Calpol 650 mg Tablet belongs to the group of medicines called analgesics (pain killers) and antipyretics (fever-reducing agents) used to reduce fever and treat mild to moderate pain. It is also used to relieve headaches, migraine, toothache, period pain, back pain, muscle pain, and rheumatic pain. Pain and fever are caused by the activation of pain receptors due to the release of certain natural chemicals in the body, like prostaglandin. 

Calpol 650 mg Tablet works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins, reducing pain. Also, Calpol 650 mg Tablet affects an area of the brain that regulates body temperature, known as the hypothalamic heat-regulating centre, reducing fever.

Take Calpol 650 mg Tablet as advised by your physician. Your doctor will recommend how often you need to take Calpol 650 mg Tablet based on your medical condition. In some cases, Calpol 650 mg Tablet may cause side effects such as nausea, stomach pain and dark-coloured urine. Most of these side effects of Calpol 650 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

Avoid taking Calpol 650 mg Tablet if allergic to it. Calpol 650 mg Tablet is not recommended for children below 6 years of age. If you are pregnant or breastfeeding, please consult a physician before using Calpol 650 mg Tablet . Avoid alcohol consumption with Calpol 650 mg Tablet as it may increase the risk of liver damage. If you have an impaired nutritional state caused by anorexia (eating disorder), malnutrition or alcohol abuse or if you are dehydrated, inform your doctor before taking Calpol 650 mg Tablet .

Calpol 650 mg Tablet contains Paracetamol, an analgesic (pain killer) and antipyretic (reduces fever). It inhibits the production of certain chemical messengers in the brain known as prostaglandins, reducing pain. Also, Calpol 650 mg Tablet affects an area of the brain that regulates body temperature known as the hypothalamic heat-regulating centre, reducing fever.

• Nausea
• Stomach pain
• Dark coloured urine

Avoid taking Calpol 650 mg Tablet if allergic to it. Calpol 650 mg Tablet is not recommended for children below 6 years of age. If you are pregnant or breastfeeding, please consult a physician before using Calpol 650 mg Tablet . Avoid alcohol consumption with Calpol 650 mg Tablet as it may increase the risk of liver damage. If you have an impaired nutritional state caused by anorexia (eating disorder), wrong nutrition or alcohol abuse or if you are dehydrated, inform your doctor before taking Calpol 650 mg Tablet . Avoid taking more than recommended doses as it may increase the risk of serious liver damage.

Drug-Drug Interactions: Calpol 650 mg Tablet may interact with blood thinners (warfarin), cholesterol-lowering drugs (cholestyramine), analgesics (aspirin), antibiotics (chloramphenicol, rifampicin), anti-gout medicines (probenecid), antitubercular drug (isoniazid), anticonvulsants (lamotrigine, carbamazepine, phenytoin), and anti-nausea agents (metoclopramide, domperidone). 

Drug-Food Interactions: Calpol 650 mg Tablet may interact with St. John’s wort (herbal medicine to treat depression).  Avoid foods rich in carbohydrates, and pectin including jellies, cabbage, Brussels sprouts and broccoli as Calpol 650 mg Tablet may interact with these foods. Also, avoid intake of alcohol with Calpol 650 mg Tablet as it may increase the risk of liver damage.

Drug-Disease Interactions: If you have kidney or liver disease, hepatitis, Gilbert's syndrome (a liver condition), hemolytic anaemia (abnormal breakdown of red blood cells), G-6-PD deficiency (a hereditary condition resulting in low red blood cell counts), blood poisoning, inform your physician before taking Calpol 650 mg Tablet .

• WARFARIN
• CHOLESTYRAMINE
• ASPIRIN
• METOCLOPRAMIDE
• DOMPERIDONE
• CHLORAMPHENICOL
• RIFAMPICIN
• PROBENECID
• ISONIAZID
• LAMOTRIGINE
• CARBAMAZEPINE
• PHENYTOIN

• Get adequate sleep, as resting the muscles can help in reducing inflammation and swelling.
• Follow heat or cold therapy, and regularly apply a cold or hot compress on the joints for 15-20 minutes.
• Acupuncture, massage and physical therapy may also be helpful.
• Eat foods rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
• Foods containing flavonoids, such as soy, berries, broccoli, grapes, and green tea, help reduce inflammation. 
• Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
• Avoid smoking and alcohol consumption.

If you have a high fever or signs of infection after using Calpol 650 mg Tablet for more than 3 days or if pain persists after using Calpol 650 mg Tablet for more than 5 days, please consult a physician.

Pain: It is a term used to describe any unpleasant feeling or discomfort. It occurs due to nerve damage (in cases of backache, toothache, or muscle pain) or persistent stimulation (in headaches or migraine). Pain may vary from mild to severe, depending on the underlying condition.

Fever: It is an abnormal increase in body temperature due to infection, chemotherapy, or various disease conditions. If the body temperature is 98.6°F, it is normal and if it goes above 100.4°F (38℃), it is called fever or pyrexia. Body temperature is increased in response to infection or varied problems to protect the body. Flu is one of the most common causes of fever.