DAPAGLIFLOZIN+SITAGLIPTIN
About
DAPAGLIFLOZIN+SITAGLIPTIN is used to treat type-2 diabetes mellitus. Type-2 diabetes mellitus (also known as non-insulin-dependent diabetes or adult-onset diabetes) is a medical condition in which blood glucose levels are above normal due to insulin deficiency, insulin resistance, or both.
DAPAGLIFLOZIN+SITAGLIPTIN contains Dapagliflozin (sodium-glucose cotransporter-2 inhibitors) and Sitagliptin (dipeptidyl peptidase-4 inhibitor). Dapagliflozin lowers blood glucose levels and increases the excretion of glucose in the urine. By increasing insulin levels and lowering glucagon levels (the hormone that raises blood glucose levels), sitagliptin decreases the amount of glucose the liver produces. Thus, DAPAGLIFLOZIN+SITAGLIPTIN helps control blood sugar levels.
DAPAGLIFLOZIN+SITAGLIPTIN may cause side effects such as diarrhoea, hypoglycaemia, headache, nausea, and vomiting. These effects do not require medical attention and gradually resolve over time. Inform your doctor if any of these side effects persist or bother you. Take DAPAGLIFLOZIN+SITAGLIPTIN as prescribed by your doctor.
DAPAGLIFLOZIN+SITAGLIPTIN should be avoided if you are allergic to any of the components in it. Inform your doctor if you are pregnant or breastfeeding. Let your doctor know about all the medicines you are taking and your health condition to rule out any unpleasant side effects/interactions.
Uses of DAPAGLIFLOZIN+SITAGLIPTIN
Medicinal Benefits
DAPAGLIFLOZIN+SITAGLIPTIN is a combination medicine containing Dapagliflozin and Linagliptin as active ingredients. Dapagliflozin helps in removing excess sugar from the body via urine. Linagliptin works by decreasing the hormones that raise blood glucose levels and increasing insulin release from the pancreas. Together, DAPAGLIFLOZIN+SITAGLIPTIN helps control blood sugar levels.
Directions for Use
Storage
Side Effects of DAPAGLIFLOZIN+SITAGLIPTIN
- Stomach upset
- Hypoglycaemia (low blood sugar levels)
- Nausea
- Vomiting
- Diarrhea
- Headache
- Constipation
- Dizziness
- Runny nose
- Sore throat
In-Depth Precautions and Warning
Drug Warnings
Do not take DAPAGLIFLOZIN+SITAGLIPTIN if you are allergic to any of its components. Inform your doctor about all the medicines you are taking and your health condition to rule out any unpleasant side effects. Inform your doctor if you have any liver/kidney disease, heart problems, and hypertension before taking DAPAGLIFLOZIN+SITAGLIPTIN. DAPAGLIFLOZIN+SITAGLIPTIN is not recommended for children as safety and effectiveness have not been established. Avoid alcohol consumption while taking DAPAGLIFLOZIN+SITAGLIPTIN as it might cause unpleasant side effects. It is unknown whether DAPAGLIFLOZIN+SITAGLIPTIN can be given to pregnant women or breastfeeding mothers. Hence, inform your doctor if you are pregnant or breastfeeding. It is not recommended for use in children below 18 years of age.
Drug Interactions
Drug-Drug Interactions: DAPAGLIFLOZIN+SITAGLIPTIN may interact with anti-diabetic (insulin glargine), diuretics (furosemide), hormone (levothyroxine) and corticosteroids.
Drug-Food Interactions: Avoid alcohol consumption.
Drug-Disease Interactions: Inform your doctor if you have hypoglycaemia (low blood sugar levels), heart problems and liver/kidney disease.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid consumption of alcohol during treatment with DAPAGLIFLOZIN+SITAGLIPTIN as it may cause serious side effects.
Pregnancy
consult your doctorIf you are pregnant or planning pregnancy, inform your doctor before starting treatment with DAPAGLIFLOZIN+SITAGLIPTIN. Your doctor may prescribe this medicine if the benefits outweigh the risks.
Breast Feeding
consult your doctorLimited data is available on the effect of DAPAGLIFLOZIN+SITAGLIPTIN on breastfeeding. Hence, if you are a nursing mother, inform your doctor before taking DAPAGLIFLOZIN+SITAGLIPTIN. Your doctor may prescribe this medicine if the benefits outweigh the risks.
Driving
cautionDAPAGLIFLOZIN+SITAGLIPTIN may occasionally cause dizziness. Hence, drive only if you are alert after taking this medicine.
Liver
consult your doctorIf you have a pre-existing or a history of liver disease, inform your doctor before taking DAPAGLIFLOZIN+SITAGLIPTIN. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.
Kidney
consult your doctorIf you have a pre-existing or a history of kidney disease, inform your doctor before taking DAPAGLIFLOZIN+SITAGLIPTIN. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.
Children
unsafeDAPAGLIFLOZIN+SITAGLIPTIN is not recommended for use in children below 12 years of age as the safety and efficacy are not established.
Habit Forming
Diet & Lifestyle Advise
- Eat foods rich in healthy carbohydrates and fibre, fruits, whole grains, and vegetables.
- Try eating food at regular intervals. Do not skip meals. Also, try not to overeat.
- Follow a healthy diet and walk/exercise for at least 45 minutes.
- Maintain a healthy weight by exercising regularly.
- Rest properly and avoid stress by doing meditation or yoga.
Special Advise
- Regularly monitor blood glucose levels while taking DAPAGLIFLOZIN+SITAGLIPTIN.
- Try not to skip any doses and take DAPAGLIFLOZIN+SITAGLIPTIN for as long as your doctor has prescribed it for you.
- Always carry a sugary food such as candy or fruit juice and consume them if you experience hypoglycaemia.
Patients Concern
Disease/Condition Glossary
Type-2 diabetes mellitus: It is also known as non-insulin-dependent diabetes. It is a chronic or lifelong disease that keeps the body from utilizing insulin properly. Diabetes is a medical condition in which blood glucose levels are above normal. People with type 2 diabetes either do not produce enough insulin, or the produced insulin cannot perform its function in the body (insulin resistance).
FAQs
DAPAGLIFLOZIN+SITAGLIPTIN is used to treat type-2 diabetes mellitus. Type-2 diabetes mellitus (also known as non-insulin-dependent diabetes or adult-onset diabetes) is a medical condition in which blood glucose levels are above normal due to insulin deficiency, insulin resistance, or both.
Low-fibre diets, high-fat diets, sugary diets, obesity, smoking, stress, lack of exercise, age, genetic factors, and certain medical conditions are the common causes of diabetes.
DAPAGLIFLOZIN+SITAGLIPTIN is a combination medicine containing Sitagliptin that enhances glucose-mediated insulin secretion, thereby reducing fasting and post-prandial blood sugar concentrations. Dapagliflozin lowers blood glucose levels and increases the excretion of glucose in the urine. By increasing insulin levels and lowering glucagon levels (the hormone that raises blood glucose levels), sitagliptin decreases the amount of glucose the liver produces.
