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Amoxycillin

About Amoxycillin

Amoxycillin belongs to a group of anti-bacterial or antibiotics known as penicillin. Amoxycillin is used to prevent and treat different types of bacterial infections like chest infections (pneumonia, bronchitis), ear/nose/throat (ENT) infections, urinary tract infections, skin infections, leg ulcers, gum ulcers, dental infections, and pressure sores. Besides this, it is also used with various antibiotics like clarithromycin to treat stomach ulcers caused by H. Pyroli bacteria.

Amoxycillin contains Amoxycillin, which kills the bacterial cell by blocking the chemical (mucopeptides) released by the bacteria's outer layer (cell wall). In turn, Amoxycillin weakens and destroys the bacterial cell wall. It is a broad range of antibiotics that helps in fighting various types of bacteria. 

During the treatment with Amoxycillin, you may observe some common side effects like feeling sick (nausea) and diarrhoea. Most of these side effects do not require medical attention and are resolved over time. However, if these side effects persist, let your doctor know. 

Do not use Amoxycillin without doctor's advice if you have a skin reaction or irritation to any medicine. Do not use Amoxycillin in more than prescribed doses or longer duration as it may cause adverse effects. Keep your doctor informed about your health condition and all the medicines you take before taking Amoxycillin to rule out any side effects. Do not discontinue or abruptly stop the medication, as it may lead to antibiotic resistance, a condition in which bacteria become resistant to antibiotics.

Uses of Amoxycillin

Treatment of bacterial infections

Medicinal Benefits

Amoxycillin is a broad-spectrum antibiotic that helps treat various bacterial infections like ear, nose, or throat (ENT) infections, skin infections, genitourinary tract, and lower respiratory tract infections (LRTI) caused by susceptible bacteria. Amoxycillin is effective against gram-positive (S. pneumoniae) and gram-negative bacteria (E. coli, Haemophilus influenza, Neisseria gonorrhoea). Besides this, Amoxycillin also helps treat stomach ulcers caused by the H Pyroli bacteria. If combined with antibiotics like clarithromycin and acidity medicine like lansoprazole, it helps reduce the symptoms of duodenum ulcers. Amoxycillin can be safely prescribed and well-tolerated among adults, children, pregnant and nursing mothers.

Directions for Use

Tablet/Capsule: Take it with food to avoid stomach upset. Swallow it as a whole with a glass of water. Do not break, crush or chew it. Syrup: Shake the bottle well before use. Check the label for directions and take it in the dose prescribed by your doctor with the help of a measuring cup/dosing syringe/dropper provided by the pack.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Amoxycillin

  • Feeling sick (nausea)
  • Diarrhoea

Drug Warnings

Do not take Amoxycillin if you are allergic to any of its components. Taking Amoxycillin may cause antibiotic-induced diarrhoea in some cases. Penicillin antibiotics, blood thinners (warfarin, coumadin), uric acid-lowering drugs (allopurinol, probenecid), and anti-cancer or anti-arthritis drugs (methotrexate) may severely interact with Amoxycillin. Tell your doctor if you have chronic kidney disease or viral glandular fever (mononucleosis) before taking Amoxycillin. This medicine may lower the efficiency of oral birth control pills or contraceptive devices. An intake of Amoxycillin may alter some glucose urine tests like the copper reduction test report.

Drug Interactions

Drug-Drug Interactions: Amoxycillin interact with penicillin antibiotics, blood thinners (warfarin, coumadin), uric acid-lowering drugs (allopurinol, probenecid), and anti-cancer or anti-arthritis drug (methotrexate).

Drug-Food Interactions: Grapefruit juice and dietary supplements containing minerals like calcium may also work to dampen the effect of antibiotics.

Drug-Disease Interactions: Amoxycillin should not be given in the condition of colitis, glandular fever, and chronic kidney disease. Colitis is characterized by severe diarrhoea and abdominal cramps associated with the passage of mucous and blood via stool or vomiting.

Drug-Drug Interactions Checker List:

  • WARFARIN
  • COUMADIN
  • ALLOPURINOL
  • PROBENECID
  • METHOTREXATE
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      Do not drink too much while taking this medicine. Drinking a lot of alcohol may more likely to drowsiness, dizziness or sleepiness side effects.

    • Safety Warning

      Pregnancy

      caution

      Amoxycillin is a pregnancy category B drug. So, Amoxycillin can be safely taken by pregnant women if prescribed by the doctor.

    • Safety Warning

      Breast Feeding

      safe if prescribed

      Can safely give Amoxycillin to breastfeeding mothers.

    • Safety Warning

      Driving

      caution

      You may have side effects like dizziness after taking Amoxycillin that may make you unfit to drive. So, it is advisable not to drive or operate machinery until you are feeling well.

    • Safety Warning

      Liver

      safe if prescribed

      Amoxycillin can be safely taken in case of liver disease if prescribed by the doctor. Your doctor will weigh the benefits and any potential risks before prescribing Amoxycillin.

    • Safety Warning

      Kidney

      caution

      Take Amoxycillin with caution if you have severe kidney disease. Your doctor may reduce the dose of Amoxycillin in patients with severe renal impairment (GFR less than 30 mL/min).

    • Safety Warning

      Children

      safe if prescribed

      Can be Amoxycillin safely to children, dose to be adjusted and recommended by a child specialist only.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • After taking the full course of Amoxycillin, probiotics should be taken to restore some of the healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can restore the intestine's good bacteria stink.
    • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria, which helps stimulate their growth. Thus fibre foods may help restore healthy gut bacteria after taking a course of antibiotics. Whole grains like whole-grain bread, and brown rice, should be included in your diet.
    • Avoid taking too many calcium-enriched foods and drinks as it might affect the working of Amoxycillin.
    • Avoid intake of alcoholic beverages with Amoxycillin as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the Amoxycillin in fighting off infections.

    Patients Concern

    Disease/Condition Glossary

    Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect our body. It can target any body part and multiple very quickly. When you get infected with bacteria, you can experience generalized symptoms like fevers, chills, and fatigue. Bacteria are of various forms comprising commonly spherical, rod, and spiral-shaped. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. Few harmful bacteria that cause infections include Streptococcus, Staphylococcus, and E. coli. Anyone can become infected with a bacterial infection. But, people with weak immune systems or taking immunosuppressive medicine can make you more prone to bacterial infection.

    FAQs

    Amoxycillin is used to treat various bacterial infections like ear, nose, or throat (ENT) infections, skin infections, genitourinary tract, and lower respiratory tract infections (LRTI) caused by susceptible bacteria.

    Amoxycillin kills the bacterial cell by blocking the chemical (mucopeptides) released by the bacteria's outer layer (cell wall). In turn, Amoxycillin weakens and destroys the bacterial cell wall. It is a broad range of antibiotics that helps in fighting various types of bacteria.

    Amoxycillin belongs to the class of penicillin antibiotics. Amoxycillin is a broad-spectrum antibiotic effective against a wide range of bacteria. On the other hand, penicillin is a narrow-spectrum antibiotic effective against fewer bacteria.

    Do not use anti diarrhoeal until the doctor has prescribed you. You can drink plenty of fluids (electrolytes) to avoid dehydration. Besides this, you can also take prebiotics or probiotics to manage diarrhoea as it may help increase the number of good bacteria in the intestine, which aids indigestion.

    Try to stay well hydrated by drinking at least six glasses of water or other fluid per day. Always keep your bladder empty as much as possible by peeing regularly.

    After taking an antibiotic, you may need to wait for up to three hours to eat or drink any dairy products, including milk and butter, yoghurt, and cheese. Grapefruit juice and dietary supplements containing minerals like calcium may also work to dampen the effect of antibiotics.

    Do not stop using Amoxycillin even if you feel better. It should be strictly used as advised by your doctor to avoid the recurrence of symptoms and to worsen the disease.

    Amoxycillin may cause side effects such as nausea and diarrhoea. If these side effects persist or worsen, please consult your doctor.

    Amoxycillin can be used during pregnancy if prescribed by a doctor. Do not self-medicate, especially during pregnancy since there is limited safety information available on the use of Amoxycillin during pregnancy. Consult a doctor before taking Amoxycillin.

    You should not take Amoxycillin if you have or ever had cirrhosis, severe kidney or liver disease, adrenal gland failure, an electrolyte imbalance, or an allergy to Amoxycillin or sulfa drugs. Also, inform your doctor if you are pregnant, planning to conceive or are breastfeeding to avoid any harmful effect on your baby.

    Amoxycillin is effective if used in the dose and duration prescribed by your doctor. Do not stop taking Amoxycillin even if you see improvement in your condition as discontinuing Amoxycillin too early may cause symptoms to worsen or reoccur.

    If you forget to take a dose of Amoxycillin, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose in the prescribed time. Do not double the dose to make up for the missed one as this may increase the risk of side effects.

    Available Medicines for

    Amoxycillin

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