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METOLAZONE

About

METOLAZONE belongs to the group of medicines called diuretics indicated in the treatment of oedema (fluid retention) caused by kidney disease or heart failure. Additionally, it is also used alone or in combination with other medicines to treat high blood pressure. 

METOLAZONE contains Metolazone, which works by causing the kidneys to reduce the amount of water and salt in the body by increasing the amount of urine. Thereby, it helps reduce fluid retention and lowers blood pressure.

In some cases, METOLAZONE may cause side effects such as nausea, vomiting, diarrhoea, and constipation. Most of these side effects may not require medical attention and resolve gradually over time. However, you are advised to talk to the doctor if the side effects persist or worsen.

Do not take METOLAZONE if you are allergic to any of its components or if you are pregnant or breastfeeding. METOLAZONE is not recommended for children below 18 years. Keep the doctor informed about your health condition and medications to rule out any unpleasant side effects/interactions.

Uses of METOLAZONE

Treatment of oedema (fluid retention) and hypertension (high blood pressure).

Medicinal Benefits

METOLAZONE contains Metolazone, which is indicated in the treatment of oedema (fluid retention) accompanying congestive heart failure or renal diseases. Besides this, it is also used alone or in combination with other medicines to treat high blood pressure. METOLAZONE causes the kidneys to reduce the amount of water and salt in the body by increasing the amount of urine. Thereby, it helps reduce fluid retention and lowers blood pressure.

Directions for Use

Swallow the medicine as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of METOLAZONE

  • Nausea
  • Vomiting
  • Diarrhoea
  • Constipation
  • Headache
  • Dizziness
  • Muscle pain
  • Fatigue

In-Depth Precautions and Warning

Drug Warnings

Do not take METOLAZONE if you are allergic to any of its components, if you have anuria (unable to urinate), hepatic precoma or coma, or if you are pregnant or breastfeeding. Inform the doctor if you have liver or kidney problems, fluid or electrolyte imbalance, Addison’s disease (syndrome due to low level of corticosteroid hormones secretion), diabetes, gout (high levels of uric acid in the blood), systemic lupus erythematosus (an inflammatory disease of connective tissue), porphyria, eye pain or vision problems, or high cholesterol. Let the doctor know if you are taking any other medicines, including supplements or herbal products.

Drug Interactions

Drug-Drug Interactions: Inform the doctor if you are taking a muscle relaxant (tubocurarine), immunosuppressant (cyclosporine), cardiac glycoside (digoxin), antiarrhythmic (sotalol), painkillers, anticoagulants, antimanic agents (lithium) or anti-infectives (methenamine).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform the doctor if you have anuria (unable to urinate), hepatic coma or precoma, electrolyte losses, or severe liver/kidney disease.

Drug-Drug Interactions Checker List:

  • TUBOCURARINE
  • CYCLOSPORINE
  • DIGOXIN
  • SOTALOL
  • LITHIUM
  • METHENAMINE
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      Consuming alcohol in combination with METOLAZONE may cause a decrease in blood pressure, leading to dizziness and fatigue. Therefore, avoid alcohol consumption during treatment with METOLAZONE.

    • Safety Warning

      Pregnancy

      unsafe

      METOLAZONE is not recommended during pregnancy. Consult the doctor if you are pregnant, think you may be pregnant or planning for pregnancy.

    • Safety Warning

      Breast Feeding

      unsafe

      METOLAZONE is not recommended during breastfeeding. Consult the doctor if you are breastfeeding.

    • Safety Warning

      Driving

      caution

      METOLAZONE may cause dizziness and fatigue. Avoid driving or operating heavy machinery if you experience these symptoms.

    • Safety Warning

      Liver

      consult your doctor

      Please consult the doctor if you have liver problems or any concerns regarding this.

    • Safety Warning

      Kidney

      caution

      METOLAZONE should be used with caution in patients with severe renal impairment. Please consult the doctor if you have kidney problems or any concerns regarding this.

    • Safety Warning

      Children

      unsafe

      METOLAZONE is not recommended for children below 18 years as safety and effectiveness have not been established.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Follow a low-salt and low-fat diet. 
    • Exercise regularly for at least 30 minutes on most days.
    • Eat a diet rich in whole grains, vegetables, and fruits.
    • Avoid smoking and alcohol consumption.
    • Maintain a healthy weight with proper diet and exercise.
    • Manage stress with meditation, yoga, and massage.

    Special Advise

    If you are due to undergo any surgery or laboratory tests, inform the doctor that you are taking METOLAZONE.

    Patients Concern

    Disease/Condition Glossary

    Oedema: Oedema is a build-up of fluid in the body which causes the affected tissue to become swollen. It can occur due to immobility, certain medical conditions and medications. 

    High blood pressure (hypertension): It is a condition in which the blood exerts increased pressure on the walls of blood vessels, leading to hypertension. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Raised blood pressure can cause chest pain (angina) and heart attack. Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. Symptoms of high blood pressure include headache, dizziness, nose bleed, changes in vision, chest pain, weakness and dyspnoea (shortness of breath). However, most of the time, the signs and symptoms of hypertension are none.

    FAQs

    METOLAZONE is used to treat fluid retention (oedema) and high blood pressure (hypertension).

    METOLAZONE helps the kidneys remove water from the body and lower blood pressure.

    Please do not stop taking METOLAZONE without consulting your doctor. To treat your condition effectually, continue taking METOLAZONE for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking METOLAZONE.

    METOLAZONE may make your skin sensitive to sunlight. Therefore, avoid prolonged or unnecessary sun exposure. Wear protective clothing and use sunscreen whilst going out.

    METOLAZONE may cause light-headedness, dizziness, and fainting when you get up too quickly from a lying position. To prevent this, get out of bed slowly, resting your feet on the floor for a few minutes before standing up.

    Available Medicines for

    METOLAZONE

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