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Indapamide

About Indapamide

Indapamide is used for the treatment of hypertension (high blood pressure). Additionally, Indapamide is used to reduce the risk of heart failure and oedema (a buildup of fluid in the body). Hypertension is a medical condition in which the blood exerts high pressure against the walls of blood vessels. This condition can put a person on severe health complications, including stroke, heart failure, heart attack, and aneurysm.

Indapamide contains Indapamide, which works by inhibiting the reabsorption of sodium in the body, resulting in an increase in chloride, sodium, and water excretion through urine.

Sometimes, you may experience dehydration, dizziness, headache, fatigue, nausea, itching, and abdominal pain. Most of these side effects of Indapamide do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

You can take Indapamide with food or without food. It should be swallowed whole with a glass of water. Do not chew, bite, or break it. Your doctor will advise you on how often you take your tablets based on your medical condition.

Please inform your doctor if you have had an allergic reaction to Indapamide, are pregnant, are breastfeeding, have gout, liver disease, kidney problems, heart failure, diabetes, a heart valve problem, or a heart attack. Indapamide should not be stopped even if you feel better without consulting your doctor.

Uses of Indapamide

Indapamide is used in the treatment of high blood pressure and fluid retention. The detailed uses of Indapamide are as follows: • Lowers high blood pressure: Indapamide helps to reduce blood pressure by relaxing blood vessels and removing excess salt and water from the body. • Reduces swelling (edema): Indapamide helps to reduce swelling in the legs, ankles, or other parts of the body by increasing urine output. • Protects heart and kidneys: Indapamide lowers the risk of heart attacks, strokes, and kidney problems caused by long-term high blood pressure.

Medicinal Benefits

  • Indapamide is prescribed for the treatment of high blood pressure.
  • Being a diuretic medication, Indapamide enhances the excretion of sodium and water through urine by restricting sodium absorption in the nephron tubes.
  • If high blood pressure is not controlled for a long time, then the arteries and the heart will not be able to function properly.
  • This may further increase the chances of damage to the brain's blood vessels, resulting in a heart attack and serious kidney failure.
  • Taking Indapamide at the right time can help control blood pressure and ensure the heart functions properly.

Directions for Use

  • Indapamide can be taken with or without food as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Indapamide as a whole with a glass of water.
  • Do not crush, break, or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Indapamide

  • Dizziness
  • Blurred vision
  • Fatigue
  • Nausea
  • Abdominal pain
  • Dry mouth
  • Headache
  • Constipation
  • Diarrhoea
  • Itching
  • Rashes
  • Shortness of breath

Drug Warnings

  • Indapamide can increase the chances of light-headedness, so rise slowly if you are sitting and avoid operating any machine or doing any work that needs mental alertness.
  • Before taking Indapamide, tell the doctor if you have any allergies to the active and inactive ingredients present in it.
  • Also, let your doctor know if you have a history of anuria (kidneys aren't producing urine)/ renal dysfunction, fluid or electrolyte imbalance, liver disease, lupus erythematosus (an autoimmune inflammatory disease-causing scaly red patches on the skin), and asthma.
  • Indapamide may lower down the potassium level in the body, so ask the doctor about how to add it to the diet.
  • Indapamide should only be given during pregnancy when the doctor strongly suggests it.
  • Indapamide could pass in the breast milk, so ask your doctor if you are a breastfeeding woman before taking it.
  • Indapamide should not be given to children as safety has not been established.

Drug Interactions

Drug-Drug Interactions: Indapamide may interact with other diuretic medications (furosemide, torsemide), antihypertensive drugs (ramipril, amlodipine, baclofen, levodopa, clonidine), a medicine used to treat bipolar disorder (lithium, risperidone, amisulpride), painkillers (ibuprofen, naproxen), and blood thinners (warfarin).

Drug-Food Interactions: Indapamide can be taken with or without a meal. However, it should be taken early in the day and at the same time of day. It is best to avoid heavy meals with Indapamide, as it will help the medicine work more effectively. However, one should tell their doctor if they are using multi-minerals or any ayurvedic supplements. It is best to limit the intake of salt.

Drug-Disease Interactions: Indapamide can interact with certain diseases. Hence, it is advisable to tell the doctor about the past or current medical history, including anuria (kidneys are not producing urine)/ renal dysfunction, fluid or electrolyte imbalance, liver disease, lumps erythematosus (an autoimmune inflammatory disease-causing scaly red patches on the skin), and asthma.

Drug-Drug Interactions Checker List:

  • FUROSEMIDE
  • TORSEMIDE
  • AMLODIPINE
  • RAMIPRIL
  • BACLOFEN
  • LEVODOPA
  • CLONIDINE
  • AMBROXOL
  • LITHIUM
  • RISPERIDONE
  • IBUPROFEN
  • NAPROXEN
  • WARFARIN
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      It is best to avoid or limit alcohol intake. Alcohol may aggravate the side effects and may cause a sudden drop in blood pressure and dizziness.

    • Safety Warning

      Pregnancy

      consult your doctor

      The use of Indapamide is not allowed during pregnancy unless prescribed by the doctor.

    • Safety Warning

      Breast Feeding

      consult your doctor

      Indapamide tends to pass in the breast milk, so talk to your doctor before taking this medicine. A high dose of Indapamide may reduce milk production, so never take it without consulting a doctor.

    • Safety Warning

      Driving

      unsafe

      Indapamide could make a person feel dizzy or drowsy. Therefore it is advised to avoid driving or doing any task that needs a clear vision.

    • Safety Warning

      Liver

      caution

      Indapamide should be taken with caution as this is a diuretic medicine, so if a person is already dealing with liver disease, then Indapamide may cause serious loss of potassium from the body, resulting in vomiting or diarrhoea.

    • Safety Warning

      Kidney

      caution

      Indapamide could cause a high level of nitrogen in the body. If a person is having trouble urinating, then the doctor will not allow the usage of Indapamide. However, the use of Indapamide is contraindicated in patients whose kidneys cannot produce urine.

    • Safety Warning

      Children

      unsafe

      Indapamide is not approved in children younger than 18 years of age.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Consume antioxidant-rich food. Blueberries, cherries, tomatoes, squash, and bell peppers are high in antioxidants.
    • Eat natural diuretic foods. Asparagus, beets, green beans, grapes, onion, leafy greens, pineapple, leeks, pumpkin, and garlic are all-natural diuretic foods.
    • Use healthy cooking oils like soybean, olive, canola, and coconut oil.
    • You should avoid refined foods such as white bread, spaghetti, sugar, and red meat.
    • Reduce or eliminate Trans fatty acids, which are found in commercially baked items such as cookies, cakes, crackers, French fries, onion rings, doughnuts, and processed foods.
    • Avoid consumption of too much salt or salty food.
    • Keep your weight under control with a BMI of 19.5-24.9.
    • Regular physical activity or exercise, like walking, improves your blood flow.
    • When possible, elevate your legs or the swollen area on a chair or pillows.
    • Avoid standing or sitting for extended periods of time.
    • Avoid chronic stress, as it can raise your blood pressure.
    • Spend time with your loved ones to cope with stress and practice mindfulness techniques.
    • Quitting smoking and alcohol consumption is the best strategy to lower the risk of many health complications.

    Patients Concern

    Disease/Condition Glossary

    Hypertension: The blood exerts increased pressure on the walls of blood vessels, leading to hypertension. High blood pressure is expressed as systolic/diastolic pressure. Systolic pressure is the pressure in the arteries when the heart beats or pumps out blood. Diastolic pressure is the pressure in the arteries between the heartbeats. Blood pressure is measured in millimetres of mercury (mmHg) by a blood pressure monitor called a sphygmomanometer. Some of the symptoms are headache, dizziness, nosebleeds, altered vision, chest pain, weakness, and shortness of breath. However, most of the time, the signs and symptoms of hypertension are none.

    Oedema: Oedema, also known as fluid overload, occurs due to fluid build-up in spaces between the cells. Oedema can result from a variety of factors. Some oedema reasons are caused by your lifestyle, while an underlying medical problem causes others. Shortness of breath, chest pain (angina), abnormal heart rhythms (arrhythmia), and swelling in hands or abdominal areas are the symptoms of oedema.

    FAQs

    Indapamide is used for the treatment of hypertension (high blood pressure). Additionally, it is used to reduce the risk of heart failure and oedema (a build-up of fluid in the body).

    Indapamide belongs to the group of medicines called diuretics that increase the amount of urine that is passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Thus, it helps to lower high blood pressure, reducing the chances of heart attack or stroke.

    Unless suggested by the doctor, to take Indapamide in morning or night, one should fix a time slot, and they should take it regularly at the same time. However, one should avoid taking it at night time or just before bed as this medicine causes frequent urination. So, best to take it before 4 hours going to bed.

    As hypertension is a serious medical issue, so taking Indapamide help to reduce the risk of heart disease and other serious conditions. So, one should not stop taking medicine without consulting with their doctor. However, depending upon the condition, the doctor will adjust the dosing.

    Even if a person achieved their goal of bringing their blood pressure back to normal, they should not stop taking it without asking a doctor. Only after the doctor's recommendation, the dosage of Indapamide could be adjusted.

    Available Medicines for

    Indapamide

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