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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Isorus Tablet is used to treat heart failure. It contains Isosorbide dinitrate and Hydralazine, which relaxes the heart's muscles and widens the heart's veins and arteries for easy flow of blood to every part of the body. Thus, it helps lower raised blood pressure and treat heart failure. It may cause side effects like headache, nausea, dizziness, and lightheadedness (feeling faint). Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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in last 30 days

Manufacturer/Marketer :

Ajanta Pharma Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Isorus Tablet

Isorus Tablet belongs to a group of medicines called vasodilators used to treat heart failure. Heart failure occurs when the heart muscle does not pump blood normally, including shortness of breath, swollen legs, fatigue and increased heartbeat. In this condition, the heart becomes too weak and cannot pump enough blood and oxygen to the organs and tissues of the body. 

Isorus Tablet contains Isosorbide dinitrate and Hydralazine. Isosorbide dinitrate relaxes the heart's muscles and widens the heart's veins and arteries for easy flow of blood to every part of the body. Hydralazine helps lower raised blood pressure by relaxing and widening the heart's muscles. Together, Isorus Tablet helps treat heart failure.

Take Isorus Tablet as your doctor has prescribed it. In some cases, Isorus Tablet can cause side effects like headache, nausea, dizziness, and lightheadedness (feeling faint). Most of these side effects of Isorus Tablet do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

If you are known to be allergic to Isorus Tablet or any other medicines, please inform your doctor. Before taking Isorus Tablet , let your doctor know if you have had a heart attack within the last 30 days, low blood pressure, stroke (inadequate blood supply in the brain that causes damage to the brain), or high pressure within the brain. Please do not stop taking Isorus Tablet on your own, as it may lead to the recurrence of symptoms or worsen the condition.

Uses of Isorus Tablet

Treatment of Heart failure.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Isorus Tablet belongs to a group of vasodilators used to treat heart failure. Isorus Tablet contains Isosorbide dinitrate and Hydralazine. Isosorbide dinitrate belongs to a group of drugs known as nitrates. Isosorbide dinitrate relaxes the heart's muscles and stretches or enlarges the heart's veins and arteries. Hydralazine belongs to a group of drugs known as vasodilators, which help lower raised blood pressure by relaxing and widening the heart's blood vessels.

How Isorus Tablet Works

Isorus Tablet contains Isosorbide dinitrate and Hydralazine. Isosorbide dinitrate relaxes the heart's muscles and widens the heart's veins and arteries for easy flow of blood to every part of the body. Hydralazine helps lower raised blood pressure by relaxing and widening the heart's muscles. Together, Isorus Tablet helps treat heart failure.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Isorus Tablet

  • Headache
  • Nausea
  • Dizziness
  • Lightheadedness (feeling faint)

What if I have taken an overdose of Isorus Tablet

Do not take more than the prescribed dose of Isorus Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Isorus Tablet if you have low blood pressure because even a low dose of Isorus Tablet may produce low blood pressure. If you are pregnant or planning any pregnancy, let your doctor know about this before taking Isorus Tablet as it crosses the placenta and can affect the unborn baby (fetus). Do not drive by using this Isorus Tablet because it produces dizziness that may cause an accident. You may experience tingling or numbness, so your doctor may prescribe a vitamin B6 supplement (pyridoxine). Hydralazine passes into breast milk, so its use in lactating mothers should be avoided. 

Drug-Drug Interactions

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Isosorbide dinitrateTadalafil
Critical
Isosorbide dinitrateAvanafil
Critical

Drug-Drug Interactions

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Isosorbide dinitrateTadalafil
Critical
How does the drug interact with Isorus Tablet 15's:
Taking Tadalafil with Isorus Tablet 15's can increase the risk or severity of low blood pressure.

How to manage the interaction:
Taking Isorus Tablet 15's with Tadalafil is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, or heart palpitations. Do not discontinue any medications without consulting a doctor.
Isosorbide dinitrateAvanafil
Critical
How does the drug interact with Isorus Tablet 15's:
Taking Avanafil with Isorus Tablet 15's can cause low blood pressure.

How to manage the interaction:
Taking Isorus Tablet 15's with Avanafil is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, priapism in males (persistent and painful erection unrelated to sexual activity). Do not discontinue any medications without consulting a doctor.
Isosorbide dinitrateSildenafil
Critical
How does the drug interact with Isorus Tablet 15's:
Coadministration of Isorus Tablet 15's and Sildenafil can increase the risk of low blood pressure.

How to manage the interaction:
Taking Isorus Tablet 15's and Sildenafil together is generally avoided as it can lead to an interaction, it can be taken only if advised by your doctor. However, if you experience dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, and priapism (prolonged and painful erection unrelated to sexual activity) contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
Isosorbide dinitrateRiociguat
Critical
How does the drug interact with Isorus Tablet 15's:
Taking Riociguat with Isorus Tablet 15's may lead to excessively low blood pressure.

How to manage the interaction:
Taking Isorus Tablet 15's with Riociguat is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, priapism in males (persistent and painful erection unrelated to sexual activity). Do not discontinue any medications without consulting a doctor.
Isosorbide dinitrateLidocaine
Severe
How does the drug interact with Isorus Tablet 15's:
Taking Isorus Tablet 15's with lidocaine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking Isorus Tablet 15's and lidocaine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
Isosorbide dinitrateBupivacaine
Severe
How does the drug interact with Isorus Tablet 15's:
Combining Bupivacaine with Isorus Tablet 15's can increase the risk of methemoglobinemia(a rare condition that can lead to oxygen deprivation in tissues and vital organs due to reduced oxygen-carrying capacity of the blood).

How to manage the interaction:
Co-administration of Bupivacaine with Isorus Tablet 15's can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like grey discolouration of the skin, abnormal blood colouration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, confusion, consult a doctor right away. Do not stop using any medications without a doctor's advice.
Isosorbide dinitrateCabergoline
Severe
How does the drug interact with Isorus Tablet 15's:
Coadministration of Isorus Tablet 15's and cabergoline may decrease your blood pressure.

How to manage the interaction:
Co-administration of Isorus Tablet 15's with Cabergoline can result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these signs - headache, dizziness, feeling lightheaded, or fainting, contact your doctor immediately. Do not stop using any medications without talking to your doctor.
Isosorbide dinitrateChloroprocaine
Severe
How does the drug interact with Isorus Tablet 15's:
Taking Isorus Tablet 15's with chloroprocaine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking Isorus Tablet 15's and chloroprocaine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitations, anxiety, or confusion. Do not stop using any medications without consulting doctor.
Isosorbide dinitrateRopivacaine
Severe
How does the drug interact with Isorus Tablet 15's:
Taking Isorus Tablet 15's with ropivacaine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking Isorus Tablet 15's and ropivacaine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
Isosorbide dinitrateLevobupivacaine
Severe
How does the drug interact with Isorus Tablet 15's:
Taking Isorus Tablet 15's with levobupivacaine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking Isorus Tablet 15's and levobupivacaine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Follow a cholesterol-lowering diet.
  • Consume low salt and a low-fat diet.
  • Exercise regularly. It helps in maintaining proper weight and lowers cholesterol.
  • Limit salt and sugar intake.
  • Avoid smoking and alcohol consumption.
  • Choose healthy fats and cut down on trans fat.
  • Include omega-3 fatty acids, fibre-rich food, fruits, and vegetables.
  • Get active by doing physical activities such as swimming, brisk walking, or jogging. Take the stairs instead of elevators/lifts.

Habit Forming

No

Therapeutic Class

VASODILATORS
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Alcohol

Caution

Consuming alcohol with the Isorus Tablet is not advisable as it may cause unpleasant side effects, or you may become more sensitive to the effects of alcohol.

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Pregnancy

Caution

Isorus Tablet is not recommended during pregnancy. Please discuss with the doctor if you have any concerns.

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Breast Feeding

Caution

Isorus Tablet is not recommended during nursing. Please discuss with the doctor if you have any concerns.

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Driving

Caution

Isorus Tablet may cause dizziness in some people, so it may affect your ability to drive.

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Liver

Caution

Isorus Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Isorus Tablet to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Caution

The safety and effectiveness of Isorus Tablet in children have not been established.

FAQs

Isorus Tablet is used to treat heart failure, a condition that occurs when the heart does not pump enough blood for the body's needs.
Isorus Tablet relaxes the heart's muscles and widens the heart's veins and arteries for easy flow of blood to every part of our body. It helps lower raised blood pressure by relaxing and widening the heart's muscles.
No, keep using the Isorus Tablet as advised by your doctor, even if you feel well. Stopping the Isorus Tablet suddenly may lead to serious complications of heart failure.
Yes, the use of Isorus Tablet can make you feel dizzy. This may often occur when you suddenly rise from a sitting or lying position. To lower the chance of feeling dizzy (faint) or passing out, rise slowly if you have been lying down or sitting.
Keep this medicine tightly closed in the container or the pack it came in. Store it according to the instructions mentioned on the pack or label. Dispose of unused medicine. Make sure pets, children, and other people do not consume it.
Isorus Tablet may cause headache in some individuals, as it is reported as a common side effect. However, this effect does not require medical attention and gradually resolves over time. If this side effect persists longer, please consult your doctor.
Take Isorus Tablet with or without food, accompanied by a glass of water. Swallow the tablet whole, without chewing, breaking, or crushing it. Follow your doctor's instructions for dose and duration, and complete the entire prescribed course.
The common side effects of the Isorus Tablet that may occur in some individuals are headache, nausea, dizziness, and light headedness (faint feeling). Most of these side effects of Isorus Tablet do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.
No, it is advisable not to drink alcohol while taking Isorus Tablet . Drinking alcohol during treatment may cause increased dizziness and drowsiness or it may cause unpleasant side effects.
Yes, there are some precautions or warnings associated with Isorus Tablet . Exercise caution while using this medication and it is not advisable for individuals with low blood pressure. Pregnant or breastfeeding women should consult their doctor before use. Additionally, it may cause dizziness, so driving after taking this medication is not recommended.
If you miss a dose of Isorus Tablet , take it as soon as you remember. However, if it's close to your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Never take a double dose to make up for a missed one.

Country of origin

India

Manufacturer/Marketer address

Ajanta House, Charkop, Kandivli West, Mumbai 400 067, India
Other Info - ISO0249

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