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ABACAVIR+DOLUTEGRAVIR+LAMIVUDINE

About

ABACAVIR+DOLUTEGRAVIR+LAMIVUDINE belongs to a group of medicines called antiretroviral agents indicated for the treatment of HIV infection. It may lower your chance of developing acquired immunodeficiency syndrome (AIDS) and HIV-related illnesses such as serious infections or cancer.

ABACAVIR+DOLUTEGRAVIR+LAMIVUDINE contains Abacavir, Dolutegravir and Lamivudine. They work by decreasing the amount of HIV in the blood and increasing the number of immune cells that help fight infections in the body. Thereby, ABACAVIR+DOLUTEGRAVIR+LAMIVUDINE helps treat HIV infection.

Sometimes, ABACAVIR+DOLUTEGRAVIR+LAMIVUDINE may cause side effects such as fatigue, headache, and insomnia. These side effects may not require medical attention and resolve gradually over time. However, you are advised to talk to the doctor if the side effects persist or worsen.

Consult the doctor if you are pregnant or planning for pregnancy. Breastfeeding is not recommended due to the potential for HIV transmission. Keep the doctor informed about your health condition and the medicines you are taking to prevent any side effects/interactions.

Uses of ABACAVIR+DOLUTEGRAVIR+LAMIVUDINE

Treatment of HIV infection

Medicinal Benefits

ABACAVIR+DOLUTEGRAVIR+LAMIVUDINE is a combination of three drugs: Abacavir (nucleoside reverse transcriptase inhibitor), Dolutegravir (integrase inhibitor) and Lamivudine (nucleoside reverse transcriptase inhibitor). ABACAVIR+DOLUTEGRAVIR+LAMIVUDINE belongs to a group of antiretroviral medicines indicated for the treatment of HIV infection. ABACAVIR+DOLUTEGRAVIR+LAMIVUDINE works by decreasing the amount of HIV in the blood and increasing the number of immune cells that help fight infections in the body. Thereby, ABACAVIR+DOLUTEGRAVIR+LAMIVUDINE helps treat HIV infection. It may lower your chance of developing acquired immunodeficiency syndrome (AIDS) and HIV-related illnesses such as serious infections or cancer.

Directions for Use

Take ABACAVIR+DOLUTEGRAVIR+LAMIVUDINE with or without food. Swallow the medicine as a whole with water; do not chew or crush it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of ABACAVIR+DOLUTEGRAVIR+LAMIVUDINE

  • Fatigue
  • Headache
  • Insomnia

In-Depth Precautions and Warning

Drug Warnings

Do not take ABACAVIR+DOLUTEGRAVIR+LAMIVUDINE if you are allergic to its components. Inform the doctor if you have/had hepatitis B or C infection, liver, kidney or heart problems, high blood pressure, high cholesterol or diabetes. Consult the doctor if you are pregnant or planning for pregnancy. Avoid breastfeeding while taking ABACAVIR+DOLUTEGRAVIR+LAMIVUDINE. Seek immediate medical attention if you experience symptoms of lactic acidosis (stomach pain with vomiting and nausea; weakness or tiredness; trouble breathing; unusual muscle pain; feeling cold, especially in the arms and legs; dizziness or lightheadedness; or fast/irregular heartbeat), severe liver problems (yellow colouration of skin and eyes, dark coloured urine, light coloured stools, nausea, itching, stomach pain) or signs of infection (fever, cold sores, night sweats, swollen glands, wheezing, cough, weight loss, diarrhoea).

Drug Interactions

Drug-Drug Interactions: Inform the doctor if you take multivitamin/mineral supplements or an antiarrhythmic agent (dofetilide).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interaction: Inform the doctor if you have liver, kidney or heart problems.

Drug-Drug Interactions Checker List:

  • DOFETILIDE
  • Safety Advice

    • Safety Warning

      Alcohol

      consult your doctor

      It is not known whether alcohol interacts with ABACAVIR+DOLUTEGRAVIR+LAMIVUDINE. Please consult your doctor.

    • Safety Warning

      Pregnancy

      caution

      Please consult the doctor if you are pregnant. ABACAVIR+DOLUTEGRAVIR+LAMIVUDINE should be used during pregnancy only if the benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      unsafe

      Breastfeeding is not recommended while on treatment with ABACAVIR+DOLUTEGRAVIR+LAMIVUDINE due to the potential for HIV transmission.

    • Safety Warning

      Driving

      caution

      ABACAVIR+DOLUTEGRAVIR+LAMIVUDINE may cause fatigue. Fatigue affects your ability to drive safely. So, drive or operate machinery only if you are alert.

    • Safety Warning

      Liver

      caution

      ABACAVIR+DOLUTEGRAVIR+LAMIVUDINE is not recommended for patients with moderate or severe liver impairment. Please consult the doctor if you have a liver impairment or any concerns regarding this.

    • Safety Warning

      Kidney

      caution

      Dose adjustment may be needed. Please consult the doctor if you have kidney impairment or any concerns.

    • Safety Warning

      Children

      caution

      Please consult the doctor if you have any concerns regarding the usage of ABACAVIR+DOLUTEGRAVIR+LAMIVUDINE in children.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Practise safe sex by using latex or polyurethane condom; it helps in reducing contact with semen and vaginal fluids.
    • Never share personal items with body fluids or blood on them, such as razor blades or toothbrushes.
    • Do not share or re-use needles, other injection or drug equipment.
    • Eat a healthy and balanced diet. Include fruits and vegetables, and opt for lean protein and whole grains.
    • Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry or seafood.
    • Try to reduce emotional and physical stress by spending time with family or doing whatever makes you happy.

    Special Advise

    If you get a symptom from 2 or more of the following groups while taking ABACAVIR+DOLUTEGRAVIR+LAMIVUDINE, call your healthcare provider right away to find out if you should stop taking ABACAVIR+DOLUTEGRAVIR+LAMIVUDINE.
    Group1: Fever
    Group 2: Rash
    Group 3: Nausea, vomiting, diarrhoea, abdominal/stomach pain
    Group 4: General ill feeling, extreme tiredness or achiness
    Group 5: Shortness of breath, sore throat, cough

    Patients Concern

    Disease/Condition Glossary

    HIV infection: HIV (Human Immunodeficiency Virus) is a virus that attacks the immune system and destroys the white blood cells that help fight infection, making the individual susceptible to other infections or illnesses. People with HIV experience flu-like symptoms such as fever, chills, rash, night sweats, muscle aches, tiredness, and sore throat. These symptoms usually last for days to several weeks. HIV spreads through body fluids such as semen, vaginal fluid, and blood. If left untreated, this condition can lead to AIDS (Acquired Immunodeficiency Syndrome). It is a life-long condition, and there is no definite cure for it. However, it can be controlled by treating it with antiretroviral drugs. 

    FAQs

    ABACAVIR+DOLUTEGRAVIR+LAMIVUDINE is used to treat HIV infection.

    ABACAVIR+DOLUTEGRAVIR+LAMIVUDINE works by decreasing the amount of HIV in the blood and increasing the number of immune cells that help fight infections in the body.

    Do not stop taking ABACAVIR+DOLUTEGRAVIR+LAMIVUDINE without consulting your doctor, as it may reduce the effectiveness of anti-HIV therapy. To treat your condition effectually, continue taking ABACAVIR+DOLUTEGRAVIR+LAMIVUDINE for as long as your doctor prescribes it. Do not hesitate to speak with your doctor if you experience difficulty taking ABACAVIR+DOLUTEGRAVIR+LAMIVUDINE.

    ABACAVIR+DOLUTEGRAVIR+LAMIVUDINE does not cure HIV infection or AIDS. You must stay on continuous therapy to control HIV infection and decrease HIV-related illnesses.

    Antacids or laxatives should be taken 2 hours before and 6 hours after taking ABACAVIR+DOLUTEGRAVIR+LAMIVUDINE. However, consult the doctor if you have any concerns.

    When taken with food, ABACAVIR+DOLUTEGRAVIR+LAMIVUDINE can be taken with iron or calcium supplements. Otherwise, take iron or calcium supplements 2 hours before or 6 hours after taking ABACAVIR+DOLUTEGRAVIR+LAMIVUDINE. However, consult the doctor if you have any concerns.

    Available Medicines for

    ABACAVIR+DOLUTEGRAVIR+LAMIVUDINE

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