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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Zocor 20 mg Tablet is used to treat high cholesterol. It contains Simvastatin which works by lowering the levels of bad cholesterol, and triglycerides and raising the levels of good cholesterol. In some cases, this medicine may cause side effects such as headache, stomach pain, constipation, and nausea. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

SIMVASTATIN-20MG

Manufacturer/Marketer :

Msd Pharmaceutical Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Zocor 20 mg Tablet

Zocor 20 mg Tablet is used to lower the levels of increased cholesterol in the body. Additionally, Zocor 20 mg Tablet is also used to lower the risk of heart diseases such as heart attack or stroke. High cholesterol levels might cause a build-up of cholesterol on the artery walls, leading to blockage of blood flow to the heart and other body parts that could cause heart disease, heart attack or stroke.

Zocor 20 mg Tablet contains 'Simvastatin' that works by blocking HMG-CoA reductase, an enzyme necessary for cholesterol production in the body. Zocor 20 mg Tablet helps lower the levels of LDL (bad) cholesterol, and triglycerides and raises the levels of HDL (good) cholesterol. Thereby, Zocor 20 mg Tablet lowers the raised levels of fats, triglycerides and cholesterol, which lowers the risk of heart attack or stroke. 

You are advised to take Zocor 20 mg Tablet as long as your doctor has prescribed it for you, depending on your medical condition. You may experience certain common side effects, such as headache, stomach pain, constipation, and nausea in some cases. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not take Zocor 20 mg Tablet if you are pregnant, think you may be pregnant or if you are trying for pregnancy. Stop taking Zocor 20 mg Tablet and consult a doctor immediately if you become pregnant while taking Zocor 20 mg Tablet . Zocor 20 mg Tablet may cause dizziness, so be cautious while driving. Avoid consuming alcohol with Zocor 20 mg Tablet as it could lead to increased dizziness. Zocor 20 mg Tablet is not recommended for children below 10 years as safety and effectiveness have not been established. Inform your doctor regarding your health condition and the medicines you are taking to rule out any side effects or interactions.

Uses of Zocor 20 mg Tablet

Treatment of Hyperlipidaemia (high cholesterol)

Directions for Use

Swallow Zocor 20 mg Tablet a whole with a glass of water; do not chew, or break it.

Medicinal Benefits

Zocor 20 mg Tablet contains 'Simvastatin', which belongs to a group of lipid-lowering agents called HMG-CoA reductase inhibitors to lower the increased levels of cholesterol or fat. Zocor 20 mg Tablet works by blocking the HMG-CoA reductase enzyme, which is necessary for cholesterol production in the body. Zocor 20 mg Tablet helps lower the levels of LDL (bad) cholesterol and triglycerides and raises the levels of HDL (good) cholesterol. Thereby, Zocor 20 mg Tablet lowers the blood level of fats and cholesterol and helps prevent a heart attack or stroke. Zocor 20 mg Tablet as an adjunct to dietary measures is used to reduce the risk of having a heart event due to cardiovascular diseases, the incidence of non-fatal heart attack or stroke, the need for revascularisation procedures (restoration of blood flow to the heart), people with diabetes, pre-existing heart disease, and peripheral vascular disease.  

How Zocor 20 mg Tablet Works

Zocor 20 mg Tablet contains 'Simvastatin' that works by blocking HMG-CoA reductase, an enzyme necessary for cholesterol production in the body. Zocor 20 mg Tablet helps lower the levels of LDL (bad) cholesterol, and triglycerides and raises the levels of HDL (good) cholesterol. Thereby, Zocor 20 mg Tablet lowers the raised levels of fats, triglycerides and cholesterol, which lowers the risk of heart attack or stroke.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Zocor 20 mg Tablet

  • Headache
  • Stomach pain
  • Constipation
  • Nausea

What if I have taken an overdose of Zocor 20 mg Tablet

Avoid exceeding the recommended dose as it might cause an overdose. Seek immediate medical attention if you experience any unusual symptoms.

Drug Warnings

Do not take Zocor 20 mg Tablet if you are allergic to any of its contents; if you are taking fusidic acid or have taken it in the past 7 days. Inform your doctor if you are due to have surgery, drink large amounts of alcohol; if you have liver or kidney problems. Do not take Zocor 20 mg Tablet if you are pregnant, breastfeeding, think you may be pregnant or if you are trying for pregnancy. Stop taking Zocor 20 mg Tablet and consult a doctor immediately if you become pregnant while taking Zocor 20 mg Tablet . Zocor 20 mg Tablet may cause dizziness, so be cautious while driving. Avoid consuming alcohol with Zocor 20 mg Tablet as it could lead to increased dizziness. Zocor 20 mg Tablet is not recommended for children below 10 years as safety and effectiveness have not been established.

Drug-Drug Interactions

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SimvastatinRitonavir
Critical
SimvastatinItraconazole
Critical

Drug-Drug Interactions

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SimvastatinRitonavir
Critical
How does the drug interact with Zocor 20 mg Tablet 10's:
Taking Ritonavir and Zocor 20 mg Tablet 10's may increase the risk of side effects.

How to manage the interaction:
Taking Zocor 20 mg Tablet 10's with Ritonavir is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, tiredness, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes, contact a doctor. Do not discontinue any medications without consulting a doctor.
SimvastatinItraconazole
Critical
How does the drug interact with Zocor 20 mg Tablet 10's:
Zocor 20 mg Tablet 10's's blood levels and effects may be greatly increased when combined with itraconazole.

How to manage the interaction:
Zocor 20 mg Tablet 10's and itraconazole may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you have side effects such unexplained pain in the muscles or tenderness, muscle weakness, fever or flu-like symptoms, or dark urine. Without consulting a doctor, never stop taking any medication.
SimvastatinTipranavir
Critical
How does the drug interact with Zocor 20 mg Tablet 10's:
Combining Tipranavir and Zocor 20 mg Tablet 10's can increase the blood levels and effects of Zocor 20 mg Tablet 10's. This can increase the risk of side effects such as liver damage and rhabdomyolysis( involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Tipranavir and Zocor 20 mg Tablet 10's together is not recommended as it can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark-coloured urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
SimvastatinVoriconazole
Critical
How does the drug interact with Zocor 20 mg Tablet 10's:
Taking Voriconazole and Zocor 20 mg Tablet 10's can increase the blood levels and effects of Zocor 20 mg Tablet 10's. This can increase the risk of side effects (liver damage and rhabdomyolysis - involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Voriconazole and Zocor 20 mg Tablet 10's together is not recommended as it can lead to an interaction, but it can be taken if a doctor advises. However, if you experience muscle pain, fever or dark-colored urine, vomiting, and yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
SimvastatinCiclosporin
Critical
How does the drug interact with Zocor 20 mg Tablet 10's:
Combining Ciclosporin and Zocor 20 mg Tablet 10's can increase the blood levels and effects of Zocor 20 mg Tablet 10's. This can increase the risk of side effects such as liver damage and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Ciclosporin and Zocor 20 mg Tablet 10's together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, and yellowing of the skin or eyes, contact the doctor immediately. Do not discontinue any medications without consulting your doctor.
SimvastatinNefazodone
Critical
How does the drug interact with Zocor 20 mg Tablet 10's:
Combining Nefazodone and Zocor 20 mg Tablet 10's can increase the blood levels and effects of Zocor 20 mg Tablet 10's. This can increase the risk of side effects such as liver damage and rhabdomyolysis( involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Nefazodone and Zocor 20 mg Tablet 10's together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
SimvastatinIndinavir
Critical
How does the drug interact with Zocor 20 mg Tablet 10's:
Combining Indinavir and Zocor 20 mg Tablet 10's can increase the blood levels and effects of Zocor 20 mg Tablet 10's. This can increase the risk of side effects such as liver damage and rhabdomyolysis( involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Indinavir and Zocor 20 mg Tablet 10's together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
SimvastatinTelithromycin
Critical
How does the drug interact with Zocor 20 mg Tablet 10's:
Combining Telithromycin and Zocor 20 mg Tablet 10's can increase the blood levels and effects of Zocor 20 mg Tablet 10's. This can increase the risk of side effects such as liver damage and rhabdomyolysis( involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Telithromycin and Zocor 20 mg Tablet 10's together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
SimvastatinMifepristone
Critical
How does the drug interact with Zocor 20 mg Tablet 10's:
Combining Mifepristone with Zocor 20 mg Tablet 10's can increase the blood levels of Zocor 20 mg Tablet 10's, which may increase the risk of side effects.

How to manage the interaction:
Taking Zocor 20 mg Tablet 10's with Mifepristone is not recommended, but can be taken if prescribed by the doctor. If you experience any symptoms, contact the doctor immediately. Do not discontinue any medications without consulting a doctor.
SimvastatinClarithromycin
Critical
How does the drug interact with Zocor 20 mg Tablet 10's:
Co-administration of Clarithromycin and Zocor 20 mg Tablet 10's can increase the blood levels and effects of Zocor 20 mg Tablet 10's. This can increase the risk of side effects such as liver damage and rhabdomyolysis(which involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Clarithromycin and Zocor 20 mg Tablet 10's together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

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SIMVASTATIN-20MGGrapefruit and Grapefruit Juice, Vitamin-K rich foods
Severe

Drug-Food Interactions

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SIMVASTATIN-20MGGrapefruit and Grapefruit Juice, Vitamin-K rich foods
Severe
Common Foods to Avoid:
Grapefruit Juice, Grapefruit, Green Tea

How to manage the interaction:
Taking grapefruit or grape juice and green tea or green tea extracts can increase the blood levels of Zocor 20 mg Tablet 10's and can increase the risk of liver damage and rhabdomyolysis (breakdown of skeletal muscle tissue). Taking grapefruit or grape juice and green tea or green tea extracts can lead to an interaction. However, if you experience any symptoms like muscle pain, tenderness, or weakness during treatment, fever or dark-colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Avoid taking grapefruit or grape juice and green tea or green tea extracts.

Diet & Lifestyle Advise

  • Follow a cholesterol-lowering diet.

  • Exercise regularly. It helps in maintaining proper weight and lowers cholesterol.

  • Limit salt and sugar intake.

  • Avoid smoking and alcohol consumption. 

  • Choose healthy fats and cut down on trans-fat.

  • Include omega-3 fatty acids, fibre-rich food, fruits and vegetables.

  • Get active by doing any physical activity such as swimming, brisk walking or jogging. Take the stairs instead of elevators/lifts.

Habit Forming

No

Therapeutic Class

ANTILIPEMICS

Zocor 20 mg Tablet Substitute

Substitutes safety advice
  • Simvotin 20 Tablet 10's

    27.99per tablet
  • Simwel-20 Tablet 10's

    19.80per tablet
  • SIMLO 20MG TABLET

    6.74per tablet
  • SIMVAS 20MG TABLET

    3.87per tablet
  • Simcard 20 mg Tablet 10's

    15.59per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Zocor 20 mg Tablet as it may cause increased dizziness.

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Pregnancy

Unsafe

Zocor 20 mg Tablet belongs to pregnancy category X. Do not take Zocor 20 mg Tablet if you are pregnant, think you may be pregnant or if you are trying for pregnancy. Stop taking Zocor 20 mg Tablet and consult a doctor immediately if you become pregnant while taking Zocor 20 mg Tablet .

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Breast Feeding

Unsafe

It is not known if Zocor 20 mg Tablet passes into breastmilk. Do not take Zocor 20 mg Tablet if you are breastfeeding.

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Driving

Caution

Usually, Zocor 20 mg Tablet does not interfere with your ability to drive or usage of machinery. However, Zocor 20 mg Tablet may cause dizziness in some people. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Zocor 20 mg Tablet is not recommended for children below 10years as the safety and effectiveness have not been established.

FAQs

Zocor 20 mg Tablet is used to lower the levels of increased cholesterol in the body. Additionally, Zocor 20 mg Tablet is also used to lower the risk of heart diseases such as heart attack or stroke.
Zocor 20 mg Tablet works by blocking HMG-CoA reductase, an enzyme necessary for the production of cholesterol in the body. Zocor 20 mg Tablet helps lower the levels of LDL (bad) cholesterol and triglycerides and raises the levels of HDL (good) cholesterol. Thereby, Zocor 20 mg Tablet lowers the blood level of raised fats and cholesterol and helps prevent a heart attack or stroke.
Do not discontinue Zocor 20 mg Tablet without consulting your doctor as it could lead to the rise of cholesterol. To treat your condition effectually, continue taking Zocor 20 mg Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Zocor 20 mg Tablet .
Constipation could be a side-effect of Zocor 20 mg Tablet . Drink plenty of fluids and eat fibre-rich food if you experience constipation. Consult your doctor if you have severe constipation.
Zocor 20 mg Tablet can be taken by diabetes patients if prescribed by the doctor. Your doctor will monitor your condition closely if you have diabetes. Regular monitoring of blood sugar levels is advised.
Zocor 20 mg Tablet should not be taken with antibiotics such as fusidic acid as it could lead to a serious muscle problem called rhabdomyolysis (the breakdown of muscle tissue). Inform the doctor that you are taking Zocor 20 mg Tablet if your doctor has prescribed fusidic acid, the doctor may ask you to temporarily stop taking Zocor 20 mg Tablet to treat your infection. Your doctor will decide when it is safe to restart treatment with Zocor 20 mg Tablet .
Zocor 20 mg Tablet might cause muscle problems, particularly when taken at high doses. In rare conditions, Zocor 20 mg Tablet might cause serious muscle problems such as rhabdomyolysis (muscle tissue breakdown). Consult your doctor immediately if you experience muscle pain, weakness, and tenderness, especially if associated with fever or tiredness.
Zocor 20 mg Tablet may cause side effects such as nausea, headache, stomach pain, and constipation. If these side effects persist or worsen, please consult your doctor.
Swallow Zocor 20 mg Tablet as a whole. Do not crush or break while taking Zocor 20 mg Tablet .
You are recommended to avoid alcohol consumption while taking Zocor 20 mg Tablet as it may increase dizziness and also increase the risk of muscle breakdown. If you have still have any concerns regarding this, please discuss with your doctor.
Take Zocor 20 mg Tablet as advised by your doctor. It is usually taken once a day mostly after dinner. Try to take Zocor 20 mg Tablet at the same time every day for effective results and to remember taking it.
You should take Zocor 20 mg Tablet for as long as it is advised by your doctor. You might need to take it lifelong as cholesterol levels will be maintained only while you are taking Zocor 20 mg Tablet . If you stop Zocor 20 mg Tablet without starting other treatment, your cholesterol levels may increase again. Therefore, do not stop taking it without first consulting your doctor.
You should avoid foods rich in calories like junk food and fried food. It is recommended to eat a low-cholesterol diet and a low-fat. Make sure to follow all the exercise and dietary recommendations made by your dietician or doctor.
Yes, Zocor 20 mg Tablet can make you feel tired. Additionally, Zocor 20 mg Tablet may cause muscle damage which further worsens the tiredness. Therefore, if you feel tired while taking Zocor 20 mg Tablet , consult your doctor.
Yes, Zocor 20 mg Tablet is safe to take in prescribed dose and duration. The patient should follow doctor’s recommendations. Do not exceed the recommended daily dose.

Country of origin

India

Manufacturer/Marketer address

Platina, 8th Floor, C.59, G Block, Bandra Kurla Complex, Bandra (East) , Mumbai - 400098,
Other Info - ZOC0031

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