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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 10, 2024 | 7:17 PM IST
Zosta 20 mg Tablet is used to treat high cholesterol. It contains Simvastatin which works by lowering the levels of bad cholesterol, and triglycerides and raising the levels of good cholesterol. In some cases, this medicine may cause side effects such as headache, stomach pain, constipation, and nausea. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Prescription drug

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Prescription drug
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Composition

SIMVASTATIN-20MG

Manufacturer/Marketer

USV Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Zosta 20 mg Tablet

Zosta 20 mg Tablet is used to lower the levels of increased cholesterol in the body. Additionally, Zosta 20 mg Tablet is also used to lower the risk of heart diseases such as heart attack or stroke. High cholesterol levels might cause a build-up of cholesterol on the artery walls, leading to blockage of blood flow to the heart and other body parts that could cause heart disease, heart attack or stroke.

Zosta 20 mg Tablet contains 'Simvastatin' that works by blocking HMG-CoA reductase, an enzyme necessary for cholesterol production in the body. Zosta 20 mg Tablet helps lower the levels of LDL (bad) cholesterol, and triglycerides and raises the levels of HDL (good) cholesterol. Thereby, Zosta 20 mg Tablet lowers the raised levels of fats, triglycerides and cholesterol, which lowers the risk of heart attack or stroke. 

You are advised to take Zosta 20 mg Tablet as long as your doctor has prescribed it for you, depending on your medical condition. You may experience certain common side effects, such as headache, stomach pain, constipation, and nausea in some cases. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not take Zosta 20 mg Tablet if you are pregnant, think you may be pregnant or if you are trying for pregnancy. Stop taking Zosta 20 mg Tablet and consult a doctor immediately if you become pregnant while taking Zosta 20 mg Tablet . Zosta 20 mg Tablet may cause dizziness, so be cautious while driving. Avoid consuming alcohol with Zosta 20 mg Tablet as it could lead to increased dizziness. Zosta 20 mg Tablet is not recommended for children below 10 years as safety and effectiveness have not been established. Inform your doctor regarding your health condition and the medicines you are taking to rule out any side effects or interactions.

Uses of Zosta 20 mg Tablet

Treatment of Hyperlipidaemia (high cholesterol)

Medicinal Benefits

Zosta 20 mg Tablet contains 'Simvastatin', which belongs to a group of lipid-lowering agents called HMG-CoA reductase inhibitors to lower the increased levels of cholesterol or fat. Zosta 20 mg Tablet works by blocking the HMG-CoA reductase enzyme, which is necessary for cholesterol production in the body. Zosta 20 mg Tablet helps lower the levels of LDL (bad) cholesterol and triglycerides and raises the levels of HDL (good) cholesterol. Thereby, Zosta 20 mg Tablet lowers the blood level of fats and cholesterol and helps prevent a heart attack or stroke. Zosta 20 mg Tablet as an adjunct to dietary measures is used to reduce the risk of having a heart event due to cardiovascular diseases, the incidence of non-fatal heart attack or stroke, the need for revascularisation procedures (restoration of blood flow to the heart), people with diabetes, pre-existing heart disease, and peripheral vascular disease.  

Directions for Use

Swallow Zosta 20 mg Tablet a whole with a glass of water; do not chew, or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Zosta 20 mg Tablet

  • Headache
  • Stomach pain
  • Constipation
  • Nausea

Drug Warnings

Do not take Zosta 20 mg Tablet if you are allergic to any of its contents; if you are taking fusidic acid or have taken it in the past 7 days. Inform your doctor if you are due to have surgery, drink large amounts of alcohol; if you have liver or kidney problems. Do not take Zosta 20 mg Tablet if you are pregnant, breastfeeding, think you may be pregnant or if you are trying for pregnancy. Stop taking Zosta 20 mg Tablet and consult a doctor immediately if you become pregnant while taking Zosta 20 mg Tablet . Zosta 20 mg Tablet may cause dizziness, so be cautious while driving. Avoid consuming alcohol with Zosta 20 mg Tablet as it could lead to increased dizziness. Zosta 20 mg Tablet is not recommended for children below 10 years as safety and effectiveness have not been established.

Drug Interactions

Drug-Drug Interactions: Zosta 20 mg Tablet may interact with antibiotic (fusidic acid, erythromycin, clarithromycin, telithromycin), anti-HIV (indinavir, nelfinavir, ritonavir, saquinavir), anti-fungal (itraconazole, ketoconazole, posaconazole, voriconazole), protease inhibitors (boceprevir, telaprevir), anti-depressant (nefazodone), antilipemic (gemfibrozil), immunosuppressant (cyclosporine), hormone (danazol), cytochrome p450 inhibitor (cobicistat).

Drug-Food Interactions: Avoid consuming grapefruit and grapefruit juice with Zosta 20 mg Tablet . Do not take St. John's wort (herbal supplement to treat depression) with Zosta 20 mg Tablet . 

Drug-Disease Interactions: Inform your doctor if you have liver disease, rhabdomyolysis (muscle breakdown), liver disease, diabetes, or cognitive impairment.

Drug-Drug Interactions Checker List

  • FUSIDIC ACID
  • ERYTHROMYCIN
  • CLARITHROMYCIN
  • TELITHROMYCIN
  • INDINAVIR
  • SAQUINAVIR
  • RITONAVIR
  • NELFINAVIR
  • ITRACONAZOLE
  • KETOCONAZOLE
  • POSACONAZOLE
  • VORICONAZOLE
  • BOCEPREVIR
  • TELAPREVIR
  • NEFAZODONE
  • GEMFIBROZIL
  • CYCLOSPORINE
  • DANAZOL
  • COBICISTAT

Habit Forming

No

Diet & Lifestyle Advise

  • Follow a cholesterol-lowering diet.

  • Exercise regularly. It helps in maintaining proper weight and lowers cholesterol.

  • Limit salt and sugar intake.

  • Avoid smoking and alcohol consumption. 

  • Choose healthy fats and cut down on trans-fat.

  • Include omega-3 fatty acids, fibre-rich food, fruits and vegetables.

  • Get active by doing any physical activity such as swimming, brisk walking or jogging. Take the stairs instead of elevators/lifts.

Special Advise

  • Regular blood tests are advised to determine the effect of Zosta 20 mg Tablet on lipids. 

  • Consult your doctor immediately if you experience muscle pain, weakness, or tenderness, especially if associated with fever or tiredness.

  • Your doctor may recommend blood tests to monitor liver function prior to the start of treatment and during the treatment with Zosta 20 mg Tablet . Inform your doctor if you notice yellowing of skin or eyes, unusually dark urine, and tiredness.

  • Zosta 20 mg Tablet might affect test results for liver function and muscle enzyme (creatin-kinase). Inform the person doing the tests that you are taking Zosta 20 mg Tablet .

  • It is advisable to have complete cholesterol tests (lipid profile test) at least once a year. It will help you to closely monitor your heart health and risk of heart attack and stroke. 

Disease/Condition Glossary

Hyperlipidaemia: Hyperlipidaemia is commonly known as high cholesterol. Cholesterol is a fatty substance that is naturally produced in the liver because every cell uses it. Cholesterol is also found in fatty foods such as cheese, red meat, and eggs. High cholesterol levels might cause a build-up of fat on the arteries' walls, leading to blockage of blood flow to the heart and other body parts that could cause heart disease, heart attack or stroke. Cholesterol is mainly of two types, namely 'bad cholesterol' and 'good cholesterol'. Bad cholesterol comprises low-density lipoprotein (LDL) and triglycerides (TG) which deposit fat in the arteries leading to their blockage. Good cholesterol consists of high-density lipoprotein (HDL), which prevents the deposition of fats. Risk factors of high cholesterol are a high-fat diet, obesity, lack of physical exercise, and smoking. Usually, there are no specific symptoms of raised or high cholesterol levels, so it is advisable to have complete cholesterol tests (lipid profile tests) at least once a year. It will help monitor your heart health and risk of heart attack or stroke. 

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Zosta 20 mg Tablet as it may cause increased dizziness.

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Pregnancy

Unsafe

Zosta 20 mg Tablet belongs to pregnancy category X. Do not take Zosta 20 mg Tablet if you are pregnant, think you may be pregnant or if you are trying for pregnancy. Stop taking Zosta 20 mg Tablet and consult a doctor immediately if you become pregnant while taking Zosta 20 mg Tablet .

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Breast Feeding

Unsafe

It is not known if Zosta 20 mg Tablet passes into breastmilk. Do not take Zosta 20 mg Tablet if you are breastfeeding.

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Driving

Caution

Usually, Zosta 20 mg Tablet does not interfere with your ability to drive or usage of machinery. However, Zosta 20 mg Tablet may cause dizziness in some people. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Zosta 20 mg Tablet is not recommended for children below 10years as the safety and effectiveness have not been established.

Country of origin

India

Manufacturer/Marketer address

Arvind Vithal Gandhi Chowk, BSD Marg, Station Road, Govandi East, Mumbai - 400 088. , India.
Other Info - ZOS0005

Author Details

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FAQs

Zosta 20 mg Tablet is used to lower the levels of increased cholesterol in the body. Additionally, Zosta 20 mg Tablet is also used to lower the risk of heart diseases such as heart attack or stroke.
Zosta 20 mg Tablet works by blocking HMG-CoA reductase, an enzyme necessary for the production of cholesterol in the body. Zosta 20 mg Tablet helps lower the levels of LDL (bad) cholesterol and triglycerides and raises the levels of HDL (good) cholesterol. Thereby, Zosta 20 mg Tablet lowers the blood level of raised fats and cholesterol and helps prevent a heart attack or stroke.
Do not discontinue Zosta 20 mg Tablet without consulting your doctor as it could lead to the rise of cholesterol. To treat your condition effectually, continue taking Zosta 20 mg Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Zosta 20 mg Tablet .
Constipation could be a side-effect of Zosta 20 mg Tablet . Drink plenty of fluids and eat fibre-rich food if you experience constipation. Consult your doctor if you have severe constipation.
Zosta 20 mg Tablet can be taken by diabetes patients if prescribed by the doctor. Your doctor will monitor your condition closely if you have diabetes. Regular monitoring of blood sugar levels is advised.
Zosta 20 mg Tablet should not be taken with antibiotics such as fusidic acid as it could lead to a serious muscle problem called rhabdomyolysis (the breakdown of muscle tissue). Inform the doctor that you are taking Zosta 20 mg Tablet if your doctor has prescribed fusidic acid, the doctor may ask you to temporarily stop taking Zosta 20 mg Tablet to treat your infection. Your doctor will decide when it is safe to restart treatment with Zosta 20 mg Tablet .
Zosta 20 mg Tablet might cause muscle problems, particularly when taken at high doses. In rare conditions, Zosta 20 mg Tablet might cause serious muscle problems such as rhabdomyolysis (muscle tissue breakdown). Consult your doctor immediately if you experience muscle pain, weakness, and tenderness, especially if associated with fever or tiredness.
Zosta 20 mg Tablet may cause side effects such as nausea, headache, stomach pain, and constipation. If these side effects persist or worsen, please consult your doctor.
Swallow Zosta 20 mg Tablet as a whole. Do not crush or break while taking Zosta 20 mg Tablet .
You are recommended to avoid alcohol consumption while taking Zosta 20 mg Tablet as it may increase dizziness and also increase the risk of muscle breakdown. If you have still have any concerns regarding this, please discuss with your doctor.
Take Zosta 20 mg Tablet as advised by your doctor. It is usually taken once a day mostly after dinner. Try to take Zosta 20 mg Tablet at the same time every day for effective results and to remember taking it.
You should take Zosta 20 mg Tablet for as long as it is advised by your doctor. You might need to take it lifelong as cholesterol levels will be maintained only while you are taking Zosta 20 mg Tablet . If you stop Zosta 20 mg Tablet without starting other treatment, your cholesterol levels may increase again. Therefore, do not stop taking it without first consulting your doctor.
You should avoid foods rich in calories like junk food and fried food. It is recommended to eat a low-cholesterol diet and a low-fat. Make sure to follow all the exercise and dietary recommendations made by your dietician or doctor.
Yes, Zosta 20 mg Tablet can make you feel tired. Additionally, Zosta 20 mg Tablet may cause muscle damage which further worsens the tiredness. Therefore, if you feel tired while taking Zosta 20 mg Tablet , consult your doctor.
Yes, Zosta 20 mg Tablet is safe to take in prescribed dose and duration. The patient should follow doctor’s recommendations. Do not exceed the recommended daily dose.

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