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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Puril 100 mg Tablet is used to decrease blood uric acid levels in the body. It is used to treat Gout (increased uric acid leading to inflammation), kidney stones, bladder stones. It contains Allopurinol, which stops uric acid formation inside the body without affecting the essential mechanism of cells and the body. It may cause common side effects such as upset stomach, diarrhoea, skin rash, or drowsiness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

ALLOPURINOL-100MG

Manufacturer/Marketer :

Marcus Pharma

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Puril 100 mg Tablet

Puril 100 mg Tablet belongs to a class of medication called 'enzyme inhibitor', primarily used to decrease blood uric acid levels in the body. It is used to treat Gout (increased uric acid leading to inflammation), kidney stones, bladder stones. Gout is a type of inflammatory reaction (allergic reaction) to uric acid crystals that form and accumulate inside joints, especially  big toe, due to high uric acid levels in the blood resulting in immense pain in joints. 

Puril 100 mg Tablet contains allopurinol, which works by inhibiting the enzyme xanthine oxidase, the enzyme responsible for the formation of uric acid. It stops uric acid formation inside the body without affecting the essential mechanism of cells and the body. 

Take Puril 100 mg Tablet as prescribed by your doctor. You are advised to take Puril 100 mg Tablet for as long as your doctor has prescribed it for you, depending upon your medical condition. The most common side effects of Puril 100 mg Tablet are upset stomach, diarrhoea, skin rash, drowsiness. Most of these side effects of Puril 100 mg Tablet are temporary, do not require medical attention, and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. 

Do not take Puril 100 mg Tablet if you are allergic to any of its ingredients. Puril 100 mg Tablet contains monohydrated lactose, if you are intolerant to some sugars, call your doctor before taking this drug. If you are pregnant or planning to get pregnant, are breast-feeding ask your doctor for advice before taking this medicine. Drink at least 2-3 litres of water so that you stay hydrated. For people who have kidney disease or renal dysfunction, dose adjustment is required. If you lose unexplained weight, please visit your doctor immediately.

Uses of Puril 100 mg Tablet

Treatment of Gout (increased uric acid in joints), Kidney stones, Bladder stones.

Directions for Use

Take Puril 100 mg Tablet with or without food as directed by your physician. Swallow it as a whole with a glass of water. Do not crush, chew, or break it.

Medicinal Benefits

Puril 100 mg Tablet contains an 'enzyme inhibitor', medication, primarily used to decrease blood uric acid levels in the body. In addition to this, it is sometimes also used to treat pain caused by pancreas disease, seizures, and improve survival after bypass surgery. It also prevents the rejection of a kidney transplant. Puril 100 mg Tablet contains allopurinol, an enzyme inhibitor primarily used to decrease blood uric acid levels in the body. It works by inhibiting the enzyme xanthine oxidase, the enzyme responsible for the formation of uric acid. It stops uric acid formation inside the body without affecting the essential mechanism of cells and the body.

How Puril 100 mg Tablet Works

Puril 100 mg Tablet contains allopurinol, which works by inhibiting the enzyme xanthine oxidase, the enzyme responsible for the formation of uric acid. It stops uric acid formation inside the body without affecting the essential mechanism of cells and the body.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Puril 100 mg Tablet

  • Upset stomach
  • Diarrhea
  • Nausea
  • Skin rash
  • Drowsiness
  • Feeling or being sick

What if I have taken an overdose of Puril 100 mg Tablet

Do not take more than the prescribed dose of Puril 100 mg Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Puril 100 mg Tablet if you are allergic to any of its ingredients. Puril 100 mg Tablet  contains monohydrated lactose; if your doctor mentioned that you are intolerant to some sugars, call your doctor before taking this drug. If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine, you have heart problems or high blood pressure and you take diuretics and/or a medicine called ACE-inhibitors, you have thyroid problems. In rare cases, Puril 100 mg Tablet can cause bone marrow depression, especially in patients who are already taking that can cause bone marrow depression. For people who have kidney disease or renal dysfunction, dose adjustment is required. If you lose unexplained weight, please visit your doctor immediately. Puril 100 mg Tablet can cause drowsiness so do not operate machinery or car as it can impair judgment.

Drug-Drug Interactions

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AllopurinolDidanosine
Critical
AllopurinolPegloticase
Severe

Drug-Drug Interactions

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AllopurinolDidanosine
Critical
How does the drug interact with Puril 100 mg Tablet 10's:
When Didanosine is taken with Puril 100 mg Tablet 10's, can increase the blood levels of didanosine.

How to manage the interaction:
Taking Puril 100 mg Tablet 10's with Didanosine lead to an interaction, please consult a doctor before taking it. Do not discontinue the medication without consulting a doctor.
AllopurinolPegloticase
Severe
How does the drug interact with Puril 100 mg Tablet 10's:
Co-administration of Puril 100 mg Tablet 10's with Pegloticase can increase the chances of side effects.

How to manage the interaction:
Co-administration of Puril 100 mg Tablet 10's with Pegloticase can possibly result in an interaction, but it can be taken if your doctor has advised it. This is more common in people who already have high uric acid levels, which may not be obvious if they are taking other uric acid-lowering medications. Do not stop using any medications without first talking to your doctor.
AllopurinolMercaptopurine
Severe
How does the drug interact with Puril 100 mg Tablet 10's:
Co-administration of Puril 100 mg Tablet 10's with Mercaptopurine together may increase the effects of mercaptopurine.

How to manage the interaction:
If you take Puril 100 mg Tablet 10's and Mercaptopurine together, a doctor may adjust the dose or recommend special tests to use both medications safely. However, contact a doctor immediately if you develop any symptoms such as chills, fever, sore throat, mouth sores, body pains, weakness, muscle pain, easy bruising or bleeding, pale stools, darkened urine, or severe nausea, vomiting, and diarrhea. Do not discontinue any medications without a doctor's advice.
AllopurinolTrandolapril
Severe
How does the drug interact with Puril 100 mg Tablet 10's:
Co-administration of Puril 100 mg Tablet 10's with Trandolapril may increase the risk of severe allergic reactions and infections.

How to manage the interaction:
Although there is a possible interaction between Puril 100 mg Tablet 10's and Trandolapril you can take these medicines together if prescribed by your doctor. However, if you develop throat tightness, shortness of breath, itching, rash, swelling of the face, lips, or tongue, fever, and/or muscle pain or weakness, contact your doctor immediately. Also let your doctor know if you notice signs of infection or experience chills, fever, sore throat, extreme tiredness, body pains, or other flu-like symptoms. Do not discontinue the medication without consulting a doctor.
AllopurinolMoexipril
Severe
How does the drug interact with Puril 100 mg Tablet 10's:
Co-administration of Puril 100 mg Tablet 10's with Moexipril may increase the risk of severe allergic reactions and infections.

How to manage the interaction:
Although there is a possible interaction between Puril 100 mg Tablet 10's and Moexipril, you can take these medicines together if prescribed by your doctor. However, if you develop throat tightness, shortness of breath, itching, rash, swelling of the face, lips, or tongue, fever, and/or muscle pain or weakness, contact your doctor immediately. Also, let your doctor know if you notice signs of infection or experience chills, fever, sore throat, extreme tiredness, body pains, or other flu-like symptoms. Do not discontinue any medications without consulting a doctor.
AllopurinolAzathioprine
Severe
How does the drug interact with Puril 100 mg Tablet 10's:
Co-administration of Puril 100 mg Tablet 10's with Azathioprine may increase the effects of azathioprine.

How to manage the interaction:
There may be a possibility of interaction between Azathioprine and Puril 100 mg Tablet 10's, but it can be taken if prescribed by a doctor. However, if you experience chills, fever, body pains, sore throat, weakness, muscle pain, mouth sores, easy bruising or bleeding, pale stools, darkened urine, or severe nausea, vomiting, and diarrhoea, consult a doctor. Do not stop using any medications without a doctor's advice.
AllopurinolFosinopril
Severe
How does the drug interact with Puril 100 mg Tablet 10's:
Co-administration of Puril 100 mg Tablet 10's with Fosinopril may increase the risk of severe allergic reactions and infections.

How to manage the interaction:
Although there is a possible interaction between Puril 100 mg Tablet 10's and Fosinopril, you can take these medicines together if prescribed by your doctor. However, if you develop throat tightness, shortness of breath, itching, rash, swelling of the face, lips, or tongue, fever, and/or muscle pain or weakness, contact your doctor immediately. Also let your doctor know if you notice signs of infection or experience chills, fever, sore throat, extreme tiredness, body pains, or other flu-like symptoms. Do not discontinue any medications without consulting a doctor.
AllopurinolQuinapril
Severe
How does the drug interact with Puril 100 mg Tablet 10's:
Co-administration of Puril 100 mg Tablet 10's with Quinapril may increase the risk of severe allergic reactions and infections.

How to manage the interaction:
Although there is a possible interaction between Puril 100 mg Tablet 10's and Quinapril, you can take these medicines together if prescribed by your doctor. However, if you develop throat tightness, shortness of breath, itching, rash, swelling of the face, lips, or tongue, fever, and/or muscle pain or weakness, contact your doctor immediately. Also, let your doctor know if you notice signs of infection or experience chills, fever, sore throat, extreme tiredness, body pains, or other flu-like symptoms. Do not discontinue any medications without consulting a doctor.
AllopurinolEnalapril
Severe
How does the drug interact with Puril 100 mg Tablet 10's:
Coadministration of Puril 100 mg Tablet 10's with Enalapril may increase the risk of severe allergic reactions and infections.

How to manage the interaction:
Although there is a possible interaction between Puril 100 mg Tablet 10's and Enalapril, you can take these medicines together if prescribed by your doctor. However, if you develop throat tightness, shortness of breath, itching, rash, swelling of the face, lips, or tongue, fever, and/or muscle pain or weakness, contact your doctor immediately. Also, let your doctor know if you notice signs of infection or experience chills, fever, sore throat, extreme tiredness, body pains, or other flu-like symptoms. Do not stop using any medications without consulting your doctor.
AllopurinolRamipril
Severe
How does the drug interact with Puril 100 mg Tablet 10's:
Co-administration of Puril 100 mg Tablet 10's with Ramipril may increase the risk of severe allergic reactions and infections.

How to manage the interaction:
Although there is a possible interaction between Puril 100 mg Tablet 10's and Ramipril, you can take these medicines together if prescribed by your doctor. However, if you develop throat tightness, shortness of breath, itching, rash, swelling of the face, lips, or tongue, fever, and/or muscle pain or weakness, contact your doctor immediately. Also, let your doctor know if you notice signs of infection or experience chills, fever, sore throat, extreme tiredness, body pains, or other flu-like symptoms. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Purines are found in certain foods such as alcohol, fish, meat, bacon. People with gout should restrict or avoid them greatly.

  • Losing weight helps lower the levels of uric acid.

  • It is also beneficial to drink plenty of fluids. However, the restricted use of alcohol and tobacco is recommended, raising the levels of uric acid.

  • Maintain a diet that is rich in fruits, vegetables, whole grains, and low-fat dairy products.

Habit Forming

No

Therapeutic Class

GOUT THERAPY

Puril 100 mg Tablet Substitute

Substitutes safety advice
  • Zyloric 100 Tablet 10's

    1.89per tablet
  • ZYRIK 100MG TABLET

    1.89per tablet
  • Logout 100mg Tablet 10's

    2.00per tablet
  • Gurik 100mg Tablet

    1.71per tablet
  • ALORIC 100MG TABLET

    14.36per tablet
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Alcohol

Unsafe

Puril 100 mg Tablet should not be taken along with alcohol as it increases uric acid levels.

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Pregnancy

Caution

Puril 100 mg Tablet is a Category C pregnancy drug. If you are pregnant, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine.

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Breast Feeding

Unsafe

Puril 100 mg Tablet is excreted in human breast milk, so it is not recommended during breastfeeding.

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Driving

Unsafe

Puril 100 mg Tablet may make some people feel drowsy or sleepy. Do not drive or operate dangerous machinery if you are affected.

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Liver

Caution

Puril 100 mg Tablet to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Puril 100 mg Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Puril 100 mg Tablet hasn’t been studied and shouldn’t be used in people younger than 18 years to treat gout or kidney stones.

FAQs

Puril 100 mg Tablet is used to treat Gout (increased uric acid leading to inflammation), kidney stones, and bladder stones. It decreases blood uric acid levels in the body.
Puril 100 mg Tablet contains allopurinol, an enzyme inhibitor that works by inhibiting the enzyme xanthine oxidase, the enzyme responsible for uric acid formation. It stops uric acid formation inside the body without affecting the essential mechanism of cells and the body.Â
If you are taking Puril 100 mg Tablet and it makes you vomit, then your contraceptive pill would not be effective, and it could lead to unwanted pregnancy. If you are of childbearing age, inform your doctor before starting Puril 100 mg Tablet and use another form of contraceptive like condoms.
Initially, when you start Puril 100 mg Tablet , it can increase the number of gout attacks. Please do not stop taking Puril 100 mg Tablet on having an acute attack (sudden attack) of gout as it can make the attack even worse. Co-administration with an anti-inflammatory agent (colchicine) is recommended and slowly increasing the dose of Puril 100 mg Tablet .
Generally, when Puril 100 mg Tablet is given to elderly patients (above 65 years), the dose is lowered depending upon the patient's condition. Also, if mention all underlining disease you suffer from which could affect Puril 100 mg Tablet , the dose will be adjusted accordingly by your doctor
Yes, Puril 100 mg Tablet can cause drowsiness in some people. It can even make you feel dizzy or have a problem with coordination. It is advisable to avoid driving or operate machinery to avoid any unpleasant side effects.
No, Puril 100 mg Tablet is not an anti-inflammatory medicine. It works by inhibiting the enzyme xanthine oxidase, the enzyme responsible for the formation of uric acid. It stops uric acid formation inside the body without affecting the essential mechanism of cells and the body.Â
It may take several weeks to lower the uric acid levels, before you start feeling better or notice any significant reduction in attacks of gout.
Puril 100 mg Tablet may cause side effects such as nausea, vomiting, diarrhoea, stomach upset, or drowsiness. If these side effects persist or worsen, please consult your doctor.
It is preferable to take Puril 100 mg Tablet after a meal to prevent stomach upset. But take it at the same time every day to help you remember to take it. However, follow your doctor’s instructions carefully.
You may experience an increase in gout attacks after you have started taking Puril 100 mg Tablet . However, with several months of therapy, these attacks typically become less severe and shorter. This increase in attacks could be due to slow breakdown of uric acid crystals, causing fluctuations in blood uric acid levels. If you still have any concerns, please discuss with your doctor.
If you consume alcohol while taking Puril 100 mg Tablet , it increases uric acid levels and worsen your condition. Therefore, avoid alcohol consumption while taking Puril 100 mg Tablet .
If you forget to take a dose of Puril 100 mg Tablet , take it as soon as you remember. But, if it is time for your next dose, skip the missed dose and take your regular dose. Do not take a double dose to make up for a forgotten dose.
Store Puril 100 mg Tablet in a cool, dry and dark place. Protect from direct sunlight and moisture. Keep it out of sight and reach of children.

Country of origin

India

Manufacturer/Marketer address

No. 1935, No. 222, 2Nd Floor, Fountain Electric Market, Bhagirath Palace, Chandni Chowk,New Delhi-110006
Other Info - PUR0039

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