Clotrimazole+tinidazole
About Clotrimazole+tinidazole
Clotrimazole+tinidazole is used to treat vaginal discharge. Bacterial vaginosis, yeast infections, and sexually transmitted infections (STIs) are all potential causes of vaginal discharge infections. The discharge may have an odd colour, smell, or consistency.
Clotrimazole+tinidazole contains two medicines, Clotrimazole and Tinidazole. Clotrimazole is an antifungal agent primarily used for the treatment of fungal infections caused by vaginal candidiasis (yeast infection) which works by disrupting the cell membrane of fungi, inhibiting the synthesis of ergosterol, which is an essential component of fungal cell membranes. This leads to fungal cell death. Tinidazole is an antibiotic or antiprotozoal which kills amoeba and parasites by disrupting the DNA of microorganisms, thereby stopping the growth of certain bacteria and protozoa. Thus, Clotrimazole+tinidazole helps treat fungal infections.
Use Clotrimazole+tinidazole as prescribed by your doctor. It is for vaginal use only. Avoid contact with the eyes, nose, or mouth. Wash thoroughly with water in case of accidental contact. In some cases, you may experience some common side effects such as a burning sensation, irritation, itching in the vaginal area and redness or peeling of the skin. However, these side effects are mild and temporary. Consult your doctor if the side effects persist or worsen.
Before using Clotrimazole+tinidazole, inform your doctor if you take other azole antifungal or lincomycin antibiotic medications. Otherwise, using other antifungal or antibacterial medicines with Clotrimazole+tinidazole may lead to overdose and toxicity. Let your doctor know if you have any liver, kidney, and gastrointestinal conditions (diarrhoea and colitis, inflammation of the colon), asthma, hay fever, eczema, diabetes, and vulnerable system problems (HIV- AIDS). Also, inform your doctor if you are pregnant, planning pregnancy or breastfeeding before using Clotrimazole+tinidazole.
Uses of Clotrimazole+tinidazole
Medicinal Benefits
Clotrimazole and Tinidazole are the two medications which compose Clotrimazole+tinidazole, which is used in the treatment of vaginal discharge such as bacterial vaginosis (BV), candidiasis, and Trichomoniasis. Clotrimazole is an imidazole antifungal drug that damages and leaks the fungal cell membrane, preventing fungal growth. Tinidazole is an antibiotic or antiprotozoal which kills amoeba and parasites by disrupting the DNA of microorganisms, thereby stopping the growth of certain bacteria and protozoa. Thereby Clotrimazole+tinidazole treats vaginal infections caused by bacteria, yeast, and parasites, including white discharge, itchiness, and inflammation in the genitourinary area.
Directions for Use
Check the label for directions to use. Wash and dry the vaginal area. Lie on your back and gently insert the prescribed amount of cream into the vagina using the applicator, usually before bedtime, to reduce leakage.
Storage
Side Effects of Clotrimazole+tinidazole
- Burning sensation
- Irritation
- Itching in the vaginal area
- Redness or peeling of skin.
Drug Warnings
Before using Clotrimazole+tinidazole, please let your doctor know if you are taking any prescription or over-the-counter medications, including vitamin and herbal supplements; if you have allergies to Clotrimazole+tinidazole or any of its ingredients, if you have liver, kidney, or gastrointestinal diseases (diarrhoea and colitis, inflammation of the colon), if you have any allergies (asthma, hay fever, eczema), if you have diabetes, if you use other azole antifungal medications, it is recommended that you use Clotrimazole+tinidazole under your doctor's supervision the mineral oil additive in Clotrimazole+tinidazole, clotrimazole, may reduce the effectiveness of rubber products (e.g., latex condoms, diaphragms, cervical caps); and also let your doctor know if you are breastfeeding, pregnant or planning pregnancy.
Drug Interactions
Drug-Drug Interaction: Clotrimazole+tinidazole may interact with anaesthetic agents/skeletal muscle relaxants (atracurium, cisatracurium, doxacurium, mivacurium, pancuronium, pipecuronium, rapacuronium, rocuronium, vecuronium, succinylcholine, tubocurarine, and metocurine) and respiratory drugs (budesonide, formoterol).
Drug-Food Interaction: No interaction found/established.
Drug-Disease Interaction: Before taking Clotrimazole+tinidazole, let your doctor know if have any liver, kidney, and gastrointestinal diseases (diarrhoea and colitis, an inflammation of the colon), allergic conditions (asthma, hay fever, eczema), diabetes, and immune system problems (HIV-AIDS).
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
safe if prescribedNo interaction found/established.
Pregnancy
consult your doctorThere are limited studies on how Clotrimazole+tinidazole affects the unborn baby during pregnancy. It is advised to consult your doctor before using Clotrimazole+tinidazole.
Breast Feeding
consult your doctorThere is limited data on how Clotrimazole+tinidazole affects breastfeeding infants. However, systemic absorption of Clotrimazole+tinidazole is negligible after topical and vaginal administration. Consult your doctor if you have any concerns.
Driving
safe if prescribedNo interaction found/established.
Liver
cautionIf you have pre-existing liver disease, inform your doctor before using Clotrimazole+tinidazole.
Kidney
consult your doctorIf you have pre-existing kidney disease, inform your doctor before using Clotrimazole+tinidazole.
Children
unsafeClotrimazole+tinidazole is not recommended for children below 12 years of age. Do not give this medicine to your child without consulting your doctor.
Habit Forming
Diet & Lifestyle Advise
• Avoid frequent douching to maintain the natural moisture in the vagina.
• Use mild soap and prefer warm baths
• Avoid harsh products on your skin.
• Reduce stress, eat well, stay hydrated, exercise frequently, and get enough sleep.
• Limit or stay away from caffeine and alcohol.
Special Advise
- Ask your partner to use condoms during sexual intercourse to help prevent the spread of sexually transmitted illnesses like gonorrhea.
- Practising good hygiene and regularly cleaning and washing the genitourinary area with an anti-infective wash is advised.
- To avoid vaginal irritation and inflammation, try wearing cotton pantyhose and underwear with a cotton crotch.
Patients Concern
Disease/Condition Glossary
Bacterial vaginosis: A greyish-white discharge with a foul odour frequently described as fishy. The odour may become more evident after intercourse.
Yeast infection: It is characterized by a thick, white discharge similar to cottage cheese and irritation.
Trichomoniasis: It causes a greenish-yellow discharge that might be foamy.
Chlamydia or gonorrhea: A discharge that may cause pelvic pain or bleeding.
FAQs
Clotrimazole+tinidazole is used in the treatment of vaginal discharge caused by bacteria (bacterial vaginosis), yeast infection (candidiasis), and parasitic infections (Trichomoniasis).
Clotrimazole+tinidazole Clotrimazole and Tinidazole. Clotrimazole is an antifungal agent primarily used for the treatment of vaginal discharge caused by vaginal candidiasis (yeast infection) which works by disrupting the cell membrane of fungi, inhibiting the synthesis of ergosterol, which is an essential component of fungal cell membranes. This leads to fungal cell death. Tinidazole is an antibiotic or antiprotozoal which kills amoeba and parasites by disrupting the DNA of microorganisms, thereby stopping the growth of certain bacteria and protozoa. Together used for the treatment of vaginal discharge.
If you have any liver, kidney, or gastrointestinal disorders (diarrhoea, colitis, or inflammation of the colon), allergies (asthma, hay fever, or eczema), diabetes, or immune system issues (HIV-AIDS), you should use Clotrimazole+tinidazole carefully and with a doctor's advice.
Do not stop using Clotrimazole+tinidazole even if you feel better until your doctor-advised course is finished. Your symptoms may improve before the infection is completely cured.
Bacterial infections, yeast infections, parasitic infections, vaginal atrophy after menopause and irritants like body wash/soap/perfumes/vaginal contraceptive devices are some of the common causes of vaginal discharge.
Your doctor might ask you a few questions about your sexual health, like your history of past vaginal infections or if you have had any sexually transmitted infections (STIs) like gonorrhoea. Besides this, your doctor might also perform a pelvic exam by collecting a vaginal discharge sample.
Store Clotrimazole+tinidazole at room temperature. Away from sunlight and moisture. Keep out of reach of children.
The common side effects of Clotrimazole+tinidazole are burning sensation, irritation, itching in the vaginal area, redness or peeling of skin. If any of these side effects persist or worsen, please consult your doctor.
