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Etoricoxib

About Etoricoxib

Etoricoxib is used to treat pain, swelling and inflammation in osteoarthritis, rheumatoid arthritis, ankylosing spondylitis and gout in people greater than 16 years of age. Besides this, it is also used to treat moderate pain after dental surgery.

Etoricoxib contains ‘etoricoxib’, which works by blocking the release of a chemical messenger called prostaglandin, produced by COX-2, which is responsible for pain, swelling and inflammation. 

Common side-effects of Etoricoxib are stomach pain, dry socket, swelling of the legs, dizziness, headache, palpitations, increased blood pressure, shortness of breath, constipation, flatulence, heartburn, diarrhoea, indigestion (dyspepsia), nausea, vomiting, general weakness and flu-like illness (fever, cold, cough, or sore throat).

Do not take Etoricoxib if you are allergic to etoricoxib, other pain killers or other ingredients. Inform your doctor if you have ulcers or bleeding in your stomach, severe liver and/or kidney impairment, colitis (inflammation of the large intestine), uncontrolled blood pressure, or heart problems such as chest pain, heart attack, heart failure and stroke.

Uses of Etoricoxib

Etoricoxib is used in the treatment of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, gout. The detailed uses of Etoricoxib are as follows:
• Treatment of Osteoarthritis: Etoricoxib helps reduce pain and stiffness in joints.
• Rheumatoid Arthritis: Etoricoxib eases joint inflammation caused by autoimmune disorders.
• Gouty Arthritis: Etoricoxib alleviates joint pain triggered by uric acid buildup.
• Management of Ankylosing Spondylitis: Etoricoxib manages inflammation in the spine and large joints.
• Post-Surgical Pain: Etoricoxib is useful for relieving pain after dental or other minor surgeries.

Medicinal Benefits

  • Etoricoxib contains etoricoxib, which is a non-steroidal anti-inflammatory drug (NSAID).
  • It acts as bothan  analgesic (reduces pain) and an anti-inflammatory (reduces inflammation) agent.
  • Etoricoxib is a selective COX-2 inhibitor. COX-2 enzymes are responsible for converting arachidonic acid to prostaglandins, which are inflammatory mediators.
  • The blocking of COX-2 reduces the production of prostaglandins, eventually decreasing pain and inflammation.

Directions for Use

  • Etoricoxib can be taken with or without food as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Etoricoxib as a whole with a glass of water.
  • Do not crush, break, or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Etoricoxib

  • Dizziness
  • Headache
  • Palpitations (pounding heart)
  • Increased blood pressure
  • Shortness of breath
  • Constipation
  • Flatulence
  • Heartburn
  • Diarrhoea
  • Indigestion (dyspepsia)
  • Nausea (feeling sick)
  • Vomiting (being sick)
  • Mouth ulcers
  • Weakness
  • Fatigue
  • Flu-like illness (fever, cold, cough, or sore throat)

Drug Warnings

  • If you are allergic to Etoricoxib or any other medicines, please tell your doctor.
  • Before taking Etoricoxib, inform your doctor if you have a history of stomach bleeding or ulcer, liver or kidney diseases, dehydration because of prolonged vomiting or diarrhoea and swelling due to fluid retention.
  • Inform your doctor if you have high blood pressure that is not treated or controlled, as Etoricoxib may increase blood pressure in some cases.
  • Do not take Etoricoxib if you are treated for infection, as Etoricoxib can mask fever (a sign of disease).
  • Do not take Etoricoxib if you smoke, have diabetes (high blood sugar), or high cholesterol, as Etoricoxib increases the risk of heart attack or stroke.
  • Avoid lying down for at least half an hour after using Etoricoxib. People who have had heart attacks and strokes should not take Etoricoxib.

Drug Interactions

Drug-Drug interactions: Etoricoxib may interact with anticoagulants (warfarin and aspirin), antibiotic (rifampicin), immunosuppressant (methotrexate), antihypertensives (enalapril, ramipril, losartan, valsartan, and minoxidil), diuretics, antiarrhythmic drug (digoxin), antiasthmatic drug (salbutamol) and oral contraceptives.

Drug-Food interactions: No interactions found.

Drug-Disease interactions: Etoricoxib should be used with caution in patients with stomach ulcers or bleeding, severe kidney disease, liver diseases, colitis (inflammation of the large intestine), uncontrolled blood pressure, heart failure, stroke, and other heart problems.

Drug-Drug Interactions Checker List:

  • WARFARIN
  • ASPIRIN
  • RIFAMPICIN
  • METHOTREXATE
  • ENALAPRIL
  • RAMIPRIL
  • LOSARTAN
  • VALSARTAN
  • MINOXIDIL
  • DIGOXIN
  • SALBUTAMOL
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      Alcohol intake may increase the risk of heart problems when using Etoricoxib.

    • Safety Warning

      Pregnancy

      unsafe

      Etoricoxib is a category C medicine. It shows toxic effects on the fetus when given to pregnant women. Consult your doctor for further advice.

    • Safety Warning

      Breast Feeding

      caution

      Etoricoxib should be used with caution in breastfeeding mothers and only when prescribed by a doctor.

    • Safety Warning

      Driving

      caution

      Etoricoxib may cause dizziness. So, you should not drive or operate heavy machinery after taking Etoricoxib.

    • Safety Warning

      Liver

      caution

      Etoricoxib may alter liver function. So, dose adjustments are necessary for patients with liver diseases.

    • Safety Warning

      Kidney

      caution

      Etoricoxib should be used with caution in patients with kidney diseases. Dosage adjustments are necessary for patients with severe renal impairment.

    • Safety Warning

      Children

      unsafe

      Etoricoxib is not recommended for children below 16 years of age.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Consume a healthy diet that includes fresh fruits and vegetables. Limit foods high in sugar content.
    • Do not take spicy, fried and processed foods.
    • Drink plenty of water to stay hydrated. 
    • Quit smoking.
    • Limit caffeine and alcohol intake.

    Special Advise

    • Your doctor may monitor liver and kidney function if Etoricoxib is prescribed for the long term. 

    • Inform your doctor before taking the Etoricoxib if you had a history of a heart attack, bypass surgery or peripheral arterial disease.

    Patients Concern

    Disease/Condition Glossary

    Osteoarthritis: Osteoarthritis is the common type of arthritis in which the cartilage that cushions the ends of the bones erodes due to wear and tear over time. Common symptoms are joint pain and stiffness.

    Rheumatoid arthritis (RA): Rheumatoid arthritis (RA) is an autoimmune disease in which the immune cells attack the joints and cause bone erosion leading to severe pain and swelling. It may lead to joint deformity if left untreated.

    Ankylosing spondylitis: Ankylosing spondylitis is a type of arthritis in which inflammation is seen in the spine and large joints. It leads to pain and stiffness in the back and affected joints.

    Gout: Gout is an inflammatory condition in which uric acid deposits and crystallizes in the joints. It is characterized by acute, severe and recurring attacks of pain, especially at night; redness and swelling in the affected joints.

    FAQs

    Etoricoxib is used to treat pain, swelling and inflammation in osteoarthritis, rheumatoid arthritis, ankylosing spondylitis and gout in people greater than 16 years of age. Besides this, it is also used to treat moderate pain after dental surgery.

    Etoricoxib contains ‘etoricoxib’, which is a non-steroidal anti-inflammatory drug (NSAID). It is a COX-2 inhibitor. COX-2 enzyme produces prostaglandins that cause pain, swelling and inflammation.

    You should not take Etoricoxib for the longer term, especially in higher doses, as it increases the risk of heart attack and stroke.

    Etoricoxib may cause dizziness. So, driving or operating heavy machinery is not advisable after taking Etoricoxib.

    Etoricoxib is not recommended for use in children below 16 years of age.

    Available Medicines for

    Etoricoxib

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