Codeine
About Codeine
Codeine belongs to the class of medications called ‘analgesics’ used to treat acute or short-term painful conditions in adults. Pain is a widely used term to describe an unpleasant feeling or discomfort. It ranges from mild to severe. The severity of the pain depends on the underlying condition. Depending on pain duration, it is also classified as acute (short-term) and chronic (long-term). Acute pain, if left untreated, can result in chronic pain in some conditions.
It contains codeine, which belongs to a class of medicines called opioids, which are ‘pain relievers’. It also works by preventing pain signals from being transmitted along the nerves to the brain.
You should take this medicine exactly as the doctor prescribed it. The common side-effects of Codeine are dizziness, drowsiness, headache, feeling sick (nausea), constipation, vomiting, dry mouth, abdominal pain, low body temperature, blurred or double vision, low blood pressure, and slow or fast heartbeat. These side effects are usually mild and temporary. However, if these side effects persist or worsen, inform your doctor immediately.
Codeine is not recommended to take Codeine if you are allergic to any contents of it. Before taking Codeine, inform your doctor if you have if you are suffering a head injury or increased pressure in the brain, severe breathing problems, severe liver, kidney, heart failure, history of heart attack or stroke, acute alcoholism, diarrhoea due to inflammation of the bowel or poisoning and problems with blood circulation. Codeine is a habit-forming drug, so there is a risk of dependence on Codeine. So, before stopping Codeine, contact a doctor as it may cause withdrawal symptoms like anxiety, increased heart rate, tremors, or general unwell feelings. It is not recommended for children, pregnant women, and breastfeeding mothers. It should be used with caution in elderly patients. Avoid the consumption of alcohol as it may increase the risk of side effects. Codeine may cause dizziness or drowsiness, so do not drive or operate heavy machinery if you are not fully alert.
Uses of Codeine
Medicinal Benefits
Codeine is used to provide relief from acute painful conditions in adults. It contains codeine, which belongs to a class of medicines called opioids, which are ‘pain relievers’. Codeine works by preventing pain signals from being transmitted along the nerves to the brain.
Directions for Use
Storage
Side Effects of Codeine
- Confusion
- Dizziness
- Drowsiness
- Tiredness
- Changes in mood
- Nightmares
- Depression
- Restlessness/excitement
- Headache
- Hallucinations (seeing, feeling, or hearing things that are not there)
- Feeling sick (nausea)
- Constipation
- Vomiting
- Dry mouth
- Abdominal pain
- Low body temperature
- Blurred or double vision
- Palpitations
- Low blood pressure
- Slow or fast heartbeat
Drug Warnings
Codeine is not recommended to take Codeine if you are allergic to any contents of it. Before taking Codeine, inform your doctor if you have if you are suffering a head injury or increased pressure in the brain, severe breathing problems, severe liver, kidney, heart failure, history of heart attack or stroke, acute alcoholism, diarrhoea due to inflammation of the bowel or poisoning and problems with blood circulation. Codeine is a habit-forming drug, so there is a risk of dependence on Codeine. So, before stopping Codeine, contact a doctor as it may cause withdrawal symptoms like anxiety, increased heart rate, tremors, or general unwell feelings. It is not recommended for children, pregnant women, and breastfeeding mothers. It should be used with caution in elderly patients. Avoid the consumption of alcohol as it may increase the risk of side effects. Codeine may cause dizziness or drowsiness, so do not drive or operate heavy machinery if you are not fully alert. Taking monoamine oxidase inhibitors (MAOI) and Codeine is not recommended simultaneously. If you notice chest pain, breathing difficulties, weakness, or slurry speech, STOP the medication and immediately inform your doctor.
Drug Interactions
Drug-Drug Interactions: Codeine is known to interact with some medicines used to relieve anxiety (lorazepam, diazepam, alprazolam), anticonvulsant medication (pregabalin), an atypical antipsychotic medication (quetiapine), narcotic analgesic medication (oxycodone), and medicines used to treat depression (linezolid, moclobemide, selegiline)
Drug-Food Interactions: Avoid the consumption of alcohol as it may increase dizziness and the risk of gastrointestinal bleeding.
Drug-Disease Interactions: Codeine should not be used in patients with impaired GI motility, infectious diarrhoea, liver disease, prematurity, acute alcohol intoxication, drug dependence, gastrointestinal obstruction, hypotension, intracranial pressure and respiratory depression.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeConsumption of alcohol increases the risk of side effects, such as dizziness, drowsiness, liver damage, and bleeding in the stomach.
Pregnancy
cautionCodeine should not be taken until prescribed. Your doctor will weigh the benefits and potential risks before prescribing them. Please consult your doctor.
Breast Feeding
cautionCodeine should not be taken until prescribed. Your doctor will weigh the benefits and potential risks before prescribing them. Please consult your doctor.
Driving
cautionCodeine may cause dizziness, drowsiness, confusion, or hallucinations, so do not drive or operate heavy machinery if you are not fully alert.
Liver
cautionCodeine to be taken with caution, especially if you have a history of liver diseases/conditions. Your doctor may have to adjust the dose.
Kidney
cautionConsult your doctor, as a dose adjustment might be needed when using Codeine in patients with kidney disease.
Children
unsafeCodeine is not recommended for children below 12 years of age.
Habit Forming
Diet & Lifestyle Advise
- Physical activity helps strengthen muscles and relieves joint stiffness. Gentle activities like 20-30 minutes of walking or swimming would be helpful.
- Performing yoga may also help in improving joint flexibility and pain management.
- Maintain a healthy weight by performing regular low-strain exercises and eating nutritious food.
- Get adequate sleep, as resting the muscles can help reduce inflammation and swelling.
- Follow heat or cold therapy, and apply a cold or hot compress on the joints for 15-20 minutes regularly.
- Acupuncture, massage, and physical therapy may also be helpful.
- Eat foods rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
- Foods containing flavonoids, such as soy, berries, broccoli, grapes, and green tea, help reduce inflammation.
- Avoid smoking and alcohol consumption.
Special Advise
- Do not stop taking Codeine abruptly. It may cause withdrawal reactions such as restlessness, difficulty speaking, agitation, anxiety, palpitations (pounding or racing heart), increased blood pressure, loss of appetite, diarrhoea, tremors, and sweating. The doctor gradually reduces the dose before completely stopping the medicine.
- Please do not increase the dose or use it frequently without consulting your doctor, leading to addiction.
- It is not recommended to take monoamine oxidase inhibitors (MAOI) and Codeine simultaneously. You should wait 14 days after discontinuing MAOI before using the Codeine.
- Inform your doctor that you are taking Codeine before undergoing any surgery, medical or dental treatment.
Patients Concern
Disease/Condition Glossary
Pain: Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain may be dull or sharp, and it might be constant or long-term (chronic) or short-term (acute). The tolerance level of pain might vary from person to person. Pain can be generalized (overall body aches) or localized (affecting a specific body area). Pain can be considered a good thing as it helps us know something is wrong in the body and helps diagnose the condition. The common causes of pain include headache, muscle strain, cramps, cuts, bone fractures, and arthritis.
FAQs
Codeine is used to relieve pain.
Codeine contains codeine, which belongs to a class of medicines called opioids, which are ‘pain relievers’. And it works by preventing pain signals transmission along the nerves to the brain.
No, consult a doctor before taking Codeine for any condition. It is not advised to use Codeine without a doctor's recommendation.
Do not take Codeine with alprazolam as co-administration may increase adverse effects such as sedation, respiratory depression, coma, and death. However, please consult a doctor before taking Codeine with other drugs.
Codeine is excreted in breast milk and may cause drowsiness, breathing problems, or death in a nursing baby. Therefore, if you are breastfeeding, please inform your doctor before taking Codeine. Your doctor will weigh the benefits and potential risks before prescribing it.
If you are addicted to codeine, you may want to take it more often or feel agitated if you delay taking a dose for any reason.