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Lidocaine+prilocaine

About Lidocaine+prilocaine

Lidocaine+prilocaine is used to produce local numbness (anaesthesia) on the skin before surgical procedures or injections. Pain is a symptom triggered by the nervous system, which causes uncomfortable sensations in the body. Pain may be dull or sharp, constant or intermittent, and the tolerance level of pain might vary from person to person.

Lidocaine+prilocaine is a combination of amide-type local anaesthetics: Lidocaine and Prilocaine. Lidocaine+prilocaine blocks the influx (entry) of sodium ions into the membrane that surrounds the nerves, thereby preventing the initiation and conduction of impulses. Hence, it gives an anaesthetic effect and helps decrease the sensation of pain.

Use Lidocaine+prilocaine as suggested by your doctor. Do not apply it to broken, irritated skin or open wounds unless directed by your doctor. In some cases, you may experience certain common side effects, such as reactions at the application site (burning, itching, redness, and irritation). Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Before using Lidocaine+prilocaine, tell your doctor about your medical history, especially if you have broken skin/infection in the area where Lidocaine+prilocaine is to be applied, heart disease, liver disease, or a certain blood disorder (methemoglobinemia). Inform your doctor before using Lidocaine+prilocaine if you plan to get pregnant, are pregnant or breastfeeding. If Lidocaine+prilocaine comes in contact with the eyes, nose, mouth, rectum, or vagina, rinse with water immediately. Do not apply Lidocaine+prilocaine on the swollen skin areas or deep puncture wounds. Inform your doctor about your health condition and medications before using Lidocaine+prilocaine to rule out any side effects.

Uses of Lidocaine+prilocaine

Treatment of Pain (during surgical procedures and injections)

Medicinal Benefits

Lidocaine+prilocaine is a combination of amide-type local anaesthetics, namely, Lidocaine and Prilocaine. It is used to produce local numbness (anaesthesia). It is used to numb the normal, unbroken skin or the outer genital area to prevent pain before surgical procedures such as inserting a needle, skin grafts, or skin laser surgery. It works by blocking the transmission of nerve signals in the body, thereby helping to decrease the sensation of pain.

Directions for Use

It should be applied to intact skin before the surgical procedure. Apply a thin layer with clean and dry hands on the skin. You can also apply it with a piece of clean cotton wool or a gauze swab. Gently rub the medicine into the skin until it has disappeared. Wash your hands thoroughly before and after using it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Lidocaine+prilocaine

  • ​​​​​​Itching
  • Rash
  • Mild burning at the site of the application
  • Changes in skin colour at the site of application

Drug Warnings

Use the recommended dose of Lidocaine+prilocaine to numb the skin. Do not exceed the dose and duration or cover treated skin areas with a bandage without the doctor's advice. In some cases, Lidocaine+prilocaine can cause fatal side effects such as uneven heartbeats, seizure (convulsions), coma, slowed breathing or respiratory failure (breathing stops), if too much of the medicine is absorbed through the skin. Consult your doctor before using Lidocaine+prilocaine if you are pregnant or breastfeeding, your doctor will prescribe you Lidocaine+prilocaine only if the benefits outweigh the risks. Lidocaine+prilocaine causes drowsiness, so drive with caution. Avoid consuming alcohol along with Lidocaine+prilocaine as it could lead to increased drowsiness. Lidocaine+prilocaine may not be suitable for people with a blood disorder, glucose-6-phosphate dehydrogenase (G6PD) deficiency, kidney or liver problems. Inform your doctor about your health condition and medications before using Lidocaine+prilocaine to rule out any side effects.

Drug Interactions

Drug-Drug Interaction: Lidocaine+prilocaine may interact with antimalarial drugs (chloroquine, quinine), medicines used to treat seizures (fits) (phenobarbital, phenytoin, primaquine), heart rhythm and blood pressure-lowering medication (amiodarone, dofetilide, dronedarone, mexiletine, sotalol, tocainide, nitroprusside, nitroglycerin, isosorbide), and antibiotics (nitrofurantoin).

Drug-Food Interaction: Avoid consuming alcohol along with Lidocaine+prilocaine as it could lead to increased drowsiness.

Drug-Disease Interaction: Lidocaine+prilocaine may interact with a blood disorder, heart dysfunction, liver problems and kidney dysfunction.

Drug-Drug Interactions Checker List:

  • CHLOROQUINE
  • QUININE
  • PHENOBARBITAL
  • PHENYTOIN
  • PRIMAQUINE
  • AMIODARONE
  • DOFETILIDE
  • DRONEDARONE
  • MEXILETINE
  • TOCAINIDE
  • SOTALOL
  • NITROPRUSSIDE
  • NITROGLYCERIN
  • ISOSORBIDE DINITRATE
  • NITROFURANTOIN
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      You are recommended to avoid alcohol consumption while using Lidocaine+prilocaine. Alcohol intake, along with Lidocaine+prilocaine, may cause increased drowsiness.

    • Safety Warning

      Pregnancy

      caution

      Lidocaine+prilocaine is pregnancy category B drug. If a lady is pregnant, they can use the medicine only after the doctor's recommendation. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe you Lidocaine+prilocaine only if the benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      caution

      Lidocaine+prilocaine can only be used in breastfeeding mothers after the doctor's suggestion.

    • Safety Warning

      Driving

      caution

      Lidocaine+prilocaine may cause drowsiness; do not drive or operate heavy machinery if you feel drowsy.

    • Safety Warning

      Liver

      caution

      Lidocaine+prilocaine should be used with caution in patients with liver impairment/liver disease. Dose adjustment may be needed. Please consult your doctor if you have a liver impairment or any concerns regarding this.

    • Safety Warning

      Kidney

      caution

      Lidocaine+prilocaine is safe if prescribed by a doctor in patients with serious kidney disease. Please ask your doctor about all of your liver problems.

    • Safety Warning

      Children

      caution

      Lidocaine+prilocaine is to be used on children only when prescribed by the doctor.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • ​​​​​​Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
    • Get adequate sleep, as resting the muscles can help reduce inflammation and swelling.
    • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
    • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
    • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
    • Avoid smoking and alcohol consumption.

    Special Advise

    • Do not apply near eyes or open wounds.
    • Inform your doctor immediately if you develop blistering of the skin where the medication is applied.

    Patients Concern

    Disease/Condition Glossary

    Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain may be dull or sharp; it might be constant or intermittent. The tolerance level of pain might vary from person to person. Pain can be generalized (overall body aches) or localized (affecting a specific body area). Pain can be considered a good thing as it helps us know something is wrong in the body and helps diagnose the condition. The common causes of pain include headache, muscle strain, cramps, cuts, bone fractures, arthritis, stomach aches, etc.

    FAQs

    Lidocaine+prilocaine belongs to the class of local anaesthetics known as 'numbing medication' used to produce local numbness (anaesthesia) on the skin before surgical procedures or injections.

    Lidocaine+prilocaine contains Lidocaine and Prilocaine. Together, Lidocaine+prilocaine works by blocking pain signals from the nerves to the brain, decreasing the sensation of pain.

    Do not use Lidocaine+prilocaine after expiry. Expiry refers to the last date that the manufacturer guarantees the full potency and safety of the drug. Check the expiry date from time to time and properly discard the Lidocaine+prilocaine after expiry or return it to your pharmacist for proper disposal.

    Be careful and check that no injury occurs in the numb area. You will not feel the pain, but it will hurt you the most after the action of Lidocaine+prilocaine ends.

    A person of age 65 or older should use Lidocaine+prilocaine with caution, as directed by the doctor, as the chances of side effects increase in older people.

    Available Medicines for

    Lidocaine+prilocaine

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