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Levobunolol

About Levobunolol

Levobunolol belongs to a class of ophthalmic preparations called anti-glaucoma agents primarily used to treat increased pressure in the eyes. Glaucoma is an eye condition that causes damage to the optic nerve (essential for good vision) due to abnormally increased pressure in the eye. Ocular hypertension is increased pressure in the eye due to poor drainage of aqueous humour (fluid in the eye that maintains normal pressure by its continuous flow).

Levobunolol contains Levobunolol, which is a beta-blocker. It works by blocking beta-receptors located in the eyes and decreasing the secretion of aqueous humour (fluid of eyeball that maintains eye pressure), thereby lowering the raised eye pressure. Thus, it prevents eyes from getting blind due to glaucoma and raised eye pressure. 

Use Levobunolol as prescribed. Levobunolol is only for use in eyes. You are advised to use Levobunolol for as long as your doctor has prescribed it based on your medical condition. In some cases, you may experience redness, itching, irritation or pain in the eyes, swelling of eyelids, blurred vision and dry eyes. Most of these side effects of Levobunolol do not require medical attention and gradually resolve over time. However, if the side effects worsen or persist, please consult your doctor.

If you are allergic to Levobunolol or any other medicines, please tell your doctor. Levobunolol is not recommended for children below 18 years of age. You are not advised to use Levobunolol if you are pregnant or breastfeeding unless prescribed by a doctor. You are advised to remove soft contact lenses before using Levobunolol as it may cause discolouration of the soft contact lens. If you get any new eye problem, an eye infection or notice any allergic reactions such as itching or redness of the eye and skin rash, please consult your doctor immediately. You are advised to maintain a 10 minutes time gap between using Levobunolol and other eye drops. Please do not touch the container tip to the eye, eyelids or surrounding areas as it may contaminate Levobunolol and cause eye infections. If you have asthma, chronic obstructive pulmonary disease (COPD), Raynaud’s disease or Raynaud’s syndrome (poor blood circulation), diabetes, hyperthyroidism (overactive thyroid gland), irregular heartbeat, heart failure or any other heart problems, inform your doctor before taking Levobunolol. 

Uses of Levobunolol

Treatment of Glaucoma, Ocular hypertension.

Medicinal Benefits

Levobunolol contains Levobunolol used to treat increased pressure in the eye in conditions such as glaucoma (damage of optic nerve) and ocular hypertension (high fluid pressure inside the eye). Levobunolol blocks beta-receptors on the ciliary body (part of the eye that produces aqueous humour). It decreases the secretion of aqueous humour (a liquid that maintains normal pressure in the eyeball) by the ciliary body into the eyeball. Thereby lowers the pressure in the eye by reducing aqueous humour entry into the eyeball.

Directions for Use

Levobunolol is only for use in the eyes. Do not swallow or inject Levobunolol. Lie down and tilt your head backward. Pull your lower eyelid gently with your index finger to form a pocket. Instill the number of drops as advised by the doctor into the pocket of the lower eyelid. Close your eyes for 1-2 minutes. Please do not touch the container tip to the eye, eyelids or surrounding areas as it may contaminate Levobunolol and cause eye infections.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Levobunolol

  • Redness, itching, irritation or pain in the eyes
  • Swelling of eyelids
  • Blurred vision
  • Dry eyes

Drug Warnings

If you are allergic to Levobunolol or any other medicines, please tell your doctor. Levobunolol is not recommended for children below 18 years of age. You are not advised to use Levobunolol if you are pregnant or breastfeeding unless prescribed by a doctor. You are advised to remove soft contact lenses before using Levobunolol as it may cause discolouration of the soft contact lens. If you get any new eye problem, an eye infection or notice any allergic reactions such as itching or redness of the eye and skin rash, please consult your doctor immediately. You are advised to maintain a 10 minutes time gap between using Levobunolol and other eye drops. Please do not touch the container tip to the eye, eyelids or surrounding areas as it may contaminate Levobunolol and cause eye infections. In very rare cases, you may notice cloudy patches on the cornea (transparent layer at the front of the eye) due to the accumulation of calcium as Levobunolol contains phosphates responsible for causing such severe damage to the cornea. If you have asthma, chronic obstructive pulmonary disease (COPD), Raynaud’s disease or Raynaud’s syndrome (poor blood circulation), diabetes, hyperthyroidism (overactive thyroid gland), irregular heartbeat, heart failure or any other heart problems, inform your doctor before taking Levobunolol.

Drug Interactions

Drug-Drug Interaction: Levobunolol may have interaction with high blood pressure-lowering medicines (amlodipine), medicines used to treat irregular heartbeat (digoxin, amiodarone), antidiabetic drugs and medicines to dilate the pupil (adrenaline).

Drug- Food Interaction: No interactions found.

Drug-Disease Interaction: If you have asthma, chronic obstructive pulmonary disease (COPD), Raynaud’s disease or Raynaud’s syndrome (poor blood circulation), diabetes, hyperthyroidism (overactive thyroid gland), irregular heartbeat, heart failure or any other heart problems, inform your doctor before taking Levobunolol.

Drug-Drug Interactions Checker List:

  • AMLODIPINE
  • DIGOXIN
  • AMIODARONE
  • ADRENALINE
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      The interaction of alcohol with Levobunolol is unknown. Please consult a doctor before consuming alcohol with Levobunolol.

    • Safety Warning

      Pregnancy

      unsafe

      Levobunolol is a Category C pregnancy drug and is not recommended for use during pregnancy unless your doctor considers it essential.

    • Safety Warning

      Breast Feeding

      unsafe

      Avoid breastfeeding while taking Levobunolol. Please consult a doctor before using Levobunolol in breastfeeding mothers.

    • Safety Warning

      Driving

      caution

      Levobunolol may cause blurred vision, dizziness or tiredness in some people. Therefore, drive only when your vision is clear and are alert after taking Levobunolol.

    • Safety Warning

      Liver

      caution

      If you have any concerns regarding the use of Levobunolol in patients with liver problems, please consult a doctor.

    • Safety Warning

      Kidney

      caution

      If you have any concerns regarding the use of Levobunolol in patients with kidney problems, please consult a doctor.

    • Safety Warning

      Children

      unsafe

      Levobunolol is not recommended for children below 18 years of age, as the safety and effectiveness were not established.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Avoid baked foods such as cakes, cookies, donuts or fried items such as French fries and stick margarine as these foods may worsen glaucoma and damaged the optic nerve.
    • Please cut down your coffee intake as it may increase pressure in the eye and replace coffee with green tea.
    • Avoid exercises such as any position where the head is lower than the body like inverted yoga pose as it may increase pressure in the eye. Doing selective exercises is advised for glaucoma patients.

    Special Advise

    • You are advised to inform your doctor before any operation that you are using Levobunolol as it may alter the effects of some medicines used during anesthesia.
    • Your doctor may monitor eye pressure after 4 weeks of starting treatment with Levobunolol.
    • Levobunolol may make it harder to tell if you have signs of an overactive thyroid like a fast heartbeat. So, if you have an overactive thyroid (hyperthyroidism) and have stopped taking Levobunolol all of a sudden, it may be life-threatening. 

    Patients Concern

    Disease/Condition Glossary

    Glaucoma: It is an eye condition that causes damage to the optic nerve (essential for good vision) due to abnormally increased pressure in the eye. If it is not treated in time, it may cause blindness. Usually, there are no symptoms of glaucoma initially except the slow loss of vision gradually. However, some symptoms include visible rainbow-colored circles around bright lights or blurred vision. Rarely, glaucoma can develop suddenly with intense pain in the eye, visual disturbance, or nausea.

    Ocular hypertension: It is a condition caused due to poor drainage of aqueous humor (fluid in the eye that maintains normal pressure by its continuous flow). This leads to the building up of excess fluid in the eye, resulting in increased pressure inside the eye without any damage to the optic nerve. If ocular hypertension is not controlled, it may lead to glaucoma.

    FAQs

    Levobunolol is used to treat increased pressure in the eyes.

    Levobunolol contains Levobunolol that works by blocking beta-receptors on the ciliary body (part of the eye that produces aqueous humour) and decreases the secretion of aqueous humour (a liquid that maintains normal pressure in the eyeball) by the ciliary body into the eyeball. Thereby lowers the pressure in the eye by reducing aqueous humour entry into the eyeball.

    No, you are not recommended to wear contact lenses while using Levobunolol as it contains benzalkonium chloride, a preservative that changes the colour of the contact lens as it may be absorbed by a soft contact lens. Benzalkonium chloride also causes irritation in the eye especially if you have disorders of the cornea (transparent layer at the front of the eye) or dry eyes. Therefore, you are advised to remove contact lenses before applying Levobunolol and reinsert after 15 minutes of using Levobunolol.

    You are recommended to maintain a minimum of 10 minutes time gap between using Levobunolol and other eye drops and administer eye ointments in the last.

    Yes, Levobunolol may cause temporary blurred vision. Therefore, you are recommended to wait until your vision is clear before driving or operating heavy machinery.

    You may need to stop using Levobunolol before surgery as it may alter the effects of certain medicines used during anaesthesia. Therefore, you are recommended to inform your doctor or dentist that you are using Levobunolol before any surgery or dental procedure.

    Levobunolol is not recommended for asthma patients as it may cause bronchoconstriction (narrowing of airways). However, it is advised to inform your doctor if you have asthma before taking Levobunolol.

    Pull your lower eyelid gently with your index finger to form a pocket. Instil the number of drops as advised by the doctor into the pocket of the lower eyelid. Close your eyes for 1-2 minutes. Please do not touch the container tip to the eye, eyelids or surrounding areas as it may contaminate Levobunolol and cause eye infections.

    Yes, Levobunolol is effective if used as per the dose duration advised by the doctor. Do not exceed the recommended dose. Continue using Levobunolol for the prescribed duration. Follow your doctor’s instructions.

    No, do not stop using Levobunolol even if you feel better. Stopping Levobunolol early without consulting your doctor can lead to a return of symptoms or a worsening of your condition, especially in the case of glaucoma or ocular hypertension. Therefore, complete the full course of treatment as prescribed by your doctor.

    Levobunolol should be avoided if you are allergic to it. Patients with asthma or severe chronic obstructive pulmonary disease (COPD) should avoid using Levobunolol due to the risk of worsening respiratory conditions. Also, avoid using Levobunolol if you have any heart problems. It is not recommended for use in children under 18 years of age. Also if you are breastfeeding, pregnant or planning pregnancy, avoid using Levobunolol unless recommended by your doctor.

    Store Levobunolol at a temperature not exceeding 30°C in a cool and dry place. Protect from light. Close the cap of Levobunolol tightly after each usage to prevent contamination. Keep out of reach of children.

    The common side effects of Levobunolol are redness, itching, irritation or pain in the eyes, swelling of eyelids, blurred vision and dry eyes. If any of these side effects persist or worsen, please consult your doctor.

    Available Medicines for

    Levobunolol

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