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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 23, 2024 | 4:50 PM IST
Z Nol 100mg Tablet is used to decrease blood uric acid levels in the body. It is used to treat Gout (increased uric acid leading to inflammation), kidney stones, bladder stones. It contains Allopurinol, which stops uric acid formation inside the body without affecting the essential mechanism of cells and the body. It may cause common side effects such as upset stomach, diarrhoea, skin rash, or drowsiness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Prescription drug

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Manufacturer/Marketer

Arlak Biotech Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Z Nol 100mg Tablet

Z Nol 100mg Tablet belongs to a class of medication called 'enzyme inhibitor', primarily used to decrease blood uric acid levels in the body. It is used to treat Gout (increased uric acid leading to inflammation), kidney stones, bladder stones. Gout is a type of inflammatory reaction (allergic reaction) to uric acid crystals that form and accumulate inside joints, especially  big toe, due to high uric acid levels in the blood resulting in immense pain in joints. 

Z Nol 100mg Tablet contains allopurinol, which works by inhibiting the enzyme xanthine oxidase, the enzyme responsible for the formation of uric acid. It stops uric acid formation inside the body without affecting the essential mechanism of cells and the body. 

Take Z Nol 100mg Tablet as prescribed by your doctor. You are advised to take Z Nol 100mg Tablet for as long as your doctor has prescribed it for you, depending upon your medical condition. The most common side effects of Z Nol 100mg Tablet are upset stomach, diarrhoea, skin rash, drowsiness. Most of these side effects of Z Nol 100mg Tablet are temporary, do not require medical attention, and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. 

Do not take Z Nol 100mg Tablet if you are allergic to any of its ingredients. Z Nol 100mg Tablet contains monohydrated lactose, if you are intolerant to some sugars, call your doctor before taking this drug. If you are pregnant or planning to get pregnant, are breast-feeding ask your doctor for advice before taking this medicine. Drink at least 2-3 litres of water so that you stay hydrated. For people who have kidney disease or renal dysfunction, dose adjustment is required. If you lose unexplained weight, please visit your doctor immediately.

Uses of Z Nol 100mg Tablet

Treatment of Gout (increased uric acid in joints), Kidney stones, Bladder stones.

Medicinal Benefits

Z Nol 100mg Tablet contains an 'enzyme inhibitor', medication, primarily used to decrease blood uric acid levels in the body. In addition to this, it is sometimes also used to treat pain caused by pancreas disease, seizures, and improve survival after bypass surgery. It also prevents the rejection of a kidney transplant. Z Nol 100mg Tablet contains allopurinol, an enzyme inhibitor primarily used to decrease blood uric acid levels in the body. It works by inhibiting the enzyme xanthine oxidase, the enzyme responsible for the formation of uric acid. It stops uric acid formation inside the body without affecting the essential mechanism of cells and the body.

Directions for Use

Take Z Nol 100mg Tablet with or without food as directed by your physician. Swallow it as a whole with a glass of water. Do not crush, chew, or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Z Nol 100mg Tablet

  • Upset stomach
  • Diarrhea
  • Nausea
  • Skin rash
  • Drowsiness
  • Feeling or being sick

Drug Warnings

Do not take Z Nol 100mg Tablet if you are allergic to any of its ingredients. Z Nol 100mg Tablet contains monohydrated lactose; if your doctor mentioned that you are intolerant to some sugars, call your doctor before taking this drug. If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine, you have heart problems or high blood pressure and you take diuretics and/or a medicine called ACE-inhibitors, you have thyroid problems. In rare cases, Z Nol 100mg Tablet can cause bone marrow depression, especially in patients who are already taking that can cause bone marrow depression. For people who have kidney disease or renal dysfunction, dose adjustment is required. If you lose unexplained weight, please visit your doctor immediately. Z Nol 100mg Tablet can cause drowsiness so do not operate machinery or car as it can impair judgment.

Drug Interactions

Drug-Drug Interaction: Z Nol 100mg Tablet is known to interact with a blood thinner (aspirin),  antihypertensive medicines (captopril), anti-bacterial medicines (ampicillin and amoxicillin), medicines used to thin the blood (dicoumarol, phenprocoumon, warfarin), anti-diabetic medicines (chlorpropamide, tolbutamide), anti-epilepsy medicines (phenytoin, carbamazepine), medicines used for chemotherapy (azathioprine, mercaptopurine, cyclophosphamide), immune suppressant medicine (cyclosporine), asthma medicines (theophylline).

Drug-Food Interaction: Z Nol 100mg Tablet is known to interact with alcohol.

Drug-Disease Interaction: Z Nol 100mg Tablet is known to interact in kidney or liver problems, hypertension (high blood pressure), heart problem, thyroid problems, chemotherapy.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • CAPTOPRIL
  • AMPICILLIN
  • AMOXICILLIN
  • DICOUMAROL
  • PHENPROCOUMON
  • WARFARIN
  • CHLORPROPAMIDE
  • TOLBUTAMIDE
  • PHENYTOIN
  • CARBAMAZEPINE
  • AZATHIOPRINE
  • MERCAPTOPURINE
  • CYCLOPHOSPHAMIDE
  • CYCLOSPORINE
  • THEOPHYLLINE

Habit Forming

No

Diet & Lifestyle Advise

  • Purines are found in certain foods such as alcohol, fish, meat, bacon. People with gout should restrict or avoid them greatly.

  • Losing weight helps lower the levels of uric acid.

  • It is also beneficial to drink plenty of fluids. However, the restricted use of alcohol and tobacco is recommended, raising the levels of uric acid.

  • Maintain a diet that is rich in fruits, vegetables, whole grains, and low-fat dairy products.

Special Advise

  • Drink at least 8 glasses of water or other fluids each day while taking Z Nol 100mg Tablet unless directed to do otherwise by your doctor. If you are a kidney patient consult a doctor before any fluid intake. 

  • If you are intolerant to sugars, please mention your doctor before starting Z Nol 100mg Tablet.

  • The doctor will monitor your kidney function constantly before and during you take Z Nol 100mg Tablet.

  • A liver function test should be done regularly to monitor liver enzymes as Z Nol 100mg Tablet can cause liver enzyme fluctuations.

Disease/Condition Glossary

Gout: It is a type of inflammatory (allergic reaction) to uric acid crystals that form and accumulate inside feet, knuckles, and surrounding bone joints due to high uric acid levels in the blood, resulting in immense pain in joints. The pain may be severe, but the condition improves with medication. To avoid bone and cartilage damage and weakening of the kidneys, repeated gout attacks can require long-term medication. In areas such as the wrists, elbows, feet, or earlobes, chronic gout sufferers can feel small hard lumps forming over time in the soft flesh. These deposits are concentrations of uric acid crystals, called tophi, and over time can cause pain and stiffness. 

Kidney stones: It is a problem in which hard deposits occur in the kidney leading to stones. A kidney stone comprises mainly four types of calcium oxalate, uric acid, struvite and cystine. It is due to the increased level of uric acid in the body. As a result, uric acid crystals start depositing in the kidney, known as renal calculi/nephrolithiasis/urolithiasis.

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Alcohol

Unsafe

Z Nol 100mg Tablet should not be taken along with alcohol as it increases uric acid levels.

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Pregnancy

Caution

Z Nol 100mg Tablet is a Category C pregnancy drug. If you are pregnant, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine.

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Breast Feeding

Unsafe

Z Nol 100mg Tablet is excreted in human breast milk, so it is not recommended during breastfeeding.

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Driving

Unsafe

Z Nol 100mg Tablet may make some people feel drowsy or sleepy. Do not drive or operate dangerous machinery if you are affected.

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Liver

Caution

Z Nol 100mg Tablet to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Z Nol 100mg Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Z Nol 100mg Tablet hasn’t been studied and shouldn’t be used in people younger than 18 years to treat gout or kidney stones.

Country of origin

India

Manufacturer/Marketer address

Wintech Pharmaceuticals, Office No. 2 & 3, 3rd Floor, Broadway Shopping Center, Dr. Ambedkar Road, Dadar T.T., Mumbai - 400014 India
Other Info - ZN13246

Author Details

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FAQs

Z Nol 100mg Tablet is used to treat Gout (increased uric acid leading to inflammation), kidney stones, and bladder stones. It decreases blood uric acid levels in the body.
Z Nol 100mg Tablet contains allopurinol, an enzyme inhibitor that works by inhibiting the enzyme xanthine oxidase, the enzyme responsible for uric acid formation. It stops uric acid formation inside the body without affecting the essential mechanism of cells and the body.Â
If you are taking Z Nol 100mg Tablet and it makes you vomit, then your contraceptive pill would not be effective, and it could lead to unwanted pregnancy. If you are of childbearing age, inform your doctor before starting Z Nol 100mg Tablet and use another form of contraceptive like condoms.
Initially, when you start Z Nol 100mg Tablet, it can increase the number of gout attacks. Please do not stop taking Z Nol 100mg Tablet on having an acute attack (sudden attack) of gout as it can make the attack even worse. Co-administration with an anti-inflammatory agent (colchicine) is recommended and slowly increasing the dose of Z Nol 100mg Tablet.
Generally, when Z Nol 100mg Tablet is given to elderly patients (above 65 years), the dose is lowered depending upon the patient's condition. Also, if mention all underlining disease you suffer from which could affect Z Nol 100mg Tablet, the dose will be adjusted accordingly by your doctor
Yes, Z Nol 100mg Tablet can cause drowsiness in some people. It can even make you feel dizzy or have a problem with coordination. It is advisable to avoid driving or operate machinery to avoid any unpleasant side effects.
No, Z Nol 100mg Tablet is not an anti-inflammatory medicine. It works by inhibiting the enzyme xanthine oxidase, the enzyme responsible for the formation of uric acid. It stops uric acid formation inside the body without affecting the essential mechanism of cells and the body.Â
It may take several weeks to lower the uric acid levels, before you start feeling better or notice any significant reduction in attacks of gout.
Z Nol 100mg Tablet may cause side effects such as nausea, vomiting, diarrhoea, stomach upset, or drowsiness. If these side effects persist or worsen, please consult your doctor.
It is preferable to take Z Nol 100mg Tablet after a meal to prevent stomach upset. But take it at the same time every day to help you remember to take it. However, follow your doctor’s instructions carefully.
You may experience an increase in gout attacks after you have started taking Z Nol 100mg Tablet. However, with several months of therapy, these attacks typically become less severe and shorter. This increase in attacks could be due to slow breakdown of uric acid crystals, causing fluctuations in blood uric acid levels. If you still have any concerns, please discuss with your doctor.
If you consume alcohol while taking Z Nol 100mg Tablet, it increases uric acid levels and worsen your condition. Therefore, avoid alcohol consumption while taking Z Nol 100mg Tablet.
If you forget to take a dose of Z Nol 100mg Tablet, take it as soon as you remember. But, if it is time for your next dose, skip the missed dose and take your regular dose. Do not take a double dose to make up for a forgotten dose.
Store Z Nol 100mg Tablet in a cool, dry and dark place. Protect from direct sunlight and moisture. Keep it out of sight and reach of children.

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