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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Xygrel 60 Tablet is taken to prevent heart attack or stroke in people at high risk of heart disease. It helps to prevent blood clots in people with acute coronary syndrome (heart doesn't receive enough oxygen) who have had stents placed in blood vessels in their heart. It contains Ticagrelor, which prevents blood clot formation in the blood vessels by making platelets less sticky. In some cases, you may experience dyspnea (shortness of breath), tightness in the chest, blurred vision, nosebleeds, dizziness, faintness, or lightheadedness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

TICAGRELOR-60MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Xygrel 60 Tablet

Xygrel 60 Tablet belongs to the antiplatelet drugs (blood thinners) primarily taken to prevent heart attack or stroke in people at high risk of heart disease. Xygrel 60 Tablet  helps to prevent blood clots in people with acute coronary syndrome (heart doesn't receive enough oxygen) who have had stents placed in blood vessels in their heart. A heart attack occurs when a blood clot blocks the blood flow to the heart. This blockage of arteries is often an accumulation of cholesterol, fat, and other substances, which form plaque in the arteries that feed the heart (coronary arteries). A heart attack signs include chest pain, upper body pain, sweating, nausea, fatigue, and trouble breathing.

Xygrel 60 Tablet contains Ticagrelor, which is a blood thinner that prevents clot formation in the blood vessels. Platelets are blood cells that stick together and block any cuts and breaks in blood vessels. But platelets can stick together inside already narrowed blood vessels to form a clot in people at risk of heart attack or stroke. The clot can stop blood from flowing to the heart or brain and cause a heart attack or stroke. Here, Xygrel 60 Tablet slows the blood's clotting action by making platelets less sticky.

Your doctor will advise you how often you take Xygrel 60 Tablet based on your medical condition. In some cases, you may experience dyspnea (shortness of breath), tightness in the chest, blurred vision, nosebleeds, dizziness, faintness, or lightheadedness. If side effects are persistent, talk to your doctor. Xygrel 60 Tablet may cause you to bleed more easily. You should not take Xygrel 60 Tablet if you have bleeding in your brain, a problem with blood flow, or any other bleeding risk factor.

Before taking the Xygrel 60 Tablet , let your doctor know about all your allergic or hypersensitivity reactions to medicines or food. Xygrel 60 Tablet should not be stopped even if you feel better without consulting your doctor, as stopping a sudden intake of Xygrel 60 Tablet may worsen your condition and increase the risk of a future heart attack. The patient should inform the doctor that they are taking Xygrel 60 Tablet before any surgery is scheduled or any new medicine is taken. Don't take Xygrel 60 Tablet before or after having heart bypass surgery. Before using Xygrel 60 Tablet , consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Uses of Xygrel 60 Tablet

Prevention of Heart attack, Stroke, Acute Coronary Syndrome.

Directions for Use

Tablet: Swallow it as a whole with water; do not crush, break or chew it.Orodispersible tablet/mouth-dissolving tablet: Keep the tablet in the mouth and allow it to disintegrate. Do not swallow as a whole. Avoid handling the strip with wet hands.

Medicinal Benefits

Xygrel 60 Tablet is an antiplatelet (blood thinner) and plays a vital role in preventing the formation of harmful blood clots in your blood vessels. Xygrel 60 Tablet work by preventing platelets from sticking together, thereby decreasing the formation of harmful blood clots. Thus, it reduces the risk of heart attack, stroke, and acute coronary syndrome (heart doesn't receive enough oxygen or blood) in heart disease patients and patients who have undergone recent heart surgery with a stent.

How Xygrel 60 Tablet Works

Xygrel 60 Tablet contains Ticagrelor, which is a blood thinner that prevents clot formation in the blood vessels. Platelets are blood cells that stick together and block any cuts and breaks in blood vessels. But platelets can stick together inside already narrowed blood vessels to form a clot in people at risk of heart attack or stroke. The clot can stop blood from flowing to the heart or brain and cause a heart attack or stroke. Here, Xygrel 60 Tablet slows the blood's clotting action by making platelets less sticky.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Xygrel 60 Tablet

  • Dyspnea (shortness of breath)
  • Tightness in the chest
  • Blurred vision
  • Nosebleeds
  • Dizziness
  • Faintness or lightheadedness when getting up suddenly from a lying or sitting position
  • High level of uric acid in your blood
  • Severe pain and swelling in your joints – these are signs of gout
  • Bruising
  • Headache
  • Diarrhoea
  • Indigestion
  • Constipation
  • Bleeding after surgery or from cuts (for example, while shaving) and wounds more than is normal
  • Bleeding from your stomach lining (ulcer)
  • Bleeding gums

What if I have taken an overdose of Xygrel 60 Tablet

Do not take more than the prescribed dose of Xygrel 60 Tablet as it may cause overdose resulting in excessive bleeding. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

You should avoid taking Xygrel 60 Tablet if you are allergic to Xygrel 60 Tablet or any active and inactive ingredients present in it.  Let your doctor know if you have a medical condition that causes bleeding such as hemophilia, stomach ulcer, or bleeding in your head or bowel. Caution is required before giving Xygrel 60 Tablet to the kidney or liver problems patients. People affected with respiratory problems like asthma, nasal polyps, or rhinitis should consult a doctor before intake of Xygrel 60 Tablet . Xygrel 60 Tablet is not recommended for the breastfeeding mother as it passes into the breast milk. The safety and effectiveness in children less than 18 years of age have not been established, so Xygrel 60 Tablet should not be given to them.

Drug-Drug Interactions

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TicagrelorKetoconazole
Critical
TicagrelorTelithromycin
Critical

Drug-Drug Interactions

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TicagrelorKetoconazole
Critical
How does the drug interact with Xygrel 60 Tablet 10's:
Co-administration of Xygrel 60 Tablet 10's with ketoconazole can cause severe bleeding.

How to manage the interaction:
Taking Xygrel 60 Tablet 10's with Ketoconazole is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TicagrelorTelithromycin
Critical
How does the drug interact with Xygrel 60 Tablet 10's:
Using Xygrel 60 Tablet 10's together with telithromycin cause increase the blood levels of Xygrel 60 Tablet 10's.

How to manage the interaction:
Taking Xygrel 60 Tablet 10's with Telithromycin is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
TicagrelorConivaptan
Critical
How does the drug interact with Xygrel 60 Tablet 10's:
Co-administration of Xygrel 60 Tablet 10's with Conivaptan can increase the risk of bleeding.

How to manage the interaction:
Taking Xygrel 60 Tablet 10's with Conivaptan is not recommended, please consult your doctor before taking it. However, if you experience unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
TicagrelorPosaconazole
Critical
How does the drug interact with Xygrel 60 Tablet 10's:
Co-administration of posaconazole with Xygrel 60 Tablet 10's can increase the risk of bleeding.

How to manage the interaction:
Taking Xygrel 60 Tablet 10's with Posaconazole is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
TicagrelorItraconazole
Critical
How does the drug interact with Xygrel 60 Tablet 10's:
The blood levels and effects of Xygrel 60 Tablet 10's may be greatly increased when combined with itraconazole.

How to manage the interaction:
Itraconazole and Xygrel 60 Tablet 10's may interact, however if prescribed by a physician, they can be used together. While receiving therapy, you should consult a doctor if you develop any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Without consulting a doctor, never stop taking any medication.
TicagrelorRitonavir
Critical
How does the drug interact with Xygrel 60 Tablet 10's:
Taking Xygrel 60 Tablet 10's with Ritonavir may significantly increase the blood levels of Xygrel 60 Tablet 10's.

How to manage the interaction:
Taking Xygrel 60 Tablet 10's with Ritonavir is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
TicagrelorIndinavir
Critical
How does the drug interact with Xygrel 60 Tablet 10's:
Using Xygrel 60 Tablet 10's together with indinavir can cause risk of bleeding.

How to manage the interaction:
Taking Xygrel 60 Tablet 10's with Indinavir is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
TicagrelorVoriconazole
Critical
How does the drug interact with Xygrel 60 Tablet 10's:
Using Xygrel 60 Tablet 10's together with Voriconazole can significantly increase the blood levels of Xygrel 60 Tablet 10's.

How to manage the interaction:
Taking Xygrel 60 Tablet 10's with Voriconazole is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience vomiting, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
TicagrelorMifepristone
Critical
How does the drug interact with Xygrel 60 Tablet 10's:
Co-administration of Mifepristone with Xygrel 60 Tablet 10's can increase the risk of vaginal bleeding in women.

How to manage the interaction:
Taking Xygrel 60 Tablet 10's with Mifepristone is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience any symptoms like heavy period bleed for more than 7 days, weakness, tiredness, shortness of breath or paleness. Do not discontinue any medications without consulting a doctor.
TicagrelorEnoxaparin
Severe
How does the drug interact with Xygrel 60 Tablet 10's:
Taking Xygrel 60 Tablet 10's with enoxaparin may increase the risk of bleeding.

How to manage the interaction:
Although taking Enoxaparin with Xygrel 60 Tablet 10's together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, contact a doctor immediately. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Reducing weight and having a healthy BMI is very important in enhancing cardiac health.

  • 30 minutes of daily physical exercise can go a long way in preventing heart disease.

  • Avoid smoking to improve cardiac health.

  • Invest in a healthy, balanced diet. Avoid fatty foods, keep your cholesterol in check and load up on the green leafy vegetables, fish, lean meats, nuts and dry fruits. 

  • Reducing stress is very important in keeping a healthy heart. Try yoga and meditation for a relaxed state of mind.

Habit Forming

No

Therapeutic Class

PLATELET AGGREGATION INHIBITOR

Xygrel 60 Tablet Substitute

Substitutes safety advice
  • Brilinta 60 mg Tablet 14's

    by AYUR

    32.66per tablet
  • Axcer 60 mg Tablet 14's

    by AYUR

    27.03per tablet
  • Torplat 60 mg Tablet 10's

    19.67per tablet
  • Ticavic-60mg Tablet 10's

    by AYUR

    17.91per tablet
  • Vasoglor 60 Tablet 10's

    20.12per tablet
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Alcohol

Unsafe

It is unsafe to consume alcohol since it may worsen the side effects like dizziness and increases blood pressure.

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Pregnancy

Caution

Please consult the doctor. There are no adequate and well-controlled studies on pregnant women. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Xygrel 60 Tablet may pass into breast milk and may cause side effects in a breastfed child. Please consult your doctor before starting Xygrel 60 Tablet .

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Driving

Caution

Do not drive or operate machinery if you experience dizziness or drowsiness while using Xygrel 60 Tablet .

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Liver

Caution

Let your doctor know if you had or have any history of liver disease or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Xygrel 60 Tablet . However, Xygrel 60 Tablet is not recommended in patients with severe liver problems.

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Kidney

Caution

Let your doctor know if you had or have any history of kidney diseases/conditions. Your doctor will weigh the benefits and potential risks before prescribing Xygrel 60 Tablet . However, Xygrel 60 Tablet is not recommended in patients with severe kidney problems.

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Children

Caution

Xygrel 60 Tablet is not recommended for children below the age of 18 years. The safety and effectiveness of Xygrel 60 Tablet have not been established in children.

FAQs

Xygrel 60 Tablet is primarily used to prevent heart attack or stroke in people at high risk of heart disease. It helps to prevent blood clots in people with acute coronary syndrome (the heart doesn't receive enough oxygen) who have had stents placed in blood vessels in their heart.
If the Xygrel 60 Tablet is taken every day, the Xygrel 60 Tablet stops platelets from clumping together to form unwanted blood clots and prevents heart attacks and strokes.
Yes, taking Xygrel 60 Tablet can increase the risk of bleeding. So, please be very cautious while cutting fingernails or toenails, shaving, or using sharp objects to avoid bleeding.
Please consult your doctor if Xygrel 60 Tablet needs to be stopped before undergoing surgery. The doctor might ask you to stop taking Xygrel 60 Tablet a few days before surgery since it can cause an increased risk of bleeding during surgery.
There might be a problem if you take herbal therapies with Xygrel 60 Tablet , especially those that affect blood like Ginkgo Biloba, Grapefruits, St John's wort plant extract used as an antidepressant. Taking together can increase your risk of bleeding. Tell your doctor if you are using any herbal supplements before taking Xygrel 60 Tablet .
No, Xygrel 60 Tablet may make it harder to breathe. Consult your doctor if the problem persists, he/she may adjust the dose or prescribe an alternative medicine.
Do not drink grapefruit juice while taking Xygrel 60 Tablet . Grapefruit juice may increase the blood-thinning effect of the medicine.
Xygrel 60 Tablet contains ticagrelor, which when taken with clopidogrel may increase the risk of bleeding. Consult the doctor before taking other medicines with Xygrel 60 Tablet .
Xygrel 60 Tablet should not be discontinued without a doctor's consultation. Stopping Xygrel 60 Tablet might increase the risk of a heart attack or stroke.
Xygrel 60 Tablet may cause blood in urine. Consult the doctor if you experience this.
Xygrel 60 Tablet might lower the blood pressure. Let the doctor know if you are taking anti-hypertensives (blood pressure-lowering medicines). Regular monitoring of blood pressure levels is advised.
Xygrel 60 Tablet can be taken with other medicines if prescribed by the doctor. Before starting Xygrel 60 Tablet inform the doctor if you are taking any other medicines to prevent interactions.
Xygrel 60 Tablet is an antiplatelet medicine which inhibits the aggregation of platelets that may cause a heart attack or stroke.
Limit alcohol consumption with Xygrel 60 Tablet as it might increase the risk of bleeding.
Xygrel 60 Tablet may cause significant, sometimes fatal bleeding. Inform the doctor if you have/had a condition that causes you to bleed more easily than normal; bleeding in your stomach, intestines, or brain; stomach ulcer; polyps (abnormal growths in the lining of the large intestine); a stroke or mini-stroke; or liver disease. Seek immediate medical attention if you experience unexplained, severe, long-lasting, or uncontrollable bleeding; red or black, tarry stools; pink or brown urine; vomit that is bloody or that looks like coffee grounds; or coughing up blood or blood clots.
Xygrel 60 Tablet works within 30 minutes of taking the first dose.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - XYG0004

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