Zepenta Dsr Tablet is used to treat nausea (feeling sick) and vomiting (being sick) in adults and adolescents 12 years or older. Besides this, it also helps in the treatment of indigestion. Nausea and vomiting are not diseases but are symptoms of many conditions like infections, motion sickness, an early stage of pregnancy, and gastroparesis (slow stomach emptying).

Zepenta Dsr Tablet contains domperidone, which prevents nausea and vomiting symptoms by blocking certain receptors (like dopamine and serotonin) that stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. It also acts as a prokinetic agent that increases the upper gastrointestinal tract's motility and helps decrease stomach emptying time.

Take Zepenta Dsr Tablet as prescribed by your doctor. Symptoms of nausea and vomiting may usually resolve within 3-4 days after taking Zepenta Dsr Tablet. However, if it does not resolve even after this, stop taking this medicine and contact the doctor. Do not take Zepenta Dsr Tablet for longer than seven days. The most common side effect of Zepenta Dsr Tablet is dry mouth. This side effect is temporary and may resolve after some time; however, if this side persists, contact the doctor.

Do not consume Zepenta Dsr Tablet if you are hypersensitive to any components present in Zepenta Dsr Tablet. Before taking the Zepenta Dsr Tablet, inform your doctor if you suffer from liver or kidney problems. Prolonged intake of Zepenta Dsr Tablet may be associated with an increased risk of heart rhythm disorder (arrhythmia) and cardiac arrest (heart attack). This risk may be more likely in the elderly (those over 60 years old) or those taking doses higher than 30 mg daily. Zepenta Dsr Tablet is not usually recommended in pregnancy and breastfeeding. But in some cases, domperidone is used to increase milk supply. However, it should be used only during breastfeeding if your physician considers this necessary. Ask your doctor for advice before taking this medicine. Adolescents (children from 12-18 years of age) who weigh less than 35 kg should not be given the Zepenta Dsr Tablet.

Zepenta Dsr Tablet contains domperidone, a dopamine antagonist that helps by blocking certain vomiting-inducing receptors in the brain. Zepenta Dsr Tablet also acts as a prokinetic agent that increases the upper gastrointestinal tract's motility and decreases gastric emptying time. Domperidone is occasionally used to boost milk production. If you're experiencing difficulty nursing, your doctor may prescribe it if nothing else has helped.

• Dry mouth
• Headache

Do not consume Zepenta Dsr Tablet if you are allergic to any components present in Zepenta Dsr Tablet. Before taking the Zepenta Dsr Tablet, contact your doctor if you suffer from liver or kidney problems (kidney function impairment or failure). Prolonged intake of Zepenta Dsr Tablet may be associated with an increased risk of heart rhythm disorder (arrhythmia) and cardiac arrest (heart attack). This risk may be more likely in the elderly (those over 60 years old) or taking doses higher than 30 mg daily. Tell your doctor if you are using anti-fungal medicines and/or if you have heart problems or AIDS/HIV. If you experience heart rhythm disorders like palpitations, trouble breathing, or loss of consciousness after taking the Zepenta Dsr Tablet, immediately contact your doctor. Domperidone is not usually recommended in pregnancy and breastfeeding. But in some cases, domperidone is used to increase milk supply. However, it should be used only during breastfeeding if your physician considers this necessary. Ask your doctor for advice before taking this medicine. Adolescents (children from 12-18 years of age) who weigh less than 35 kg should not be given the Zepenta Dsr Tablet.

Drug-Drug Interactions: Zepenta Dsr Tablet may interact with medicines used to treat heart problems or high blood pressure (e.g. amiodarone, dronedarone, quinidine, disopyramide, dofetilide, sotalol, diltiazem, verapamil), depression (e.g. citalopram, escitalopram),  anti-cancer agents (e.g. toremifene, vandetanib, vincamine), bacterial infections (e.g. specifically erythromycin, clarithromycin, telithromycin, moxifloxacin, pentamidine), gastrointestinal disorders (e.g. cisapride, dolasetron, prucalopride), antimalarial (e.g. halofantrine), neuro related medicines (e.g. haloperidol, pimozide, sertindole), antifungal (e.g. ketoconazole, fluconazole, voriconazole), gastrointestinal drugs (e.g. cisapride, dolasetron, prucalopride) and anti HIV drugs.

Drug-Food Interactions: Zepenta Dsr Tablet may interact with grapefruit juice, alcohol, and tobacco. This may affect the efficacy of Zepenta Dsr Tablet. So, a Zepenta Dsr Tablet should not be taken along with them.

Drug-Disease Interactions: Caution should be exercised while using Zepenta Dsr Tablet in patients with heart, kidney, liver disease, brain tumours, history of gastrointestinal bleeding, or any problem involving the bowels.

• AMIODARONE
• MOXIFLOXACIN
• ERYTHROMYCIN
• DILTIAZEM
• SOTALOL
• ESCITALOPRAM
• VERAPAMIL

• Eat a healthy low-fat diet, especially in small portions, as it will be easy to digest. Avoid eating over-sweet food and include more salty food, especially if you have been vomiting.

• Also, if you like vomiting at a specific time, avoid eating your favourite food at that particular time, as your taste for that food may get turned off. 

• Include more cool beverages in your food like clear soups, flavoured gelatin, and carbonated beverages. And also, when you drink with a stray, sip slowly to avoid swallowing air that may lead to gas or acidity.

• Drink after or any other liquid at least 30 minutes after eating food. After eating food, lie down for at least after 2 hours.

• If the smell of food makes you feel sick (vomit), do not cook food as it may worsen your condition. Let someone else cook food or use prepared food from the freezer.

• Avoid caffeine-containing beverages (coffee, tea), spicy/deep-fried/processed foods, carbonated drinks, and acidic foods like citrus fruits/vegetables (tomatoes).

Nausea is a feeling of stomach uneasiness that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth. In short, nausea and vomiting are not diseases but are symptoms of many conditions like infections, motion sickness, an early stage of pregnancy, and gastroparesis (slow stomach emptying). A receptor in our brain known as the chemoreceptor zone (CTZ) controls vomiting.