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Telmisartan+hydrochlorothiazide

About Telmisartan+hydrochlorothiazide

Hydrochlorothiazide+telmisartan belongs to the class of anti-hypertensives primarily taken for the treatment of hypertension (high blood pressure). Hypertension or high blood pressure is a life-long or chronic condition in which the force exerted by the blood against the artery wall becomes too high. It can lead to the risk of heart diseases, like heart attack and stroke.

Hydrochlorothiazide+telmisartan is a combination of Telmisartan (angiotensin II receptor antagonist) and Hydrochlorothiazide (thiazide diuretic or water pill). Telmisartan is an angiotensin receptor blocker that helps to relax and widen the blood vessels (arteries). Hydrochlorothiazide is a diuretic that prevents absorption of excess salt in the body, preventing fluid retention. Together it lowers blood pressure and prevents the risk of stroke, heart attack and oedema (fluid retention).

You can take Hydrochlorothiazide+telmisartan with food or empty stomach. It should be swallowed whole with a glass of water. Your doctor will advise you how often you take your tablets based on your medical condition. In some cases, you may experience dizziness, feeling tired, nausea, diarrhoea, back pain, and cold/flu symptoms. Most of these side effects of Hydrochlorothiazide+telmisartan do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not use potassium supplements or its salt substitutes, unless the doctor has told you. In rare cases, Hydrochlorothiazide+telmisartan can cause a condition that results in the skeletal muscle problem, leading to further to kidney failure. If you notice unexplained muscle pain, dark colour urine, tenderness, or weakness, especially if you also have a fever or unexplained tiredness, immediately contact the doctor. Do not use if you are pregnant, planning to get pregnant, stop taking Hydrochlorothiazide+telmisartan and tell your doctor right away. Besides this, you should not use Hydrochlorothiazide+telmisartan if you are unable to urinate. If you have diabetes, do not use Hydrochlorothiazide+telmisartan with any medication that contains aliskiren (a blood pressure medicine). Before taking Hydrochlorothiazide+telmisartan, tell your doctor if you have ever had liver disease, kidney failure, glaucoma, high or low levels of magnesium or potassium in your blood, have allergies or asthma, lupus (an autoimmune disease), diabetes, or an allergy to penicillin or sulfa drugs.  

Uses of Telmisartan+hydrochlorothiazide

Treatment of Hypertension (high blood pressure)

Medicinal Benefits

Hydrochlorothiazide+telmisartan works by relaxing and widening the blood vessels (arteries) making the heart more efficient at pumping blood throughout the body. It helps to lower high blood pressure thus reduces the chances of future heart attack and stroke. Besides this, it prevents excessive water and electrolytes (like sodium, potassium etc.) from the body through urine that can raise high blood pressure.

Directions for Use

Hydrochlorothiazide+telmisartan should not be used unless prescribed by a doctor. Always take Hydrochlorothiazide+telmisartan exactly as your doctor told you. Your doctor will advise you how often you take your tablets based on your medical condition. Swallow Hydrochlorothiazide+telmisartan with a full glass of water. If required tablets can be broken in half to give a smaller dose.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Telmisartan+hydrochlorothiazide

  • Dizziness

  • Feeling tired

  • Nausea

  • Diarrhoea

  • Back pain

  • Cold/flu symptoms

Drug Warnings

Hydrochlorothiazide+telmisartan should not be given to the people allergic to Hydrochlorothiazide+telmisartan, have low blood pressure (less than 90 mm of Hg), have had a heart attack, kidney disease, liver disease, pregnant women, or planning to get pregnant and breastfeeding women. It should be used with caution in patients suffering from diabetes. Besides this, it is contraindicated in low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart), and aortic stenosis (heart valve problem). Hydrochlorothiazide+telmisartan can pass into breast milk, but its effect on the baby is not known. So, it is better to tell your doctor if you are taking Hydrochlorothiazide+telmisartan and breastfeeding.

Drug Interactions

Drug-Drug interaction: This medicine may have an interaction with medicines used to treat mood disorders (lithium), medicines used to treat heart disorders (digoxin), antidiabetic medicines (metformin, insulin), medicines used to treat erectile dysfunction (sildenafil), medicines used to lower cholesterol levels (such as simvastatin), immunosuppressants (cyclosporine), and other anti-hypertensive medicines (aliskiren, enalapril, lisinopril, ramipril),

Drug-Food Interaction: Hydrochlorothiazide+telmisartan may interact with high potassium-containing food and drinks. So, if you are using any of the OTC items, please tell your doctor.

Drug-Disease Interaction: The efficacy of Hydrochlorothiazide+telmisartan is affected, and the disease condition may even worsen if taken in patients with a recent or history of heart attack, low blood pressure, low potassium level, low electrolytes (sodium, potassium, calcium etc.), anuria (non-passage of urine), angioedema (an allergic condition with swelling under the skin), lupus (an autoimmune disease), kidney disease, liver disease, and diabetes.

Drug-Drug Interactions Checker List:

  • LITHIUM
  • DIGOXIN
  • METFORMIN
  • INSULIN HUMAN
  • SILDENAFIL
  • SIMVASTATIN
  • ENALAPRIL
  • LISINOPRIL
  • RAMIPRIL
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      You are recommended not to consume alcohol along with Hydrochlorothiazide+telmisartan to avoid unpleasant side effects like drowsiness, dizziness and liver damage.

    • Safety Warning

      Pregnancy

      unsafe

      Hydrochlorothiazide+telmisartan is not recommended during pregnancy. This medicine may cause fetal damage and can affect the unborn baby (foetus).

    • Safety Warning

      Breast Feeding

      caution

      Hydrochlorothiazide+telmisartan is known to pass breast milk, but, its effect on the baby is not known. So, before breastfeeding, let your doctor know about this.

    • Safety Warning

      Driving

      unsafe

      Drive with caution, Hydrochlorothiazide+telmisartan usually causes drowsiness and affects driving ability.

    • Safety Warning

      Liver

      caution

      Hydrochlorothiazide+telmisartan to be taken with caution, especially if you have or have had a history of liver disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

    • Safety Warning

      Kidney

      unsafe

      Not recommended in patients with chronic kidney disease (severe renal impairment). Safety and effectiveness in patients with severe renal impairment have not been established.

    • Safety Warning

      Children

      safe if prescribed

      Hydrochlorothiazide+telmisartan can be given safely to children aged 6 - 12 years provided; dose has been prescribed by a child specialist.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Keep your weight under control with BMI 19.5-24.9.

    • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help you to lower your raised blood pressure by about 5 mm of Hg.

    • Limit intake of sodium chloride (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.

    • If you are taking alcohol then only one serving for women and two servings for men is advisable.

    • Quitting smoking is the best strategy to lower the risk of heart disease.

    • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress and practice mindfulness techniques.

    • Monitor your blood pressure daily and if there is too much fluctuation then immediately contact your doctor.

    • Try to include heart-healthy omega 3 fatty acids containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil can help in lowering your elevated blood pressure.

    Patients Concern

    Disease/Condition Glossary

    Hypertension: It is a chronic condition when blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Blood pressure is the measurement of the force that our heart uses to pump blood to all parts of the body. Raised blood pressure can cause chest pain (angina) and heart attack (when blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor or sphygmomanometer. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is the pressure when your heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg and, diastolic pressure is 90 mm of Hg. Ideal blood pressure should be between 90/60 mm of Hg and 120/80 mm of Hg.

    FAQs

    Hydrochlorothiazide+telmisartan is used for the treatment of hypertension (high blood pressure).

    No, you are advised to inform your doctor and monitor your blood pressure for at least two weeks before stopping the medicine. Depending upon your current blood pressure readings, there is a possibility your doctor may lower your medicine dosage and not recommend to discontinue it.

    Yes, Hydrochlorothiazide+telmisartan can cause ankle swelling in some cases which can be due to oedema (fluid retention). If you feel the swelling is persistent, please inform your doctor.

    Hydrochlorothiazide+telmisartan can be safely taken as long as your doctor has prescribed it to you. Conditions such as high blood pressure are life-long conditions, and one should not abruptly discontinue it without discussing it with a doctor.

    Yes, Hydrochlorothiazide+telmisartan can cause dizziness. It is advised to avoid driving or operate any heavy machinery while taking Hydrochlorothiazide+telmisartan. In case you feel dizzy or lightheaded, it is advised to rest for some time until you feel better.

    You should not take Hydrochlorothiazide+telmisartan if you have ever had liver disease, kidney failure, glaucoma, high or low levels of magnesium or potassium in your blood, have allergies or asthma, lupus (an autoimmune disease), diabetes, or allergic to penicillin or sulfa drugs, anuria (reduction or absence of urine) and pregnant women in their second or third trimesters. Besides this avoid using Hydrochlorothiazide+telmisartan (in case of diabetes) with aliskiren (a blood pressure medicine) as it can lead to a life-threatening condition.

    In case, you have missed a dose of Hydrochlorothiazide+telmisartan, you are advised to take it as soon as you remember. However, try not to miss a dose in the first place, if it's time for you to take your next dose, then do not take both the doses together. Take only one dose, taking a double dose of Hydrochlorothiazide+telmisartan will lead to low blood pressure.

    No, it is not recommended to take Hydrochlorothiazide+telmisartan if you are pregnant as it can cause damage to the unborn baby (may lead to fetal toxicity).

    Yes, prolonged intake of Hydrochlorothiazide+telmisartan can cause an increase in blood potassium level. So, patients taking Hydrochlorothiazide+telmisartan should avoid taking supplements and food rich in potassium to avoid any unpleasant side-effect.

    Avoid using high potassium-containing food and drinks, potassium supplements or salt substitutes, unless the doctor has told you. You are recommended not to consume alcohol along with Hydrochlorothiazide+telmisartan to avoid unpleasant side effects like drowsiness, dizziness and liver damage.

    Taking too much of Hydrochlorothiazide+telmisartan may cause an overdose. The symptoms of overdose include fainting, feeling light-headed and slow or fast heart rate. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

    Do not discontinue Hydrochlorothiazide+telmisartan without consulting your doctor. To treat your condition effectively, keep taking Hydrochlorothiazide+telmisartan for the prescribed duration.

    If you stop taking Hydrochlorothiazide+telmisartan, your blood pressure may rise again. This could raise your chances of a heart attack, stroke, kidney failure, or other complications. Therefore, do not discontinue Hydrochlorothiazide+telmisartan without consulting your doctor.

    Yes, it is safe to take Hydrochlorothiazide+telmisartan for a long time if prescribed by the doctor. Continue taking Hydrochlorothiazide+telmisartan for the prescribed duration.

    Since high blood pressure is a chronic condition, you may need to take Hydrochlorothiazide+telmisartan for a longer duration. However, the doctor will determine the duration of treatment based on your condition.

    You may not feel a difference even after taking Hydrochlorothiazide+telmisartan as high blood pressure does not have any symptoms. This does not mean you should stop taking Hydrochlorothiazide+telmisartan. Talk to the doctor if you have any concerns.

    Hydrochlorothiazide+telmisartan may cause erectile dysfunction in some people. Please consult the doctor if you experience any sexual problems while taking Hydrochlorothiazide+telmisartan.

    Follow a healthy diet and exercise regularly. Avoid smoking and alcohol consumption. Manage stress by doing meditation. Limit salt, fried foods, and processed foods.

    The active ingredients in Hydrochlorothiazide+telmisartan are Telmisartan (angiotensin II receptor antagonist) and Hydrochlorothiazide (thiazide diuretic or water pill).

    Hydrochlorothiazide+telmisartan can be taken on an empty stomach or with food.

    Hydrochlorothiazide+telmisartan may cause side effects like dizziness, feeling tired, nausea, diarrhoea, back pain, and cold/flu symptoms. Most of these side effects of Hydrochlorothiazide+telmisartan do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

    You are recommended not to consume alcohol along with Hydrochlorothiazide+telmisartan to avoid unpleasant side effects like drowsiness, dizziness and liver damage.

    Store Hydrochlorothiazide+telmisartan at room temperature, in a dry place. Keep out of sight and reach of children.

    Available Medicines for

    Telmisartan+hydrochlorothiazide

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