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Dimenhydrinate

About Dimenhydrinate

Dimenhydrinate is used to prevent and treat nausea (feeling sick), vomiting (being sick), and dizziness caused by motion sickness. Besides this, it is also used to treat nausea and vomiting associated with radiation sickness, surgery, and drug-induced Meniere disease (feelings of spinning and inner ear problems). Motion sickness is an illness caused by motion during travel, characterised by nausea and vomiting.

Dimenhydrinate contains Dimenhydrinate, which acts as both an antihistamine and an anticholinergic. It works by blocking histamine (H₁) receptors and muscarinic (M₁) receptors in the brain areas that control balance and nausea. This helps reduce the signals that cause motion sickness, leading to relief from nausea, vomiting, and dizziness.

Dimenhydrinate may cause side effects such as dry mouth, blurred vision, drowsiness, dizziness, headache, tiredness, disorientation, tinnitus, palpitations, and low blood pressure (hypotension). Most of these side effects do not require medical attention and resolve gradually over time. However, seek medical attention immediately if these side effects persist or worsen.

Notify your doctor if you have breathing problems (asthma, emphysema), high pressure in the eye (glaucoma), seizures (fits), liver, kidney, heart problems, chronic obstructive pulmonary disease (COPD), or sleep apnea (sleeping disorder). Consult your doctor if you are pregnant or breastfeeding. Dimenhydrinate should not be given to children below 2 years as the safety and effectiveness have not been established. Dimenhydrinate may cause dizziness, so drive or operate heavy machinery only if you are alert.

Uses of Dimenhydrinate

Dimenhydrinate is used in the treatment of motion sickness. The detailed uses of Dimenhydrinate are as follows:
• Motion Sickness Relief: Dimenhydrinate is effectively used to prevent and treat symptoms of motion sickness, including nausea, vomiting, and dizziness during travel by car, plane, or boat.
• Nausea and Vomiting: Dimenhydrinate can be used to alleviate nausea and vomiting that may occur due to other conditions, such as migraine headaches or certain gastrointestinal disorders.
• Postoperative Nausea: Dimenhydrinate is often administered to reduce nausea and vomiting after surgical procedures due to anesthesia.
• Vertigo Management: Dimenhydrinate can help manage vertigo symptoms, which are often associated with inner ear disorders.

Medicinal Benefits

Dimenhydrinate contains Dimenhydrinate, which helps prevent and treat nausea, vomiting, and dizziness caused by motion sickness, vertigo, radiation sickness, surgery, and drug-induced Meniere’s disease by calming the brain areas that control balance and nausea.

Directions for Use

  • Dimenhydrinate can be taken with or without food.
  • Take the first dose 30 to 60 minutes before travelling or starting any motion-related activity if using it for motion sickness.
  • It is typically administered every 4-6 hours as needed, or as directed by your doctor.
  • Swallow Dimenhydrinate as a whole with a glass of water.
  • Do not crush, chew, or break the medication.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Dimenhydrinate

  • Dry mouth
  • Blurred vision
  • Drowsiness
  • Dizziness
  • Headache
  • Tiredness

Drug Warnings

Do not take Dimenhydrinate if you are allergic to any of its contents. Before taking Dimenhydrinate, please tell your doctor if you are using any antidepressants. Dimenhydrinate is not intended for prolonged use unless prescribed by a physician. Inform your doctor if you are pregnant or breastfeeding. Antihistamine overdosage may cause hallucinations, convulsions, or death, especially in infants and children; it also produces excitation in younger children. So, dose adjustments may be necessary if prescribed to children. Dimenhydrinate should not be given to children below 2 years of age and patients who are unconscious or have severe drowsiness, dizziness, or headache. Inform your doctor if you have difficulty breathing, asthma or bronchitis (lung problems), epilepsy (fits), severe heart problems, liver or kidney problems, a stomach blockage, hearing problems, or increased pressure in the eye (glaucoma).

Drug Interactions

Drug-drug interactions: Dimenhydrinate may interact with other antihistamines (loratadine, diphenhydramine, cetirizine), pain relievers (codeine, morphine, hydrocodone), antidepressants (amitriptyline, imipramine), sedatives (diazepam and zolpidem), and antibiotics (gentamicin).

Drug-food interactions: Avoid consuming alcohol when taking Dimenhydrinate, as it may cause excessive sleepiness or drowsiness.

Drug-disease interactions: Dimenhydrinate should be used with caution in patients with respiratory diseases (such as asthma), liver or kidney problems, severe heart conditions, sleep disorders, seizures, and hearing problems.

Drug-Drug Interactions Checker List:

  • LORATADINE
  • DIPHENHYDRAMINE
  • CETIRIZINE
  • CODEINE
  • MORPHINE
  • HYDROCODONE
  • AMITRIPTYLINE
  • IMIPRAMINE
  • DIAZEPAM
  • ZOLPIDEM
  • GENTAMICIN
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      Avoid alcohol consumption while taking Dimenhydrinate, as it may cause increased drowsiness.

    • Safety Warning

      Pregnancy

      caution

      Dimenhydrinate is a pregnancy category B drug. Please consult your doctor before taking Dimenhydrinate if you are pregnant or planning to become pregnant. Your doctor will weigh the benefits and any potential risks before prescribing Dimenhydrinate.

    • Safety Warning

      Breast Feeding

      caution

      It is not known whether Dimenhydrinate passes into breast milk or harms a nursing baby. Please consult your doctor before taking Dimenhydrinate if you are breastfeeding.

    • Safety Warning

      Driving

      caution

      Dimenhydrinate may cause drowsiness and dizziness. So, avoid driving or operating heavy machinery while using Dimenhydrinate.

    • Safety Warning

      Liver

      caution

      Dimenhydrinate should be used with caution in patients with liver diseases. Please consult your doctor before taking Dimenhydrinate. Your doctor will weigh the benefits and any potential risks before prescribing Dimenhydrinate.

    • Safety Warning

      Kidney

      caution

      Dimenhydrinate should be used with caution in patients with kidney diseases. Please consult your doctor before taking Dimenhydrinate. Your doctor will weigh the benefits and any potential risks before prescribing Dimenhydrinate.

    • Safety Warning

      Children

      caution

      Dimenhydrinate is not recommended for use in children below 2 years of age. For children above 2 years of age, dose adjustments may be necessary if prescribed.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • ​​​​​​Avoid spicy, greasy, and acidic foods before travelling; it may increase the feeling of sickness.
    • Opt for cereals, apples, bananas, or bread.
    • Breathe the fresh air, if possible, by opening the window.
    • In many cases, a full stomach and excessive heat may worsen the symptoms of motion sickness, so space out your meals and eat light.
    • Position yourself where motion is least, like in the front seat of a car, the centre of a boat or ship.
    • Avoid alcohol 24 hours before travel and during travel.

    Patients Concern

    Disease/Condition Glossary

    Motion sickness: It is an illness caused by motion during travel. It usually occurs when you are travelling by car, boat, plane, or train. Your body's sensory organs send mixed messages to your brain, causing dizziness, lightheadedness, or nausea and vomiting. The illness usually goes away when the motion stops. Symptoms include nausea, vomiting, dizziness, and tiredness.

    FAQs

    Dimenhydrinate is used to prevent and treat nausea (feeling sick), vomiting (being sick), and dizziness caused by motion sickness. Besides this, it is also used to treat nausea and vomiting associated with radiation sickness, surgery, and drug-induced Meniere disease (feelings of spinning and inner ear problems).

    Dimenhydrinate contains Dimenhydrinate, which acts as both an antihistamine and an anticholinergic. It works by blocking histamine (H₁) receptors and muscarinic (M₁) receptors in the brain areas responsible for balance and nausea. This action helps reduce signals that lead to motion sickness, providing relief from nausea, vomiting, and dizziness.

    Yes, the use of Dimenhydrinate can cause dry mouth. If you feel excessively thirsty, increase your fluid intake and avoid consuming spicy and salty foods.

    Dimenhydrinate is an anti-sickness medication that takes approximately 30-60 minutes to take effect.

    Dimenhydrinate is usually recommended for short-term use. Do not take longer than prescribed unless advised by your doctor.

    Available Medicines for

    Dimenhydrinate

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