Isosorbide Dinitrate+hydralazine
About Isosorbide Dinitrate+hydralazine
Isosorbide Dinitrate+hydralazine belongs to a group of medicines called vasodilators used to treat heart failure. Heart failure occurs when the heart muscle does not pump blood normally, including shortness of breath, swollen legs, fatigue and increased heartbeat. In this condition, the heart becomes too weak and cannot pump enough blood and oxygen to the organs and tissues of the body.
Isosorbide Dinitrate+hydralazine contains Isosorbide dinitrate and Hydralazine. Isosorbide dinitrate relaxes the heart's muscles and widens the heart's veins and arteries for easy flow of blood to every part of the body. Hydralazine helps lower raised blood pressure by relaxing and widening the heart's muscles. Together, Isosorbide Dinitrate+hydralazine helps treat heart failure.
Take Isosorbide Dinitrate+hydralazine as your doctor has prescribed it. In some cases, Isosorbide Dinitrate+hydralazine can cause side effects like headache, nausea, dizziness, and lightheadedness (feeling faint). Most of these side effects of Isosorbide Dinitrate+hydralazine do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.
If you are known to be allergic to Isosorbide Dinitrate+hydralazine or any other medicines, please inform your doctor. Before taking Isosorbide Dinitrate+hydralazine, let your doctor know if you have had a heart attack within the last 30 days, low blood pressure, stroke (inadequate blood supply in the brain that causes damage to the brain), or high pressure within the brain. Please do not stop taking Isosorbide Dinitrate+hydralazine on your own, as it may lead to the recurrence of symptoms or worsen the condition.
Uses of Isosorbide Dinitrate+hydralazine
Medicinal Benefits
Isosorbide Dinitrate+hydralazine belongs to a group of vasodilators used to treat heart failure. Isosorbide Dinitrate+hydralazine contains Isosorbide dinitrate and Hydralazine. Isosorbide dinitrate belongs to a group of drugs known as nitrates. Isosorbide dinitrate relaxes the heart's muscles and stretches or enlarges the heart's veins and arteries. Hydralazine belongs to a group of drugs known as vasodilators, which help lower raised blood pressure by relaxing and widening the heart's blood vessels.
Directions for Use
Storage
Side Effects of Isosorbide Dinitrate+hydralazine
- Headache
- Nausea
- Dizziness
- Lightheadedness (feeling faint)
Drug Warnings
Do not take Isosorbide Dinitrate+hydralazine if you have low blood pressure because even a low dose of Isosorbide Dinitrate+hydralazine may produce low blood pressure. If you are pregnant or planning any pregnancy, let your doctor know about this before taking Isosorbide Dinitrate+hydralazine as it crosses the placenta and can affect the unborn baby (fetus). Do not drive by using this Isosorbide Dinitrate+hydralazine because it produces dizziness that may cause an accident. You may experience tingling or numbness, so your doctor may prescribe a vitamin B6 supplement (pyridoxine). Hydralazine passes into breast milk, so its use in lactating mothers should be avoided.
Drug Interactions
Drug-Drug Interactions: Care should be exercised when Isosorbide Dinitrate+hydralazine is administered in combination with migraine headache medicines (ergotamine), drugs used to treat erectile dysfunction (inability to get enlarged penis) (sildenafil, tadalafil), pain killers (ibuprofen, naproxen).
Drug-Food Interactions: No interactions found/established.
Drug-Disease Interactions: Isosorbide Dinitrate+hydralazine may interact with disease conditions, including hypotension (low blood pressure) and erectile dysfunction (inability to get an enlarged penis).
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionConsuming alcohol with the Isosorbide Dinitrate+hydralazine is not advisable as it may cause unpleasant side effects, or you may become more sensitive to the effects of alcohol.
Pregnancy
cautionIsosorbide Dinitrate+hydralazine is not recommended during pregnancy. Please discuss with the doctor if you have any concerns.
Breast Feeding
cautionIsosorbide Dinitrate+hydralazine is not recommended during nursing. Please discuss with the doctor if you have any concerns.
Driving
cautionIsosorbide Dinitrate+hydralazine may cause dizziness in some people, so it may affect your ability to drive.
Liver
cautionIsosorbide Dinitrate+hydralazine to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.
Kidney
cautionIsosorbide Dinitrate+hydralazine to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.
Children
cautionThe safety and effectiveness of Isosorbide Dinitrate+hydralazine in children have not been established.
Habit Forming
Diet & Lifestyle Advise
- Follow a cholesterol-lowering diet.
- Consume low salt and a low-fat diet.
- Exercise regularly. It helps in maintaining proper weight and lowers cholesterol.
- Limit salt and sugar intake.
- Avoid smoking and alcohol consumption.
- Choose healthy fats and cut down on trans fat.
- Include omega-3 fatty acids, fibre-rich food, fruits, and vegetables.
- Get active by doing physical activities such as swimming, brisk walking, or jogging. Take the stairs instead of elevators/lifts.
Special Advise
Patients Concern
Disease/Condition Glossary
Heart failure occurs when the heart's muscle does not properly pump blood to the body parts. Heart failure symptoms include shortness of breath, swollen legs, fatigue (lack of energy or feeling of tiredness), and increased heartbeat. In this condition, the heart becomes too weak and does not pump enough. It is a life-threatening condition and requires immediate hospitalization.
FAQs
Isosorbide Dinitrate+hydralazine is used to treat heart failure, a condition that occurs when the heart does not pump enough blood for the body's needs.
Isosorbide Dinitrate+hydralazine relaxes the heart's muscles and widens the heart's veins and arteries for easy flow of blood to every part of our body. It helps lower raised blood pressure by relaxing and widening the heart's muscles.
No, keep using the Isosorbide Dinitrate+hydralazine as advised by your doctor, even if you feel well. Stopping the Isosorbide Dinitrate+hydralazine suddenly may lead to serious complications of heart failure.
Yes, the use of Isosorbide Dinitrate+hydralazine can make you feel dizzy. This may often occur when you suddenly rise from a sitting or lying position. To lower the chance of feeling dizzy (faint) or passing out, rise slowly if you have been lying down or sitting.
Keep this medicine tightly closed in the container or the pack it came in. Store it according to the instructions mentioned on the pack or label. Dispose of unused medicine. Make sure pets, children, and other people do not consume it.
Isosorbide Dinitrate+hydralazine may cause headache in some individuals, as it is reported as a common side effect. However, this effect does not require medical attention and gradually resolves over time. If this side effect persists longer, please consult your doctor.
Take Isosorbide Dinitrate+hydralazine with or without food, accompanied by a glass of water. Swallow the tablet whole, without chewing, breaking, or crushing it. Follow your doctor's instructions for dose and duration, and complete the entire prescribed course.
The common side effects of the Isosorbide Dinitrate+hydralazine that may occur in some individuals are headache, nausea, dizziness, and light headedness (faint feeling). Most of these side effects of Isosorbide Dinitrate+hydralazine do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.
No, it is advisable not to drink alcohol while taking Isosorbide Dinitrate+hydralazine. Drinking alcohol during treatment may cause increased dizziness and drowsiness or it may cause unpleasant side effects.
Yes, there are some precautions or warnings associated with Isosorbide Dinitrate+hydralazine. Exercise caution while using this medication and it is not advisable for individuals with low blood pressure. Pregnant or breastfeeding women should consult their doctor before use. Additionally, it may cause dizziness, so driving after taking this medication is not recommended.
If you miss a dose of Isosorbide Dinitrate+hydralazine, take it as soon as you remember. However, if it's close to your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Never take a double dose to make up for a missed one.
