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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 10, 2024 | 7:20 PM IST
Preza Dsr Tablet is used to treat nausea and vomiting in adults and adolescents 12 years or older. Besides this, it also helps in the treatment of indigestion. It contains Domperidone, which prevents nausea and vomiting symptoms by blocking certain receptors (like dopamine and serotonin) that stimulate the vomiting centre in the brain. It also increases the upper gastrointestinal tract's motility and helps decrease stomach emptying time. The most common side effect of this medicine is dry mouth. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Prescription drug

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Composition

DOMPERIDONE-30MG

Manufacturer/Marketer

Abbott India Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Preza Dsr Tablet

Preza Dsr Tablet is used to treat nausea (feeling sick) and vomiting (being sick) in adults and adolescents 12 years or older. Besides this, it also helps in the treatment of indigestion. Nausea and vomiting are not diseases but are symptoms of many conditions like infections, motion sickness, an early stage of pregnancy, and gastroparesis (slow stomach emptying).

Preza Dsr Tablet contains domperidone, which prevents nausea and vomiting symptoms by blocking certain receptors (like dopamine and serotonin) that stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. It also acts as a prokinetic agent that increases the upper gastrointestinal tract's motility and helps decrease stomach emptying time.

Take Preza Dsr Tablet as prescribed by your doctor. Symptoms of nausea and vomiting may usually resolve within 3-4 days after taking Preza Dsr Tablet. However, if it does not resolve even after this, stop taking this medicine and contact the doctor. Do not take Preza Dsr Tablet for longer than seven days. The most common side effect of Preza Dsr Tablet is dry mouth. This side effect is temporary and may resolve after some time; however, if this side persists, contact the doctor.

Do not consume Preza Dsr Tablet if you are hypersensitive to any components present in Preza Dsr Tablet. Before taking the Preza Dsr Tablet, inform your doctor if you suffer from liver or kidney problems. Prolonged intake of Preza Dsr Tablet may be associated with an increased risk of heart rhythm disorder (arrhythmia) and cardiac arrest (heart attack). This risk may be more likely in the elderly (those over 60 years old) or those taking doses higher than 30 mg daily. Preza Dsr Tablet is not usually recommended in pregnancy and breastfeeding. But in some cases, domperidone is used to increase milk supply. However, it should be used only during breastfeeding if your physician considers this necessary. Ask your doctor for advice before taking this medicine. Adolescents (children from 12-18 years of age) who weigh less than 35 kg should not be given the Preza Dsr Tablet.

Uses of Preza Dsr Tablet

Treatment of Nausea, Vomiting.

Medicinal Benefits

Preza Dsr Tablet contains domperidone, a dopamine antagonist that helps by blocking certain vomiting-inducing receptors in the brain. Preza Dsr Tablet also acts as a prokinetic agent that increases the upper gastrointestinal tract's motility and decreases gastric emptying time. Domperidone is occasionally used to boost milk production. If you're experiencing difficulty nursing, your doctor may prescribe it if nothing else has helped.

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.Dispersible Tablet: Check the label for directions before use. Disperse the tablet in the prescribed amount of water and swallow the contents. Do not crush, chew or swallow as a whole.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Preza Dsr Tablet

  • Dry mouth
  • Headache

Drug Warnings

Do not consume Preza Dsr Tablet if you are allergic to any components present in Preza Dsr Tablet. Before taking the Preza Dsr Tablet, contact your doctor if you suffer from liver or kidney problems (kidney function impairment or failure). Prolonged intake of Preza Dsr Tablet may be associated with an increased risk of heart rhythm disorder (arrhythmia) and cardiac arrest (heart attack). This risk may be more likely in the elderly (those over 60 years old) or taking doses higher than 30 mg daily. Tell your doctor if you are using anti-fungal medicines and/or if you have heart problems or AIDS/HIV. If you experience heart rhythm disorders like palpitations, trouble breathing, or loss of consciousness after taking the Preza Dsr Tablet, immediately contact your doctor. Domperidone is not usually recommended in pregnancy and breastfeeding. But in some cases, domperidone is used to increase milk supply. However, it should be used only during breastfeeding if your physician considers this necessary. Ask your doctor for advice before taking this medicine. Adolescents (children from 12-18 years of age) who weigh less than 35 kg should not be given the Preza Dsr Tablet.

Drug Interactions

Drug-Drug Interactions: Preza Dsr Tablet may interact with medicines used to treat heart problems or high blood pressure (e.g. amiodarone, dronedarone, quinidine, disopyramide, dofetilide, sotalol, diltiazem, verapamil), depression (e.g. citalopram, escitalopram),  anti-cancer agents (e.g. toremifene, vandetanib, vincamine), bacterial infections (e.g. specifically erythromycin, clarithromycin, telithromycin, moxifloxacin, pentamidine), gastrointestinal disorders (e.g. cisapride, dolasetron, prucalopride), antimalarial (e.g. halofantrine), neuro related medicines (e.g. haloperidol, pimozide, sertindole), antifungal (e.g. ketoconazole, fluconazole, voriconazole), gastrointestinal drugs (e.g. cisapride, dolasetron, prucalopride) and anti HIV drugs.

Drug-Food Interactions: Preza Dsr Tablet may interact with grapefruit juice, alcohol, and tobacco. This may affect the efficacy of Preza Dsr Tablet. So, a Preza Dsr Tablet should not be taken along with them.

Drug-Disease Interactions: Caution should be exercised while using Preza Dsr Tablet in patients with heart, kidney, liver disease, brain tumours, history of gastrointestinal bleeding, or any problem involving the bowels.

Drug-Drug Interactions Checker List

  • AMIODARONE
  • MOXIFLOXACIN
  • ERYTHROMYCIN
  • DILTIAZEM
  • SOTALOL
  • ESCITALOPRAM
  • VERAPAMIL

Habit Forming

No

Diet & Lifestyle Advise

  • Eat a healthy low-fat diet, especially in small portions, as it will be easy to digest. Avoid eating over-sweet food and include more salty food, especially if you have been vomiting.

  • Also, if you like vomiting at a specific time, avoid eating your favourite food at that particular time, as your taste for that food may get turned off. 

  • Include more cool beverages in your food like clear soups, flavoured gelatin, and carbonated beverages. And also, when you drink with a stray, sip slowly to avoid swallowing air that may lead to gas or acidity.

  • Drink after or any other liquid at least 30 minutes after eating food. After eating food, lie down for at least after 2 hours.

  • If the smell of food makes you feel sick (vomit), do not cook food as it may worsen your condition. Let someone else cook food or use prepared food from the freezer.

  • Avoid caffeine-containing beverages (coffee, tea), spicy/deep-fried/processed foods, carbonated drinks, and acidic foods like citrus fruits/vegetables (tomatoes).

Disease/Condition Glossary

Nausea is a feeling of stomach uneasiness that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth. In short, nausea and vomiting are not diseases but are symptoms of many conditions like infections, motion sickness, an early stage of pregnancy, and gastroparesis (slow stomach emptying). A receptor in our brain known as the chemoreceptor zone (CTZ) controls vomiting.

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Alcohol

Unsafe

Drinking alcohol with Preza Dsr Tablet may cause sleepiness, or an irregular heartbeat.

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Pregnancy

Unsafe

Preza Dsr Tablet is not usually recommended in pregnancy.

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Breast Feeding

Caution

Preza Dsr Tablet is not usually recommended when breastfeeding. But in some cases, domperidone is used to increase milk supply. However, it should be used only during breastfeeding if your physician considers this necessary. Ask your doctor for advice before taking this medicine.

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Driving

Safe

Preza Dsr Tablet has no effect on your ability to drive or operate machinery.

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Liver

Caution

Preza Dsr Tablet should be taken with precaution in patients with liver disease. Your doctor will weigh the benefits and potential risks before prescribing them. Please consult your doctor.

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Kidney

Caution

Preza Dsr Tablet should be taken with caution in patients with kidney problems. Your doctor will adjust your dose depending upon the condition of your disease.

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Children

Caution

Preza Dsr Tablet should not be given to adolescents younger than 12 years of age or are less than 35 kg in weight.

Country of origin

India

Manufacturer/Marketer address

16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India
Other Info - PRE0384

Author Details

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FAQs

Preza Dsr Tablet is used to treat nausea (feeling sick) and vomiting (being sick). Besides this, it also helps in the treatment of indigestion.
Preza Dsr Tablet contains domperidone, which prevents nausea and vomiting symptoms by blocking certain receptors (like dopamine and serotonin) that stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. It also acts as a prokinetic agent that increases the upper gastrointestinal tract's motility and helps decrease stomach emptying time.
If you are intolerant to sugars, please inform your doctor before starting Preza Dsr Tablet as it contains lactose. So, to avoid any unpleasant side effects, do as your doctor advises.
Yes, Preza Dsr Tablet can cause dry mouth. In case you feel excessively thirsty, please increase your fluid intake and do frequent mouth rinses.
If you miss a dose, take your medicine as soon as you remember. If it is almost time for your next dose, wait until that is due and continue as usual. Do not take a double dose to make up for a forgotten dose.
Domperidone should be used for the shortest time. It is commonly taken for up to a week. Domperidone can produce irregular heartbeats if taken for an extended time or at a high dose.
No, it is a prescribed medication; it should be used only if specified by the doctor.
Preza Dsr Tablet may cause side effects such as dry mouth, headache or diarrhoea. If these side effects persist or worsen, please consult your doctor.
If you are have any liver or kidney problem, inform your doctor so that an alternative medicine may be recommended.
You are recommended to avoid spicy and oily foods. Limit smoking and alcohol consumption as they may worsen the reflux (stomach acid rising into esophagus). Also, avoid carbonated drinks such as cold drinks and soda as the carbon dioxide gas in them may worsen acid reflux. Limit your intake of chocolate and mint. Some pain killers such as Ibuprofen may increase acidity and worsen the condition. Thus, avoid using these for prolonged duration.
Take Preza Dsr Tablet only for the duration as prescribed by your doctor. If you get relief from your symptoms, consult your doctor for a follow-up, where your doctor may lower the dose. Long term use of Preza Dsr Tablet may cause fractures, low vitamin B12 levels and magnesium levels. You need to be cautious about these and continue to monitor your blood levels regularly and if required your doctor may prescribe the supplements for these deficiencies.
Preza Dsr Tablet is contraindicated in patients with a known hypersensitivity to domperidone or any other inactive ingredients of Preza Dsr Tablet. Patients with underlying liver or kidney disease, should use caution.
Yes, the use of Preza Dsr Tablet can cause diarrhoea. In case if you have diarrhoea, drink lots of water or other fluids. Avoid intake of fatty or fried foods along with Preza Dsr Tablet. If diarrhoea persists and if you notice any signs of dehydration, such as decreased urination with dark colored and strong-smelling urine.
Store Preza Dsr Tablet at room temperature in a cool and dry place. Protect from direct light and moisture. Keep it out of reach of children.
Yes, Preza Dsr Tablet is safe if used as advised by the doctor. Follow your doctor’s instructions.
It is best to take Preza Dsr Tablet before food. Take it the 15 to 30 minutes before a meal or snack or take it as advised by your doctor.
Take Preza Dsr Tablet as advised by your doctor. Swallow it as whole with a glass of water. Do not crush, chew or break it.
You are recommended to take your doctor’s advice before taking Preza Dsr Tablet if you are pregnant or breastfeeding.

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