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Diclofenac+serratiopeptidase

About Diclofenac+serratiopeptidase

Diclofenac+serratiopeptidase belongs to the class of drugs known as 'non-steroidal anti-inflammatory drug' (NSAID). It is a fixed-dose combination composed of diclofenac and serratiopeptidase. Pain can be temporary (acute) or lifelong (chronic) in nature. Acute pain is for short time caused by damage to the tissues of the muscle, bone, or organs. While, chronic pain lasts for life long caused due to nerve damage, osteoarthritis, and dental pain due to damage of the tooth nerve, infection, decay, extraction, or injury.

Diclofenac+serratiopeptidase is used in the reduction of pain and inflammation due to bone or soft tissue injury, resolution of postoperative inflammation, oedema (swollen tissue with fluid) and pain. Diclofenac works by blocking the action of a chemical messenger known as cyclo-oxygenase (COX) which causes pain and swelling at the injured or damaged tissue. Serratiopeptidase is a proteolytic enzyme which helps in the breakdown of insoluble protein (fibrin) a by-product of blood clots into smaller units. It also causes thinning of the fluids in the body as a result of injury, thereby making fluid drainage smoother in the swollen tissue.

You can take Diclofenac+serratiopeptidase with food or without food. It should be swallowed whole with a glass of water. Do not chew, bite, or break it. Your doctor will advise you on how often you take Diclofenac+serratiopeptidase based on your medical condition. Diclofenac+serratiopeptidase may have common side effects like stomach ache, diarrhoea, nausea (feeling sick), and indigestion. Most of these side effects of Diclofenac+serratiopeptidase do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine of your own. Do not take Diclofenac+serratiopeptidase if you are allergic to painkillers like aspirin, ibuprofen, naproxen, or diclofenac. It is not recommended for use in children. Diclofenac+serratiopeptidase may be associated with a small increased risk of heart attack ‘myocardial infarction. It is advisable not to exceed the recommended dose or duration of treatment.

Uses of Diclofenac+serratiopeptidase

Treatment of Post-traumatic pain, Low back pain, Cervical pain, Spondylitis, Osteoarthritis, Rheumatoid arthritis.

Medicinal Benefits

Diclofenac+serratiopeptidase plays a vital role in reducing pain and inflammation by blocking the release of chemical messengers which cause pain and fever. Diclofenac+serratiopeptidase relieves pain and inflammation in arthritic conditions with the benefit of increased antibiotic penetration and micro-circulation at the injury site. Serratiopeptidase present in Diclofenac+serratiopeptidase is a proteolytic enzyme which helps in the breakdown of insoluble protein (fibrin) a by-product of blood clots into smaller units. It also causes thinning of the fluids in the body as a result of injury, thereby making fluid drainage smoother in the swollen tissue.

Directions for Use

Swallow the medicine as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Diclofenac+serratiopeptidase

  • Stomach ache

  • Diarrhoea

  • Nausea (feeling sick)

  • Indigestion

Drug Warnings

Consumption of alcohol should be avoided during the treatment with Diclofenac+serratiopeptidase as it may lead to an increase in the risk of liver damage. Patients with a stomach ulcer, gastric bleeding, severe heart failure, stroke, and hypertension (high blood pressure), should not take Diclofenac+serratiopeptidase. Besides this, it should be avoided during the last trimester of pregnancy, unless there are compelling reasons for doing so. If you have a severe allergy to pain killers and, complications like asthma, rhinitis, angioedema (swelling under the skin) or skin rashes, immediately stop taking Diclofenac+serratiopeptidase. Do not drive or operate heavy machinery as intake of Diclofenac+serratiopeptidase may cause dizziness. Patients who had recently undergone heart bypass surgery should take Diclofenac+serratiopeptidase with caution and only under medical supervision. Use of Diclofenac+serratiopeptidase is contraindicated in kidney failure patients or who are undergoing dialysis.

Drug Interactions

Drug-Drug Interaction: Drugs containing pain killers (nimesulide, oxyphenbutazone, metamizole), anti-cancer (methotrexate), lithium, iodine, and blood clotting agents (warfarin) should not be taken with Diclofenac+serratiopeptidase as they can worsen your condition.

Drug-Food Interaction: Drinking alcohol should be avoided while taking Diclofenac+serratiopeptidase as it can cause unpleasant effects.

Drug-Disease Interaction: People with peptic ulcer, gastric bleeding, severe heart failure, stroke, ulcerative colitis, Crohn's disease, alcoholism, and high blood pressure should avoid intake of Diclofenac+serratiopeptidase. Please seek medical advice.

Drug-Drug Interactions Checker List:

  • NIMESULIDE
  • OXYPHENBUTAZONE
  • METAMIZOLE
  • METHOTREXATE
  • WARFARIN
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      You are recommended not to consume alcohol along with Diclofenac+serratiopeptidase to avoid unpleasant side-effects.

    • Safety Warning

      Pregnancy

      caution

      Please inform your doctor if you are pregnant or planning to become pregnant before taking Diclofenac+serratiopeptidase.

    • Safety Warning

      Breast Feeding

      caution

      Diclofenac+serratiopeptidase may pass into the breast milk. Consult your doctor for more information on this if you are a breastfeeding mother.

    • Safety Warning

      Driving

      caution

      Diclofenac+serratiopeptidase may affect driving as it causes dizziness. Drive or operate machinery only when you are alert.

    • Safety Warning

      Liver

      caution

      Diclofenac+serratiopeptidase to be taken with caution, especially if you have a history of liver diseases/conditions. Dose may have to be adjusted by your doctor.

    • Safety Warning

      Kidney

      caution

      Diclofenac+serratiopeptidase to be taken with caution if you have a history of kidney diseases/conditions. Dose may have to be adjusted by your doctor.

    • Safety Warning

      Children

      caution

      Diclofenac+serratiopeptidase is not recommended for children under 10 years of age. For them dose has to be adjusted and recommended by a child specialist only.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Include more glucosamine, chondroitin sulphate, Vitamin D, and calcium-enriched supplements. Besides this, turmeric and fish oils can help in reducing inflammation in the tissue.

    • Do not go for heavy exercise as it may increase your joint pain in arthritis. Instead you can do stretching, low impact aerobic exercise like walking on treadmill, bike riding and swimming. You can also strengthen your muscle strength by lifting light weights.

    • In chronic condition of arthritis or joint pain try to include fish like salmon, trout, tuna, and sardines. These fishes are enriched with omega-3 fatty acids that minimize level of chemical called cytokines, which ramp up inflammation.

    • Your sitting posture is important especially when have pain and inflammation conditions. Try to sit little as possible, and only for short time (10-15 min). Use back support like a rolled-up towel at the back of your curve to minimize pain. Keep your knees and hips at a right angle. Besides this, you can use a foot rest if required.

    Patients Concern

    Disease/Condition Glossary

    Pain can be temporary (acute) or lifelong (chronic) in nature. Acute pain is for short time caused by damage to the tissues of the muscle, bone, or organs. While, chronic pain lasts for life long caused due to nerve damage, osteoarthritis, and dental pain due to damage to the tooth nerve, infection, decay, extraction, or injury. There are different types of musculoskeletal pain caused due to soft tissue (muscle, tendon and ligaments) injury. Extreme tissue pain and inflammation caused due to sprains, strains, or trauma or post-surgery may require a prolonged amount of time to heal. There are different types of musculoskeletal pain caused due to soft tissue (muscle, tendon and ligaments) injury. Extreme tissue pain and inflammation are caused due to sprains, strains, trauma or post-surgery. These types of injuries may require a prolonged amount of time to heal.

    FAQs

    Diclofenac+serratiopeptidase is used in the treatment of pain and inflammation due to bone or soft tissue injury, resolution of postoperative inflammation, oedema (swollen tissue with fluid) and pain.

    Diclofenac+serratiopeptidase when taken by patients who are allergic to pain-killers can be harmful. It should also be avoided in person with history of heart failure, kidney or liver disease, stomach ulcers and high blood pressure.

    You should only take Diclofenac+serratiopeptidase if doctor has prescribed you. The maximum recommended dose of Diclofenac+serratiopeptidase is twice daily. Diclofenac+serratiopeptidase can be one in the morning and one in the evening.

    Rheutamoid arthritis is an autoimmune disease that causes chronic inflammation and pain of the joints.

    Ankylosing spondylitis is a arthritis of the spine which can lead to the fusion of the vertebrae, lead to pain and inflammation in the spine.

    Yes, Diclofenac+serratiopeptidase can cause stomach upset. So, it should be preferably taken with food to avoid it.

    Diclofenac+serratiopeptidase should be stored in a cool and dry place, away from direct sunlight. Keep the medicine out of reach of children.

    Diclofenac+serratiopeptidase is generally safe when used as directed by your doctor for short-term pain and inflammation relief. However, you should not use Diclofenac+serratiopeptidase if you have a stomach ulcer, gastric bleeding, severe heart failure, stroke, hypertension (high blood pressure), kidney failure, or if you are undergoing dialysis.

    Yes, you can stop taking Diclofenac+serratiopeptidase once your pain is relieved, but only after consulting your doctor. It is recommended to follow your doctor's advice on the duration and dosage of Diclofenac+serratiopeptidase, as stopping the medication too early could affect your recovery.

    Yes, the use of Diclofenac+serratiopeptidase can cause nausea and vomiting as side effects. Taking it with food may help prevent nausea. If you experience vomiting, try drinking small sips of water or other fluids frequently. If these symptoms persist, please consult your doctor.

    Yes, the use of Diclofenac+serratiopeptidase may cause dizziness as a side effect in some individuals. Avoid driving or operating machinery if you experience dizziness. If dizziness persists, please consult your doctor.

    Yes, Diclofenac+serratiopeptidase is contraindicated in patients who are allergic to any of its components, those with kidney failure, or those undergoing dialysis. It should not be taken by patients with a stomach ulcer, gastric bleeding, severe heart failure, stroke, or hypertension (high blood pressure). Also, it should be avoided during the last trimester of pregnancy. Please consult your doctor if you have any concerns while using Diclofenac+serratiopeptidase.

    No, Diclofenac+serratiopeptidase is not generally recommended for stomach pain. In fact, it may cause stomach upset, ulcers, or bleeding. If you have stomach pain, please consult your doctor for a proper diagnosis and treatment.

    Yes, long-term or high-dose use of Diclofenac+serratiopeptidase, a nonsteroidal anti-inflammatory drug (NSAID), can potentially damage the kidneys. Regular monitoring and caution are advised when using Diclofenac+serratiopeptidase, especially in individuals with existing kidney disease. Please consult your doctor before using Diclofenac+serratiopeptidase.

    Yes, Diclofenac+serratiopeptidase can be taken on an empty stomach, but it is generally advisable to take Diclofenac+serratiopeptidase with food to reduce the risk of side effects. Always follow your doctor's instructions when taking Diclofenac+serratiopeptidase.

    Diclofenac+serratiopeptidase is generally not recommended for children under 10 years of age unless prescribed by a doctor. Always consult a paediatrician before giving Diclofenac+serratiopeptidase to a child, as the dosage may need to be adjusted for them.

    Diclofenac+serratiopeptidase is intended for short-term use only, as it may potentially cause side effects such as gastrointestinal or cardiovascular issues. Always follow your doctor's advice regarding the duration and dosage.

    No, it is generally not recommended to consume alcohol while taking Diclofenac+serratiopeptidase as it may increase the risk of side effects, such as stomach irritation, ulcers, and bleeding. Your doctor may advise you to limit or avoid alcohol consumption while taking Diclofenac+serratiopeptidase.

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    Diclofenac+serratiopeptidase

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