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Written By , M Pharmacy
Reviewed By , MPharma., PhD
Last Updated Jan 1, 2025 | 2:48 PM IST
Zione DS L Tablet is used to treat high blood pressure. It contains Losartan and Chlorthalidone which work by widening the blood vessels, improving blood flow, and preventing fluid retention. In some cases, this medicine may cause side effects such as nausea, taste changes, stomach upset, diarrhoea, headache, weakness, dizziness and decreased blood pressure. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Prescription drug

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Manufacturer/Marketer :

Torrent Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Apr-26

About Zione DS L Tablet

Zione DS L Tablet belongs to the class of ‘anti-hypertensive drugs’ primarily used to treat high blood pressure (hypertension). Hypertension is a medical condition in which blood pressure is elevated persistently in the arteries. It is considered an essential risk factor for cardiovascular diseases like heart attack, stroke, myocardial infarction etc. 

Zione DS L Tablet consists of two medicines, namely: Losartan and Chlorthalidone. Losartan belongs to a group of angiotensin II receptor antagonists which narrows constricted blood vessels and widens it. Thus, it lowers elevated blood pressure and increases blood flow by preventing blood vessel narrowing. Chlorthalidone belongs to thiazide diuretics (water pill) which inhibits sodium and chloride reabsorption from absorbing excess salts that cause fluid retention or build-up. Thus, it also relaxes the blood vessels to improve blood circulation and lowers raised blood pressure.  

Your doctor will decide the dosage of Zione DS L Tablet based on your medical condition. In some cases, Zione DS L Tablet can cause side effects like nausea, taste changes, stomach upset, diarrhoea, headache, weakness, dizziness and decreased blood pressure. Most of these side effects of Zione DS L Tablet do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

If you are known to be allergic to Zione DS L Tablet or any other medicines, please inform your doctor. Before taking Zione DS L Tablet , let your doctor know if you have any kidney, liver problems or severe dehydration. Pregnant and breastfeeding women should consult their doctor before taking Zione DS L Tablet . Please do not stop taking Zione DS L Tablet on your own, leading to the recurrence of symptoms or worsening the condition. Do not consume alcohol with Zione DS L Tablet as it may increase the risk of low blood pressure. Avoid driving or operating machinery if you experience dizziness.

Uses of Zione DS L Tablet

Treatment of High blood pressure (hypertension)

Medicinal Benefits

Zione DS L Tablet is an anti-hypertensive medication that treats high blood pressure (hypertension). It consists of Losartan and Chlorthalidone. Losartan is an angiotensin II receptor antagonist. It lowers the blood pressure and increases the blood flow by inhibiting angiotensin (a hormone that constricts blood vessels). Losartan is also used to treat stroke and slow down kidney damage in people with type 2 diabetes. It also increases urinary flow rate and aids in the excretion of electrolytes like chloride, magnesium, calcium and phosphate and by-products like uric acid. Chlorthalidone is a thiazide diuretic (water pill) with antihypertensive activity. It inhibits sodium and chloride reabsorption from absorbing excess salts that cause fluid retention or build-up. Chlorthalidone lowers blood pressure by decreasing the amount of blood the heart pumps (cardiac output) and reducing plasma and extracellular fluid volume (body fluids outside the cells). 

Side Effects of Zione DS L Tablet

  • Nausea
  • Taste changes
  • Stomach upset
  • Diarrhoea
  • Headache
  • Weakness
  • Dizziness
  • Decreased blood pressure (hypotension)  

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Complete the course strictly as suggested by the doctor, even if you feel better, to avoid disease recurrence. Let your doctor know if you have any history of heart, kidney or liver diseases, severe dehydration, high potassium levels (hyperkalaemia), low potassium levels (hypokalaemia), diabetes, high cholesterol levels, electrolyte imbalance, asthma, lupus (an autoimmune disease), gout and thyroid disorders before starting Zione DS L Tablet . Pregnant women should consult their doctor before taking Zione DS L Tablet . Chlorthalidone in Zione DS L Tablet passes into the breast milk during breastfeeding. Hence, it is advised to inform your doctor before using Zione DS L Tablet if you are a nursing mother. Avoid operating any machines or doing any work that needs mental alertness if you feel dizzy after taking Zione DS L Tablet . It is advised to avoid alcohol consumption while using Zione DS L Tablet to prevent dizziness and risk of low blood pressure. Zione DS L Tablet is not recommended for use in patients younger than 18 years of age. 

Therapeutic Class

ANTI- HYPERTENSIVES

Drug-Drug Interactions

verifiedApollotooltip
chlorthalidoneCisapride
Critical
LosartanPerindopril
Severe

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Keep your weight under control with body mass index (BMI) between 19.5 and 24.9.
  • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help you to lower your raised blood pressure by about 5 mm of Hg.
  • Limit sodium chloride intake (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.
  • If you are taking alcohol, use only one serving for women and two servings for men.
  • Quit smoking to lower the risk of heart diseases. 
  • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress.
  • Monitor your blood pressure daily, and if you notice any fluctuations frequently, please contact your doctor immediately.
  • Try including heart-healthy omega 3 fatty acid-containing foods in your daily diet. You can also use low-fat cooking oils like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

Habit Forming

No

How Zione DS L Tablet Works

Zione DS L Tablet consists of two medicines, namely: Losartan and Chlorthalidone. Losartan belongs to a group of angiotensin II receptor antagonists which narrows constricted blood vessels and widens it. Thus, it lowers elevated blood pressure and increases blood flow by preventing blood vessel narrowing. Chlorthalidone belongs to thiazide diuretics (water pill) which inhibits sodium and chloride reabsorption from absorbing excess salts that cause fluid retention or build-up. Thus, it also relaxes the blood vessels to improve blood circulation and lowers raised blood pressure.

What if I have taken an overdose of Zione DS L Tablet

Avoid exceeding the recommended dose as it might cause an overdose. Seek immediate medical attention if you experience any unusual symptoms.
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Alcohol

Unsafe

It is unsafe to consume alcohol, since alcohol consumption with Zione DS L Tablet may increase the risk of low blood pressure and cause adverse effects, such as dizziness, fainting, light-headedness, or headache.

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Pregnancy

Unsafe

Zione DS L Tablet is not recommended during pregnancy since it may affect and harm the baby. Consult your doctor before taking Zione DS L Tablet if you plan to become pregnant or already pregnant. Your doctor will weigh the potential risks and benefits before prescribing Zione DS L Tablet .

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Breast Feeding

Caution

Chlorthalidone in Zione DS L Tablet is not recommended during breastfeeding. Please consult your doctor before taking Zione DS L Tablet if you are breastfeeding.

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Driving

Caution

Zione DS L Tablet may cause side effects like dizziness or tiredness, which can affect your ability to concentrate and drive. Hence, it is recommended not to drive or operate machinery until you are mentally alert.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before taking Zione DS L Tablet . The dosage will be initiated in lower doses and will be further adjusted in patients with liver diseases.

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Kidney

Caution

Zione DS L Tablet consists of Losartan drug, which may affect the kidney functioning. Hence it is advised to seek doctor advice before starting Zione DS L Tablet if you have kidney problems.

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Children

Unsafe

Safety and efficacy of Zione DS L Tablet have not been established in patients younger than 18 years.

Country of origin

India

Manufacturer/Marketer address

Unichem Laboratories Ltd., Unichem Bhavan, Prabhat Estate, Off S.V.Road, Jogeshwari (West), Mumbai ? 400 102.
Other Info - ZIO0019

Author Details

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FAQs

Zione DS L Tablet is used to treat high blood pressure (hypertension).
Zione DS L Tablet works by relaxing and widening the blood vessels to make the heart pump blood easily throughout the body and also prevents fluid retention due to excess salts build-up, thereby lowering the raised blood pressure.
Zione DS L Tablet can make you feel dizzy. Dizziness usually occurs when you suddenly stand up from a lying or sitting position. Try rising slowly when you change your posture to relieve dizziness. If the side effect persists longer, please seek medical help.
Zione DS L Tablet can cause high levels of potassium in the blood leading to hyperkalaemia. Hence it is not recommended to use potassium supplements along with Zione DS L Tablet . However, consult your doctor if you are already taking other medicines before starting Zione DS L Tablet .
Chlorthalidone in Zione DS L Tablet may affect blood sugar levels in people with diabetes. Hence, it is advised to monitor your sugar levels while taking Zione DS L Tablet regularly. Your doctor may adjust the dose accordingly. Please seek medical advice for more information before starting Zione DS L Tablet .
Even though your blood pressure becomes normal after using Zione DS L Tablet , it may switch back to high ranges if you stop using it. Your doctor may change the dosing schedule based on your blood pressure range.
Zione DS L Tablet can cause dehydration. It is advised to drink plenty of fluids and avoid hard exercises and sports to prevent dehydration. If you experience extreme thirst and dry mouth for a longer period, please seek medical advice.

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