Stomach pain
  • Constipation
  • Gas
  • Vomiting
  • Nausea
  • Diarrhoea

Drug Warnings

  • If you are allergic to Naproxen or any other medicines, please tell your doctor.
  • Pregnant or breastfeeding women are advised to consult a doctor before taking Naproxen.
  • Do not consume alcohol with Naproxen as it may increase the risk of stomach bleeding.
  • Naproxen may cause an increased risk of severe heart problems like myocardial infarction and stroke, which can be fatal.
  • If you notice bleeding from your back passage as black sticky motions or bloody stools, blood in vomit or stomach pain spreading to the back, please stop taking Naproxen and contact your doctor immediately.
  • It should not be used by the patient who has undergone recent heart bypass surgery or is about to undergo surgery.
  • Naproxen increases the risk of severe gastrointestinal conditions like bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal.
  • If you experience weight loss, diarrhoea, pain or vomiting, please stop taking Naproxen and consult a doctor immediately, as these might be signs of worsening Crohn’s disease or ulcerative colitis (swelling in the digestive tract).

Drug Interactions

Drug-Drug Interaction: Naproxen may have interaction with pain killers (ibuprofen, diclofenac, paracetamol, aspirin), high blood pressure-lowering medicines (propranolol, enalapril, cilazapril, losartan, candesartan, eprosartan), water pills (furosemide), blood thinners (heparin, warfarin, clopidogrel), fits related medicines (phenytoin), antidiabetic drugs (glimepiride, glipizide), antibiotics (moxifloxacin, ciprofloxacin), HIV/AIDS medicines (Zidovudine).

Drug-Food Interaction: Naproxen may interact with alcohol. Therefore, avoid alcohol intake while taking Naproxen as it may increase the risk of stomach bleeding.

Drug-Disease Interaction: People with diabetes, stomach ulcer, gastrointestinal bleeding, asthma, kidney, liver or heart problems and an autoimmune condition, such as systemic lupus erythematosus (joint pain, fever and skin rashes), colitis or Crohn’s disease (conditions causing swelling of the bowel, diarrhoea, bowel pain, vomiting and weight loss) should consult a doctor before taking Naproxen.

Drug-Drug Interactions Checker List:

  • IBUPROFEN
  • DICLOFENAC
  • PARACETAMOL
  • ASPIRIN
  • PROPRANOLOL
  • ENALAPRIL
  • CILAZAPRIL
  • LOSARTAN
  • CANDESARTAN
  • EPROSARTAN
  • FUROSEMIDE
  • HEPARIN
  • WARFARIN
  • CLOPIDOGREL
  • PHENYTOIN
  • GLIMEPIRIDE
  • GLIPIZIDE
  • MOXIFLOXACIN
  • CIPROFLOXACIN
  • ZIDOVUDINE
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      You are recommended to avoid consumption of alcohol with Naproxen as it may increase the risk of stomach bleeding and ulcer.

    • Safety Warning

      Pregnancy

      caution

      Naproxen is a Category C pregnancy drug and is considered unsafe for pregnant women, especially in the third trimester. However, please consult your doctor if you are pregnant.

    • Safety Warning

      Breast Feeding

      caution

      Avoid breastfeeding while taking Naproxen as it may be excreted in breast milk and cause adverse effects in the baby.

    • Safety Warning

      Driving

      caution

      Naproxen may cause dizziness, tiredness, drowsiness or vision problems in some people. So, drive only if you are alert after taking Naproxen.

    • Safety Warning

      Liver

      caution

      Take Naproxen with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

    • Safety Warning

      Kidney

      caution

      Naproxen is not recommended for use in patients with moderate to severe and severe renal impairment whose creatinine clearance is less than 30 mL/min. The dose may be adjusted by your doctor as required.

    • Safety Warning

      Children

      caution

      Naproxen can be prescribed to the children for the treatment of muscle/bone disorders for children (from 1 month), joint disease diseases (from 2 years) and for period pain in girl children (under 15 years). However, your doctor will decide whether Naproxen should be given for the specific condition or not.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Do regular exercise such as cycling, walking, jogging, dancing or swimming for a minimum of 30 minutes per day.
    • Maintain a healthy body weight (BMI between 18.5 - 24.9) as obesity may worsen joint pains and cause injury at the damaged site.
    • Maintain a low-fat and low-calorie diet and eat plenty of fruits and vegetables.
    • Avoid consumption of alcohol and quit smoking.

    Special Advise

    • If you are elderly, a smoker, have had a stroke previously, or have high blood pressure, diabetes or high cholesterol, please inform your doctor as these conditions may increase the risk of heart problems.
    • Do not take more than the prescribed dose as it may cause Naproxen overdose and lead to symptoms such as heartburn, stomach upset, unconsciousness, dizziness, ringing or buzzing in ears, fits, fainting, diarrhoea or excitation.

    Patients Concern

    Disease/Condition Glossary

    Arthritis: It is a condition that causes swelling of one or more joints, resulting in pain and stiffness of joints that worsen over time. There are different types of arthritis, of which osteoarthritis and rheumatoid arthritis are the most common types. The symptoms of arthritis include joint pain, stiffness, redness, tenderness, swelling in and around joints and reduced movement of joints. The risk of arthritis increases with age, obesity, previous joint injury or family history. Proper medication, physiotherapy or sometimes surgery may help to reduce symptoms of arthritis and enhance quality of life.

    FAQs

    Naproxen is used to reduce pain and swelling in muscles and joints in conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis (pain and stiffness in the backbone), cervical spondylitis (wear and tear of spinal discs in neck) and acute gout (severe pain due to excess of uric acid).

    Naproxen works by blocking the action of the cyclo-oxygenase (COX) enzyme in the body that is involved in the production of certain chemical substances, such as prostaglandins, that cause pain and swelling.

    Arthritis is a chronic condition of joints with pain and inflammation. Naproxen does not cure arthritis but relieve symptoms of arthritis like joint pain, swelling and stiffness.

    No, Naproxen is not recommended for use during pregnancy, especially in the last three months. It can affect and may harm the unborn baby (fetus). Therefore, if you are pregnant or planning for pregnancy, please inform your doctor before taking Naproxen.

    Yes, Naproxen may increase the risk of heart problems such as heart attack and stroke, especially when used in high doses or for prolonged duration. It is advised to inform your doctor if you have any of these conditions or have a history of heart problems or stroke before taking Naproxen. However, it is recommended to take Naproxen in doses and for the duration as prescribed by your doctor. It should not be used by the patient who has had recent heart bypass surgery (coronary artery bypass graft - CABG).

    Available Medicines for

    Naproxen

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