Allylestrenol
About Allylestrenol
Allylestrenol is used to prevent premature labour. Premature labour can start before 37 completed weeks of pregnancy and can be caused by premature rupture of membranes, high blood pressure during pregnancy (pre-eclampsia) and poor diet. A miscarriage is an unexpected loss of pregnancy before 20 weeks of pregnancy. It mostly happens during the first trimester, or the first three months, of the pregnancy.
Allylestrenol contains “Allylestrenol”, a progestin (female hormones) that works by modulating the immune response of the pregnant women to prevent rejection of the embryo and allows its attachment to the uterus and improve blood flow to the placenta. Allylestrenol prevents repeated miscarriage (pregnancy loss) and helps lower the risk of premature birth in pregnant women who have had a past premature delivery.
Take Allylestrenol as prescribed by your doctor. You are advised to take Allylestrenol for as long as your doctor has prescribed it for you. In some cases, you may experience certain common side effects, such as a change in weight, unwanted hair growth, menstrual disturbances, swelling over the body, fever, headache, and fatigue. Not everybody experiences these side effects. Most of the side effects of Allylestrenol do not require medical attention and gradually resolve over time. Talk to your doctor if you feel any discomfort while taking Allylestrenol.
Do not stop taking Allylestrenol abruptly without your doctor’s advice, as it may cause heavy bleeding. Before starting Allylestrenol, please inform your doctor if you have an allergy to Allylestrenol and any medicines. Tell your doctor before using Allylestrenol if you have had pre-eclampsia (high blood pressure during pregnancy), thromboembolic disorders (blood clot form in the blood), diabetes, depression, or epilepsy. Allylestrenol may cause dizziness, so be cautious while driving and operating machinery. Allylestrenol is not recommended for use in children. Inform your doctor if you are breastfeeding before taking Allylestrenol. Inform your doctor about all medicines you are taking and about your health condition to rule out any unpleasant side effects.
Uses of Allylestrenol
Medicinal Benefits
Allylestrenol contains “Allylestrenol” which is a progestin (female hormones) which is used in pregnant women who have a recurrent and threatened miscarriage (abortion) and pregnant women who have delivered a baby too early (preterm) in the past. It works by modulating the immune response of the pregnant women to prevent rejection of the embryo and allow its attachment to the uterus, and improve blood flow to the placenta. It also relaxes uterus muscles, thereby preventing premature labour. Allylestrenol prevents repeated miscarriage and helps lower the risk of premature birth in pregnant women who have had a past premature delivery. Also, Allylestrenol is used to treat intrauterine growth retardation (unborn baby is not growing at a normal rate), amenorrhoea (absence of menstrual periods due to lack of progesterone), irregular menses cycle, and premenstrual syndrome (symptoms include mood swings, tender breasts, food cravings, fatigue, irritability and depression that women can experience in the weeks before their menses period). On the other hand, Allylestrenol is effective in the treatment of hot flashes in postmenopausal women and benign prostatic hyperplasia (noncancerous increase in the size of the prostate gland) in men.
Directions for Use
Storage
Side Effects of Allylestrenol
- Change in weight
- Unwanted hair growth
- Menstrual disturbances
- Swelling over body
- Fever
- Headache
- Fatigue
Drug Warnings
You should not take Allylestrenol on your own without a doctor's advice. Before starting Allylestrenol, please inform your doctor if you have an allergy to any medicines. Do not take Allylestrenol if you have unusual vaginal bleeding that is not related to your pregnancy, liver disease, severe hypertension (high blood pressure), history of cancer of the breast, uterus or vagina. Tell your doctor before using Allylestrenol if you have had preeclampsia (high blood pressure during pregnancy), thromboembolic disorders (blood clot form in the blood), diabetes, depression, epilepsy. Do not stop taking Allylestrenol abruptly without your doctor’s advice as it may cause heavy bleeding. Let your doctor know if you are a breastfeeding mother. Your doctor will weigh the benefits and any potential risks before prescribing them to you. Allylestrenol is not recommended for children younger than 16 years old. Allylestrenol can cause dizziness and drowsiness. Use caution while driving a motor vehicle as dizziness or drowsiness may occur.
Drug Interactions
Drug-Drug Interaction: This Allylestrenol interacts with anti-epilepsy medicines (phenobarbital, phenytoin, primidone, carbamazepine), medicines used to treat fungal infections (griseofulvin, ketoconazole, itraconazole, posaconazole).
Drug-Food Interaction: Allylestrenol may interact with grapefruit and alcohol.
Drug-Disease Interaction: Allylestrenol should be taken with caution in breast cancer, thromboembolism (blood clot form in blood vessels), depression, diabetes, fluid retention (excess fluid builds up within the body), and kidney or liver disease.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionThere is not enough scientific data available for Allylestrenol interaction with alcohol, hence it is best to consult a doctor.
Pregnancy
safe if prescribedSafe if prescribed.
Breast Feeding
cautionPlease consult your doctor before using Allylestrenol during breastfeeding. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Driving
cautionIt is advised to drive with caution after taking Allylestrenol as it may interfere with driving capabilities. It can make you feel drowsy.
Liver
cautionAllylestrenol should be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.
Kidney
cautionAllylestrenol should be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.
Children
unsafeAllylestrenol is not indicated for use in children. Safety and effectiveness in pediatric patients less than 16 years of age have not been established.
Habit Forming
Diet & Lifestyle Advise
Eat a healthy and balanced diet rich in vegetables, fruits, whole grains for reduced risk of preterm delivery.
Try to include heart-healthy omega 3 fatty acid containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil and coconut oil.
Prefer more whole foods and grains instead of processed ones. Avoid the intake of processed foods, foods high in sugar and fat.
Avoid stress as it can increase the chances of preterm delivery. Try to enjoy and spent time with your loved ones to cope with stress and practice mindfulness techniques.
Do regular physical activity and yoga, it keeps you fit and helps improve blood circulation and regulates oxygen supply, thereby improve the chances of carrying your baby full term.
Quitting smoking is the best strategy to lower the risk of premature delivery.
Keep your weight under control.
Try to avoid alcohol as it can affect your stomach and intestine and limit the absorption of the important nutrients required by your body.
Special Advise
- Allylestrenol is not recommended for use in women less than 16 years of age.
- You should not take Allylestrenol if you have an incomplete abortion.
Patients Concern
Disease/Condition Glossary
A miscarriage is an unexpected loss of pregnancy before the 20th week of pregnancy. Recurrent miscarriage or habitual abortion is two or more repeated pregnancy losses within the first trimester. Miscarriages can happen for many reasons, including hormonal disbalance and diseases like thyroid, diabetes, etc. Symptoms include vaginal spotting, abdominal pain or cramping, fluid or tissue passing from the vagina, and vaginal bleeding.
Preterm labour is also called premature labour when your baby starts getting ready for birth too early in your pregnancy. It can start before 37 completed weeks of pregnancy. Premature labour can be caused by premature rupture of membranes, high blood pressure during pregnancy (pre-eclampsia) and poor diet. Symptoms of preterm labour include leaking fluid or bleeding from the vagina, feeling of pressure in the pelvis, and cramps that feel like menstrual cramps regularly. Few premature babies need special care and also have long-term mental and physical disabilities.
FAQs
Allylestrenol belongs to the category of a synthetic progesterone female hormone called progestin used to prevent premature labour.
Allylestrenol contains Allylestrenol is a progestin (female hormone) that helps in maintaining pregnancy by promoting the attachment of the embryo to lining of the womb and improving blood flow to the placenta. It also relaxes the uterus muscles thereby preventing premature labor and repeated miscarriage.
Yes, Allylestrenol is used to prevent the habitual miscarriage and regular abortion. Your doctor will decide whether you should continue or stop taking Allylestrenol. Do not take medication of your own or self medicate.
No, Allylestrenol is not a contraceptive. It should not be used as an effective form of birth control to prevent pregnancy.
Yes, Allylestrenol may cause weight gain. It can be due to water retention. If you feel that you are gaining a lot of weight while taking Allylestrenol, please consult your doctor.
Allylestrenol should be taken in the dose and duration as prescribed by the doctor.
You should stop using Allylestrenol and tell a doctor before using Allylestrenol if you have uncontrolled high blood pressure (hypertension), unusual vaginal bleeding, liver disease, liver cancer, jaundice during pregnancy, circulation problems or bleeding problems, stroke, blood clot problems, breast cancer, uterus/cervix/vaginal cancer.
The common side effects of Allylestrenol include changes in weight, unwanted hair growth, menstrual disturbances, swelling over the body, fever, headache, and fatigue. Most of the side effects of Allylestrenol do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.
Feeling depressed after taking Allylestrenol is not a common side effect, but it may occur in some individuals due to hormonal changes. Allylestrenol is a synthetic hormone that may cause fluctuations in certain hormone levels, leading to mood changes such as irritability, anxiety, and depression. If you continue to feel depressed, please consult your doctor.
Natural progesterone plays a key role in regulating the menstrual cycle (the monthly process in which a woman's body prepares for pregnancy), preparing the uterus for pregnancy, supporting early pregnancy, preventing lactation during pregnancy, and maintaining a healthy hormonal balance. It also helps reduce the risk of uterine cancer, promotes bone health, and supports mood stability.
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