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Atorvastatin+aspirin

About Atorvastatin+aspirin

Atorvastatin+aspirin is used for the prevention of heart attack and stroke. A heart attack generally refers to a blocked flow of blood to the heart due to the blockage of the arteries. The blockage is most often a buildup of fat, cholesterol and other substances, which form a plaque in the arteries that feed the heart (coronary arteries).

Atorvastatin+aspirin is composed of rosuvastatin and aspirin. This medicine reduces the bad cholesterol (also known as low-density lipoproteins or LDL), and triglycerides (TG). It also collectively prevents the formation of clots in the blood vessels. Together, Atorvastatin+aspirin helps to reduce the risk of heart attack, stroke, and heart-related chest pain (angina).

In some cases, you may experience headache, ankle swelling (oedema), dark urine, muscle weakness, slow heart rate, dizziness, and nausea. Most of these side effects of Atorvastatin+aspirin do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Take Atorvastatin+aspirin with or without food. Your doctor will advise you on how often you take your medicine based on your medical condition. Try not to stop taking this medicine on your own. Do not chew, break, or crush the medicine.

Avoid taking Atorvastatin+aspirin if you are allergic to it. Stopping Atorvastatin+aspirin abruptly may worsen your condition and increase your risk of future heart attack. Let your doctor know if you have any active liver disease, bleeding issues, muscle problems, are pregnant or planning to become pregnant or are breastfeeding. Patients should inform the doctor that they are taking Atorvastatin+aspirin before any surgery is scheduled or any new medicine is taken.

Uses of Atorvastatin+aspirin

Atorvastatin+aspirin is used in prevention of heart attack and stroke. The detailed uses of Atorvastatin+aspirin are as follows:
• Cardiovascular Protection: Atorvastatin+aspirin is frequently prescribed to prevent blood clots in individuals at high risk of heart attacks or strokes.
• Anti-inflammatory Effects: Atorvastatin+aspirin is known for its ability to reduce inflammation associated with various medical conditions.
• Management of Angina: Atorvastatin+aspirin supports the management of angina symptoms by enhancing blood flow and reducing the heart's workload.
• Post-surgical Care: Atorvastatin+aspirin is administered after certain surgeries to lower the risk of thromboembolic events, promoting smoother recovery.

Medicinal Benefits

  • Atorvastatin+aspirin is composed of two medicines: Atorvastatin and Aspirin.
  • Atorvastatin is an antilipemic agent (cholesterol-lowering) which works by blocking liver enzymes, causing the liver to make less cholesterol.
  • It also lowers the bad cholesterol (low-density lipoprotein or LDL) levels and increases good cholesterol levels (high-density lipoprotein or HDL) in the blood.
  • Aspirin is an anti-platelet drug that decreases blood clot's formation by preventing the platelets from clubbing together.
  • Atorvastatin+aspirin helps in the free flow of blood, thereby preventing a heart attack, stroke and other peripheral vascular diseases.
  • Atorvastatin+aspirin reduces the risk of coronary events, such as heart attack, stroke and angina (chest pain). 

Directions for Use

  • Atorvastatin+aspirin can be taken with or without food as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Atorvastatin+aspirin as a whole with a glass of water.
  • Do not crush, break, or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Atorvastatin+aspirin

  • Headache
  • Ankle swelling (oedema)
  • Dark urine
  • Muscle weakness
  • Slow heart rate
  • Dizziness
  • Nausea

Drug Warnings

  • Let your doctor know if you are highly sensitive to atorvastatin or aspirin, have any active liver disease, active bleeding issues (like peptic ulcer, brain haemorrhage), are pregnant or planning to become pregnant, or are breastfeeding.
  • The patient should inform the doctor that they are taking Atorvastatin+aspirin before any surgery is scheduled or any new medicine is taken.
  • Atorvastatin present in Atorvastatin+aspirin is a pregnancy category X drug so it is contraindicated in pregnant women.
  • Atorvastatin+aspirin contains atorvastatin, which can cause muscle problems like myopathy and rhabdomyolysis. So, any signs of muscle pain, tenderness, or weakness during the initial months of the treatment should be closely monitored.
  • Safety and effectiveness of Atorvastatin+aspirin have not been established, so its use should be avoided in paediatric patients or children less than 12 years of age.
  • Abrupt discontinuation of Atorvastatin+aspirin may lead to the occurrence of cardiovascular events like heart attack, stroke, and angina (heart-related chest pain). Hence, you should consult a doctor before stopping the dose of Atorvastatin+aspirin.
  • Do not drive or operate machinery if you experience dizziness or drowsiness while using Atorvastatin+aspirin.
  • Please do not consume alcohol since it may worsen the side effects like dizziness and increased blood pressure. 

Drug Interactions

Drug-Drug Interaction: Atorvastatin+aspirin may interact with antibiotics (clarithromycin), anti-HIV drugs (ritonavir, lopinavir, darunavir, atazanavir, indinavir) and antifungal (itraconazole), blood thinners (warfarin, heparin), anti-arthritis drug (colchicine), heart-related medicine (digoxin), and immune system affecting drug (cyclosporine).

Drug-Food Interaction: Alcoholic beverages and grapefruit or its juice intake should be avoided with Atorvastatin+aspirin as it may interact with Atorvastatin+aspirin to produce unpleasant side effects.

Drug-Disease Interaction: Atorvastatin+aspirin should not be given to the patients with active liver disease, active bleeding issues (like peptic ulcer, brain haemorrhage), muscle problems or musculoskeletal problems (myopathy, rhabdomyolysis), asthma, and purpura (blood leakage under the skin).

Drug-Drug Interactions Checker List:

  • CLARITHROMYCIN
  • RITONAVIR
  • LOPINAVIR
  • DARUNAVIR
  • ATAZANAVIR
  • INDINAVIR
  • ITRACONAZOLE
  • WARFARIN
  • HEPARIN
  • COLCHICINE
  • DIGOXIN
  • CYCLOSPORINE
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      Atorvastatin+aspirin should not be taken until prescribed if you are taking alcohol. Keep your doctor informed if you drink alcohol. Drinking alcohol with Atorvastatin+aspirin may potentiate gastric or stomach bleeding and ulcer symptoms. So, try to avoid or limit consumption of alcoholic beverages while using Atorvastatin+aspirin.

    • Safety Warning

      Pregnancy

      unsafe

      Atorvastatin+aspirin contains Atorvastatin which is a pregnancy category X medicine. So, it is not recommended for the pregnant mother, or those who are planning to get pregnant. In an extreme case, your doctor will decide whether Atorvastatin+aspirin can be given or not.

    • Safety Warning

      Breast Feeding

      consult your doctor

      Take Atorvastatin+aspirin only when prescribed, as it is known to pass on in a limited quantity via breast milk to the child. Contact your doctor before using Atorvastatin+aspirin.

    • Safety Warning

      Driving

      caution

      Drive with caution as, Atorvastatin+aspirin can cause blurry vision and may affect your driving ability.

    • Safety Warning

      Liver

      caution

      Atorvastatin+aspirin to be taken with caution, especially if you have a history of liver diseases/conditions. Dose can be adjusted by your doctor.

    • Safety Warning

      Kidney

      caution

      Atorvastatin+aspirin to be taken with caution, especially if you have a history of kidney diseases/conditions. Dose may have to be adjusted by your doctor.

    • Safety Warning

      Children

      unsafe

      Atorvastatin+aspirin is not recommended for children below the age of 16 years. The safety and effectivenss of Atorvastatin+aspirin has not been established in children due to limited testing of this drug on children by competent authorities across the world.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Eat a healthy diet, especially rich in soluble fibre like beans, legumes, whole grains, flax, apples, and citrus fruits.
    • Try to replace most of your saturated fats with unsaturated fats that can reduce total cholesterol and LDL cholesterol in a short span of time. Foods like avocados, olive oil, fatty fish, and nuts contain lots of heart-healthy unsaturated fats, so it’s beneficial to eat them regularly.
    • Try to adopt a Mediterranean-style diet rich in olive oil, fruits, vegetables, nuts, whole grains, and fish, and low in red meat and most dairy.
    • Try to give priority to more fruits and veggies in your daily meal as these contain antioxidants, which help to lower LDL - low density lipoprotein (bad cholesterol)
    • Minimize the intake of added sugar. The American Heart Association (ADA) recommends that one should not eat more than 100 calories (25 grams) of added sugar for women and children and no more than 150 calories (37.5 grams) for men every day.
    • As a precautionary measure, do not consume alcohol and quit smoking.

    Patients Concern

    Disease/Condition Glossary

    Atherosclerosis occurs when fats, cholesterol and other substances known as plaque deposits on your artery walls that restrict blood flow. This plaque formation triggers blood clots, narrows the artery's size and makes it hardened. This, in turn, can lead to various heart complications like heart attack, heart-related chest pain (angina) and stroke. However, it can also affect the arteries of the body apart from the heart.

    FAQs

    Atorvastatin+aspirin is used for the prevention of heart attack and stroke. It lowers bad cholesterol levels and increases good cholesterol levels.

    Yes, the use of Atorvastatin+aspirin can cause dizziness in some patients. They may experience symptoms such as feeling of fainting, weakness, or lightheadedness. In case you experience such symptoms, it is better to rest for some time until you feel better.

    Usually Atorvastatin+aspirin is prescribed for a long-term treatment ranging from weeks to months for treating heart-related conditions and disorders. However, taking it on your own for years without doctor's consent can be fatal. Hence, only take it as long as your doctor has prescribed it to you.

    Yes, Atorvastatin+aspirin is known to cause upset stomach. So, it should be taken with food so as to avoid discomfort. If even then, problem persists, please consult your doctor for best advise. In rare cases gastro intestinal bleeding can be observed due to blood thinning action of aspirin present in Atorvastatin+aspirin.

    Theres no strong evidence to suggest that taking Atorvastatin+aspirin will reduce fertility in either men or women. However, it is advisable to consult a doctor before taking it if youre likely to get pregnant or pregnant.

    Available Medicines for

    Atorvastatin+aspirin

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