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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Problast Capsule is used to treat low blood calcium levels. It increases calcium levels and provides essential nutrients that help maintain bone health. In some cases, this medicine may cause side effects such as constipation or stomach upset, nausea, vomiting, loss of appetite, and headache. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer :

Goddres Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Problast Capsule

Problast Capsule is used to treat low blood calcium levels. Problast Capsule effectively treats various conditions caused by low calcium levels in the body, such as osteoporosis (weak and brittle bones), osteomalacia/rickets (weak bones), hypoparathyroidism (low levels of parathyroid hormone), and latent tetany (a muscle disease with low blood calcium levels). Problast Capsule can also be given to pregnant, nursing, and postmenopausal women to ensure that they are getting enough calcium. Additionally, Problast Capsule is used to treat hyperparathyroidism (overactive parathyroid glands) and metabolic bone disease in people with chronic kidney disease, surgery, or other conditions.

Problast Capsule consists of three medicines: Calcium carbonate (mineral), Calcitriol (Vitamin D3), and  Zinc (mineral). Calcium is a mineral that is used to prevent or treat a calcium deficiency. It provides essential nutrients to maintain bone formation and maintenance. Calcitriol is a synthetic version of Vitamin D3 and treats calcium deficiency with hypoparathyroidism (the parathyroid glands' decreased activity) and metabolic bone diseases in people with chronic kidney failure. It raises Vitamin D levels and thereby increases calcium levels in the blood. This helps in improving the absorption rate of calcium from the intestine. Zinc is a mineral that has an essential role in bone health. Zinc helps to stimulate osteoblastic bone formation and mineralization.

Take Problast Capsule as instructed by your doctor. In some cases, Problast Capsule can cause side effects like constipation or stomach upset, nausea, vomiting, loss of appetite, mood changes, weakness, tiredness, fast or pounding heartbeat, bone/muscle pain, and headache. Most of these side effects of Problast Capsule do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

If you are known to be allergic to Problast Capsule or its inactive components, please inform your doctor. Pregnant or breastfeeding women should consult their doctor before taking Problast Capsule . Higher doses of Vitamin D than the recommended daily dose should be used in pregnant women only when advised by the doctor. Problast Capsule may pass into the breast milk. Hence, breastfeeding mothers need to seek medical advice before starting Problast Capsule . Problast Capsule may contain sugar or sorbitol; hence, caution should be taken to have sugar intolerance, diabetes, and phenylketonuria (increased levels of an amino acid called phenylalanine).

Uses of Problast Capsule

Treatment of Osteoporosis, Postmenopausal osteoporosis Osteomalacia, Rickets, Calcium deficiency and Tetany

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water. Do not crush, chew, or break it.

Medicinal Benefits

Problast Capsule is a combination of three drugs: Calcium carbonate (mineral), Calcitriol (Vitamin D3) and Zinc (mineral) used to treat low blood calcium levels and various associated conditions caused by low calcium levels in the body, such as osteoporosis (weak and brittle bones), osteomalacia/rickets (weak bones), hypoparathyroidism (low levels of parathyroid hormone), and tetany (a muscle disease with low blood calcium levels). Calcium carbonate is a mineral and prevents or treats calcium deficiency. It helps to maintain bone and teeth health. Calcitriol, a synthetic form of Vitamin D3, treats calcium deficiency with hypoparathyroidism (the parathyroid glands' decreased activity) and metabolic bone diseases in people with chronic kidney failure. Zinc is an important mineral in the normal growth and development of the skeletal system. It helps maintain bone density by increasing protein synthesis, which helps protect bone health.

How Problast Capsule Works

Problast Capsule consists of three medicines: Calcium carbonate (mineral), Calcitriol (Vitamin D3), and  Zinc (mineral). Calcium is a mineral that is used to prevent or treat a calcium deficiency. It provides essential nutrients to maintain bone formation and maintenance. Calcitriol is a synthetic version of Vitamin D3 and treats calcium deficiency with hypoparathyroidism (the parathyroid glands' decreased activity) and metabolic bone diseases in people with chronic kidney failure. It raises Vitamin D levels and thereby increases calcium levels in the blood. This helps in improving the absorption rate of calcium from the intestine. Zinc is a mineral that has an essential role in bone health. Zinc helps to stimulate osteoblastic bone formation and mineralization.

Storage

Store in a cool and dry place away from sunlight
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Side Effects of Problast Capsule

  • Nausea
  • Vomiting
  • Headache
  • Stomach pain
  • Constipation
  • Mood changes
  • Tiredness/ weakness
  • Fast or pounding heartbeat

What if I have taken an overdose of Problast Capsule

Take Problast Capsule only as suggested by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

If you are known to be allergic to Problast Capsule or any other medicines, please tell your doctor. If you are pregnant or planning to become pregnant, it is advised to inform your doctor before using Problast Capsule . Higher doses of Vitamin D than the recommended daily dose should be used in pregnant women only when advised by the doctor. Calcitriol in higher doses may harm the fetus. Problast Capsule may pass into the breast milk; hence consult your doctor before taking Problast Capsule if you are a breastfeeding mother. Problast Capsule should be used with caution in children and only if recommended by a doctor. Calcitriol in Problast Capsule can affect growth in children. Inform your doctor if your child is not growing at a normal rate while using Problast Capsule . Problast Capsule is not recommended if you have hypercalcemia (high calcium levels), metastatic calcification (extra deposits of calcium in the body), hypervitaminosis D (high vitamin D levels), and malabsorption syndrome (difficulty absorbing nutrition from food). Inform your doctor before taking Problast Capsule if you have any heart/kidney/liver/blood vessel diseases, kidney stones, sarcoidosis (growth of inflammatory cells in different parts of the body), Crohn's disease (inflammatory bowel disease), Whipple's disease (bacterial infection affecting joints and digestive system), achlorhydria (little or no stomach acid), low levels of bile, and phosphate imbalance. Problast Capsule contains sugar or sorbitol; hence caution should be taken to have an intolerance to sugars, diabetes, and phenylketonuria (increased levels of an amino acid called phenylalanine).

Drug-Drug Interactions

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CalcitriolCarbamazepine
Severe
CalcitriolColecalciferol
Severe

Drug-Drug Interactions

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CalcitriolCarbamazepine
Severe
How does the drug interact with Problast Capsule 10's:
Co-administration of Problast Capsule 10's with Carbamazepine may decrease the effects of Problast Capsule 10's.

How to manage the interaction:
Although there is an interaction, Problast Capsule 10's can be taken with Carbamazepine if prescribed by the doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
CalcitriolColecalciferol
Severe
How does the drug interact with Problast Capsule 10's:
Co-administration of Cholecalciferol and Problast Capsule 10's are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.

How to manage the interaction:
Although there is a possible interaction between colecalciferol and Problast Capsule 10's, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
CalcitriolIsoniazid
Severe
How does the drug interact with Problast Capsule 10's:
Co-administration of Isoniazid with Problast Capsule 10's may decrease the effects of Problast Capsule 10's.

How to manage the interaction:
Although there is an interaction, Problast Capsule 10's can be taken with isoniazid if prescribed by the doctor. Do not stop using any medications without talking to a doctor. Do not discontinue the medication without consulting a doctor.
CalcitriolCalcifediol
Severe
How does the drug interact with Problast Capsule 10's:
Co-administration of Calcifediol and Problast Capsule 10's are forms of vitamin D, and taking too much vitamin D may lead to toxic effects related to increased calcium levels in the blood and urine.

How to manage the interaction:
Taking Calcifediol with Problast Capsule 10's can lead to an interaction, it can be taken if advised by a doctor. Consult the prescriber if you experience symptoms of vitamin D intoxication such as weakness, headache, fatigue, drowsiness, vertigo, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, metallic taste, muscle pain, bone pain, muscle incoordination, and low muscle tone. Do not discontinue the medication without consulting a doctor.
CalcitriolDigitoxin
Severe
How does the drug interact with Problast Capsule 10's:
Co-administration of Problast Capsule 10's with Digitoxin may increase the risk or severity of digitoxin toxicity and irregular heart rhythm.

How to manage the interaction:
Although there is an interaction, Problast Capsule 10's can be taken with Digitoxin if prescribed by the doctor. Consult the prescriber if you experience symptoms that could indicate high blood calcium, such as weakness, fatigue, headache, dizziness, drowsiness, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, a metallic taste in the mouth, bone or muscle pain, incoordination, frequent urination, and weight loss. Also, seek medical attention if you experience symptoms of digitoxin toxicity, such as blurred vision, slow pulse, or irregular heartbeats. Do not discontinue the medication without consulting a doctor.
CalcitriolMetolazone
Severe
How does the drug interact with Problast Capsule 10's:
Co-administration of Metolazone with Problast Capsule 10's can cause blood calcium levels to become too high.

How to manage the interaction:
Although there is an interaction, Problast Capsule 10's can be taken with metolazone if prescribed by the doctor. Consult the doctor if you experience symptoms such as dizziness, drowsiness, weakness, lethargy, headache, nausea, vomiting, or seizures. Do not discontinue the medication without consulting a doctor.
CalcitriolCalcifediol
Severe
How does the drug interact with Problast Capsule 10's:
Co-administration of Calcifediol and Problast Capsule 10's are forms of vitamin D, and taking too much vitamin D may lead to toxic effects related to increased calcium levels in the blood and urine.

How to manage the interaction:
Co-administration of Problast Capsule 10's with Calcifediol can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have any of these symptoms, such as irregular heart rhythm, seizures, it's important to call a doctor right away. Do not discontinue any medications without consulting a doctor.
CalcitriolOrlistat
Severe
How does the drug interact with Problast Capsule 10's:
Co-administration of Orlistat with Problast Capsule 10's may reduce the levels of Problast Capsule 10's which can lead to low treatment outcomes.

How to manage the interaction:
Although there is an interaction, Problast Capsule 10's can be taken with Orlistat when prescribed by the doctor. Do not discontinue any medications without consulting a doctor.
CalcitriolBurosumab
Severe
How does the drug interact with Problast Capsule 10's:
Co-administration of Problast Capsule 10's and Burosumab may cause increases in phosphorus and vitamin D levels in the blood, which may lead to an increased risk of kidney stones.

How to manage the interaction:
There may be a possibility of interaction between Problast Capsule 10's and Burosumab, but it can be taken if prescribed by a doctor. If you have any of these symptoms like kidney stones, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice. Do not discontinue the medication without consulting a doctor.
CalcitriolFosphenytoin
Severe
How does the drug interact with Problast Capsule 10's:
Taking Problast Capsule 10's with Fosphenytoin can reduce the levels and efficacy of Problast Capsule 10's.

How to manage the interaction:
Taking Problast Capsule 10's with Fosphenytoin together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any symptoms of sudden dizziness, weakness, chest pain or pressure, abnormal body movements, uncontrollable eye movements, itching, burning, or tingling sensation, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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CALCIUM CARBONATE-500MG+ZINC-7.5MG+CALCITRIOL-0.25MCGFiber rich foods, Potassium rich foods
Moderate

Drug-Food Interactions

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CALCIUM CARBONATE-500MG+ZINC-7.5MG+CALCITRIOL-0.25MCGFiber rich foods, Potassium rich foods
Moderate
Common Foods to Avoid:
Spinach

How to manage the interaction:
foods high in oxalic acid (spinach) may decrease calcium absorption. Consider taking calcium at least 2 hours before or after eating meals high in oxalic acid or phytic acid.

Diet & Lifestyle Advise

  • Include dairy products like milk, yogurt, cheese, or milk-based custard in your diet.

  • Eat daily a serving of broccoli, cabbage, bok choy, spinach, and other green leafy vegetables.

  • Snack on calcium-rich nuts like Brazil nuts or almonds.

  • Sprinkle sesame seeds over your food, vegetables, and salads. Sesame seeds are high in calcium.

  • Avoid or reduce the intake of caffeine, soft drinks, and alcohol that inhibit calcium absorption.

  • Replace the meat with tofu or tempeh for extra calcium in your food.

Habit Forming

No

Therapeutic Class

MULTIMINERALS

Problast Capsule Substitute

Substitutes safety advice
  • Gemcal Capsule 15's

    22.80per tablet
  • Caldikind Capsule 10's

    9.68per tablet
  • Hhcal-Trol Capsule 15's

    16.50per tablet
  • Bonocal Soft Gelatin Capsule 10's

    by AYUR

    18.72per tablet
  • Gemful Capsule 15's

    18.00per tablet
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Alcohol

Caution

Drinking alcohol can affect calcium absorption; hence it is advised to limit the alcohol intake while using Problast Capsule .

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Pregnancy

Caution

During pregnancy, use higher doses of Problast Capsule than the daily dietary allowance only when advised by the doctor. Calcitriol in higher doses may harm the fetus. Your doctor will weigh the potential risks and benefits before recommending Problast Capsule .

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Breast Feeding

Caution

Consult your doctor before taking Problast Capsule if you are breastfeeding. Problast Capsule can pass into the breast milk. If Problast Capsule is used during breastfeeding, please monitor the mother and the infant's serum calcium levels.

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Driving

Caution

No interaction was found/established.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before taking Problast Capsule . Hepatic impairment/liver disease can alter the metabolic and therapeutic activity of certain Vitamin D forms.

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Kidney

Caution

It is advised to seek doctor advice before starting Problast Capsule if you have kidney diseases like kidney stones or undergoing dialysis. Calcitriol in Problast Capsule increases inorganic phosphate levels in serum; hence caution should be taken in patients undergoing dialysis to maintain adequate phosphorus levels and avoid ectopic calcification (calcium deposition).

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Children

Caution

Problast Capsule should be used with caution in children and only if recommended by a doctor.

FAQs

Problast Capsule is used to treat Osteoporosis, Postmenopausal osteoporosis, Osteomalacia, Rickets, Calcium deficiency and Tetany.
Problast Capsule is a combination of three medicines, namely: Calcium carbonate, Calcitriol and Zinc. Calcitriol helps your body effectively absorb Calcium Carbonate and additionally supports the muscles needed to avoid falls. Calcium and Zinc help build and maintain bones. Collectively, Problast Capsule used to treat osteoporosis (weak and brittle bones), osteomalacia/rickets (weak bones), hypoparathyroidism (low levels of parathyroid hormone), and tetany (a muscle disease with low blood calcium levels).
Problast Capsule is used to increase low levels of calcium in the body. Hence it is not advised to use Problast Capsule during hypercalcemia, since it causes the overdose of calcium leading to kidney stones and other effects.
Problast Capsule can cause kidney stones due to excess calcium deposition when used for a prolonged period. Please consult your doctor before taking Problast Capsule as a daily supplement if you have any kidney problems or a history of kidney stones.
Common side effects of Problast Capsule include constipation, stomach pain, loss of appetite, fast or pounding heartbeat, bone, or muscle pain.
Do not use Problast Capsule if you ate allergic to Problast Capsule or any other ingredients in it. Problast Capsule is not recommended in hypercalcemia (high calcium levels), metastatic calcification (extra deposits of calcium in the body), hypervitaminosis D (high vitamin D levels), and malabsorption syndrome (difficulty absorbing nutrition from food).

Country of origin

INDIA

Manufacturer/Marketer address

Godrej One, 4th Floor, Pirojshanagar, Eastern Express Highway, Vikhroli(East), Mumbai 400079, India
Other Info - PRO1019

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