Metronidazole+rifaximin
About Metronidazole+rifaximin
Metronidazole+rifaximin is an antibiotic combination used to treat bacterial and gastrointestinal infections (including traveller's diarrhoea and irritable bowel syndrome). Gastrointestinal infections are conditions caused by harmful microorganisms, such as bacteria, viruses, or parasites, that affect the digestive system. They often lead to symptoms like nausea, vomiting, diarrhoea, and abdominal pain.
Metronidazole+rifaximin is a combination of Metronidazole and Rifaximin. Metronidazole is an antimicrobial agent that kills bacteria and protozoa by disrupting their DNA. Rifaximin is a non-absorbable antibiotic that works directly in the gut to inhibit bacterial growth. Together, they help relieve symptoms, prevent complications, and promote intestinal health.
Take Metronidazole+rifaximin for the duration your doctor prescribes, based on your medical condition. Some common side effects may include nausea, diarrhoea, abdominal pain, headache, dizziness, or a metallic taste. These effects are usually temporary and do not require medical attention. However, if they continue or worsen, see your doctor for advice.
Inform your doctor before using Metronidazole+rifaximin if you have a history of heart, liver/kidney disorder, colitis, blood dyscrasias, or neurologic toxicity. Avoid taking this medication during pregnancy or breastfeeding unless prescribed by your doctor. Avoid alcohol consumption while taking Metronidazole+rifaximin. Keep your doctor updated on your medications and health condition to prevent potential side effects.
Uses of Metronidazole+rifaximin
Medicinal Benefits
Metronidazole+rifaximin combines the benefits of two antibiotics to treat a variety of gastrointestinal and liver conditions. Metronidazole targets bacterial infections and helps treat conditions like gut infections, abscesses, and certain parasitic infections. Rifaximin, a non-absorbable antibiotic, is effective against bacterial overgrowth in the intestines and helps manage conditions like irritable bowel syndrome (IBS) and hepatic encephalopathy. Together, they support gut health, reduce bacterial infections, and improve overall digestive function.
Directions for Use
Swallow it as a whole with water; do not crush, break or chew it.
Storage
Side Effects of Metronidazole+rifaximin
- Nausea
- Diarrhea
- Headache
- Dizziness
- Abdominal pain
- Metallic taste
Drug Warnings
Avoid taking Metronidazole+rifaximin if you are allergic to any of its ingredients. Inform your doctor before using Metronidazole+rifaximin if you have a history of heart, liver/kidney disorder, colitis, blood dyscrasias, or neurologic toxicity. Avoid taking this medication during pregnancy or breastfeeding unless prescribed by your doctor. This medication should only be given to children if prescribed by a doctor. Avoid alcohol consumption while taking Metronidazole+rifaximin. Inform your doctor about any other medications or herbal supplements you are using before starting Metronidazole+rifaximin. Metronidazole+rifaximin can cause dizziness and vision disturbances, so exercise caution when driving or operating machinery.
Drug Interactions
Drug-Drug Interaction: Metronidazole+rifaximin may interact with antibiotics (clarithromycin, erythromycin), antiviral medicine (ritonavir, saquinavir), blood thinners (warfarin), heart or blood pressure medicine (amiodarone, quinidine, verapamil), asthma medication (albuterol), antidepressants (escitalopram), anticancer (busulfan).
Drug-Food Interaction: Avoid consuming alcohol with Metronidazole+rifaximin, as it may lead to symptoms such as stomach pain, vomiting, nausea, flushing, and headache. Please consult your doctor before drinking alcohol while using Metronidazole+rifaximin.
Drug-Disease Interaction: Inform your doctor before using Metronidazole+rifaximin if you have a history of heart, liver/kidney disorder, colitis, blood dyscrasias, or neurologic toxicity.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionAvoid consuming alcohol with Metronidazole+rifaximin, as it may lead to symptoms such as stomach pain, vomiting, nausea, flushing, and headache. Please consult your doctor before drinking alcohol while using Metronidazole+rifaximin.
Pregnancy
unsafeMetronidazole+rifaximin should not be taken if you are pregnant or planning to have a baby. If you become pregnant while taking Metronidazole+rifaximin, stop taking the medication and contact your doctor immediately. Metronidazole should not be given in the first trimester of pregnancy as it may cause harm to the fetus.
Breast Feeding
cautionLimited information is available on the use of Metronidazole+rifaximin in breastfeeding. If you are breastfeeding, inform your doctor before taking Metronidazole+rifaximin.
Driving
cautionMetronidazole+rifaximin may cause dizziness. Therefore, avoid driving if you feel dizzy after taking Metronidazole+rifaximin.
Liver
consult your doctorNo dose adjustment of Metronidazole+rifaximin is needed for patients with mild to moderate liver impairment. Please consult your doctor if you have any concerns.
Kidney
cautionMetronidazole+rifaximin should be taken with caution, especially if you have a history of kidney disease or conditions. Your doctor may need to adjust the dose accordingly.
Children
cautionIf you have any concerns regarding the use of Metronidazole+rifaximin for children, please consult a doctor.
Habit Forming
Diet & Lifestyle Advise
- Avoid alcohol to reduce the risk of side effects.
- Avoid consuming spicy or greasy foods that may irritate the stomach.
- Eat smaller, more frequent meals to reduce gastrointestinal discomfort.
- Limit high-fiber foods if you experience diarrhea.
- Rest and manage stress to support recovery.
- Include probiotics to maintain gut health.
Patients Concern
Disease/Condition Glossary
Traveller’s Diarrhea:Traveler's diarrhoea is a disorder characterized by frequent loose or watery faeces, which are often caused by consuming contaminated food or water while travelling. It is frequently caused by bacterial infections, such as Escherichia coli (E. coli), but viruses or parasites can also cause it.
Irritable Bowel Syndrome (IBS): IBS is a common digestive disorder characterized by symptoms such as abdominal pain, bloating, diarrhoea, and constipation.
FAQs
Metronidazole+rifaximin is an antibiotic used to treat bacterial infections, particularly those affecting the gastrointestinal tract, such as traveller's diarrhoea and irritable bowel syndrome.
Metronidazole+rifaximin is a combination of Metronidazole and Rifaximin. Metronidazole is an antimicrobial agent that kills bacteria and protozoa by disrupting their DNA. Rifaximin is a non-absorbable antibiotic that works directly in the gut to inhibit bacterial growth. Together, they help relieve symptoms, prevent complications, and promote intestinal health.
Consult your doctor before taking Metronidazole+rifaximin with other antibiotics to avoid drug interactions.
Drinking alcohol while taking Metronidazole+rifaximin may cause an unpleasant reaction, including symptoms like stomach pain, vomiting, nausea, flushing, and headache. Therefore, it is essential to avoid alcohol during treatment with Metronidazole+rifaximin.
Taking higher amounts than prescribed is ineffective and may result in negative effects. To ensure safe and effective use, follow your doctor's dosage instructions.
Common side effects include nausea, headache, dizziness, metallic taste, and diarrhea. If these side effects persist or worsen, seek immediate medical attention.
